Bazı Balık Türlerinde İz ve Toksik Metal Düzeylerinin Belirlenmesi ve İnsan Sağlığı Riskinin Değerlendirilmesi by Harun Çiftçi, Çiğdem Er Çalışkan, Kübra Öztürk

“…Çalışılan metaller için EWI değerlerinin Tolere Edilebilir Haftalık Alım Miktarları (PTWI) değerlerin-den düşük olduğu tespit edilmiştir. …”
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Validating the Hypoglycaemic and Hypotensive Roles of Salvia serotina (Chicken Weed) in Normal Healthy Sprague–Dawley Rats by Tameika Bartley, Paul Reese, Sophie Turfus, Ruby Alexander-Lindo

“…Aqueous, hexane, ethyl acetate, and methanol crude extracts of S. serotina L. were investigated for their anti-oxidant activities and hypoglycaemic and hypotensive effects in normal, healthy Sprague–Dawley rats using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, oral glucose tolerance test (OGTT), and the CODA noninvasive blood pressure system to determine systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), and heart rate (HR). …”
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The genomes of Scedosporium between environmental challenges and opportunism by Francesco Venice, Federica Spina, Domenico Davolos, Stefano Ghignone, Giovanna Cristina Varese

“…The genus Scedosporium (Microascaceae) includes fungi with high tolerance to environmental pollution, whilst some species can be considered major human pathogens, such as Scedosporium apiospermum and Scedosporium boydii. …”
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Influence of Dietary Chromium and Vitamin E Supplementation on Performance, Metabolism, and Physiology of Broilers Subjected to Cyclic Heat Stress by ML X Júnior, RD Bernardes, CH Oliveira, KMM Dias, BF Almeida, SO Borges, FS Dalólio, KM Gomes, CJ Rodrigues, AA Calderano

“…In conclusion, Cr and VitE, individually or combined, benefitted performance, glucose and thyroid hormone levels, immune and oxidative response, and heat stress tolerance.…”
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Efficacy and safety of camrelizumab combined with chemotherapy as second-line treatment for locally advanced, recurrent, or metastatic esophageal squamous cell carcinoma by Yinfang Gu, Xiaofang Zou, Junlin Zhu, Guowu Wu

“…Conclusion Second-line treatment with camrelizumab combined with chemotherapy is well-tolerated and associated with favorable oncological outcomes in patients with locally advanced, recurrent, or metastatic ESCC. …”
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The Validity Of 75gms OGTT For Detection Of GDM Keeping 100gms OGTT As Gold Standard by Shazia Mehreen, Muhammad Usman, Kashif Rauf, Saima Naz, Muhammad Abdul Rab Faisal Sultan, Muhammad Akram Randhawa

“… Objective: To determine the validity of 75gms (Oral Glucose Tolerance Test) OGTT for the detection of GDM keeping 100gms OGTT as the gold standard. …”
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Adaptation Strategies for Hemp in Alkaline Salt Environments: Fertilizer Management for Nutrient Uptake and Optimizing Growth by Yunshu Ye, Haoyu Wang, Panpan Zhang, Yuhong Zhang

“…This optimal combination maintains the K⁺/Na⁺ ratio in leaves above 1.2 and regulated Ca²⁺/Mg²⁺ homeostasis, maintaining a ratio of 2.8–3.2, indicating improved salt tolerance. Notably, excessive fertilizer applications (>400 mg·L⁻¹ total nutrients) exacerbated salt injury, reducing biomass accumulation by 25–30% and disrupting ion homeostasis. …”
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Characterization of Novel Nonobese Type 2 Diabetes Rat Model with Enlarged Kidneys by Ayaka Domon, Kentaro Katayama, Yuki Tochigi, Hiroetsu Suzuki

“…The cumulative incidence of DM in DEK males at the age of 30 weeks was 44.8%. Oral glucose tolerance tests showed glucose intolerance and decreased insulin secretion in response to glucose loading in affected males, features which were exacerbated with age. …”
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A Randomized Multicenter Study Comparing a Tacrolimus-Based Protocol with and without Steroids in HCV-Positive Liver Allograft Recipients by Ulf Neumann, Didier Samuel, Pavel Trunečka, Jean Gugenheim, Giorgio Enrico Gerunda, Styrbjörn Friman

“…Completion rates (45 versus 82%) indicated poorer tolerability with TAC/DAC than with TAC/STR. Steroid-free immunosuppression had no real impact on HCV viral load. …”
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Genome variability of domestic tomato varieties: data from AFLP analysis by A. V. Kulakova, E. A. Dyachenko, A. V. Shchennikova, O. N. Pyshnaya, E. A. Dzhos

“…Introgressive tomato breeding uses related wild Solanum species to improve cultivars for stress tolerance and fruit quality traits. The aim of this work was to evaluate the genome variability of 59 cultivars and perspective breeding lines of S. lycopersicum and 11 wild tomato species using the AFLP method. …”
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The role of climate change and niche shifts in divergent range dynamics of a sister-species pair by Summers, Jeremy, Lukas, Dieter, Logan, Corina J, Chen, Nancy

