Anti-blastocystis activity of hop extracts in vitro by S.I. Pokhil, V.V. Kazmirchuk, O.M. Tymchenko, V.Y. Yevsiukova, A.L. Melnyk

“…According to the results of in vitro sensitivity of 5 clinical isolates of Blastocystis sp. to the action of carbonic acid hop extract, alcohoicl hop extract and metronidazole, a direct positive pattern in the dose-response and contact time-response effects was established. Alcoholic hop extract showed the highest level of antiblastocystic activity with indicators (for 72-hour parasite cultures) of the minimum inhibitory concentration (which inhibits the parasite cultures growth by 50%) (2.8±0,8) μg/ml and the minimum lethal concentration (which destroys parasite cells by 100%) – 8 μg/ml, being 2.4 and 4.5 times lower than the minimum inhibitory concentration and 8 and 62.5 times lower, than the minimum lethal concentration for hop extract and metronidazole, respectively (p<0.05). …”
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“Common sense is hard work” but benefits from persistent collaboration: Lessons learnt from the development of The Collaborative Network for European Clinical Trials for Children (... by Sabah Attar, Carla Peacock, Mandy Wan, Erin Halil, Chloe Bickerstaff, Lionel Tan, Hafsah Bhatti, Ricardo M. Fernandes, Regis Hankard, Mark A. Turner

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Dual-Stage AI Model for Enhanced CT Imaging: Precision Segmentation of Kidney and Tumors by Nalan Karunanayake, Lin Lu, Hao Yang, Pengfei Geng, Oguz Akin, Helena Furberg, Lawrence H. Schwartz, Binsheng Zhao

“…Objectives: Accurate kidney and tumor segmentation of computed tomography (CT) scans is vital for diagnosis and treatment, but manual methods are time-consuming and inconsistent, highlighting the value of AI automation. …”
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Diagnostic and Predictive Values of Inflammatory Factors in Pathology and Survival of Patients Undergoing Total Cystectomy by Xingxing Tang, Yudong Cao, Jia Liu, Shuo Wang, Yong Yang, Peng Du

“…The median follow-up time was 31 months, and there was no significant difference in OS between the two groups for all IFs. …”
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Acute effects on hepatic biomarkers in the freshwater native fish Aequidens metae exposed to polycyclic aromatic hydrocarbons by W. Corredor-Santamaría, I.C. Calderón-Delgado, Z. Arbeli, J.M. Navas, Y.M. Velasco-Santamaría

“…Phenanthrene reveals for the first time a greater genotoxic effect than benzo[a]pyrene at sublethal concentrations. …”
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Needs Assessment and Tailored Training Pilot for Emergency Care Clinicians in the Prehospital Setting in Rwanda by Naz Karim, Jeanne D’Arc Nyinawankusi, Mikaela S. Belsky, Pascal Mugemangango, Zeta Mutabazi, Catalina Gonzalez Marques, Angela Y. Zhang, Janette Baird, Jean Marie Uwitonze, Adam C. Levine

“…A prospective, nonrandomized, interrupted time-series approach was used. Data collected through closed- and open-ended questionnaires included age, sex, training, and knowledge assessment. …”
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Public Health Discussions on Social Media: Evaluating Automated Sentiment Analysis Methods by Lisa M Gandy, Lana V Ivanitskaya, Leeza L Bacon, Rodina Bizri-Baryak

“…We recommend VADER, the only cost-free tool we evaluated, due to its excellent discrimination, which can be further improved when the comments are at least 100 characters long. If estimating the prevalence of negative comments in an unbalanced dataset is important, we recommend the tone summary measure from LIWC-22. …”
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The Potential Role of sPD-L1 as a Predictive Biomarker in EGFR-Positive Non-Small-Cell Lung Cancer by Vesna Ćeriman Krstić, Dragana Jovanović, Natalija Samardžić, Milija Gajić, Jelena Kotur Stevuljević, Aleksandra Klisic, Ivan Soldatović, Damir Radončić, Marina Roksandić Milenković, Biljana Šeha, Nikola Čolić, Katarina Lukić, Milan Savić

