Placental malaria infection is associated with downregulation of STAT-6 and ANG-1 in decidual macrophages by Fred Owino, Fred Owino, Fred Owino, Caroline Kijogi, Caroline Kijogi, Caroline Kijogi, Omu Anzala, Omu Anzala, Edwin Walong, Obiero Jael, Steven G. Nyanjom, Agola Lelo Eric, Bernard N. Kanoi, Bernard N. Kanoi, Jesse Gitaka, Jesse Gitaka

“…Here, we determined the influence of placental malaria on decidual macrophages, by assessing their distribution based on their unique phenotypes, and examining their expression levels of transcription factors as well as angiogenic factors, in placentas from women living in a malaria-endemic area.MethodsWe compared these macrophage parameters in placentas from malaria infected women to those from the uninfected women. …”
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Phenotypic and genetic extended spectrum beta lactamase profiles of bacterial isolates from ICU in tertiary level hospital in Kenya [version 2; peer review: 2 approved] by Edwin O. Magomere, Lucy Muchiri, Leon Otieno, Frank G. Onyambu, Ali Kassim, Job Mwale, Brian Maina

“…Background Bacterial infections in the Intensive Care Units are a threat to the lives of critically ill patients. Their vulnerable immunity predisposes them to developing bacteria-associated sepsis, deteriorating their already fragile health. …”
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Characterisation of internal tremors and vibration symptoms by Harlan M Krumholz, Mitsuaki Sawano, Richa Sharma, Tianna Zhou, Dorothy Massey, Anna D Baker, Diana Berrent Güthe, Nick Güthe, Suzanne Pincus Shidlovsky, Liza Fisher, Connor B Grady, Cesar Caraballo

“…These domains were as follows: (1) symptom experience, description and anatomic location; (2) initial symptom onset; (3) symptom timing; (4) symptom triggers or alleviators; (5) change from baseline health status; (6) experience with medical establishment and (7) impact on individuals’ lives and livelihood. There were 22 themes in total, each corresponding to one of the broader domains. …”
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Cost of introducing and delivering malaria vaccine (RTS,S/AS01E) in areas of seasonal malaria transmission, Mali and Burkina Faso by Jean Bosco Ouédraogo, Alassane Dicko, Ranju Baral, Clint Pecenka, Halimatou Diawara, Fadima Yaya Bocoum, Ann Levin, Cynthia Lee, Fatoumata Koita, Rosemonde Guissou, Seydou Yabré, Seydou Traoré, Winthrop Morgan

“…Background The WHO recommends use of the RTS,S/AS01E (RTS,S) malaria vaccine for young children living in areas of moderate to high Plasmodium falciparum malaria transmission and suggests countries consider seasonal vaccination in areas with highly seasonal malaria. …”
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Women’s experiences of gender-based violence supports through an intersectional lens: a global scoping review by Amaya Perez-Brumer, Beverley M Essue, Cyndirela Chadambuka, Isabel Arruda-Caycho, Danielle Tocallino, Rebecca Balasa, Prossy Kiddu Namyalo, Carmina Ravanera, Sarah Kaplan

“…Findings reflected intersectional differences in women’s experiences of accessing GBV services across contexts and lived experiences. Common findings indicate that seeking GBV support was motivated and enabled by informal supports and positive prior experiences in accessing services. …”
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Estimated cumulative incidence of intervention by children's social care services to age 18: a whole-of-England administrative data cohort study using the child in need census by Matthew A Jay, Patricio Troncoso, Andy Bilson, Dave Thomson, Richard Dorsett, Rachel Pearson, Bianca De Stavola, Ruth Gilbert

“…Results Of all children living in England, before turning 18, 35.4% were referred, 32.3% were assessed, 25.3% were recorded as CiN and 6.9% were subject to a CPP (37.5%, 34.6%, 26.0% and 7.1%, respectively, in sensitivity analyses). …”
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Twelve-Month Retention in and Impact of Enhance®Fitness on Older Adults in Hawai‘i by Michiyo Tomioka, Kathryn L. Braun, Yan Yan Wu, Kay Holt, Paula Keele, Lori Tsuhako, Johnny Yago

