Metastatic Bladder Cancer Presenting with Persistent Hematuria in Young Man with Cystic Fibrosis by Premal Patel, Harvey R. Rabin, Michael M. Vickers, Michael D. Parkins

“…This case illustrates how investigations to rule out malignancy are warranted in those CF patients not responding to therapies directed towards presumptive diagnoses.…”
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Role of T Lymphocytes in Type 2 Diabetes and Diabetes-Associated Inflammation by Chang Xia, Xiaoquan Rao, Jixin Zhong

“…We will discuss the available effect of T cells subsets in adaptive immune system associated with the procession of T2DM, which may unveil several potential strategies that could provide successful therapies in the future.…”
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Diagnosis and Management of Interstitial Lung Disease in Patients with Connective Tissue Diseases by Matthew Koslow, Mehrnaz Maleki-Fischbach, Rebecca C. Keith

“…In the absence of guidelines regarding how CTD-ILDs should be treated, clinicians face difficult decisions on when to use immunosuppressant and anti-fibrotic therapies. The importance of a multidisciplinary and individualized approach to the diagnosis and management of CTD-ILD is highlighted in the three case studies that we describe in this article.…”
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The effect of exercise on depression and gut microbiota: Possible mechanisms by Mingchen Yao, Yaqi Qu, Yalin Zheng, Hao Guo

“…Additionally, we reviewed literature on the effects of exercise on depression at different intensities, types, and durations to provide a reference for future exercise-based therapies for depression.…”
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Cognitive Behavioral Psychotherapies: History and Development by M. Hakan Türkçapar, A. Emre Sargın

“…Cognitive behavioral therapies are one of the most leading theories between current psychotherapies. …”
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Microtubule inhibition as a proposed mechanism for the anthelmintic effect of phytochemicals isolated from Cicerbita alpina by Mark James Horgan, Ines Sigg, Ioanna Poulopoulou, Francisco J. Rodriguez-Mejias, Eva Albertini, Pietro Fusani, Florian Fischer, Eftychia Martinidou, Daniela Schuster, Stefan Martens, Pidder Jansen Dürr, Matthias Gauly, Hermann Stuppner, Alexander Weiss, Veronika Temml, Bianka Siewert

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Characterization of Somatic Mutations in Malaysian Luminal Breast Cancer by Yock Ping Chow, Ryia Illani Mohd Yunos, Isa Mohd Rose, Norlia Abdullah, Rohaizak Muhammad, Shahrun Niza Abdullah Suhaimi, Saladina Jaszle Jasmin, Norshahidah Mahamad Nadzir, Nurul-Syakima Ab Mutalib, Rahman Jamal

“…To date, other than hormonal and anti-HER2 therapies (e.g. tamoxifen, aromatase inhibitor, trastuzumab), no other targeted therapies have been approved by FDA for luminal breast cancer. …”
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Challenges in managing osteogenesis imperfecta in a resource-limited setting: a case report by Ssekabembe Richard, Natumanya Robert, Vanusa Da Consolação Sambo, Abonga Daniel, Okidi Ronald

“…Diagnosis is usually based on clinical presentation and low bone mineral density scores, while treatment involves a multidisciplinary approach using medical therapies such as bisphosphonates, vitamin C, and pamidronate. …”
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Looking beyond the ER, PR, and HER2: what’s new in the ARsenal for combating breast cancer? by Tryambak Pratap Srivastava, Ruby Dhar, Subhradip Karmakar

“…This intricate interplay is further complicated by the presence of constitutively expressed AR splice variants (AR-Vs) that drive resistance to AR-targeting therapies through structural rearrangements in the domains and activation of aberrant signaling pathways. …”
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Macrophage Migration Inhibitory Factor in Fetoplacental Tissues from Preeclamptic Pregnancies with or without Fetal Growth Restriction by Simona Cardaropoli, Luana Paulesu, Roberta Romagnoli, Francesca Ietta, Daniela Marzioni, Mario Castellucci, Alessandro Rolfo, Elena Vasario, Ettore Piccoli, Tullia Todros

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Diabetes Treatment with Dapagliflozin and Its Combinations: Insights from Clinical Practice by Akshay Bafna, Ajit Mehta, Rajeev Garg, Jayagopal Pathiyil Balagopalan, Rajesh Rajput, Nitin Zalte, Preethi Naik, Amarnath Sugumaran, Senthilnathan Mohanasundaram

