Decoding HIV-associated neurocognitive disorders: a new perspective from multimodal connectomics by Zhongkai Zhou, Wei Wang, Hui Li, Ying Shi, Lingling Zhao, Yibo Lu, Xingchen Wei, Hongjun Li

“…Currently, HIV-associated neurocognitive disorders (HAND) remains one of the major challenges faced by people living with HIV (PLWH). HAND involves the vulnerability of neural circuits caused by synaptic degeneration and abnormal synaptic pruning. …”
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Esophageal Gastrointestinal Stromal Tumor with Rare Intracranial Metastasis by José Carvalho, Margarida Teixeira, Francisco Teixeira Silva, Alexandra Esteves, Carlos Ribeiro, Diana Guerra

“…The rarity of GIST brain metastases is noteworthy, and because of that, there is not enough experience to be certain of the best treatment. Our patient lived for 13 years with excellent disease control with imatinib, but the fact that it does not cross the blood-brain barrier makes it not useful in preventing or treating brain lesions. …”
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East Asian Gene flow bridged by northern coastal populations over past 6000 years by Juncen Liu, Yichen Liu, Yongsheng Zhao, Chao Zhu, Tianyi Wang, Wen Zeng, Bo Sun, Fen Wang, Hui Han, Zhenguang Li, Xiaotian Feng, Peng Cao, Fengshi Luan, Feng Liu, Qingyan Dai, Junfeng Guo, Zimeng Wang, Chengmin Wei, Qiaowei Wei, Ruowei Yang, Weihong Hou, Wanjing Ping, Fan Bai, Bo Miao, Wenjun Wang, Melinda A. Yang, Qiaomei Fu

“…We found that ancestry related to ShanDong populations likely explains the mainland East Asian ancestry observed in post-Yayoi populations from the Japanese archipelago, particularly recent populations who lived in the Ryukyu Islands after ~2800 BP. In the ShanDong region, we observed gene flow from populations to the north and south of this region by at least ~7700 BP, and two waves of gene flow associated with the inland Yellow River populations into the ShanDong region during the DaWenKou cultural period (6000-4600 BP) and in the early dynastic period (3500-1500 BP). …”
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The <i>OsGATA</i> gene family as a promising candidate for applying the CRISPR/Cas genome editing technology to improve the nutritional and yield qualities of rice (<i>Oryza sativa... by E. A. Nesterova, N. A. Shvachko

“…Molecular breeding of rice (Oryza sativa L.) for yield is of great importance for ensuring food security of the population. Living organisms manifest genetically determined responses to environmental factors, including stressors. …”
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Catalase Biomimetic Sensor Based on Metal by Malikova Nurana Nahmad, Gurbanova Lala Maharram, Ali-Zadeh Nahmad Islam, Nagiev Tofik Murtuza, Shokhzod Ulashov, Kurbanova Shaxnoza

“…Chemical reactions in living organisms are carried out with the help of catalysts - enzymes. …”
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Mapping the “catscape” formed by a population of pet cats with outdoor access by Richard Bischof, Nina Rosita Hansen, Øyvind Skarsgard Nyheim, Astrid Kisen, Lillian Prestmoen, Torbjørn Haugaasen

“…Using a citizen science approach, we GPS-tagged 92 pet cats with outdoor access living in a residential area in southern Norway. The resulting position data allowed us to construct both individual home range kernels and a population-level utilization distribution. …”
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The role of fluid friction in streamer formation and biofilm growth by Cornelius Wittig, Michael Wagner, Romain Vallon, Thomas Crouzier, Wouter van der Wijngaart, Harald Horn, Shervin Bagheri

“…Abstract Biofilms constitute one of the most common forms of living matter, playing an increasingly important role in technology, health, and ecology. …”
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A case of kidney graft injury during cesarean section in a pancreas and kidney transplantation recipient by Noriko Aida, Eiji Nishio, Takao Sekiya, Naohiro Aida, Taihei Ito, Takashi Kenmochi, Haruki Nishizawa

“…A 40-year-old pregnant woman (gravida 0, para 0) was referred to our clinic. She had undergone living donor kidney transplantation 11 years earlier and brain-dead donor pancreas transplantation 1 year earlier owing to type 1 diabetes. …”
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The Epidemiology of Hospital-Referred Head Injury in Ardabil City by Esmaeil Farzaneh, Ghasem Fattahzadeh-Ardalani, Vahid Abbasi, Fariba Kahnamouei-aghdam, Behnam Molaei, Elham Iziy, Habib Ojaghi

“…Of all registered cases, 146 (71.6%) were male and the rest of them were female. Most of HT patients lived in Ardabil city (60.8%). The mean age of patients was 22.6 ± 25.9 and most of victims were young. 24.5% of traumatic patients have injuries in severe to critical level (grade 3-4). …”
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A Novel, Cell-Compatible Hyaluronidase Activity Assay Identifies Dextran Sulfates and Other Sulfated Polymeric Hydrocarbons as Potent Inhibitors for CEMIP by Anja Schmaus, Sofia Spataro, Paul Sallmann, Stephanie Möller, Leonardo Scapozza, Marco Prunotto, Jonathan P. Sleeman

“…The hyaluronidase CEMIP requires the presence of living cells for its HA depolymerizing activity. CEMIP is overexpressed in a variety of pathological conditions, and the inhibition of its hyaluronidase activity therefore has therapeutic potential. …”
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Planning Strategies for Increasing the Occupancy Rate of Green Open Space Based on Urban Geographic Data in Macau: An Investigation of Ultra-High-Density Cities by Jitai Li, Fan Lin, Hongcan Cui, Yile Chen, Shuai Yang