“…Besides continuous attendance, performance-measure improvements were associated with younger age, male gender, living with others (vs. alone), and fewer chronic conditions. …”
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Low-Dose Ketamine Infusion for Perioperative Pain Management in Patients Undergoing Laparoscopic Gastric Bypass: A Prospective Randomized Controlled Trial by Mitchell T. Seman, Shawn H. Malan, Matthew R. Buras, Richard J. Butterfield, Kristi L. Harold, James A. Madura, David M. Rosenfeld, Andrew W. Gorlin

“…The patient satisfaction questionnaires showed a significant difference with the ketamine group reporting lower maximum pain scores, a decrease in how pain limited activities of daily living once discharged, and increased hospital pain management satisfaction scores. …”
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Dye-based fluorescent organic nanoparticles made from polar and polarizable chromophores for bioimaging purposes: a bottom-up approach by Daniel, Jonathan, Dal Pra, Ophélie, Kurek, Eleonore, Grazon, Chloé, Blanchard-Desce, Mireille

“…Furthermore, ultrabright dFONs of different colors that internalize into cells can be tracked within living cells allowing real-time multicolor single particles tracking. …”
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Clinical outcomes over 2 years following arthroscopic ankle lateral ligament repair with os subfibulare by Shohei Sano, Noriyuki Kanzaki, Kiminari Kataoka, Koji Nukuto, Tetsuya Yamamoto, Yuta Nakanishi, Kyohei Nishida, Kanto Nagai, Yuichi Hoshino, Takehiko Matsushita, Ryosuke Kuroda

“…The mean scores for pain and related symptoms, foot function and activities of daily living, social functioning, shoe-related, and general health and well-being subscales of the SAFE-Q also showed significant improvements in both groups. …”
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A systematic review and mapping exercise to assess the content validity of patient-reported outcome measures for adults having reconstructive surgery of the lower limb by Jennie Lister, Sophie James, Hemant K. Sharma, Catherine Hewitt, Helen Fulbright, Heather Leggett, Catriona McDaid

“…Aims: Lower limb reconstruction (LLR) has a profound impact on patients, affecting multiple areas of their lives. Many patient-reported outcome measures (PROMs) are employed to assess these impacts; however, there are concerns that they do not adequately capture all outcomes important to patients, and may lack content validity in this context. …”
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Traces of Paleolithic expansion in the Nivkh gene pool based on data on autosomal SNP and Y chromosome polymorphism by V. N. Kharkov, N. A. Kolesnikov, L. V. Valikhova, A. A. Zarubin, A. L. Sukhomyasova, I. Yu. Khitrinskaya, V. A. Stepanov

“…The Nivkhs are a small ethnic group indigenous of the Russian Far East, living in the Khabarovsk Territory and on Sakhalin Island, descending from the ancient inhabitants of these territories. …”
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Exercise-based cardiac rehabilitation for patients with atrial fibrillation receiving catheter ablation: protocol for a feasibility randomised controlled trial (RCT) with embedded... by Gregory Y H Lip, Helen Jones, Mark T Mills, Dhiraj Gupta, Lawrence Foweather, Benjamin JR Buckley, Charlotte Fitzhugh

“…The global prevalence has risen sharply in the past two decades, from 33.3 million to 59 million individuals living with AF, and is associated with stroke, heart failure and mortality. …”
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Food insecurity and the risk of HIV acquisition: findings from population-based surveys in six sub-Saharan African countries (2016–2017) by Danielle Barradas, Nicholus Mutenda, Hetal Patel, Avi J Hakim, Lloyd Mulenga, Sally Findley, Andrea Low, George Rutherford, Sarah Ayton, Elizabeth Gummerson, Amee Schwitters, Rogerio Bonifacio, Mekleet Teferi, James Juma, Claudia Ahpoe, Choice Ginindza, Samuel Biraro, Karam Sachathep, Ahmed Saadani Hassani, Willford Kirungi, Keisha Jackson, Leah Goeke, Neena Philips, Jennifer Ward, Steven Hong

