Anti-cancer immunotherapy-related cardiotoxicity: preventable and treatable by Wu Helena T., Hsu Vanessa, Win Shwe, Xing Yan

“…Despite their success, these therapies are associated with immune-related adverse events including rare but severe immunotherapy-related cardiotoxicities. …”
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Psoriatic arthritis: An up to date overview by Simon Hackett, Laura Coates

“…Therapies have shown that robust treatment in patients, achieving tight disease control, improves outcomes and overall quality of life. …”
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Nicotine Replacement Combined with a Novel Compound (ProBAN) for Smoking Cessation: A Pilot Study by Richard Leigh, Norman M Viner, Gerard Cox, Jeffrey W Balon, Douglas MC Wilson, Denise O’Shaughnessy, Corinne Walker, Gerry Brosky, Malcolm R Sears

“…BACKGROUND: Smoking cessation rates with available pharmacological therapies remain suboptimal. Anecdotal observations with a combination of sublingual pralidoxime and ipratropium (ProBAN) suggested that these agents in combination with nicotine gum improved quit rates.…”
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Adrenaline Injection Plus Argon Plasma Coagulation versus Adrenaline Injection Plus Hemoclips for Treating High-Risk Bleeding Peptic Ulcers: A Prospective, Randomized Trial by Seyed Alireza Taghavi, Seyed Mohammad Soleimani, Seyed Mohammad Kazem Hosseini-Asl, Ahad Eshraghian, Hajar Eghbali, Seyed Mohsen Dehghani, Bita Ahmadpour, Mehdi Saberifiroozi

“…BACKGROUND/OBJECTIVE: Several combination endoscopic therapies are currently in use. The present study aimed to compare argon plasma coagulation (APC) + adrenaline injection (AI) with hemoclips + AI for the treatment of high-risk bleeding peptic ulcers.…”
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Morphology of Helicobacter pylori as a result of peptidoglycan and cytoskeleton rearrangements by Paweł Krzyżek, Grażyna Gościniak

“…In addition, the existence of proteins associated with modifications of H. pylori morphology as potential targets in therapies reducing the virulence of this bacterium has been suggested.…”
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Unraveling the Effect of Immunogenicity on the PK/PD, Efficacy, and Safety of Therapeutic Proteins by Alison Smith, Hugh Manoli, Stacey Jaw, Kimberley Frutoz, Alan L. Epstein, Leslie A. Khawli, Frank-Peter Theil

“…Biologics have emerged as a powerful and diverse class of molecular and cell-based therapies that are capable of replacing enzymes, editing genomes, targeting tumors, and more. …”
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Mesenchymal Stem Cells as Immunomodulators in a Vascularized Composite Allotransplantation by Yur-Ren Kuo, Chien-Chang Chen, Shigeru Goto, Pao-Yuan Lin, Fu-Chan Wei, Chao-Long Chen

“…In this paper, we summarize the current understanding of immunomodulation achieved by MSC therapies and introduce a possible outline for future clinical applications in VCA.…”
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Atopic dermatitis - the review by Joanna Wrona, Aleksandra Kaźmierczyk, Jędrzej Kęsik, Daria Madycka, Kacper Michta, Małgorzata Słaboń, Aleksandra Wójcik, Karol Stępniak, Wiktor Telega, Kinga Wnuczek

“…Management strategies include patient education, topical therapies (e.g., corticosteroids, calcineurin inhibitors, crisaborole, and tapinarof), systemic treatments like dupilumab and methotrexate, and phototherapy for refractory cases. …”
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Bone Marrow Stem Cell as a Potential Treatment for Diabetes by Ming Li, Susumu Ikehara

“…However, these therapies fail to maintain blood glucose levels in the normal range all the time. …”
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Neuroplasticity in Alzheimer's disease: a therapeutic alternative at the molecular level by Noel Jesús Niebla Gómez, Rodolfo Javier Rivero Morey, Víctor René Navarro Machado, Mariangel González León, Amanda Martínez Pérez