“…Species ranges are set by limitations in factors including climate tolerances, habitat use, and dispersal abilities. Understanding the factors governing species range dynamics remains a challenge that is ever more important in our rapidly changing world. …”
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Evaluating the Effect on Total Daily Insulin Dose in Adult Patients with Type 1 Diabetes Managed with Metformin and/or GLP-1 or GLP-1/GIP Receptor Agonists by Mayeesha Ahmed, Emily Pierson, Molly Webster

“…Data points were collected on starting dates of the first and second (if applicable) non-insulin agents, and the first office visit of at least 3 months on maximum tolerated doses. The primary endpoint was change in total daily insulin dose (TDD). …”
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Clinical Outcomes of Sequential Intrastromal Corneal Ring Segments and an Extended Range of Vision Intraocular Lens Implantation in Patients with Keratoconus and Cataract by C. Lisa, R. Zaldivar, A. Fernández-Vega Cueto, R. M. Sanchez-Avila, D. Madrid-Costa, J. F. Alfonso

“…In addition, this approach provides an increase of tolerance to defocus.…”
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DArTseq-based silicoDArT and SNP markers reveal the genetic diversity and population structure of Kenyan cashew (Anacardium occidentale L.) landraces. by Dennis Wamalabe Mukhebi, Pauline Wambui Gachanja, Diana Jepkoech Karan, Brenda Muthoni Kamau, Pauline Wangeci King'ori, Bicko Steve Juma, Wilton Mwema Mbinda

“…Understanding cashew genomics through the application of SilicoDArT and SNP markers is crucial for advancing cashew genomic breeding programs aimed at improving yield and nut quality, and enhancing resistance or tolerance to biotic and abiotic stresses. Our study presents an overview of the genetic diversity of cashew landraces in Kenya and demonstrates that DArT systems are a reliable tool for advancing genomic research in cashew breeding.…”
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NS5A replication complex inhibitor daclatasvir in the basis of chronic hepatitis C interferon-free therapy by M. V. Mayevskaya, M. S. Zharkova, V. T. Ivashkin

“…A safety profile and tolerability of daclatasvir is good, comparable to placebo group. …”
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Health Risk Assessment of Potentially Toxic Elements Contamination of Commonly Consumed Fruits in Bahir Dar Town, Northwest Ethiopia by Biset Asrade Mekonnen, Muluabay Getie Yizengaw, Haile Kassahun, Gebremariam Ketema

“…The ADI of potentially toxic elements was found to be lower than the maximum permitted tolerable daily intake in the studied fruits, and the HI values (mgday-1 kg-1) of all studied potentially toxic elements were lower than one in banana and orange, except mango (3.69). …”
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Discovery and Characterization of Novel Esterases with Ethyl Carbamate-Hydrolyzing Activity by LIU Qingtao, ZHU Sibao, WANG Tianwen, LI Chuang, QIAN Senhe, ZHANG Wenqing, CHENG Fan, TIAN Shufang

“…The EC-degrading esterases had good ethanol tolerance, which not only enrich the EC-hydrolyzing enzyme library, but also provide a new method for controlling the EC content in traditional fermented foods with low alcohol content.…”
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Safety of Levodopa-Carbidopa Intestinal Gel Treatment in Patients with Advanced Parkinson’s Disease Receiving ≥2000 mg Daily Dose of Levodopa by Cindy Zadikoff, Werner Poewe, James T. Boyd, Lars Bergmann, Horia Ijacu, Pavnit Kukreja, Weining Z. Robieson, Janet Benesh, Angelo Antonini

“…Patients who require ≥2000 mg/day LCIG exhibited a safety profile comparable to the established safety/tolerability of LCIG with similar clinical improvements. …”
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Short-Term Effects of a Novel Eye Mask Producing Heat and Vibration for the Treatment of Meibomian Gland Dysfunction: A Pilot Study by Luca Vigo, Marco Pellegrini, Francesco Carones, Vincenzo Scorcia, Giuseppe Giannaccare

“…This eye mask represents a novel well tolerated tool in the armamentarium of MGD treatments. …”
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Hybrid stochastic and robust optimization of a hybrid system with fuel cell for building electrification using an improved arithmetic optimization algorithm by Fude Duan, Mahdiyeh Eslami, Mustafa Okati, Dheyaa J. Jasim, Arsalan Khadim Mahmood

“…Furthermore, the hybrid UT-IGDT-RA outcomes found that the stochastic scenarios incorporated to simulate a range of uncertainties beyond the conventional IGDT-RA based-nominal scenario, and it provides a broader range of robust solutions, enabling operators to align strategies with their risk tolerance and improves system flexibility, and decision-making precision in the face of uncertainties.…”
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