Five-Year Predictors of Insulin Initiation in People with Type 2 Diabetes under Real-Life Conditions by Sandro Gentile, Felice Strollo, Francesca Viazzi, Giuseppina Russo, Pamela Piscitelli, Antonio Ceriello, Carlo Giorda, Piero Guida, Paola Fioretto, Roberto Pontremoli, Salvatore De Cosmo, the AMD-Annals Study Group

“…Multivariate analysis identified diabetes duration, HbA1c, triglyceride and low HDL-C values, presence of retinopathy or renal dysfunction, and sulphonylurea utilization (the risk being approximately 3 times greater in the latter case) as independent predictors of insulin treatment initiation. …”
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Large Scale Experiments Representing a Containment Natural Circulation Loop during an Accident Scenario by R. Kapulla, G. Mignot, S. Paranjape, M. Andreani, D. Paladino

“…It is shown that the presence of the damper has a strong effect on the resulting helium content in the inner zone with 3 times less helium at the end of the test compared with the configuration without damper. …”
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Neurological syndromes associated with COVID-19: a multicenter study in Brazil by Aline de Moura Brasil Matos, Andre Borges Ferreira Gomes, Fernanda Martins Maia Carvalho, Francisco Tomaz Meneses de Oliveira, Lohana Santana Almeida da Silva, Flavia Esper Dahy, Joao Victor Luisi de Moura, Marcela Vieira Freire, Jose Ernesto Vidal, Rosa Maria Nascimento Marcusso, Jerusa Smid, Victor Rebelo Procaci, Rodrigo Meireles Massaud, Felipe Von Glehn, Jorge Casseb, Camila Malta Romano, Augusto Cesar Penalva de Oliveira, on behalf of NeurocovBR study group

“…Those developing vascular syndromes patients were 3 times more likely to require ICU (χ2 (1) = 37.12, p < 0.01, OR = 3.78) and 4 times more likely to die (χ2 (1) = 58.808, p < 0.01, OR = 4.73) than patients with vascular syndromes due to different etiologies. …”
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Unlocking the full potential of resistance training: a comparative analysis of low- and high-intensity effects on neurotrophic growth factors and homocysteine by Chongwen Zuo, Yi Yin, Zhiyang Zheng, Ren Mu, Yuxin Liang, Shan Wang, Chaoqun Ye

“…Blood samples were collected at three time points: pre-training, post training, and after 30 min of rest to measure changes in serum lactate, serum brain-derived neurotrophic factor (BDNF), insulin-like growth factor 1 (IGF-1), vascular endothelial growth factor (VEGF), irisin, and plasma homocysteine (Hcy) levels. …”
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Management of Psychosis and Schizophrenia by Primary Care GPs: A Cross-Sectional Study in Spain by Jesús Sepúlveda-Muñoz, Casta Quemada González, María M. Hurtado Lara, Ángel Manuel Gutiérrez García, Celia Martí-García, José María García-Herrera Pérez-Bryan, José Miguel Morales-Asencio

“…Physicians typically managed 0-10 patients with diagnosed schizophrenia and saw these patients 2 to 3 times annually. They often felt capable of managing these patients, especially with mental health consultancy support. …”
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Carbon sequestration rate in sediment mangroves from natural and rehabilitated mangroves by D. Ariyanto, D. Pringgenies

“…The carbon sequestration rate values showed 1.65–3.14 for natural mangroves and 0.29–1.25 for rehabilitated mangroves, thus establishing that the rate is higher (2–3 times) in natural mangroves than in rehabilitated mangroves.…”
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SDG11-Based Sustainability Assessment of Urban Communities: A Case Study of Changsha by Qin Shuqian, Zhang Nan, Zhu Peijuan, Zhang Yong, Zhang Chen

