Real world efficacy and safety of the advanced hybrid closed-loop system MiniMed 780G (SmartGuard) in children under 7 years of age by Sara López-López, Cristina Díaz-Martín, Inés García-de Pablo, María Teresa Ovejero-Garcia, María Beatriz Garnier-Rodríguez, Ruth Molina-Suárez, Cristina Ontoria-Betancort, Blanca Sáez-Gallego, Ángela Domínguez-García, Sofía Quinteiro-González, Lourdes Travieso-Suárez, María Fátima Cabrera-Guedes, Yeray Nóvoa-Medina, Yeray Nóvoa-Medina, Yeray Nóvoa-Medina

“…ObjectiveTo evaluate the safety and efficacy of the Medtronic 780G SmartGuard™ AID system in children under 7 years of age with type 1 diabetes (T1D).MethodsRetrospective analysis of data from children living with T1D under 7 years of age using the MiniMed 780G™ across three pediatric endocrinology units in the Canary Islands. …”
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Comparison of 10-year atherosclerotic cardiovascular disease (ASCVD) risk in metropolitan and rural areas of South of Iran by Mohammad Javad Zibaeenezhad, Mehrab Sayadi, Hossein Pourmontaseri, Davood Khalili, Mojtaba Farjam, Ehsan Bahramail, Nader Parsa, Azizallah Dehghan, Seyyed Saeed Mohammadi, Iman Razeghian-Jahromi, Hamed Bazrafshan drissi, Matin Sepehrinia

“…After adjustment for all confounders, living in the urban areas seemed to be associated with higher atherosclerotic CVD risk (β = 0.78, 95%CI: [0.69–1.05]), which was consistent across both sexes. …”
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Interventions by Cardiovascular Drugs Against Aircraft Noise-Induced Cardiovascular Oxidative Stress and Damage by Marin Kuntić, Ivana Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Dilja Krueger-Burg, Huige Li, Sebastian Steven, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber

“…At least 20% of the European Union’s population lives in noise-polluted areas with exposure levels exceeding the recommended limits of the World Health Organization, which is considered unhealthy by the European Environment Agency. …”
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Child undernutrition and its association with household environmental conditions in Bangladesh by Md Mostaured Ali Khan, Md Arif Billah, Kaniz Fatima, M Mofizul Islam, Bidhan Krishna Sarker, Shimlin Jahan Khanam, Aduragbemi Banke-Thomas, Md Nuruzzaman Khan

“…Results: The prevalence of stunting, wasting and underweight in Bangladesh was 31%, 8%, and 22%, respectively, with notable urban–rural variations. Under-5 children who lived in houses constructed with unimproved materials (aRR: 1·17), exposed to household air pollution (aPR: 1·37), had unimproved drinking water sources (aPR: 1·28) or had poor handwashing facilities (aPR: 1·24) had a greater likelihood of stunting compared to their counterparts. …”
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Genetic disruption of Blimp-1 drastically augments the antitumor efficacy of BCMA-targeting CAR T cells by Anthony M. Battram, Joan Mañé-Pujol, David F. Moreno, Aina Oliver-Caldés, Judit Carpio, Oriol Cardus, Luis Gerardo Rodríguez-Lobato, Álvaro Urbano-Ispizua, Carlos Fernández de Larrea

“…This lack of durability has been attributed to the premature terminal differentiation of CAR T cells, which prevents the formation of long-lived memory cells that maintain antitumor responses. …”
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Asymptomatic testing people for SARS-CoV-2 in healthcare facilities: A systematic review by Olabisi A. Oduwole, Glory Bassey, Grace Esebanmen, Samuel Shoyinka, Johnsolomon Ohenhen, Elise Cogo, Nicholas Henschke, Eleanor Ochodo, Martin M. Meremikwu

“…Aim: To evaluate the effectiveness of testing asymptomatic individuals visiting, living or working in healthcare facilities in reducing SARS-CoV-2 viral infections. …”
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Health and Educational Inequalities among the Third Gender Community in Lahore, Pakistan by Ayesha Humayun, Muhammad Hassan, Hira Ashfaq, Zulqarnain Haider, Nauman Naeem, Mubashar Munir

