Use of Stiripentol in Patients with Dravet Syndrome: Common Practice Among Experts in Spain by Juan José García-Peñas, Rocío Calvo-Medina, Adrián García-Ron, Antonio Gil-Nagel, Vicente Villanueva, Rocío Sánchez-Carpintero

“…., fenfluramine), at initiation and during stiripentol treatment, can mitigate drug interactions, thereby increasing the long-term tolerability of stiripentol treatment. In specific cases, stiripentol doses of > 50 mg/kg/day may be contemplated, and acute stiripentol administration may be considered to control refractory status epilepticus. …”
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Hymecromone Efficacy in the Treatment of Biliary Pancreatitis by A. V. Okhlobystin, M. A. Tatarkina, O. Z. Okhlobystina, S. A. Budzinskiy, P. V. Pavlov, L. A. Labut

“…Hymecromone therapy demonstrates a good level of tolerability and safety, normalizes the motor function of the biliary tract and sphincter tone over a short period of time, and relieves CP symptoms.…”
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Application of efgartigimod in Chinese patients with myasthenia gravis: a single-center real-world prospective study by Geke Zhu, Han Zhou, Wanying Wang, Yongbo Ma, Xiangtao Nie, Wenjing Qi, Lei Hao, Xiuming Guo

“…Background: China has a large number of myasthenia gravis (MG) patients, creating an urgent need for rapid and tolerable treatment options. As the first-approved Fc receptor antagonist, efgartigimod has bright prospects for treating MG. …”
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Outcomes for Dostarlimab and Real-World Treatments in Post-platinum Patients With Advanced/Recurrent Endometrial Cancer: The GARNET Trial Versus a US Electronic Health Record-Based... by Scott Goulden, Qin Shen, Robert L. Coleman, Cara Mathews, Matthias Hunger, Ankit Pahwa, Rene Schade

“…Additionally, patients had a long TTD when treated with dostarlimab, suggesting a favorable tolerability profile. **Conclusion:** Patients with advanced or recurrent EC receiving dostarlimab in GARNET had significantly lower risk of death than those receiving real-world non-anti-PD-(L)1/2 treatments.…”
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PENANAMAN NILAI-NILAI MODERASI BERAGAMA PADA KARAKTER PESERTA DIDIK DI SDN 4 SILIRAGUNG BANYUWANGI by Ali Makrus, Hepni Hepni, Mustajab Mustajab, Lailatul Usriyah

“…Second, the value of tolerance faces challenges in the environment of SDN 4 Siliragung's children, especially regarding differences in achievements and abilities. …”
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Heterologous Expression and Adaptive Evolution of ε-Poly-lysine Synthase Gene in <i>Corynebacterium glutamicum</i> by Long Pan, Yihang Chen, Aimei Liao, Yinchen Hou, Jihong Huang

“…Finally, through adaptive evolution of the recombinant strain, the ε-PL tolerance of the recombinant strain was increased to 1.3 g/L, and the yield of ε-PL ultimately reached 0.34 g/L, which increased by 54.55% compared to the initial strain. …”
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Monthly Intramuscular Neridronate for the Treatment of Postmenopausal Osteoporosis: Results of a 6-Year Prospective Italian Study by L. Guiducci, C. Vassalle, P. Parchi, S. Maffei

“…Oral bisphosphonates (BPs) are the most commonly used medications for osteoporosis (OP), but their poor gastrointestinal (GI) absorption and tolerance hamper compliance. Intramuscular (IM) neridronate (NE), an amino-BP, is an easy-to-administer, effective, and safe alternative to oral BPs. …”
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The TikTok Addiction Scale: Development and validation by Petros Galanis, Aglaia Katsiroumpa, Ioannis Moisoglou, Olympia Konstantakopoulou

“…Factor analysis revealed a six-factor structure, (1) salience, (2) mood modification, (3) tolerance, (4) withdrawal symptoms, (5) conflict, and (6) relapse, which accounted for 80.70% of the total variance. …”
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Effect of Multiradiance Low-Level Laser Therapy and Topical Silver Sulfadiazine on Healing Characteristics of Dermal Wounds in Marine Toads (Rhinella marina) by Kate E. Archibald, Tara Harrison, Brigid Troan, Dustin Smith, Larry J. Minter

“…Laser therapy and SSD, at the doses and dosing schedule utilized in this pilot study, appear to be safe and well-tolerated treatments in marine toads, but may not be warranted for uncomplicated skin wounds in this species.…”
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An Efficient and Accurate Adaptive Time-Stepping Method for the Landau–Lifshitz Equation by Hyundong Kim, Soobin Kwak, Moumni Mohammed, Seungyoon Kang, Seokjun Ham, Junseok Kim

“…Our proposed algorithm strategically selects an adaptive time step, ensuring that the maximum displacement falls within a predefined tolerance threshold. Furthermore, this adaptive approach allows the utilization of larger time steps near equilibrium states and results in faster computations. …”
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Genotypic Variability in Some Morpho-Physiological Traits in Different Environments and Their Relationship with Cassava (Manihot esculenta Crantz) Root Yield by Joseph Adjebeng-Danquah, Isaac Kwadwo Asante, Joseph Manu-Aduening, Richard Yaw Agyare, Vernon Edward Gracen, Samuel Kwame Offei

