Serum Concentrations of Betatrophin and Its Association with Indirect Indices of Insulin Resistance and Beta Cell Function in Women with Polycystic Ovary Syndrome by Agnieszka Adamska, Agnieszka Łebkowska, Małgorzata Jacewicz, Anna Krentowska, Justyna Hryniewicka, Sławomir Wołczyński, Maria Górska, Irina Kowalska

“…Insulin secretion was evaluated with HOMA-B. An oral glucose tolerance test (OGTT) with estimation of serum betatrophin concentrations was performed. …”
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The First Saint Petersburg Regional Inflammatory Bowel Diseases Registry on the Basis of the Regional Health Information System: Principles of Functioning, Testing Results, Plan of... by Yu. P. Uspenskiy, A. M. Sarana, L. N. Melentyeva, A. V. Yazenok, S. V. Petrov, Yu. A. Fominykh, S. V. Ivanov, A. V. Shotik, A. M. Segal, T. V. Gorbacheva, S. D. Plotnikova, K. V. Dronov

“…The functioning of the Saint Petersburg IBD Registry allows to achieve following primary goals within region: assessment of the epidemiological features of IBD in Saint Petersburg; dynamic assessment of the disease features; assessment and planning of health care resources required to provide care to IBD patients; improvement of approaches to the treatment taking into account the specifics of the region; assessment of the effectiveness and tolerability of specific treatment including biologics.…”
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Alleviating effects and mechanisms of action of large-leaf yellow tea drinking on diabetes and diabetic nephropathy in mice by Guangshan Zhao, Jianyuan Teng, Ruixia Dong, Qiuyan Ban, Lian Yang, Kang Du, Yifei Wang, Hanlin Pu, Chung S. Yang, Zhe Ren

“…Results showed that LYT infusions (1/100 and 1/50, m/V) as drinking fluid for 4 weeks reduced diabetic polydipsia and polyuria, enhanced glucose tolerance and insulin sensitivity, and lowered fasting blood glucose level. …”
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The Hidden Influence and Catalysts of Religious and Moral Education in Ghanaian Basic Schools: Co-Curricular Activities in Perspective by Dennis Tawiah, John Kwaku Opoku, Peter Addai-Mensah

“…The study highlights the benefits of co-curricular activities, including the development of empathy, tolerance, leadership skills, and ethical decision-making. …”
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HLA-G Expression on Blasts and Tolerogenic Cells in Patients Affected by Acute Myeloid Leukemia by Grazia Locafaro, Giada Amodio, Daniela Tomasoni, Cristina Tresoldi, Fabio Ciceri, Silvia Gregori

“…DC-10 are present in the peripheral blood and are essential in promoting and maintaining tolerance via the induction of adaptive T regulatory (Treg) cells. …”
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Evaluating the antagonist effect of naltrexone implant via opioid challenge tests with escalating doses of hydromorphone injection in former heroin dependent patients by Wei Qu, Xuyi Wang, Chongyang Dong, Tao Zhang, Shugui Yin, Zhijun Sun, Shiqiang Wang, Anni Guo, Wei Hao

“…Pharmacokinetic data suggested that effective plasma naltrexone concentration (≥1ng/ml) was detected from the third day for over 148 days, with higher concentration and longer duration in the 1.5 g group. All subjects tolerated NTX-IMP well. The findings indicate that the NXT-IMP effectively blocks the agonistic effects of hydromorphone in a dose-dependent manner.…”
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Attitudes and adherence to changes in nutrition and physical activity following surgery for prostate cancer: a qualitative study by Richard M Martin, Raj Persad, J Athene Lane, Ellie Shingler, Luke A Robles, Edward Rowe, Anthony Koupparis, Amit Bahl, Constance Shiridzinomwa, Lucy McGeagh

“…Men identified several barriers and facilitators to performing these new behaviours. Barriers included tolerance to dietary changes, PA limitations and external obstacles. …”
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Thermosensitive In Situ Ophthalmic Gel for Effective Local Delivery and Antifungal Activity of Ketoconazole Nanoparticles by Chutima Chaiwut, Sarin Tadtong, Puriputt Akachaipaibul, Jutamas Jiaranaikulwanitch, Sudarshan Singh, Siriporn Okonogi, Dwi Marlina Syukri, Chuda Chittasupho

“…The in situ gel showed sustained release, effective antifungal activity against <i>Malassezia furfur</i>, and good tolerability, suggesting it as a promising alternative for treating fungal keratitis with improved bioavailability and patient compliance.…”
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Moderate Weight Reduction in an Outpatient Obesity Intervention Program Significantly Reduces Insulin Resistance and Risk Factors for Cardiovascular Disease in Severely Obese Adole... by J. Grulich-Henn, S. Lichtenstein, F. Hörster, G. F. Hoffmann, P. P. Nawroth, A. Hamann

“…Metabolic parameters were measured in the fasting state, insulin resistance was evaluated in an oral glucose tolerance test. Results. Mean standard deviation score of the body mass index (SDS-BMI) in the study group dropped significantly from +2.5 ± 0.5 to 2.3 ± 0.6 (P<0.0001) after participation in the program. …”
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Differentiated effects and mechanisms of N-, P-, S-, and Fe-modified biochar materials for remediating Cd- and Pb-contaminated calcareous soil by Amir Bostani, Xingying Meng, Le Jiao, Srđan D. Rončević, Peng Zhang, Hongwen Sun

