Total Body Irradiation without Chemotherapy as Conditioning for an Allogeneic Hematopoietic Cell Transplantation for Adult Acute Myeloid Leukemia by Sultan Altouri, Mitchell Sabloff, David Allan, Harry Atkins, Lothar Huebsch, Dawn Maze, Rajiv Samant, Christopher Bredeson

“…Two patients remain in remission beyond day 1500. 16 Gy TBI followed by an alloHCT for AML, failing induction, is feasible and tolerable.…”
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Current Control in Field-Excited Flux Switching Machines: No-Load Induced Voltage Impact Based on the Winding Connection by Diogo P. V. Galo, Thales A. C. Maia, Braz de J. Cardoso Filho

“…Doubly salient reluctance machines exhibit a simple structure, robust mechanical strength, excellent fault tolerance, and a wide range of speed regulation, which makes them suitable for in-wheel applications. …”
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Metabolic enzyme inhibitory abilities, in vivo hypoglycemic ability of palmleaf raspberry fruits extracts and identification of hypoglycemic compounds by Jun Tan, Danshu Wang, Yu Lu, Yehan Wang, Zongcai Tu, Tao Yuan, Lu Zhang

“…The 40 % ethanol eluting fraction of 40EUS showed the strongest a-glucosidase inhibition with the IC50 value of 37.79 ng/mL, it could also effectively attenuate the fasting blood glucose level and oral glucose tolerance of C57BL/6 mice. Twenty-six compounds were identified from 40 % ethanol fraction by using HPLC-QTOF-MS/MS, hydrolysable tannins (including 11 ellagitannins and 4 gallotannins) were the major compounds, phenolic acids came to the second. …”
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Comparative Study of Antioxidant Status in Androgenic Embryos of Aesculus hippocastanum and Aesculus flava by Dubravka Štajner, Boris M. Popović, Dušica Ćalić, Marijana Štajner

“…However, the leaves of A. flava showed higher antioxidant activity than the leaves of A. hippocastanum, and therefore they have a stronger tolerance of oxidative stress. Androgenic embryos of both species had low amount of antioxidants due to controlled in vitro environmental conditions (T, photoperiod, humidity, nutritive factors, and pathogen-free). …”
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Pelvic Radiation Disease Management by Hyperbaric Oxygen Therapy: Prospective Study of 44 Patients by Mehdi Ouaïssi, Stephanie Tran, Diane Mege, Vivien Latrasse, Alain Barthelemy, Nicolas Pirro, Philippe Grandval, James Lassey, Igor Sielezneff, Bernard Sastre, Mathieu Coulange

“…HBOT was generally well tolerated. Only one patient stopped precociously due to transient myopia. …”
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Bird Utilisation of Vertical Space in Urban Environments by Annalise J. Re, Andrew M. Rogers, Hugh P. Possingham, Salit Kark

“…Grouping species by urban tolerance (i.e., whether an urban avoider, adapter, or exploiter) and foraging level helped explain why some species could utilise certain height profiles across the urban structural gradient where others could not. …”
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HISTORY AND RESULTS OF THE INTRODUCTION OF PALMS (ARECACEAE C.H. SCHULTZ) ON THE SOUTHERN COAST OF THE CRIMEA by A. P. Maksimov, Yu. V. Plugata, V. P. Koba, A. F. Khromov

“…A  picture of actual damages of various palm species during severe  winters has been shown, and the degree of their tolerance to  extreme negative temperatures determined. …”
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The Chloroplastic Small Heat Shock Protein Gene KvHSP26 Is Induced by Various Abiotic Stresses in Kosteletzkya virginica by Xiaohua Liu, Lizi Zhao, Jianzhao Li, Lijun Duan, Kai Zhang, Xuqiang Qiao, Weihuan Li, Chengchao Zheng, Xiaoli Tang, Hongxia Zhang

“…All these results suggest that KvHSP26 encodes a new sHSP, which is involved in multiple abiotic stress responses in K. virginica, and it has a great potential to be used as a candidate gene for the breeding of plants with improved tolerances to various abiotic stresses.…”
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Expanded Use of Vorasidenib in Non-Enhancing Recurrent CNS WHO Grade 3 Oligodendroglioma by Alexander S. Himstead, Jefferson W. Chen, Eleanor Chu, Mari A. Perez-Rosendahl, Michelle Zheng, Sherin Mathew, Carlen A. Yuen

“…Vorasidenib was well tolerated in our patient with a mild elevation in his liver transaminases that resolved following a brief interruption in treatment. …”
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Robust parameter design for constrained randomization lifetime improvement experiments by Shanshan Lv, Yichen Zhao, Sen Li, Guodong Wang, Xueqing Wang

“…Finally, we discuss the practical implications of the optimal solutions for manufacturers, finding that variations remain tolerable within a certain range.…”
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Drug-Drug Interactions Between HIV Antivirals and Concomitant Drugs in HIV Patients: What We Know and What We Need to Know by Emanuela De Bellis, Danilo Donnarumma, Adele Zarrella, Salvatore Maria Mazzeo, Annarita Pagano, Valentina Manzo, Ines Mazza, Francesco Sabbatino, Graziamaria Corbi, Pasquale Pagliano, Amelia Filippelli, Valeria Conti