“…These can be used as secondary traits to select drought-tolerant genotypes. From this study, the GGE biplot was useful in identifying traits associated with specific genotypes in different environments to aid in selection. …”
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Fast Hadamard-Encoded 7T Spectroscopic Imaging of Human Brain by Chan Hong Moon, Frank S. Lieberman, Hoby P. Hetherington, Jullie W. Pan

“…<b>Conclusions</b>: With minimal gradient demands and fast acquisition times, the 2.2 min to 9 min for single- to four-slice RSI acquisitions are well tolerated by healthy subjects and tumor patients, and show results that are consistent with clinical outcomes.…”
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Perioperative or neo/adjuvant chemoimmunotherapy versus chemotherapy for resectable non-small cell lung cancer: a systematic review and network meta-analysis by Qiong Zhang, Jia Duan, Yuanmei Zhang, Lei Yang, Duo Li

“…However, these immunotherapy combinations are generally well tolerated. Conclusions The findings indicate that neoadjuvant and perioperative immunotherapy combined with chemotherapy can significantly improve overall survival in patients with resectable NSCLC compared to standard chemotherapy. …”
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Integrated metabolomic and transcriptomic analysis of anthocyanin metabolism in wheat pericarp by Jiao Wang, Lei Sun, Bo Jiao, Pu Zhao, Tianyun Xu, Sa Gu, Chenmin Huo, Jianzhou Pang, Shuo Zhou

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Indicators of environmental variability in spring bread wheat cultivars under the conditions of Tyumen Province by V. V. Novokhatin, E. V. Zuev, Т. V. Shelomentseva, Т. A. Leonova

“…Accessions with low levels of plasticity and less pronounced environmental variability indices, but tolerant to deteriorated environmental conditions: ‘Tarskaya 10’ (k-64996), ‘FPCh-Рpd-0s’ (k-65123), and ‘Novosibirskaya 44’ (k-64867), can be used to produce climateresistant cultivars.Conclusion. …”
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Music and low-frequency vibrations for the treatment of chronic musculoskeletal pain in elderly: A pilot study. by Thom A H Eshuis, Peter J C Stuijt, Hans Timmerman, Peter Michael L Nielsen, André Paul Wolff, Remko Soer

“…<h4>Conclusions</h4>The combination of music and abdominally administered vibrations was found to be safe and well tolerated by the elderly patients. However, over time, neither the low-frequency treatment group nor the high-frequency treatment group provided clinically meaningful pain relief. …”
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Optimizing bioethanol production from sweet sorghum stem juice under very high gravity fermentation and temperature stress conditions by Phon Thatiyamanee, Pattana Laopaiboon, Lakkana Laopaiboon

“…The findings from this study, particularly the optimized fermentation conditions and stress tolerance strategies, could guide the scale-up to an industrial level of bioethanol production from sweet sorghum stem juice or other feedstocks using VHG fermentation, contributing to the development of more efficient and sustainable biofuel production processes.…”
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Exploring the Role of Social Workers in Addressing Health Disparities Among Maginalised Population in Kabale District. by Asasira, Precious

“…Based on the results from the study, 100% of the respondents agreed that there are some roles of Social Workers in addressing the health disparities among the marginalized population and these included social workers have a vital role in the need analysis, implementation and manage the project, social workers analyze the needs of the community with the help of community members and priorities they, the major role of the social worker in the community development begins with the organizing community on various social issues, social workers widen the betterment of individual, group, and community, social workers helps to improve tolerance among all and it leads into community development, social workers facilitate various benefits/projects provided by the government and NGOs. …”
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Successful Pregnancy Outcome in a Patient Treated with Pembrolizumab and Exposed to Fluoro-Deoxyglucose (¹⁸F-FDG) PET/CT: Case Report and Review of Literature by Anna Lucia Mastricci, Felice Sorrentino, Elisa Giansiracusa, Erika Zanzarelli, Graziana Silvana De Lucia, Vincenza Fernanda Fesce, Luigi Nappi, Lorenzo Vasciaveo

“…However, ICIs can impair immune tolerance, potentially increasing immune-related adverse events. …”
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Efficacy and Safety of Sacubitril/Valsartan Versus Amlodipine in Japanese Patients With Essential Hypertension: A Randomized, Multicenter, Open‐Label, Noninferiority Study (PARASOL... by Koichi Yamamoto, Daisuke Yarimizu, Ayano Shimanishi, Shunsuke Eguchi, Kazuma Iekushi, Yoichi Takami, Yoichi Nozato, Kazuomi Kario, Hiromi Rakugi

“…These results suggested that the blood pressure‐lowering effect of sacubitril/valsartan is comparable to that of amlodipine, with no marked differences in tolerability between the two groups. Sacubitril/valsartan, a potent antihypertensive drug comparable to amlodipine, is expected to improve blood pressure control in clinical practice.…”
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