Understanding the exodus: a 15-year retrospective cohort study on the pattern and determinants of migration among Nigerian doctors and dentists by Oghenebrume Wariri, Patience Toyin-Thomas, Itua C.G. Akhirevbulu, Oladapo Oladeinde, Oluchi Omogbai, Philippa Odika, John Osakue, Avwebo Ukueku, Efetobo Orikpete, Chinelo Iwegim, Efe E. Omoyibo, Jermaine Okpere, Uwaila Otakhoigbogie, Ekhosuehi T. Agho, Sunday C. Madubueze, Nnennaya C. Ugoji, Chukwunwike W. Ozegbe, Oti N. Aria, Paul Ikhurionan

“…Significant predictors of migration included younger age, timing of marriage, and residency training status. …”
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First-in-human phase 1 study of the arginase inhibitor INCB001158 alone or combined with pembrolizumab in patients with advanced or metastatic solid tumours by Michael Smith, Aung Naing, Todd Bauer, Kyriakos P Papadopoulos, Osama Rahma, Elena Garralda, Glenn J Hanna, Michael J Pishvaian, Xuejun Chen, Sven Gogov, Omar Saavedra, Howard Kallender, LuLu Cheng, Emil Kuriakose

“…Dose expansion was conducted in tumour-type cohorts (with or without prior anti−PD-1/PD-L1 (programmed death protein 1/programmed death ligand 1) therapy).Results A total of 107 patients received INCB001158 50–150 mg two times per day as monotherapy, and 153 patients, including 6 with moderate renal impairment, received INCB001158 50–100 mg two times per day combined with pembrolizumab. …”
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Assessing the fall risk with Stay Independent Questionnaire in people with stroke by Peiming Chen, Peiming Chen, T. W. Liu, Shamay S. M. Ng, Shamay S. M. Ng

“…The C-SIQ score exhibited significant correlations (ranging from −0.553 to 0.362) with completion times of the TUG and 10 mWT, FMA-LE, BBS, ABC, SIS, CIM score, paretic ankle dorsiflexion strength, and 6 mWT distance. …”
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Brodifacoum causes coagulopathy, hemorrhages, and mortality in rainbow trout (Oncorhynchus mykiss) at environmentally relevant hepatic residue concentrations by Hannah Schmieg, Hermann Ferling, Karina Annika Bucher, Stefanie Jacob, Julia Regnery, Hannah Schrader, Julia Schwaiger, Anton Friesen

“…In the 60 days-experiment, brodifacoum doses ≥ 100 µg/kg body weight caused additionally discoloration, apathy, and anorexia, resulting in reduced weight gain, and ultimately mortality. …”
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Nonfimbrial Adhesin Mutants Reveal Divergent Escherichia coli O157:H7 Adherence Mechanisms on Human and Cattle Epithelial Cells by Matthew R. Moreau, Indira T. Kudva, Robab Katani, Rebecca Cote, Lingling Li, Terrance M. Arthur, Vivek Kapur

“…Supershedding (SS) is a phenomenon that has been reported in some cattle that shed more than 104 colony-forming units of O57:H7 per gram of feces, 100–1000 times more or greater than normal shedders. …”
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Characteristics of nursing homes and early preventive measures associated with risk of infection from COVID-19 in Lazio region, Italy: a retrospective case–control study by Leonardo Palombi, Alessio Abbondanzieri, Stefano Orlando, Tuba Mazhari, Gennaro Cerone, Fausto Ciccacci, Giuseppe Liotta, Sandro Mancinelli, Maria Cristina Marazzi

“…In binary logistic regression models, facilities with more than 15 beds were five times more likely to experience an outbreak than facilities with less than 15 beds OR=5.60 (CI 1.61 to 25.12; p value 0.002); admitting new residents to facilities was associated with a substantially higher risk of an outbreak: 6.46 (CI 1.58 to 27.58, p value 0.004). …”
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Next-generation calcium oxide nanoparticles: A breakthrough in energy storage and humidity sensing by Asif Khan, Syed Tasleem Hussain, Abdul Naeem, Ayesha Sadiqa, Awais Ahmad, Muhammad Aamir Ali Shehzada, Munirah D. Albaqami

“…Humidity sensing response/recovery times of CaO nanoparticles were noted as 79 s and 147 s. …”
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Effects of Probiotic Bacillus sp. on Food Convertion and Growth of Catfish Pangasius hypophthalmus by Dedi Jusadi, E. Gandara, Ing Mokoginta