“…However, not all patients treated with these therapies would respond to treatment, and patients who respond to treatment would acquire resistance at some time point. This is why we need new biomarkers that can predict response to therapy. …”
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Feasibility of an indocyanine green-hyaluronic acid mixture (LuminoMark™) for targeting suspicious axillary lymph nodes in patients with breast cancer by Jeeyeon Lee, Byeongju Kang, Jin Hyang Jung, Hye Jung Kim, Won Hwa Kim, Jung Dug Yang, Joon Seok Lee, Yee Soo Chae, Soo Jung Lee, In Hee Lee, Ji-Young Park, Nora Jee-Young Park, Ho Yong Park

“…LuminoMark™, a novel ICG-hyaluronic acid mixture, can provide real-time visualization and minimize dye spread, thereby ensuring a clear surgical field. …”
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Integrative analysis of miRNA expression data reveals a minimal signature for tumour cells classification by Sabrina Napoletano, David Dannhauser, Paolo Antonio Netti, Filippo Causa

“…Our results demonstrate a highly significant differentiation of cancer types, achieving 100 % classification accuracy with minimal training time using a streamlined miRNA signature. …”
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Clinical Features of COVID‐19 Associated Pulmonary Aspergillosis: A Multicenter, Retrospective Study by Yasheng Zhan, Guojun He, Cheng Zhong, Yake Yao, Jiangying Zhou, Tong Li, Hua Zhou

“…All seven cases acquired CAPA in the ICU, six cases during MV, of which five cases received ECMO treatment at the same time, and one case had been off ventilation. The average duration from onset of COVID‐19 to CAPA was 25.4 days, from ICU admission to CAPA was 23.4 days, and from MV to CAPA was 22.1 days. …”
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Volumetric trans-scale imaging of massive quantity of heterogeneous cell populations in centimeter-wide tissue and embryo by Taro Ichimura, Taishi Kakizuka, Yoshitsugu Taniguchi, Satoshi Ejima, Yuki Sato, Keiko Itano, Kaoru Seiriki, Hitoshi Hashimoto, Ko Sugawara, Hiroya Itoga, Shuichi Onami, Takeharu Nagai

“…Using a custom-made giant lens system with a magnification of ×2 and a numerical aperture (NA) of 0.25, and a CMOS camera with more than 100 megapixels, we built a trans-scale scope AMATERAS-2, and realized fluorescence imaging with a transverse spatial resolution of approximately 1.1 µm across an FOV of approximately 1.5×1.0 cm2. …”
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The levels of osteopontin in human milk of Chinese mothers and its associations with maternal body composition by Huijuan Ruan, Qingya Tang, Xuan Zhao, Yajie Zhang, Xuelin Zhao, Yi Xiang, Wei Geng, Yi Feng, Wei Cai

“…Conclusions: The levels of OPN in human milk of Chinese mothers showed dynamic changes with the extension of lactation time. The OPN in human milk was related to the mother’s body composition but not related to related humoral factors.…”
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Effectiveness of Video Teletherapy in Treating Obsessive-Compulsive Disorder in Children and Adolescents With Exposure and Response Prevention: Retrospective Longitudinal Observati... by Jamie D Feusner, Nicholas R Farrell, Mia Nunez, Nicholas Lume, Catherine W MacDonald, Patrick B McGrath, Larry Trusky, Stephen Smith, Andreas Rhode

“…The median amount of therapist involvement was 13 (IQR 10.0-16.0) appointments and 11.5 (IQR 9.0-15.0) hours. …”
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PICC catheterization and maintenance for severely and critically ill patients with COVID-19 in the isolation ward (隔离病房重型和危重型新型冠状病毒肺炎患者PICC置管管理)... by HAN Huishan (韩会山), LI Naxin (李纳新), LYU Yuan (吕源), LI Yuhua (李玉华), LI Yali (柳雅立)

