Characterization of the ZDSD Rat: A Translational Model for the Study of Metabolic Syndrome and Type 2 Diabetes by Richard G. Peterson, Charles V. Jackson, Karen Zimmerman, Willem de Winter, Norman Huebert, Michael K. Hansen

“…As disease progressed to overt diabetes, ZDSD rats demonstrated elevated glucose levels, abnormal oral glucose tolerance, increases in HbA1c levels, reductions in body weight, increased insulin resistance with decreasing insulin levels, and dyslipidemia. …”
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The Effects of Baclofen for the Treatment of Gastroesophageal Reflux Disease: A Meta-Analysis of Randomized Controlled Trials by Shujie Li, Shengying Shi, Feng Chen, Jingming Lin

“…All reported side effects of baclofen were of mild-to-moderate intensity, and the drug was well tolerated. Conclusion. Abundant evidence suggests that baclofen may be a useful approach for the treatment of GERD patients; however, a larger well-designed research study would further confirm this recommendation.…”
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Humic Acid Alleviates Low-Temperature Stress by Regulating Nitrogen Metabolism and Proline Synthesis in Melon (<i>Cucumis melo</i> L.) Seedlings by Libao Zhu, Haihe Liu, Yanping Zhang, Yanxia Cao, Yiwen Hu, Yalun Wang, Haiqiang Zheng, Mengze Liu

“…However, the effect of HA on the cold tolerance of melon plants under low-temperature scenarios is still unclear. …”
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The Impact of Creatine Supplementation on Physical Performance, Cognitive Functions, and Safety – A Literature Review by Adam Sobiński, Matylda Czerwonka, Zuzanna Kościuszko, Katarzyna Kurza, Silvia Ciraolo, Julianna Podolec, Agnieszka Kulczycka-Rowicka, Katarzyna Lesiczka-Fedoryj, Joanna Wojda, Anna Walczak

“…These findings support creatine as a versatile, well-tolerated dietary supplement for sports and health applications.   …”
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Efficacy of Anakinra for Various Types of Crystal-Induced Arthritis in Complex Hospitalized Patients: A Case Series and Review of the Literature by A. Aouba, S. Deshayes, L. Frenzel, A. Decottignies, C. Pressiat, B. Bienvenu, F. Boue, G. Damaj, O. Hermine, S. Georgin-Lavialle

“…Crowned dens syndrome patients, including two with pseudogout and one with subacute hydroxyapatite deposition disease, needed 9 to 11 days to achieve complete response. Tolerance to anakinra was good. Conclusion. In case series of complex hospitalized patients, anakinra showed good activity in crowned dens syndrome and associated crystal-induced peripheral arthritis, with longer treatment duration than in gouty arthritis.…”
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SCREENING FOR MAIZE RESISTANT GENOTYPES AGAINST STALK BORERS’ (Sesamia calamistis Hampson) INFESTATION IN MINNA, NIGER STATE, NIGERIA by Idowu, G.A., Oyewale, R.O., Jiboh, B.S., Bolajoko, M.H., Ibrahim, H.M., Bello, A.K

“…Therefore, MG-H and MG-S were recommended as tolerant maize genotypes while MG-C and MG-S were also recommended as high yielding maize genotypes among other genotypes under study.…”
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High Dose Ilaprazole/Amoxicillin as First-Line Regimen for Helicobacter pylori Infection in Korea by WonGun Kwack, YunJeong Lim, ChiYeon Lim, David Y. Graham

“…Compliance rates were high (96.6%) and side effects were minimal and tolerable. Conclusion. A high dose of ilaprazole + amoxicillin was ineffective as the first-line therapy for eradicating H. pylori in Korea. …”
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Efficacy of a “Rescue” Ciprofloxacin-Based Regimen for Eradication of Helicobacter pylori Infection after Treatment Failures by Maria Pina Dore, Vincenza Tadeu, Bianca Are, Ida Mura, Giuseppe Fanciulli, Giovannino Massarelli, Andrea Piana

“…The aim of our study was to evaluate the efficacy and tolerability of a ciprofloxacin-based regimen for H. pylori eradication failures as an alternative to bismuth based quadruple therapy. …”
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A Review of Perfluoroalkyl Acids (PFAAs) in terms of Sources, Applications, Human Exposure, Dietary Intake, Toxicity, Legal Regulation, and Methods of Determination by Katarzyna Sznajder-Katarzyńska, Magdalena Surma, Iwona Cieślik

“…As summarized in this study, PFAAs levels need further assessment due to the science-based TWI standards laid down by the EFSA’s CONTAM Panel regarding the risk to human health posed by the presence of perfluorooctane sulfonic acid and perfluorooctanoic acid in food (tolerable weekly intakes of PFOA and PFOS set up to 6 ng·kg−1·bw·week−1 and 13 ng·kg−1·bw·week−1, respectively). …”
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CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair by Luc Provencher, Wilson Nartey, Peter M. Brownlee, Austin W. Atkins, Jean-Philippe Gagné, Lou Baudrier, Nicholas S. Y. Ting, Cortt G. Piett, Shujuan Fang, Dustin D. Pearson, Shaun Moore, Pierre Billon, Zachary D. Nagel, Guy G. Poirier, Gareth J. Williams, Aaron A. Goodarzi

