Accumulation of cadmium and zinc in barley regenerants on a provocative soil background with cadmium by O. N. Shupletsova, E. V. Tovstik

“…An effective way to obtain barley (Hordeum vulgare L.) genotypes stress-tolerant to cadmium, with a low level of toxic ion accumulation in grain, is the selection of cells in selective in vitro systems, based on somaclonal variability, which promotes the formation of specific and nonspecific adaptive mechanisms.Materials and methods. …”
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Genome-wide identification and expression analysis of GRAS transcription factors under cold stress in diploid and triploid Eucalyptus by Jiannan Liu, Hao Chen, Chenhe Li, Kang Du, Jun Yang

“…Eucalyptus is an important fast-growing tree species worldwide, yet its poor cold tolerance limits its cultivation range. This study conducted a bioinformatics analysis of Eucalyptus grandis GRAS family and investigated the expression patterns of GRAS genes in different ploidy Eucalyptus under cold treatment. …”
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Characterisation of the Endophytic and Rhizospheric Bacillus licheniformis Strains Isolated from Sweet Potato with Plant Growth-Promoting and Yield Enhancing Potential by Ádám Bordé-Pavlicz, Anuar Rysbekovich Zhumakayev, Henrietta Allaga, Mónika Vörös, Pramod Wasudeo Ramteke, Tamás Monostori, Csaba Vágvölgyi

“…Experiments have been conducted to investigate the tolerance of selected strains to different limiting factors such as pH, temperature, and water activity, which affect survivability in various agricultural environments. …”
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Vascular Endhothelial Growth Factor levels in medium-intensity versus low-intensity exercise with blood flow restriction in elderly women by Nanda Aulya Ramadhan, Damayanti Tinduh, Nuniek Nugraheni, Imam Subadi, Inggar Narasinta, Soenarnatalina Melaniani

“…Elderly people have many limitations in strengthening exercises for increasing muscle mass, especially in safety and tolerance. Low-intensity strengthening exercise combined with blood flow restriction can be an alternative to increase muscle strength to the same extent as high-intensity strengthening exercise. …”
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Modeling performances of maize cultivars under current and future climate scenarios in southern central Ethiopian rift valley by Daniel Markos, Walelign Worku, Girma Mamo

“…Conclusions There is critical need for reduction of GHGs emissions, generation of innovative adaptation strategies, and development of drought and heat stress tolerant maize cultivars. Hence, researchers and policy makers shall act with utmost urgency to embark with breeding programs that target climate change adaptation traits in maize crop.…”
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Leveraging mRNA technology for antigen based immuno-oncology therapies by Wei Zheng, Michele Ceccarelli, Charalampos S Floudas, Siranush Sarkizova

“…Tumor neoantigens are de novo epitopes derived from somatic mutations, avoiding T-cell central tolerance of self-epitopes and inducing immune responses to tumors. …”
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Prevalence and Management of Hypokalemia in Peritoneal Dialysis Patients in Qatar by Abdullah Hamad, Mohammed Ezzat Hussain, Shaza Elsanousi, Hanaa Ahmed, Luzvi Navalta, Vimala Lonappan, Fadwa Alali

“…Treatment usually includes oral potassium supplements, which are poorly tolerated. Our aim was to evaluate the prevalence of hypokalemia in PD patients in Qatar and to improve treatment measures. …”
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GWAS of a soybean breeding collection from South East and South Kazakhstan for resistance to fungal diseases by A. Zatybekov, S. Abugalieva, S. Didorenko, A. Rsaliyev, Y. Turuspekov

“…Modern genomic studies can be applied to facilitate efficient breeding research for improvement of soybean fungal disease tolerance. Therefore, the objective of this genome-wide association study (GWAS) was analysis of a soybean collection consisting of 182 accessions in relation to fungal diseases in the conditions of South East and South Kazakh­stan. …”
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Design and Fabrication of a Car Sports Rims. by Nsimbe Laban

“…A permanent mould is however recommended for this study so as to give a better surface finish and better dimensional tolerance. Low pressure casting is recommended that is by filling the mould cavity from the bottom so as to prevent the risk of air bubbles entering into the mould cavity hence minimizing casting defects. …”
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Farmers’ climate change perception, impacts and adaptation strategies in response to drought in the Northwest area of Bangladesh by J.M. Adeeb Salman Chowdhury, Md. Abdul Khalek, Md. Kamruzzaman

“…The most significant adaptation strategies adopted by the farmers were irrigation facilities, agronomic management, drought-tolerant rice varieties, adopting new technologies, and alternative enterprises of land use change. …”
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Spontaneous anastomosis of esophageal atresia without esophageal stricture formation: A case report by S. Tan Tanny, S.E. Newman, M. Safe, W.J. Teague

“…At the age of 4.5 years, the patient is tolerating an unrestricted diet and has a growth curve that matches the curve of his twin sibling. …”
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Ultrathin skin-conformable electrodes with high water vapor permeability and stretchability characteristics composed of single-walled carbon nanotube networks assembled on elastome... by Tatsuhiro Horii, Kai Yamashita, Marimo Ito, Kei Okada, Toshinori Fujie