“…On the other hand, in order to improve the problem of poor living conditions in the high-density city of Macau, the study proposes to make use of the unutilized Macau Largo space and carry out the optimization and transformation of the Largo space from “gray to green”, so as to release a large amount of green open space and enhance the GOSOR value of the high-density street area of Macau Peninsula.…”
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Laparoscopic Splenectomy to Salvage Renal Transplants from Severe Acute Antibody-Mediated Rejection by Michael Latzko, Sakshi Jasra, Sana Akbar, Harry Sun, Sadanand Palekar

“…She was scheduled to undergo an incompatible 1-1-1 mismatch living related donor kidney transplant. Preoperatively, the patient received plasmapheresis, IVIG, and thymoglobulin. …”
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Barriers Preventing Liver Transplantation in Canadians with HIV Infection – Perceptions of HIV Specialists by Curtis L Cooper, Joanne DeForest, John Gill, Richard Lalonde, on behalf of the Canadian HIV Trials Network (CTN) Co-Infection Core Group

“…Liver transplantation is currently largely unavailable to those living with HIV in Canada. Understanding the obstacles to this procedure is the first step to increasing access. …”
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Effects of a Multidisciplinary Educational Rehabilitative Intervention in Breast Cancer Survivors: The Role of Body Image on Quality of Life Outcomes by Giovanni Morone, Marco Iosa, Augusto Fusco, Antonella Scappaticci, Maria Rosaria Alcuri, Vincenzo Maria Saraceni, Stefano Paolucci, Teresa Paolucci

“…In breast cancer survivors, own body image may change due to physical and psychological reasons, worsening women’s living. The aim of the study was to investigate whether body image may affect the functional and quality of life outcomes after a multidisciplinary and educational rehabilitative intervention in sixty women with primary nonmetastatic breast cancer who have undergone conservative surgery. …”
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Adeno-associated virus-based gene therapy for hemophilia–addressing the gaps by Wolfgang Miesbach, Paul Batty, Pratima Chowdary, Sylvia Fong, Radoslaw Kaczmarek, Frank W.G. Leebeek, Brian Long, Johnny Mahlangu, Mike Makris, Glenn F. Pierce, Steven W. Pipe, Alok Srivastava, Jan Voorberg, Flora Peyvandi

“…With 3 gene therapies recently approved, this approach shows promise in transforming the lives of individuals with hemophilia. However, the complexity of gene therapy and the lack of standardization of methods in different components of this therapy can lead to unique challenges for clinical implementation. …”
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Assessment of Morphological Changes in Breast Cancer Cells Following X-Ray Radiation Utilizing Digital Holographic Microscopy by Zeinab Hormozi-Moghaddam, Seyedeh Mona Taheri, Reza Paydar, Ali Neshasteh-Riz, Vahideh Farzam Rad, Mohadeseh Shaghaghi

“… Purpose: Digital holographic microscopy, being a label-free and entirely non-invasive technique, proficiently facilitates the quantitative assessment of morphological alterations in living cells. The primary objective of this investigation is to scrutinize the capability of a digital holographic microscope in assessing the morphological transformations of cancer cells exposed to X-ray radiation. …”
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Healthcare access, attitudes and behaviours among Navajo adults during the COVID-19 pandemic: a cross-sectional study by Robin B Harris, Carmenlita Chief, Heidi E Brown, Rachelle L Begay, Priscilla R Sanderson, Breanna Lameman

“…Discussion themes revealed perceived disruptions of healthcare needs with acknowledgement that healthcare providers were supportive throughout the Navajo Nation quarantine.Conclusion Presence of comorbidities and living in multigenerational homes do not explain the disproportionate effects of COVID-19 among American Indian communities. …”
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Evaluating GEMS HCHO Retrievals With TROPOMI Product, Pandora Observations, and GEOS‐Chem Simulations by Weitao Fu, Lei Zhu, Hyeong‐Ahn Kwon, Rokjin J. Park, Gitaek T. Lee, Isabelle DeSmedt, Song Liu, Xicheng Li, Yuyang Chen, Dongchuan Pu, Juan Li, Xiaoxing Zuo, Peng Zhang, Yali Li, Zhuoxian Yan, Xue Zhang, Jiaming Zhang, Xingyi Wu, Huizhong Shen, Jianhuai Ye, Chen Wang, Tzung‐May Fu, Xin Yang

“…Abstract Satellite column formaldehyde (HCHO) is an indicator of regional volatile organic compounds (VOC) emissions as HCHO is a short‐lived intermediate oxidation product. The Geostationary Environment Monitoring Spectrometer (GEMS), launched in 2020, is the first geostationary satellite to monitor hourly HCHO. …”
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Study of the Potential Endocrine-Disrupting Effects of Phenylurea Compounds on Neurohypophysis Cells In Vitro by Krisztián Sepp, Zsolt Molnár, Anna M. László, Tünde Alapi, László Tóth, Andrea Serester, Zsuzsanna Valkusz, Márta Gálfi, Marianna Radács

“…If they modify the adaptation of living organisms as direct (e.g., by altering hormone regulation, membrane functions) and/or indirect (e.g., cell transformation mechanisms) factors, they are classified as EDC. …”
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Assessing Methods to Measure Stem Diameter at Breast Height with High Pulse Density Helicopter Laser Scanning by Matthew J. Sumnall, Ivan Raigosa-Garcia, David R. Carter, Timothy J. Albaugh, Otávio C. Campoe, Rafael A. Rubilar, Bart Alexander, Christopher W. Cohrs, Rachel L. Cook

“…Stem horizontal size was estimated every 25 cm below the living crown, and a cubic spline was used to estimate where there were gaps. …”
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