“…This study aims to explore the educational and healthcare challenges faced by this community, as perceived by its members, to gain deeper insight into the complexities of their lived experiences. Methodology:  This qualitative study conducted in-depth interviews with ten hijra individuals from three areas in Lahore, Pakistan. …”
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Gradient disparities in allergy and the gut microbiome among rural, migrant, and urban populations across China by Wanjun Wang, Mo Xian, Ruchong Chen, Jing Li, Lulu Wu

“…Conclusion: The Der p-sIgE responses and the composition of gut microbiota differs synchronously with extended living time in an urban area. Studies in immigrants provide a unique opportunities to evaluate the effects of environmental factors in the pathogenesis of allergic disorders.…”
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Occurrence of Helicobacter pylori in drinking water sources and antimicrobial resistance profile in the central region of Peru by María Custodio, Raúl Montalvo-Otivo, Jhonatan Crispín-Ayala, Jeampier Bendezu-Meza, Pilar Herrera-Quintana, Heidi De la Cruz, Javier Huarcaya

“…The determinants of the infection rate are socioeconomic status, low standard of living and overcrowding. In addition, exposure to environmental sources contaminated with feces, such as water and vegetables, is another risk factor for infection. …”
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A legume-enriched diet improves metabolic health in prediabetes mediated through gut microbiome: a randomized controlled trial by Xiaorong Wu, Alvin Surya Tjahyo, Vera Sergeyevna Brok Volchanskaya, Long Hui Wong, Xianning Lai, Yi Ning Yong, Farhana Osman, Shia Lyn Tay, Priya Govindharajulu, Shalini Ponnalagu, Rachel Tso, Hwee Sze Teo, Kaijie Khoo, Huan Fan, Chew Chan Goh, Clara Poh Lian Yap, Melvin Khee-Shing Leow, Christiani Jeyakumar Henry, Sumanto Haldar, Kevin Junliang Lim

“…We investigated effects of a calorie-restricted, legume-enriched, multicomponent intervention diet compared with a calorie-restricted control diet in 127 Chinese prediabetes participants, living in Singapore. The study was a 16-week, single-blind, parallel-design, randomized controlled trial (n = 63 intervention group (IG), n = 64 control group (CG); mean ± SD age 62.2 ± 6.3 years, BMI 23.8 ± 2.6 kg/m2). …”
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Opening up Corpus FinSL: enriching corpus analysis with linguistic ethnography in a study of constructed action by Puupponen Anna, Hodge Gabrielle, Anible Benjamin, Salonen Juhana, Wainio Tuija, Keränen Jarkko, Hernández Doris, Jantunen Tommi

“…We argue that this kind of approach enables signed language corpus linguistics to “open up” more to signers’ lived experiences, while still “tying down” empirical descriptions of FinSL. …”
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Employing a low-code machine learning approach to predict in-hospital mortality and length of stay in patients with community-acquired pneumonia by Hao Chen, Shurui Zhang, Hiromi Matsumoto, Nanami Tsuchiya, Chihiro Yamada, Shunsuke Okasaki, Atsushi Miyasaka, Kentaro Yumoto, Daiki Kanou, Fumihiro Kashizaki, Harumi Koizumi, Kenichi Takahashi, Masato Shimizu, Nobuyuki Horita, Takeshi Kaneko

“…For the LOS, the CCI score, activities of daily living, and social support were significant predictors. …”
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Interest, uptake, and feasibility trial of a real-life digital health intervention to improve lifestyle in Brazil by Raquel B De Boni, Jurema C Mota, Michael Duncan, Leonardo Linconl, Giovanna Lucieri Alonso Costa, Sofia Pimentel, Kamila P Sales, Fabiana Gaspar, Fernanda Adaes, Felipe B Schuch, Vicent Balanzá-Martinez, Flavio Kapczinski, Renato S Lima