“…The SWCNT 3rd-SBS nanosheets attached to model skin show high tolerances to bending and artificial sweat at different pH values (i.e., the electrical resistance changes ~1.1 times). …”
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Effect of ON and OFF Axis Open Hole Tensile Testing of GFRP/Epoxy Composites by Sunith Babu Loganathan, Ashok Kumar Krishnappa, Jaya Christiyan Kumaravelu Grace Jesu Bai, Ritin Pavirala, Rajesh Mathivanan

“…Further, the damage tolerance in OFF-axis samples was higher as compared to ON-axis specimens.…”
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Comparative miRNAome combined with transcriptome and degradome analysis reveals a novel miRNA-mRNA regulatory network associated with starch metabolism affecting pre-harvest sprout... by Longqing Sun, Ting Zhao, Dandan Qin, Jing Dong, Daorong Zhang, Xifeng Ren

“…Results This study compared the differences of germinated seeds in miRNAome between the PHS-tolerant and PHS-susceptible white wheat varieties. …”
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Integrating MAPK pathway inhibition into standard-of-care therapy for pediatric low-grade glioma by Erin E. Crotty, Aimee A. Sato, Aimee A. Sato, Mohamed S. Abdelbaki

“…Inhibitors of the MAPK pathway, primarily MEK and RAF kinase inhibitors, have emerged as effective and tolerable second-line or later therapy for pLGG. As familiarity with these targeted agents increases, their indications for use continue to expand and Phase 3 clinical trials investigating their utility in the front-line setting are ongoing. …”
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<i>Agrobacterium rhizogenes</i>-Mediated Hairy Root Transformation in <i>Rosa</i> by Jun Lu, Yuwen Huang, Yuhan Guo, Chunguo Fan, Guozhen Yuan, Rui Zhou, Jingjing Sun, Mengjuan Bai, Kun Wang, Jinyi Liu, Changquan Wang

“…Improving ornamental qualities (color, aroma, flower shape, plant architecture, petal senescence), agronomic traits (disease resistance, stress tolerance), and other traits would add value to cultivated roses. …”
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Genetic Variations in the Kir6.2 Subunit (KCNJ11) of Pancreatic ATP-Sensitive Potassium Channel Gene Are Associated with Insulin Response to Glucose Loading and Early Onset of Type... by Yi-Der Jiang, Lee-Ming Chuang, Dee Pei, Yann-Jinn Lee, Jun-Nan Wei, Fung-Chang Sung, Tien-Jyun Chang

“…Furthermore, in normal glucose-tolerant children/adolescents, K23 allele carriers had a higher insulin response to oral glucose loading.…”
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Ranibizumab for Visual Impairment due to Diabetic Macular Edema: Real-World Evidence in the Italian Population (PRIDE Study) by Ugo Menchini, Francesco Bandello, Vincenzo De Angelis, Federico Ricci, Luigi Bonavia, Francesco Viola, Elisa Muscianisi, Massimo Nicolò

“…Ranibizumab was well-tolerated and improved/maintained VA in 40.2%–68.8% patients, with no differences in case of unilateral or bilateral pathology. …”
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High lipid diet can keep liver health but cause muscle oxidative stress of triploid rainbow trout treated with acute hypoxic challenge by Changye Li, Buying Han, Guoliang Sun, Haining Tian, Zezhong Wu, Changzhong Li, Yuqiong Meng, Rui Ma

“…In the study, two isonitrogenous diets with a lipid level of 23 % (normal control, NC) and 30 % (high lipid, HL), respectively, were fed to triploid rainbow trout with initial average weight of 233 g for 80 days, and then subjected to an acute hypoxic challenge, and estimated the effect of HL diet on acute hypoxic tolerance of triploid rainbow trout. The results showed that 1) HL diet significantly increased plasma lactate dehydrogenase, glucose, total cholesterol, high and low density lipoprotein cholesterol levels, but decreased alanine aminotransferase level (P < 0.05). 2) HL diet did not affect hepatic malondialdehyde (MDA) content (P > 0.05), while it significantly increased MDA content in the plasma and muscle (P < 0.05). …”
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The anti-PD-L1/CTLA-4 bispecific antibody KN046 plus lenvatinib in advanced unresectable or metastatic hepatocellular carcinoma: a phase II trial by Da Xu, Hongwei Wang, Quan Bao, Kemin Jin, Ming Liu, Wei Liu, Xiaoluan Yan, Lijun Wang, Yanqiao Zhang, Guangyu Wang, Yue Ma, Zhigang Ma, Chunhui Zhang, Jiebing Tang, Sha Wang, Jiaohui Pang, Ting Xu, Kun Wang, Baocai Xing

“…The primary endpoints were safety, tolerability, dose-limiting toxicity (DLT), and objective response rate (ORR) according to RECIST v1.1. …”
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