“…Objective To assess the potential bidirectional relationship between food insecurity and HIV infection in sub-Saharan Africa.Design Nationally representative HIV impact assessment household-based surveys.Setting Zambia, Eswatini, Lesotho, Uganda and Tanzania and Namibia.Participants 112 955 survey participants aged 15–59 years with HIV and recency test results.Measures Recent HIV infection (within 6 months) classified using the HIV-1 limited antigen avidity assay, in participants with an unsuppressed viral load (>1000 copies/mL) and no detectable antiretrovirals; severe food insecurity (SFI) defined as having no food in the house ≥three times in the past month.Results Overall, 10.3% of participants lived in households reporting SFI. SFI was most common in urban, woman-headed households, and in people with chronic HIV infection. …”
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The use and subjective experience of sleep apps and their relationship with personality characteristics among young adults by Ståle Pallesen, Ståle Pallesen, Øystein Vedaa, Øystein Vedaa, Erlend Sunde, Erlend Sunde, Anette Harris, Siri Waage, Siri Waage, Ingvild West Saxvig, Jiewen Zhang, Bjørn Bjorvatn, Bjørn Bjorvatn

“…Still, understanding of characteristics of users and the impact of sleep app usage remains limited.MethodsA sample of 940 young adults (18–30 years) living in the UK were recruited from Prolific (online research platform offering researchers access to survey panels) and invited to participate in a survey on the use and experience with sleep apps. …”
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Prevalence of gastrointestinal symptoms after recovery from COVID-19: A questionnaire-based study in the Aseer region by Mohammed Attieh Alzahrani, Khalid Siraj Altalhiyyah, Mohammed Mousa Albariqi, Meshal Ali Alkhayri, Saad Ali Alshahrani, Sultan Saad Alnasser, Nawaf Mohammed Alshehri, Saad Haif Alqahtani, Saud Haif Alqahtani

“…The study population included individuals aged 18 years or older with COVID-19 and living in the Aseer region. The data were collected through a pretested, structured online questionnaire preceded by consent and were used to maintain the confidentiality of the data. …”
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Self-reported determinants for subjective financial distress: a qualitative interview study with German cancer patients by Eva Winkler, Katja Mehlis, Bastian Surmann, Wolfgang Greiner, Andrea Züger, Viktoria Mathies, Sophie Pauge, Luise Richter, Thomas Ernst, Natalja Menold

“…The self-reported determinants can be classified into material (savings, good salary, shared rent through shared living, employed partner, paid-off house, potential financial support from family and friends, work-related specifics, consumer restrictions, out-of-pocket-costs and anticipated financial changes), social (social support from friends and family), systemic (administrative hurdlers and insurance cover) and inner personal determinants (coping strategies, change of attitude, character traits).Conclusion Subjective financial distress depends not only on material but also on social, systemic and inner personal determinants. …”
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Determinant of unmet need for family planning among adolescent and young women in Kenya: multilevel analysis using recent Kenyan demographic health survey by Beyene Sisay Damtew, Hinsermu Bayu Abdi, Beker Ahemed Hussien, Getahun Tiruye, Nafyad Tolossa Urgie, Beniam worku Yigezu, Sifan Ahmed Mohammed, Bezawit Melak Fente

“…Younger women, those in rural areas, and those living in poverty are particularly affected. Addressing this issue requires a comprehensive approach that considers the specific circumstances of these vulnerable populations.…”
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The association of HIV status and depressive symptoms in the Ndlovu Cohort study by Li Xiang Y. den Boer, Karine Scheuermaier, Hugo A. Tempelman, Roos E. Barth, Walter L. J. M. Devillé, Roel A. Coutinho, Diederick E. Grobbee, Francois Venter, Alinda G. Vos-Seda, Kerstin Klipstein-Grobusch

“…Depressive symptoms are common in people living with HIV (PLHIV). Few studies compared depressive symptoms between PLHIV and those without HIV. …”
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Patient participation in free cataract surgery: a cross-sectional study of the low-income elderly in urban China by Bo Qu, Hui Chen, Xuhua Tan, Xiaohang Wu, Haotian Lin, Zhenzhen Liu, Lixia Luo, Bo Zhang, Erping Long, Duoru Lin, Weirong Chen, Yizhi Liu, Haofeng Jiang, Jingjing Chen, Zhuoling Lin, Xiaoyan Li, Jinzhu Tang, Yingfen Lin

“…Patients underwent surgery 61.08±60.15 months (95% CI 56.17 to 66.00) after becoming aware of the cataract, although 66.83% of them reported that their daily lives were influenced by cataracts. Only 21.5% of the respondents underwent physical examinations that included regular eye screening, and only 6.30% were highly educated patients. …”
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