“…Several studies have examined the pharmacokinetics and tolerability of different drug combinations. Protease inhibitors, followed by nonnucleoside reverse transcriptase inhibitors and integrase inhibitors have been recognized as the main players in DDIs with antivirals used to control co-infection, such as Hepatitis C virus, or with drugs commonly used to treat HIV comorbidities, such as lipid-lowering agents, proton pump inhibitors and anticancer drugs. …”
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Exploring the intricacies of plant growth promoting rhizobacteria interactions: an omics review by Kamogelo Mmotla, Nompumelelo R. Sibanyoni, Farhahna Allie, Lungile Sitole, Thendo Mafuna, Manamele D. Mashabela, Msizi I. Mhlongo

“…PGPR play a role in stimulating plant growth and development and enhancing plant resistance and tolerance to biotic and abiotic stresses. To effectively fulfil their roles, PGPR engage in intricate interactions with one another, a phenomenon that occurs within the rhizosphere. …”
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Environmental DNA Reveals Habitat Variables Driving Platypus (Ornithorhynchus anatinus) Distribution Across an Urbanised Landscape by Tamielle Brunt, Matt Cecil, Josh Griffiths, Christine Adams‐Hosking, Peter J. Murray, Annabel L. Smith

“…These findings reflect important waterway connectivity and food resources for platypus, highlighting relationships between platypus, their environment and their tolerance to urban stream threats. For example, platypuses are unlikely to occur in streams where water availability is reduced, and movement will be limited in shallow, dry streams. …”
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Mobilization of Stem Cells Using G-CSF for Acute Ischemic Stroke: A Randomized Controlled, Pilot Study by Kameshwar Prasad, Amit Kumar, Jitendra Kumar Sahu, M. V. P. Srivastava, Sujata Mohanty, Rohit Bhatia, Shailesh B. Gaikwad, Achal Srivastava, Vinay Goyal, Manjari Tripathi, Chandrashekar Bal, Nalini Kant Mishra

“…Although this study did not have power to examine efficacy, it provides preliminary evidence of potential safety, feasibility, and tolerability of G-CSF therapy. Further studies need to be done on a large sample to confirm the results.…”
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Fenofibrate Enhances the In Vitro Differentiation of Foxp3+ Regulatory T Cells in Mice by Zhou Zhou, Ying Liang, Yanxiang Gao, Wei Kong, Juan Feng, Xian Wang

“…Foxp3+ regulatory T cells (Tregs) play a critical role in maintaining immune self-tolerance. Reduced number and activity of Tregs are usually found in autoimmune and inflammatory diseases, and enhancing the differentiation of Tregs may be a promising therapeutic strategy. …”
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Lipidomic Signature of Pregnant and Postpartum Females by Longitudinal and Transversal Evaluation: Putative Biomarkers Determined by UHPLC-QTOF-ESI⁺-MS by Alexandra Traila, Marius Craina, Carmen Socaciu, Andreea Iulia Socaciu, Diana Nitusca, Catalin Marian

“…These adaptations impact various systems, including immune tolerance, metabolism, and endocrine function. While metabolomics has been utilized to study pregnancy-related metabolic changes, comprehensive comparisons between pregnant and non-pregnant states, particularly using ultra-high-performance liquid chromatography coupled with mass spectrometry (UHPLC-MS), remain limited. …”
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Health system costs of providing outpatient care for diabetes in people with TB in the Philippines by T. Yamanaka, M.C. Castro, J.P. Ferrer, J.A. Solon, S.E. Cox, Y.V. Laurence, A. Vassall

“…RESULTS: The mean cost per service ranged from USD0.53 for DM risk assessment to USD23.72 for oral glucose tolerance test. The cost per case detected for different algorithms varied from USD17.43 to USD80.81. …”
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Inhibition of MEK1 Signaling Pathway in the Liver Ameliorates Insulin Resistance by Atsunori Ueyama, Nobuhiro Ban, Masanori Fukazawa, Tohru Hirayama, Minako Takeda, Tatsuo Yata, Hiroyasu Muramatsu, Masaki Hoshino, Marii Yamamoto, Masao Matsuo, Yuka Kawashima, Tatsuhiko Iwase, Takehisa Kitazawa, Youichi Kushima, Yuichiro Yamada, Yoshiki Kawabe

“…Both compounds decreased blood glucose and improved glucose tolerance in doses sufficient to sustain inhibition of extracellular signal-regulated kinase (ERK)1/2 phosphorylation downstream of MEK in insulin-responsive tissues in db/db mice. …”
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A Randomized Controlled Trial of Chinese Medicine on Nonmotor Symptoms in Parkinson’s Disease by Ka-Kit Chua, Adrian Wong, Kam-Wa Chan, Yin-Kei Lau, Zhao-Xiang Bian, Jia-Hong Lu, Liang-Feng Liu, Lei-Lei Chen, Ka-Ho Chan, Kim-Pong Tse, Anne Chan, Ju-Xian Song, Justin Wu, Li-Xing Zhu, Vincent Mok, Min Li

“…In conclusion, long-term administration of JLT is well tolerated and shows significant benefits in improving NMS including mood, cognition, and constipation.…”
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Tryptophan as a biomarker of pregnancy-related immune expression and modulation: an integrative review by Stephanie Prescott, Stephanie Prescott, Natasa Billeci, Melissa Gotcher, Sapna Patel, Addison Almon, Hailey Morgan, Danielle Abukhalaf, Maureen Groer

“…The immunomodulatory role of TRP and its metabolites through the indoleamine 2,3-dioxygenase (IDO) pathway is particularly relevant to pregnancy due to its potential influence on maternal and fetal immune tolerance and the mother's health.MethodsA targeted literature search was conducted via PubMed, Web of Science, and Embase, focusing on maternal serum TRP levels in pregnancy. …”
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