“…The neuroplasticity mechanisms of the organism form the basis of dissimilar therapies that seek to potentiate such effects to achieve relative improvement in a large number of neurodegenerative diseases. …”
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Up-to-Date Tailored Systemic Treatment in Pancreatic Ductal Adenocarcinoma by Caroline Y. K. Fong, Emma Burke, David Cunningham, Naureen Starling

“…Research has since focussed on understanding the role and interplay between various components of the desmoplastic stroma and tumour microenvironment, in addition to developing targeted therapies based on molecular features to improve the prognosis associated with this malignancy. …”
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Targeting estrogen-regulated system xc − promotes ferroptosis and endocrine sensitivity of ER+ breast cancer by Jiawei Cao, Tong Zhou, Tao Wu, Rixu Lin, Ju Huang, Dejin Shi, Jiawei Yu, Yinrui Ren, Changrui Qian, Licai He, Guang Wu, Zhixiong Dong, Shaofei Yuan, Haihua Gu

“…Abstract Estrogen receptor positive (ER+) breast cancer accounts for approximately 70% of cases. Endocrine therapies targeting estrogen are the first line therapies for ER+ breast cancer. …”
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Tumor hypoxia evidences the differential regulation of Mdm2-p53 axis by PTEN in tumor derived vs. normal endothelial cells by Kinga Wilkus-Adamczyk, Klaudia Brodaczewska, Claudine Kieda

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Successful Treatment of Annular Atrophic Lichen Planus With Adalimumab by Joe Khodeir, Paul Ohanian, Marielena Ohanian

“…ABSTRACT Adalimumab may be an effective treatment for resistant annular atrophic lichen planus, especially in patients with prior treatment failures and contraindications to other systemic therapies. This case underscores the need for exploring systemic options in challenging cases of this rare lichen planus variant.…”
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Clostridioides difficile infection: a changing treatment paradigm by Yousif Al Naser, Marriam AlGashami, Layth Aljashaami

“…The horizon of CDI treatment also features promising therapies such as SER-109 and Rebyota, epitomising the evolving paradigm. …”
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Disturbances in the Mechanism of Apoptosis as One of the Causes of the Development of Cancer Diseases by Paweł Rusin, Karolina Jabłońska

“…The mechanisms responsible for apoptosis regulation are impaired, what eliminates the effects of therapies aimed at initiating this type of cell death. …”
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SARS-CoV-2 drug resistance and therapeutic approaches by Sania Batool, Santosh Chokkakula, Ju Hwan Jeong, Yun Hee Baek, Min-Suk Song

“…By examining the complex interactions between the virus and its host, the review advocates for a multifaceted approach, including combination therapies, targeted drug development, and continuous surveillance of viral mutations. …”
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The Role of Gut Microbiota Modification in Nonalcoholic Fatty Liver Disease Treatment Strategies by Hessam Yaghmaei, Amirhossein Bahanesteh, Masood Soltanipur, Sobhan Takaloo, Mahdi Rezaei, Seyed Davar Siadat

“…In addition to dietary interventions and lifestyle modifications, GM modification-based therapies are of interest. These therapies include probiotics, synbiotics, fecal microbiota transplantation (FMT), and next-generation probiotics. …”
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Antioxidant Vitamins in the Prevention of Atrial Fibrillation: What Is the Evidence? by Sonia Rasoli, Nicholaos Kakouros, Leanne Harling, Philemon Gukop, Manish Soni, Thanos Athanasiou, Antonios Kourliouros

“…Atrial fibrillation (AF) is the most common sustained arrhythmia that is associated with significant morbidity and mortality. Current available therapies remain inadequate in symptom control and secondary prevention and are often associated with significant side effects. …”
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Modified Scaffolds With Magnetic Nanoparticles in Periodontal Tissue Regeneration by Dulce Araceli Guzman‐Rocha, Benjamin Aranda‐Herrera, Laura Susana Acosta Torres, Ma. Concepción Arenas‐Arrocena, Rene Garcia‐Contreras

“…Metal oxide nanoparticles, like Magnetic nanoparticles (MNPs), offer unique physicochemical properties ideal for biomedical applications, advancing diagnostics, therapies, tissue engineering and imaging technologies in medicine. …”
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