“…Participants were adults who lived in Rio de Janeiro and reported using the Brazilian Public Health System. …”
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Symptoms indicative of early knee osteoarthritis after ACL reconstruction: descriptive analysis of the SHIELD cohort by Anna Cronström, May Arna Risberg, Martin Englund, Dorthe B. Strauss, Paul Neuman, Carl Johan Tiderius, Eva Ageberg

“…Symptoms indicative of early knee OA were evaluated by the Knee injury and Osteoarthritis Outcome Score (KOOS) subscale pain, KOOS subscale pain ≤72 (KOOSpain ≤72), and ≤85 on two out of four KOOS subscales (pain, symptoms, activity of daily living, quality of life) (modified Luyten). Results: Mean (SD) KOOS pain scores were 83.2 (15.7) and 87.3 (12.7) at 1 and 3 years, respectively. …”
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Chaetoceros muelleri sulfated polysaccharides: chain conformation, physical characteristics, and morphology by Valeria Miranda-Arizmendi, Jorge Marquez-Escalante, Agustin Rascon-Chu, Karla Martínez-Robinson, Francisco Brown-Bojorquez, Elizabeth Carvajal-Millan

“…The practical and theoretical significance of studying polysaccharides lies in the numerous essential functions these macromolecules fulfill in living organisms, and the important industrial and technological purposes they serve. …”
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Scalable Manufacturing Method for Model Protein-Loaded PLGA Nanoparticles: Biocompatibility, Trafficking and Release Properties by Selin Akpinar Adscheid, Marta Rojas-Rodríguez, Salma M. Abdel-Hafez, Francesco S. Pavone, Marc Schneider, Akif E. Türeli, Martino Calamai, Nazende Günday-Türeli

“…We tested the biocompatibility of the NPs in living RPMI 2650 and neuroblastoma cell lines, as well as their trafficking and uptake. …”
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Decoding the mannose receptor-mAb interaction: the importance of high-mannose N-glycans and glycan-pairing by Julia Baumeister, Maximilian Meudt, Sybille Ebert, Frank Rosenau, Boris Mizaikoff, Michaela Blech, Kristina M. J. Aertker, Fabian Higel

“…Previous reports have shown that mAbs containing high-mannose N-glycans are cleared faster from blood circulation, leading to reduced half-lives. The high-mannose N-glycan content of mAbs can be influenced during the cell culture process by factors such as cell lines, process conditions, and media. …”
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Global, regional, and national survey on burden and quality of care index (QCI) of nasopharyngeal cancer: A systematic analysis of the Global Burden of disease study 1990–2019 by Saba Ilkhani, Sahar Saeedi Moghaddam, Delaram Sakhaei, Mohammad-Mahdi Rashidi, Sina Azadnajafabad, Mohammadreza Azangou-Khyavy, Naser Ahmadi, Ozra Tabatabaei-Malazy, Mohammadreza Naderian, Erfan Ghasemi, Parnian Shobeiri, Sahar Mohammadi Fateh, Farzad Kompani, Bagher Larijani, Farshad Farzadfar

“…Methods: We gathered epidemiologic metrics (incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life years (DALYs) from Global Burden of Disease (GBD) study data. …”
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Impact of Abdominal Obesity on Thyroid Auto-Antibody Positivity: Abdominal Obesity Can Enhance the Risk of Thyroid Autoimmunity in Men by Jazyra Zynat, Suli Li, Yanrong Ma, Li Han, Fuhui Ma, Yuyuan Zhang, Bei Xing, Xinling Wang, Yanying Guo

“…A total of 2253 residents who had lived in Xinjiang for more than 3 years were enrolled. …”
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Clinical efficacy of a virtual reality tool for the treatment of obesity: study protocol of a randomised controlled trial by Dimitra Anastasiadou, Jose Antonio Ramos-Quiroga, Mel Slater, Bernhard Spanlang, Desiderio Cano Porras, Marta Comas, Andreea Ciudin, Gemma Parramon Puig, Julia Vázquez-De Sebastián, Pilar Lusilla-Palacios

“…Moreover, these combined interventions have the potential to improve health-related outcomes of people living with obesity (PLWO) and to afford maintenance of behavioural changes over time. …”
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