“…Abstract To tolerate oxidative stress, cells enable DNA repair responses often sensitive to poly(ADP-ribose) (PAR) polymerase 1 and 2 (PARP1/2) inhibition—an intervention effective against cancers lacking BRCA1/2. …”
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The Effect of Goat Grazing on the Biodiversity of Pannonian Dry Grassland by Karoly Penksza, Ferenc Pajor, Andrea Kevi, Zsombor Wagenhoffer, Laszló Sipos, Eszter Salata-Falusi, Peter Penksza, Peter Poti, Jozsef Berke, Denes Salata, Marta Bajnok, Szilard Szentes

“…The overgrazed pasture (N1) exhibited the most degraded vegetation community, dominated by weeds and disturbance-tolerant species. The overgrazed (N1) pasture had a low forage value because of the different timing of treatments. …”
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Continuous Erector Spinae Plane Block for Analgesia after Thoracotomy for Lung Transplantation in an Anticoagulated Patient by Mark Mudarth, Veena Satyapriya, John Coffman, Peter DeSocio, Alec Lawrence, Shana Schwartz, Michael Kushelev

“…These approaches require a needle position in proximity to the neuraxis and may cause significant hypotension that is poorly tolerated in transplant patients. Additionally, the use of anticoagulation or underlying clotting disorder limits the use of these regional blocks because of the concern of hematoma and subsequent neurologic injury. …”
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Modelling and Estimation of Interior Orientation of Non-Metric Cameras using Artificial Intelligence by Hasanain A. Ajjah, Ahmed H H Alboabidallah, Mamoun U. Mohammed, Awesar A. Hussain

“…A reasonably strong relationship between principal distance and principal point with low lens distortion parameters due to the significant relative differences between the distortion parameters, sufficient strength of the relationship between calculating parameters, and estimating according to accuracy tolerance in photogrammetry applications. …”
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The Potential of Virtual Reality for Inducing Neuroplasticity in Children with Amblyopia by María B. Coco-Martin, David P. Piñero, Luis Leal-Vega, Carlos J. Hernández-Rodríguez, Joaquin Adiego, Ainhoa Molina-Martín, Dolores de Fez, Juan F. Arenillas

“…These HMDs are mostly well tolerated by patients during short exposures and do not cause significant long-term side effects, although their use has been occasionally associated with some visual discomfort and other complications in certain types of subjects. …”
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Mineral Composition of Four Edible Mushrooms by S. E. Mallikarjuna, A. Ranjini, Devendra J. Haware, M. R. Vijayalakshmi, M. N. Shashirekha, S. Rajarathnam

“…The mushrooms were safe for consumption, in accordance with the permissible tolerance limits of the estimated toxic metals. Implications of the mineral contents on mushroom nutritional value are highlighted.…”
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Ethylene Response Factor Sl-ERF.B.3 Is Responsive to Abiotic Stresses and Mediates Salt and Cold Stress Response Regulation in Tomato by Imen Klay, Julien Pirrello, Leila Riahi, Anne Bernadac, Ameur Cherif, Mondher Bouzayen, Sadok Bouzid

“…Furthermore, the cold stress essay clearly revealed that introducing antisense Sl-ERF.B.3 in transgenic tomato plants reduces their cell injury and enhances their tolerance against 14 d of cold stress. All these results suggest that Sl-ERF.B.3 gene is involved in plant response to abiotic stresses and may play a role in the layout of stress symptoms under cold stress and in growth regulation under salinity.…”
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Multifaceted roles of melatonin: Investigating coffee leaf melatonin concentration as a potential indicator of vegetative growth by Siswanto Dian, Nanda Aldian Dwi, Muwahida Imroatin, Istiqomah Nurul, Munawarti Aminatun, Mastuti Retno

“…These findings suggest that melatonin is crucial in promoting growth and stress tolerance, particularly in young leaves. Furthermore, the variations in melatonin concentrations between the two species indicate potential species-specific adaptations related to photosynthesis and environmental resilience. …”
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Fungal and oomycete pathogens and heavy metals: an inglorious couple in the environment by Joanna Gajewska, Jolanta Floryszak-Wieczorek, Ewa Sobieszczuk-Nowicka, Autar Mattoo, Magdalena Arasimowicz-Jelonek

“…Despite such adverse effects, published data is indicative of the fact that fungal and oomycete pathogens have a relatively high tolerance to HMs in comparison to other groups of microbes such as bacteria. …”
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The lived experience of Iranian adults from coronavirus disease 2019 (COVID-19)—A qualitative study by Samira Pourmoradian, Arezoo Haghighian-Roudsari, Tahereh Alsadat Khoubbin Khoshnazar, Ali Milani-Bonab

“…The five-stage inductive process to analyze the structure of lived experience (IPSE) approach was used to analyze the data using MAXQDA 2020 software.ResultsAccording to the statements of the participants in the study, five types of experiences extracted during the period of suffering from the disease: nutritional problems, physical problems, the psychological burden caused by the disease, the supporting role of others in the disease tolerance, and the unpleasant and better experiences of the disease.DiscussionPatients with COVID-19 disease experience many physical and psychosocial consequences which affect their quality of life. …”
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Primary Vaginal Myeloid Sarcoma: A Rare Case Report and Review of the Literature by Gaurang Modi, Irappa Madabhavi, Harsha Panchal, Apurva Patel, Asha Anand, Sonia Parikh, Pritam Jain, Swaroop Revannasiddaiah, Malay Sarkar

“…As decitabine therapy was well tolerated, we are continuing in the same way until disease progression without any complications. …”
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