Role of Probiotics in the Management of Patients with Ulcerative Colitis and Pouchitis by Francesca Bernardi, Fabrizio Fanizzi, Tommaso Lorenzo Parigi, Alessandra Zilli, Mariangela Allocca, Federica Furfaro, Laurent Peyrin-Biroulet, Silvio Danese, Ferdinando D’Amico

“…Future directions should prioritize advancing research to optimize probiotic therapies and establish personalized approaches based on individual microbiome profiles, highlighting their significant potential as a promising treatment strategy for pouchitis.…”
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Lipid Antigens: Revealing the Hidden Players in Adaptive Immune Responses by Tamana Eskandari, Yasamin Eivazzadeh, Fatemeh Khaleghinia, Fatemeh Kashi, Valentyn Oksenych, Dariush Haghmorad

“…In the years to come, continued research efforts are needed to uncover its underlying biological mechanisms and to exploit the full potential of therapies directed against lipid antigens.…”
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Peak steps to measure ‘‘capacity for activity’’: Actigraphy in the ADAPT registry with oral treprostinil by Daniel Lachant, DO, James Gagermeier, MD, Scott Seaman, PhD, Andrew Wang, MPH, Meredith Broderick, PharmD, JD, R. James White, MD, PhD

“…Summary actigraphy measures (total daily steps or activity time) have not been shown to increase after adding therapies in patients with PAH. We developed a novel treatment responsive metric, Peak Steps, to measure the ‘capacity for movement’ in patients with PAH. …”
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Antin-diabetic cognitive dysfunction effects and underpinning mechanisms of phytogenic bioactive peptides: a review by Xiaoli Liu, Xiaoli Liu, Shenglian Mao, Shenglian Mao, Yuxue Yuan, Yuxue Yuan, Zilin Wang, Zilin Wang, Yang Tian, Yang Tian, Yang Tian, Liang Tao, Liang Tao, Jiahe Dai, Jiahe Dai

“…Therefore, there is an urgent need to find safe and effective alternative therapies. Accumulating evidence suggests that phytogenic bioactive peptides play an important role in the regulation of cognitive dysfunction in diabetes. …”
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THE TRAINING OF SOCIAL COMPETENCE IN AGGRESSIVE PREADOLESCENTS by SAVCA Lucia, NANDOR Nemes Madoxa

“…In the given study, we reflected the content of the training program for social competence (CS), created by us, which included the CASEL model, but also effective techniques from different therapies. 28 preadolescents participated in the formative group: 14 students in GE and 14 students in GC. 13 sessions lasting 90 min were held once a week. …”
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Anticancer Ribosomally Synthesized and Post-Translationally Modified Peptides from Plants: Structures, Therapeutic Potential, and Future Directions by Hyeon-Jeong Hwang, Youngsang Nam, Chanhee Jang, Eun La Kim, Eun Seo Jang, Yeo Jin Lee, Seoung Rak Lee

“…These findings pave the way for further exploration of plant RiPPs, emphasizing their role in addressing the ongoing challenges in oncology and enhancing the repertoire of effective anticancer therapies.…”
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Utilizing Feature Selection Techniques for AI-Driven Tumor Subtype Classification: Enhancing Precision in Cancer Diagnostics by Jihan Wang, Zhengxiang Zhang, Yangyang Wang

“…The integration of multi-omics data and ML algorithms facilitates a more comprehensive understanding of tumor heterogeneity, advancing both diagnostics and personalized therapies. However, challenges such as ensuring data quality, mitigating overfitting, and addressing scalability remain critical limitations of these methods. …”
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HPRNA: Predicting synergistic drug combinations for angina pectoris based on human pathway relationship network algorithm. by Mengyao Zhou, Mengfan Xu, Xiangling Zhang, Xiaochun Xing, Yang Li, Guanghui Wang, Guiying Yan

“…Over the years, synergistic drug combinations therapies have attracted widespread attention due to its advantages of overcoming drug resistance, increasing treatment efficacy and decreasing toxicity. …”
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Latent Inflammation and Insulin Resistance in Adipose Tissue by I. S. Stafeev, A. V. Vorotnikov, E. I. Ratner, M. Y. Menshikov, Ye. V. Parfyonova

“…Finally, we discuss perspectives for anti-inflammatory therapies in treating the metabolic diseases.…”
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MicroRNAs in pancreatic cancer drug resistance: mechanisms and therapeutic potential by Fangying Dong, Jing Zhou, Yijie Wu, Zhaofeng Gao, Weiwei Li, Zhengwei Song