“…During rearing period, fish were fed on the diet three times a day at satiation. Prior the feeding, probiotic (contained Bacillus sp. 4,2x106 CFU.ml-1) were added into the diet at a dosage of 0, 5, 15 or 25 ml.kg-1 diet. …”
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Preparation of coal kaolinite composites and study of adsorption properties by Rui LIU, Yuping FAN, Ruifeng GUO, Xianshu DONG, Xiaomin MA

“…XPS and FTIR results showed that CK-CTAC/CTS has rich functional groups, which can effectively adsorb Pb(II), and the adsorption equilibrium was approached after 100 min at a solution pH of 6 at 25 ℃. The excellent spatial structure and exposed functional groups of modified kaolinite provided more active sites for adsorption, and the abundant amino and hydroxyl groups of chitosan could chelate and adsorb Pb(II), which synergistically promoted the adsorption performance of the composites higher than that of chitosan or kaolinite alone. …”
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Changes in taste and odor sensitivities during repeated bicycle ergometer exercises by Masataka Narukawa, Kensuke Nojiri, Rina Matsuda, Momo Murata, Seiji Sakate, Sachiko Kuga, Hidetoshi Ue

“…The sensory tests were conducted five times in total: after each exercise segment and once before exercise as a control. …”
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Repetitive Transcranial Magnetic Stimulation for the Treatment of Complex Regional Pain Syndrome: A Pilot Study by Foglia SD, Drapeau CC, Ramdeo KR, Adams FC, Soppitt DB, Rehsi RS, Shanthanna H, Nelson AJ

“…Stevie D Foglia,1 Chloe C Drapeau,2 Karishma R Ramdeo,2 Faith C Adams,2 Daniel B Soppitt,2 Ravjot S Rehsi,2 Harsha Shanthanna,1,3 Aimee J Nelson1,2 1School of Biomedical Engineering, McMaster University, Hamilton, ON, Canada; 2Department of Kinesiology, McMaster University, Hamilton, ON, Canada; 3Department of Anesthesia, McMaster University, Hamilton, ON, CanadaCorrespondence: Aimee J Nelson, Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4K1, Canada, Tel +1 905-525-9140 x28053, Fax +1 905-523-6011, Email nelsonaj@mcmaster.caPurpose: Complex regional pain syndrome (CRPS) is a debilitating chronic pain condition characterized by sensory, motor, and autonomic dysfunction with a world-wide prevalence of 26.2 per 100,000 people per year and is 3 to 4 times more prevalent in females. …”
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Oyster Mushroom (Pleurotus ostreatus) Ethanolic Extract Inhibits Pparg Expression While Maintaining the Methylation of the Pparg Promoter During 3T3-L1 Adipocyte Differentiation by Ariyanto EF, Farahana AK, Sudirman GSJ, Widiarsih E, Qomarilla N, Rahayu NS, Wikayani TP, Heryaman H, Wira DW, Triatin RD, Bashari MH, Pamela Y, Pratiwi YS, Ghozali M

“…The extract was obtained from 80 g of dried oyster mushroom powder extracted three times with 800 mL of ethanol, filtered, evaporated, and reconstituted in dimethyl sulfoxide (DMSO) to final concentrations of 0, 25, 50, and 100 μg/mL, with DMSO limited to 0.5% in all solutions. …”
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Thermodynamic Analysis of CRDI-VCR Type Diesel Engine Fueled with Moringa Oleifera Biodiesel by Vasant Patel, Vyomesh Buch

“…Experiments are performed at four distinct CRs of 15:1, 16:1, 17:1, and 18:1 at 100% loading condition with a fixed engine speed of 1500 rpm, Injection Timing (IT) of 23°before top dead center (bTDC), and Injection Pressure (IP) of 600 bar. …”
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AI-optimized electrochemical aptasensors for stable, reproducible detection of neurodegenerative diseases, cancer, and coronavirus by Amira Elsir Tayfour Ahmed, Th.S. Dhahi, Tahani A. Attia, Fawzia Awad Elhassan Ali, Mohamed Elshaikh Elobaid, Tijjani Adam, Subash C.B. Gopinath

“…Similarly, Square Wave Voltammetry (SWV) and potentiometric sensors have detected alpha-fetoprotein (AFP) at 5 fM and epithelial cell adhesion molecule (EpCAM) at 100 fM, respectively. AI integration also enhances reproducibility, reduces false positives and negatives (from 15-20 % to 5–10 %), and significantly decreases response times (from 10-15 s to 2–3 s). …”
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Non-Linear Biomechanical Evaluation and Comparison in the Assessment of Three Different Piece Dental Implant Systems for the Molar Region: A Finite Element Study by Jesus Alejandro Serrato-Pedrosa, Ignacio Villanueva-Fierro, Rodrigo Arturo Marquet-Rivera, Rosa Alicia Hernández-Vázquez, Salvador Cruz-Lopez, Verónica Loera-Castañeda