“…The empirical part of the study takes the statutory communities in the built-up area of Changsha as the research object and carries out the assessment of community sustainability at three time points: 2010, 2015, and 2020. This help in grasping the temporal and spatial heterogeneity of community sustainability and its law of evolution at the city level and provide scientific support for carrying out refined urban planning and community governance. …”
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Multiplex Bead Array Assay for Detection of 25 Soluble Cytokines in Blister Fluid of Patients with Complex Regional Pain Syndrome Type 1 by Claudia Heijmans-Antonissen, Feikje Wesseldijk, Renate JM Munnikes, Frank JPM Huygen, Patrick van der Meijden, Wim C. J. Hop, Herbert Hooijkaas, Freek J. Zijlstra

“…However, detection levels and amounts measured are at least 3 times higher in the multiplex-25 array assay than in the ELISA assays used simultaneously for the measurement of cytokines.…”
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Recovery of the Intestinal Microbiota Metabolic Activity in Patients with Bronchial Asthma by O. Yu. Zolnikova, N. D. Potskhverashvili, N. I. Kokina

“…For the treatment of SIBO, 10 patients were prescribed rifaximin-α at a dose of 200 mg × 3 times a day for 7 days, 10 patients were prescribed rifaximin-α at the same dose, followed by the administration of the Lactobalans drug containing at least 3.0×109 CFU/caps. probiotic microorganisms (Lactobacillus gassery KS-13, Lactobacillus gasser LAC-343, Lactobacillus ramnosus LCS-742, Bifi dobacterium bifi dum G9-1, Bifi dobacterium longum MM-2, Bifi dobacterium longum BB536 Strain M, Bifi dobacterium biumidum BB536 Strain M. …”
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Improved primary stability and load transfer of a customized osseointegrated transfemoral prosthesis compared to a commercial one by Giulia Galteri, Valentina Betti, Domenico Alesi, Stefano Zaffagnini, Marco Palanca, Emanuele Gruppioni, Luca Cristofolini

“…The rotational inducible micromotions of the OsteoCustom stem were more than 3 times smaller than the commercial one (p < 0.05). …”
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Influence of volatiles (H$_{2}$O and CO$_{2}$) on shoshonite phase equilibria by Vetere, Francesco, Namur, Olivier, Holtz, Francois, Almeev, Renat, Donato, Paola, Frondini, Francesco, Cassetta, Michele, Pisello, Alessandro, Perugini, Diego

“…This result has important consequences upon the physical properties of the magma because it influences its viscosity and, as a consequence, velocity during its travel to the Earth surface.Assuming that the widths of Vulcanello conduits vary from 0.5 to 1.5 m, estimates of the ascent velocity vary in the range 1.5 ${\times }$ 10$^{-4}$–3.5 ${\times }$ 10$^{-2}$ m${\cdot }$s$^{-1}$ for CO$_{2}$ free systems and from 5.7 ${\times }$ 10$^{-4}$–1.3 ${\times }$ 10$^{-1}$ m${\cdot }$s$^{-1}$ for CO$_{2}$ bearing systems.Since shoshonitic magmas are common not only in the Italian volcanic provinces (Aeolian Arc, Campi Flegrei, Ischia Island, Pontine Islands, Monti Cimini, Monte Amiata, Capraia Island, Radicofani, Roccamonfina) but also in different volcanoes worldwide (Yellowstone, Mariana Arc, Kurile Arc, Tonga Arc, Andean Arc, Kamchatka Arc), we suggest that the new data will be useful to better understand shoshonitic magma behaviour under relevant geological scenarios. …”
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Effectiveness of Intravitreal Ranibizumab in Nonvitrectomized and Vitrectomized Eyes with Diabetic Macular Edema: A Two-Year Retrospective Analysis by Ozgun Melike Gedar Totuk, Ayse Yagmur Kanra, Mohammed Nadim Bromand, Guler Kilic Tezanlayan, Sevil Ari Yaylalı, Irem Turkmen, Aylin Ardagil Akcakaya