“…Additionally, PBC promoted the growth, enzyme activity, and tolerance to Cd- and Pb-contaminated soil of Chinese cabbage. …”
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Effectiveness of positive allosteric modulators of metabotropic glutamate receptor 2/3 (mGluR2/3) in animal models of schizophrenia by David Olivares-Berjaga, Albert Martínez-Pinteño, Natalia Rodríguez, Sergi Mas, Constanza Morén, Eduard Parellada, Patricia Gassó

“…One of these new therapies involves the positive allosteric modulators (PAMs) of metabotropic glutamate receptors, mainly types 2/3 (mGluR2/3). mGluR2/3 PAMs are selective for the receptor, present high tolerability and can modulate the activity of the receptor for long periods. …”
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Water Quality Assessment of Selected Wells in the Farmer-led Irrigation System in Anloga District, Volta Region, Ghana by Henry Evonameh Igbadun, Olufunke Cofie, Donatus Obiajulu ONWUEGBUNAM, Michael Adote Kpakpo-Sraha, Seifu TILAHUN

“…These wells are prone to salinity, and farmers’ discretion is recommended through the adoption of conditional use of the irrigation water such as growing of salt-tolerant crops. …”
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Electroconvulsive Therapy in a Renal Transplantation Patient: A Rare Combination of Disease and Treatment by Giovanni Malaty, Kerilyn Godbe, Mehdi Elmouchtari, Gurjot Malhi, Justin White, Azziza Bankole, Tracey Criss

“…Electroconvulsive therapy was subsequently initiated and was well-tolerated. Treatments progressively alleviated his depressive and psychotic symptoms and did not adversely affect the function of his transplanted kidney, which was closely monitored throughout the treatment process. …”
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Virtual reality support during systemic cancer therapy to improve anxiety/depressive symptoms and reduce toxicity in patients with gastrointestinal cancers—OncoVR by S. Kasper, S. Liszio, K. Schorrmann, M. Gerigk, S. Jovic, O. Basu, K. Kostbade, B. Goraus, A. Elsakka, B. Puladi, J. Kleesiek, M. Schuler, G. Luijten, J. Egger

“…Primary endpoints are the feasibility of VR support (80% of the patients can tolerate its use for a minimum duration of 20 min), and changes in anxiety/depressive symptoms using the Hospital Anxiety and Depression Scale (HADS-D) and Positive and Negative Affect Schedule (PANAS) questionnaires. …”
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Improving Storability of “Nanfeng” Mandarins by Treating with Postharvest Hot Water Dipping by İbrahim Kahramanoğlu, Chuying Chen, Yao Chen, Jinyin Chen, Zengyu Gan, Chunpeng Wan

“…Furthermore, HWD treatment significantly enhanced the activities of SOD, POD, and PPO which are known to enhance tolerance to lipid peroxidation and are associated with the fruit protection from injuries and pathogens. …”
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Temozolomide as Second or Third Line Treatment of Patients with Neuroendocrine Carcinomas by Ingrid H. Olsen, Jens B. Sørensen, Birgitte Federspiel, Andreas Kjaer, Carsten P. Hansen, Ulrich Knigge, Seppo W. Langer

“…The treatment was well tolerated. Conclusion. Temozolomide monotherapy has limited effect in treatment of recurrent neuroendocrine carcinomas. …”
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Intravenous esketamine in pediatric Rett syndrome: An open-label, early phase 1 pilot study by Huiping Li, Shu Liu, Caimei Lin, Yuchao Wu, Xiuping Wu, Yukun Huang, Yajun Wu, Xiubin Tong, Xiu Xu

“…The treatment with intravenous esketamine was generally well tolerated and safe, with some patients experiencing mild AEs, including self-alleviating nausea, vomiting, and irritability. …”
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Impacts of Land Use on Soil Erosion: RUSLE Analysis in a Sub-Basin of the Peruvian Amazon (2016–2022) by Moises Ascencio-Sanchez, Cesar Padilla-Castro, Christian Riveros-Lizana, Rosa María Hermoza-Espezúa, Dayan Atalluz-Ganoza, Richard Solórzano-Acosta

“…In addition, 7.65% of the study area (74.52 km²) exceeds the soil loss tolerance limit (15 t ha⁻¹ year⁻¹). …”
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Characterization of the Collagen Extraction Manufacturing Process Using Markov Chains and Artificial Neural Networks by Rosa Trasvina-Osorio, Sergio Alonso-Romero, Juan de Anda-Suarez, Valentin Calzada-Ledesma, Javier Yanez-Mendiola, Luis Fernando Villanueva-Jimenez, Erick Rojas-Mancera

“…The proposed tool obtains a minimum adjustment with a deviation whose tolerance is valid for predicting the collagen extraction yield. …”
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Circulating Levels of Betatrophin and Irisin Are Not Associated with Pancreatic β-Cell Function in Previously Diagnosed Type 2 Diabetes Mellitus Patients by Lingshu Wang, Jun Song, Chuan Wang, Peng Lin, Kai Liang, Yu Sun, Tianyi He, Wenjuan Li, Ruxing Zhao, Jun Qin, Yiran Lu, Jinbo Liu, Fuqiang Liu, Xinguo Hou, Li Chen

“…In total, 20 age-, sex-, and body mass index- (BMI-) matched normal glucose tolerance (NGT) subjects and 120 previously diagnosed T2DM patients were included in this study. …”
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