“…The results have exhibited an increasing trend to highlight the outstanding behavior of two-piece ceramic implants to dissipate the stress distribution better (6 and 2 times lower than the three- and one-piece systems under occlusal loads and almost 5 and 1.3 times more efficient for oblique loading, respectively), minimize peak stress values (below 100 MPa), and reduce strain peak patterns compared with the other two evaluated designs. …”
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Global Mean and Relative Sea-Level Changes Over the Past 66 Myr: Implications for Early Eocene Ice Sheets by K. G. Miller, W. J. Schmelz, J. V. Browning, Y. Rosenthal, A. V. Hess, R. E. Kopp, J. D. Wright

“…Peak warmth, elevated GMGSL and BSL, high CO2, and ice-free conditions occurred at times in the Paleocene to Eocene (ca. 64, 57.5, 35 Ma) and in much of the Early Eocene (55–48 Ma). …”
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Addressing racial and ethnic disparities in premature exits from permanent supportive housing among residents with substance use disorders by Talia J. Panadero, Sonya Gabrielian, Marissa J. Seamans, Lillian Gelberg, Jack Tsai, Taylor Harris

“…Results In competing risk models, HEVs with at least one SUD had 1.3 times the hazard of negative PSH exits compared to those without SUDs (95% CI: 1.00, 1.61). …”
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The phosphorus negotiation game (P-Game): first evaluation of a serious game to support science-policy decision making played in more than 20 countries worldwide by Nils Haneklaus, Mary Kaggwa, Jane Misihairabgwi, Sherif Abu El-Magd, Naima Ahmadi, Jamal Ait Brahim, Aloyce Amasi, Andrea Balláné Kovács, Łukasz Bartela, Hajar Bellefqih, Redouane Beniazza, Jaroslav Bernas, Essaid Bilal, Tomislav Bituh, Yelizaveta Chernysh, Viktoriia Chubur, Jelena Ćirić, Claudia Dolezal, Andrea Figulová, Janja Filipi, Gordana Glavan, Tibor Guzsvinecz, László Horváth, Sasho Josimovski, Martin Kiselicki, Maja Lazarus, Maja Kazazić, István Komlósi, Ali Maged, Tebogo Mashifana, Gordana Medunić, Emina Mehić, Felhi Mongi, Kelvin Mtei, Dennis Mwalongo, Jerome Mwimanzi, Jakub Nowak, Oqba Basal, Khaoula Qamouche, Małgorzata Rajfur, Hynek Roubík, Mijalche Santa, Cecília Sik-Lányi, Maike Sippel, Gerald Steiner, Anna Skorek-Osikowska, Anton Slavov, Paweł Świsłowski, Ali Tlili, Kalina Trenevska-Blagoeva, Ivan Tschalakov, Tomáš Vlček, Stanisław Wacławek, Ivan Zlatanović, Matúš Mišík, Hendrik Brink, Tzong-Ru Lee

“…In this work the phosphorus negotiation game (P-Game) is for the first time introduced. We present the initial quantitative and qualitative findings derived from engaging 788 students at various academic levels (Bachelor, Master, PhD, and Postdoc) across three continents and spanning 22 different countries. …”
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Mechanism of Photocatalytic Degradation of Diclofenac in Water by a Novel Carbon Nitride by LIU Zi’ang, GAO Yifang, LIU Chao, LI Wenjun, LIU Xiaona, LI Bo, QIAN Tianwei

“…[Findings] The results show that the specific surface area of PCN (133.963 m2/g) is significantly higher than that of GCN (2.605 m2/g), about 67 times that of GCN. PCN (0.20 g/L) can achieve 100% catalytic degradation of DCF (10 mg/L) within 10 min at pH of 5. …”
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Instantaneous self-recovery and ultra-low detection limit hydrogel electronic sensor for temporomandibular disorders intelligent diagnosis by Yujie Yan, Lixia Yu, Xuefeng Zhang, Qi Han, Zhixin Yang, Xingyuan Lu, Jiongke Wang, Hao Xu, Qianming Chen, Hang Zhao

“…It could efficiently diagnose disc displacement with reduction (DDwR) with satisfactory accuracy of 90.00%, and also had a clear indication of the typical clinical manifestations of DDwR and the timing of temporomandibular joint (TMJ) clicking, with a sensitivity of up to 100% in human compared to the diagnostic criteria for TMD (DC/TMD). …”
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