Safety and Efficacy of Everolimus Plus Exemestane in Postmenopausal Women with Treatment-refractory Hormone Receptor-positive, Human Epidermal Growth Factor Receptor 2-negative Adv... by Yuan-Ching Chang, Kun-Ming Rau, Dar-Ren Chen, Tsu-Yi Chao, Ming-Feng Hou, Chiun-Sheng Huang*

“…Materials and Methods: The primary objective was to evaluate the safety and tolerability of everolimus and exemestane (EVE + EXE); the secondary endpoints included progression-free survival (PFS), response rates, and clinical benefit rate. …”
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Electro-Oxidation of Glycerol on Core–Shell M@Pt/C (M = Co, Ni, Sn) Catalysts in Alkaline Medium by Rudyere Nascimento Silva, Leandro Aparecido Pocrifka, Ermete Antolini, Raimundo Ribeiro Passos

“…Furthermore, Sn@Pt/C displayed remarkable poisoning tolerance attributed to a combined effect: a bifunctional mechanism driven by Sn oxides and an electronic effect within the PtSn alloy. …”
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The “guild” concept in riparian ecology: Use, limitations and prospects for improving the reproducibility and transferability of results by Philippe Janssen

“…Most of these traits, however, were common to no more than three studies, and most studies mixed traits related to plant morphology with ecological “traits” describing abiotic tolerance of species, obtained without replicable protocols. …”
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Efficacy of Single-Pill Combination of Telmisartan 80 mg and Hydrochlorothiazide 25 mg in Patients with Cardiovascular Disease Risk Factors: A Prospective Subgroup Analysis of a Ra... by Harold Bays, Pingjin Gao, Birgit Völker, Michaela Mattheus, Luis M. Ruilope, Dingliang Zhu

“…Antihypertensive treatment with T80/H25 single-pill combination is effective and generally well tolerated, irrespective of the presence of CVD risk factors.…”
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Structure, Immune and Anti-aging Activities of Capsular Polysaccharide Produced by Lactobacillus plantarum W1 by Yongjiao GAO, Kun WANG, Jing ZHAO, Feng ZUO

“…Concurrently, CPS significantly enhanced the antioxidant system of C. elegans (P<0.05), prolonged their lifespan, and improved their stress tolerance. The average lifespan of nematodes under normal, oxidative stress and heat shock conditions reached its maximum at 125 μg/mL, with lifespan extension rates of 21.05%±0.21%, 42.86%±0.27% and 50.00%±0.27%, respectively. …”
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Duodenal Eosinophilia in Functional Dyspepsia by A. S. Silaeva, E. L. Bueverova, Yu. O. Shulpekova

“…The patient noted poor tolerance to canned and fermented foods, which provoked an increase in dyspepsia and sometimes caused watery diarrhea. …”
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Identification of novel RIPK4 variants in a Chinese patient with Arthrogryposis Multiplex Congenita (AMC) by Yi-Lei Lu, Meng-wei Liu, Jie-Yuan Jin, Ding Pan

“…The pathogenic mechanisms of the identified variations were analyzed using protein tolerance profiling and modeling. Results We identified two novel RIPK4 variants (c.1354G > A, p.E452K; c.1558A > T, p.T520S). …”
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Serum Glucose-Dependent Insulinotropic Polypeptide (GIP) and Glucagon-Like Peptide-1 (GLP-1) in association with the Risk of Gestational Diabetes: A Prospective Case-Control Study by Maryam Mosavat, Siti Zawiah Omar, Sajad Jamalpour, Peng Chiong Tan

“…Methods. 53 women with GDM (30 managed with diet only (GDM-diet) and 23 treated with insulin (GDM-insulin)) and 43 pregnant women with normal glucose tolerance (NGDM) were studied, with GIP and GLP-1 levels measured at 24–28 weeks (E1), prior (E2) and after (E3) delivery, and postpuerperium (E4). …”
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Impact of BN and WC Particulate Reinforcements on Mechanical Properties and Damage Development of Al-2048 Metal Matrix Composites by T. Sivakumar, Chikkappa Udagani, M. Sivaranjani, M. Sudhakar, Reem Mohammed Alharbi, Neveen Abdel-Raouf, Ibraheem Borie M. Ibraheem, Essam Nageh Sholkamy, Mahadeo A. Mahadik, Simon Yishak

“…The fraction of broken particles in the 20v% WC/Al-2048 composite as a function of strain is much higher than that in the 15v% BN/Al-2048 composite. Because of their tolerance for substantial strain at the interface, maximum K1c, and moderate thermal extension, BN elements can share a lot of loads and provide more excellent reinforcement than WC particles in terms of composite strength and flexibility.…”
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Longitudinal Relationship between the Introduction of Medicinal Cannabis and Polypharmacy: An Australian Real-World Evidence Study by Maja Kalaba, Graham M. L. Eglit, Matthew T. Feldner, Patrizia D. Washer, Tracie Ernenwein, Alistair W. Vickery, Mark A. Ware