“…Abstract Objective: To evaluate the perception of clinicians about the association of heart failure (HF) and type 2 diabetes mellitus (T2DM) and the utilization of dapagliflozin-based combination therapies for cardiorenal protection in Indian patients with T2DM. …”
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Patients’ preferences on atopic dermatitis skincare and social media use: a qualitative study by Roxana Mazilu, Stefanie Ziehfreund, Stephan Traidl, Alexander Zink

“…Furthermore, female patients express interest in complementary and alternative therapies as part of an integrative therapeutical approach. …”
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Loss of Sirtuin 7 impairs cell motility and proliferation and enhances S-phase cell arrest after 5-fluorouracil treatment in head and neck cancer by Marta Halasa, Syeda Afshan, Anna Wawruszak, Agata Borkowska, Klaudia Brodaczewska, Alicja Przybyszewska-Podstawka, Joanna Kalafut, Marzena Baran, Adolfo Rivero-Müller, Andrzej Stepulak, Matthias Nees

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The Link Between Venous and Arterial Thrombosis: Is There a Role for Endothelial Dysfunction? by Marco Paolo Donadini, Francesca Calcaterra, Erica Romualdi, Roberta Ciceri, Assunta Cancellara, Corrado Lodigiani, Monica Bacci, Silvia Della Bella, Walter Ageno, Domenico Mavilio

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Los olvidados: Non-BRCA variants associated with Hereditary breast cancer in Mexican population by Dione Aguilar, María Lourdes Garza-Rodríguez, Carolina Elizabeth Muñiz-Garza, Fernando Alcorta Nuñez, Cynthia Mayte Villarreal-Garza, Oscar Vidal-Gutiérrez, Diana Cristina Pérez-Ibave, Carlos Horacio Burciaga-Flores

“…HR patient carriers are potential targets of iPARP therapies. The optimal approach to cancer treatment for non-BRCA mutation carriers warrants further investigation to develop newer therapies.…”
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Inhibition of TFF3 synergizes with c-MET inhibitors to decrease the CSC-like phenotype and metastatic burden in ER+HER2+ mammary carcinoma by Chuyu He, Xuejuan Wang, Yi-Shiou Chiou, Basappa Basappa, Tao Zhu, Vijay Pandey, Peter E. Lobie

“…Abstract The interaction between HER2 and ERα signaling pathways contributes to resistance to anti-estrogen and HER2-targeted therapies, presenting substantial treatment challenges in ER-positive (ER+) HER2-positive (HER2+) mammary carcinoma (MC). …”
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RNA sequence analysis landscape: A comprehensive review of task types, databases, datasets, word embedding methods, and language models by Muhammad Nabeel Asim, Muhammad Ali Ibrahim, Tayyaba Asif, Andreas Dengel

“…Furthermore, researchers are harnessing RNA's therapeutic potential for transforming traditional treatment paradigms into personalized therapies through the development of RNA-based drugs and gene therapies. …”
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Human endometrial stem cell-derived small extracellular vesicles enhance neurite outgrowth and peripheral nerve regeneration through activating the PI3K/AKT signaling pathway by Mojdeh Salehi Namini, Nima Beheshtizadeh, Somayeh Ebrahimi-Barough, Jafar Ai

“…Abstract Nowadays, extracellular vesicles (EVs) such as exosomes participate in cell-cell communication and gain attention as a new approach for cell-free therapies. Recently, various studies have demonstrated the therapeutic ability of exosomes, while the biological effect of human endometrial stem cell (hEnSC)-derived small EVs such as exosomes is still unclear. …”
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Modulation of Cognition: The Role of Gnidia glauca on Spatial Learning and Memory Retention in High-Fat Diet-Induced Obese Rats by Wycliffe Makori Arika, Cromwell Mwiti Kibiti, Joan Murugi Njagi, Mathew Piero Ngugi

“…There are limited effective therapies for addressing cognitive deficits. Thus, it is important to identify additional and alternative therapies. …”
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Invasive Aspergillosis in the Intensive Care Unit by Anna Zubovskaia, Jose A. Vazquez

“…Invasive aspergillosis (IA) is a fungal infection, which has traditionally been associated with neutropenia and immunosuppressive therapies. Our understanding of invasive aspergillosis has been evolving and, in the past few decades, IA among ICU patients has been recognized as a common infection and has become more widely recognized. …”
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