“…IVR injection was performed 6.3 times in vitrectomized eyes and 6.1 times in nonvitrectomized eyes during the 24-month period (p>0.05). …”
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Efficacy of Physiologically Active nutrients in the Treatment of Asthenic Disorders in Patients with Chronic Diffuse Liver Diseases by M. V. Mayevskaya, M. A. Morozova, A. G. Beniashvili, V. D. Lunkov, V. T. Ivashkin

“…The nutraceutical product (curcumin, piperine, tanshinone IIA, choline; standardized for curcumin and choline) was assigned 1 pill 3 times a day with meals for 4 weeks. To objectify common symptoms, we used a D-FIS questionnaire (Daily Fatigue Impact Scale), a 4DSQ Four-Dimensional Symptom Questionnaire for assessing distress, depression, anxiety and somatization, and a SF-36 questionnaire for assessing the quality of life.Results. …”
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Growth of Zinc Oxide Nanorods with the Thickness of Less than or Equal to 1 μm through Zinc Acetate or Zinc Nitrate for Perovskite Solar Cell Applications by Albertus Bramantyo, Kenji Murakami, Masayuki Okuya, Arief Udhiarto, Nji Raden Poespawati

“…The seed layer was applied by spin coating with a three-time repetition (n) and rotational speed (v) at 3000 rpm. …”
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The effect of Tai Chi on plasma homocysteine in 1176 adults: a propensity score matching-based study by Yingchun Gu, Juncai Bai, Yang Li, Ling Han, Dongwei Wang

“…In the Tai Chi group, the type of exercise was 24 simplified forms of Tai Chi, at least 3 times/week for 30–60 min/ time. The median duration of practice for Tai Chi group was 26.5 (11,41) years. …”
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High Prevalence of Prediabetes and Associated Risk Factors in Urban Areas of Pontianak, Indonesia: A Cross-Sectional Study by Indah Budiastutik, Martha I. Kartasurya, Hertanto W. Subagio, Bagoes Widjanarko

“…The exercise frequency was mostly less than 3 times/week, and the BMI was mainly classified as overweight and obese. …”
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Efficacy, Feasibility, and Acceptability of an Emotional Competence Tele-Intervention for Mandarin-Speaking Children Aged 5 to 7 Years With Developmental Language Disorder: Pilot S... by Hsin-Hui Lu, Shih-Yuan Liang, Yi-Chia Huang

“…These data were individually collected at 3 time points after study 1 (time 1). These phases included baseline (time 1 to time 2), during the tele-intervention (time 2 to time 3), and follow-up (time 3 to time 4), spanning approximately 18 to 20 weeks from time 1 to time 4. …”
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Social issues in general practice – a survey assessing the interprofessional perspective of general practitioners and social workers regarding frequency, challenges, and needs by Tonia Gerber, Laura Diaz Hernandez, René Rüegg, Dunja Vetter, Andreas Zeller

“…More than half of GPs (56.0%) reported having contact with social workers less than once a month, while approximately half of the social workers reported having contact with GPs 1 to 3 times a month (48.7%). GPs (69.3%) and social workers (76.3%) would like more contact. …”
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Utilization of MS 222 in Transport of Catfish (Pangasius sutchi) Seed by Harton Arfah, Eddy Supriyono

“…After putting the fish into the plastic bag, it was filled up with oxygen, which the volume was 3 times than water volume, than the plastic bag was closed by tying it.  …”
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Glycogen Storage Disease Type Ia: A Retrospective Claims Analysis of Complications, Resource Utilization, and Cost of Care by Eliza Kruger, Justin Nedzesky, Nina Thomas, Jeffrey D. Dunn, Andrew A. Grimm

“…Patients with GSDIa more often required hospitalization (0.53 vs 0.06 hospitalizations per patient per year) vs comparators, including 2 or more hospitalizations (26.6% vs 2.3%), longer length of stay (3.1 vs 0.4 days), and more annual visits in all care settings, including 4.3 times more visits in the emergency department. Mean annual total healthcare costs were higher for GSDIa patients vs comparators ($33 910 vs $4410). …”
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