“…Pancreatic cancer (PC) remains one of the most lethal malignancies, primarily due to its intrinsic resistance to conventional therapies. MicroRNAs (miRNAs), key regulators of gene expression, have been identified as crucial modulators of drug resistance mechanisms in this cancer type. …”
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Scoping review of molecular biomarkers associated with fatigue, stress, and depression in stroke survivors: A protocol. by Tarynn Potter, Nisal Gange, Eliza Whiteside, Prajwal Gyawali

“…The investigation of molecular biomarkers associated with post-stroke stress, fatigue, and depression may shed light on the relationships between comorbidities and also contribute to the development of novel diagnostics and therapies. Several biomarkers have been identified for stress, depression, and fatigue, some of which are specific to stroke survivors. …”
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Therapeutic application and potential mechanism of plant-derived extracellular vesicles in inflammatory bowel disease by Jinling Li, Ting Luo, Dou Wang, Yao Zhao, Yuanxiang Jin, Guiling Yang, Xin Zhang

“…An increasing number of studies have confirmed that PDEVs can be a potential treatment of inflammatory bowel disease (IBD) and can, to some extent, compensate for the limitations of existing therapies. Aim of review: This review summarizes the recent advances and potential mechanisms underlying PDEVs obtained from different sources to alleviate IBD. …”
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State Anxiety Inventory Score Among Students With Final Assignment by Ario Imandiri, Erlinda Widyastuti, Arijanto Jonosewojo

“…Those score were then being used as preliminary data to decide the next step of the study which are giving acupuncture therapies to those students with high score of anxiety.  …”
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HIV and the Gut Microbiota, Partners in Crime: Breaking the Vicious Cycle to Unearth New Therapeutic Targets by Kishanda Vyboh, Mohammad-Ali Jenabian, Vikram Mehraj, Jean-Pierre Routy

“…Understanding this self-perpetuating cycle could be a key element in developing new therapies aimed at the gut microbiota and its fallout after infection.…”
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The Immune Response and Its Therapeutic Modulation in Bronchiectasis by Massoud Daheshia, James D. Prahl, Jacob J. Carmichael, John S. Parrish, Gilbert Seda

“…Furthermore, the potential link(s) between an ongoing immune response and structural alterations accompanying the disease and the success of therapies that can modulate the nature and extent of immune response in BC are elaborated upon.…”
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Intravenous γ Globulin for Intractable Abdominal Pain due to IgA Vasculitis by George Naifa, George Totikidis, Sonia Alexiadou, Christina Kolona, Elpis Mantadakis

“…Given the toxicity and/or need for long-term administration of other second-line immunosuppressive therapies in corticosteroid-resistant IgA vasculitis, such as rituximab, cyclosporine, cyclophosphamide, azathioprine, or colchicine, we propose that IVIg may be a useful and safe treatment option, although randomized controlled clinical trials are needed in order to clarify its role in the treatment of abdominal pain in IgA vasculitis.…”
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Promising Markers in the Context of Mesenchymal Stem/Stromal Cells Subpopulations with Unique Properties by Agnieszka Smolinska, Aleksandra Bzinkowska, Paulina Rybkowska, Magdalena Chodkowska, Anna Sarnowska

“…Even though the collected information would allow for better targeting of specific subpopulations in regenerative medicine to increase the effectiveness of MSC-based therapies.…”
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Using Cell-Based Strategies to Break the Link between Bronchopulmonary Dysplasia and the Development of Chronic Lung Disease in Later Life by Megan O'Reilly, Bernard Thébaud

“…This paper summarizes the long-term pulmonary outcomes of preterm birth and BPD and discusses the recent advances of cell-based therapies for lung diseases, with a particular focus on BPD and COPD.…”
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Unveiling the mechanism of action of a novel natural dual inhibitor of SARS-CoV-2 Mpro and PLpro with molecular dynamics simulations by Xiaoxia Gu, Xiaotian Zhang, Xueke Zhang, Xinyu Wang, Weiguang Sun, Yonghui Zhang, Zhengxi Hu

“…Given the conservation of Mpro and PLpro, sydowiol B and violaceol I are promising leads for designing and developing anti-coronavirus therapies. Graphical Abstract…”
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Sitagliptin: a potential drug for the treatment of COVID-19? by Bardaweel Sanaa K., Hajjo Rima, Sabbah Dima A.

“…We conclude that sitagliptin may be beneficial for the treatment of COVID-19 disease, either as monotherapy or in combination with other therapies, especially for diabetic patients and patients with pre-existing cardiovascular conditions who are already at higher risk of COVID-19 mortality.…”
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