“…Though observational in nature, these findings suggest MC is generally well-tolerated, consistent with the previous literature, and may reduce concomitant use of some medications. …”
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Stress resistance in barley cultivars of various agroecological origin under extreme continental climate conditions by O. A. Yusova, P. N. Nikolaev, Ya. B. Bendina, I. V. Safonova, N. I. Aniskov

“…The research targets were 24 barley cultivars representing various breeding centers and tolerance regions of Russia. The cultivar ‘Omsky 91’ developed at Omsk Agrarian Scientific Center was used as the reference.Results and discussion. …”
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Thinning enhances whitebark pine (Pinus albicaulis) growth and resin duct defenses by Nickolas E. Kichas, Erin K. Shanahan, Sharon M. Hood

“…Our study investigated the response of whitebark pine tree growth and resin duct defenses to thinning and removal of competing shade‐tolerant conifers in the Caribou‐Targhee National Forest, Idaho, USA. …”
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Selenium nanoparticles enhance metabolic and nutritional profile in Phaseolus vulgaris: comparative metabolomic and pathway analysis with selenium selenate by Asmaa Abdelsalam, Fatma Abd El Lateef Gharib, Arezue Boroujerdi, Nada Abouelhamd, Eman Zakaria Ahmed

“…Abstract Selenium is a beneficial element in agriculture, particularly for its potential to improve plant growth and stress tolerance at suitable concentrations. In this study, Phaseolus vulgaris was foliar-sprayed with selenium selenate (Se) or selenium nanoparticles (SeNP) at different concentrations during the vegetative stage; afterward, the seed yield was analyzed for metabolomics using 1H, J-resolved and HSQC NMR data, and NMR databases. …”
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Swiss Сonfedеration experience on reception of migrants by N. A. Voronina

“…There is a developed and scientifically grounded system of reception, accommodation and integration of foreigners and asylum seekers in Switzerland, which is based on constitutional values, respect and mutual tolerance. At the core of this system is a general strategy of integration, which constitutes a country’s core policy of integration and covers various areas: law, politics, labour issues, housing, education, culture and religion. …”
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The genomes of the most diverse AA genome rice species provide a resource for rice improvement and studies of rice evolution and domestication by Muhammad Abdullah, Agnelo Furtado, Ardashir Kharabian Masouleh, Pauline Okemo, Robert Henry

“…Both wild species uniquely shared some genes with domesticated rice many of which were associated with disease resistance and stress tolerance. Structural differences included the large 6 Mb inversion on chromosome 6 specific to Japonica rice. …”
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Optimal Hemoglobin A1c Levels for Screening of Diabetes and Prediabetes in the Japanese Population by Masanori Shimodaira, Shinji Okaniwa, Norinao Hanyu, Tomohiro Nakayama

“…A 75 g oral glucose tolerance test (OGTT) was used to diagnose diabetes and prediabetes. …”
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Institutional Incidence of Severe tPA-Induced Angioedema in Ischemic Cerebral Vascular Accidents by Matthew Sczepanski, Paul Bozyk

“…Tissue plasminogen activator (tPA) is commonly used in ischemic cerebral vascular accidents (CVAs). tPA is generally well tolerated; however, orolingual angioedema is a well-documented adverse effect. …”
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Analysis the Spatial Dynamics of Aloe Vera Medicinal Plants in Climate Change condition. Case: Hormozgan Province by Shahrbanoo Ghanbari Adivi, Morteza Khodagholi, Amir Gandomkar

“…These areas are generally consistent with the lowlands of the southern sections of the southern province and are consistent with the soils with tissue and depth and drainage, namely, the arid soils of Sevil and anti-Seville, while in the northern parts of the province, the supply factor, supply The need for an aloe vera plant, tolerance in the year and nightly, the product performance is very weak and the development of aloe vera farms in these areas is not recommended. …”
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Performance optimization of sorption-enhanced DME synthesis (SEDMES) from captured CO2 and renewable hydrogen by I. Tyraskis, A. Capa, G. Skorikova, S. N. Sluijter, J. Boon

“…The SEDMES process proved to be tolerant to high concentrations of inert gases such as N2, reducing the need for extensive pretreatment steps. …”
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Effect of NaCI solution concentration, particle size and ratio on viscosity inhibitor of porang flour by Mohammad Amirul Muzakki, Erliza Noor, Anto Tri Sugiarto

“…The residual calcium oxalate in porang flour contradicted the standard for human body tolerance, explicitly 71 mg/100g. Therefore, the resultant flour is not safe to consume. …”
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