“…These patients were all given standardized protective measures during the PICC operation. The one-time success rate of catheterization was 100. 00%. …”
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One-pot synthesis and characterization of a BSA-Cu2S/CuS quantum dots drug delivery system based on biuret’s reaction by Porfirio Estrada-Rojas, Juan Francisco Hernández-Paz, Claudia Alejandra Rodríguez-González, Mónica Elvira Mendoza-Duarte, Santos Adriana Martel-Estrada, Laura Elizabeth Valencia-Gómez, Héctor Camacho-Montes, Imelda Olivas-Armendáriz

“…Due to the lower protein concentration, which provides fewer nucleation sites, sample A (BSA concentration 5 mg ml ^−1 ) showed a particle size distribution over 100 nm and low stability over time. Sample B (25 mg ml ^−1 BSA) and C (50 mg ml ^−1 BSA) showed excellent stability and particle sizes within the expected range for Cu _2 S and CuS quantum dots (<2.4 nm). …”
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Effects of Replacing Inorganic Sources of Copper, Manganese, and Zinc with Different Organic Forms on Mineral Status, Immune Biomarkers, and Lameness of Lactating Cows by Manqian Cha, Xingjun Ma, Yunlong Liu, Shengyang Xu, Qiyu Diao, Yan Tu

“…Repeated-measure mixed models were used to evaluate the effects on trace mineral status over time. As the responses with the MHAC and AAC forms were similar, the treatments were also analyzed as organic trace minerals (OTMs, combining the MHAC and AAC groups, <i>n</i> = 40) versus inorganic trace minerals (ITMs, the S group, <i>n</i> = 20). …”
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Effect of Repetitive Transcranial Magnetic Stimulation Combined with Exercise Therapy on the Motor Function in Stroke Patients with Hemiplegia by Wani ZHOU, Lei ZHANG, Rundong LI, Kaiquan XU, Chengji WU

“…Objective:To discuss the effect of repetitive transcranial magnetic stimulation (rTMS) combined with exercise therapy on the motor function in stroke patients with hemiplegia.Methods:A total of 100 stroke patients with hemiplegia were selected from September 2016 to September 2018, according to the random number table, and they were divided into excitation group and exercise group, with 50 cases in each group. …”
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A Step towards Integrating CMORPH Precipitation Estimation with Rain Gauge Measurements by Augusto José Pereira Filho, Felipe Vemado, Guilherme Vemado, Fábio Augusto Gomes Vieira Reis, Lucilia do Carmo Giordano, Rodrigo Irineu Cerri, Cláudia Cristina dos Santos, Eymar Silva Sampaio Lopes, Marcelo Fischer Gramani, Agostinho Tadashi Ogura, José Eduardo Zaine, Leandro Eugenio da Silva Cerri, Oswaldo Augusto Filho, Fernando Mazzo D’Affonseca, Cláudio dos Santos Amaral

“…Early comparisons indicated high discrepancies between daily rain gauge rainfall measurements and respective CMORPH areal rainfall accumulation estimates that tended to be reduced with accumulation time span (e.g., yearly accumulation). Current results show CMORPH systematically underestimates daily rainfall accumulation along the coastal areas. …”
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Hospital Prevalence of Colorectal Cancer among Colonoscopy Recipients Attending a Tertiary Hospital in Oman: A Cross-Sectional Study by Alanoud F. Alsumait, Yahya M. Al-Farsi, Mostafa I. Waly, Issa S. Al-Qarshoobi, Samir Al-Adawi, Nawaf H. Albali, Mansour S. Al-Moundhri

“…CRC prevalence estimates were calculated over age, gender, governorate, and time of follow-up. Results. A total of 442 CRC cases were enumerated among 3701 colonoscopies, with an overall CRC prevalence estimate of 11.9 per 100 colonoscopies (95% CI: 10.9, 13.0). …”
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