Skin Matters: Identifying Pain Mechanisms and Predicting Treatment Outcomes by Edward A. Shipton

“…There is potential for these findings to predict treatment outcomes in clinical practice and to develop new therapies for different pain conditions. These findings should enhance the physician's ability to evaluate and treat diverse types of pain.…”
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Love Addiction - Current Diagnostic and Therapeutic Paradigms in Clinical Psychology. by Marilena Giovanna Maglia, Ines Lanzafame, Maria C Quattropani, Pasquale Caponnetto

“… # Conclusions Group psychotherapy has proved to be a valid alternative, in fact the scientific landscape suggests that most group therapies are successful because these dynamics involve the reward and attachment systems in the brain in most subjects. …”
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Surgical modalities in the treatment of vitiligo by R. Vignesh Narayan, Vishal Thakur

“…Vitiligo presents a challenge not only in its medical management but also in its impact on patients’ psychosocial well-being. While medical therapies can halt disease progression, achieving repigmentation, especially in challenging areas, remains a hurdle. …”
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Extracellular vesicles—a new player in the development of urinary bladder cancer by Damian Kasiński, Kamil Szeliski, Tomasz Drewa, Marta Pokrywczyńska

“…An in-depth understanding of the role EVs play in the development of urinary bladder cancer is crucial for the development of future anticancer therapies.…”
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Harnessing nanotechnology for enhanced epilepsy management by V. Manasa, J. Joysa Ruby, Himadri Priya Gogoi, S. Vignesh, P. H. Anjaneya, Akhil

“…Prospects include nanodroplet drug delivery, neural repair with nanomaterials, and highly individualized epilepsy therapies. These innovations could significantly improve traditional treatments, patient outcomes, and quality of life, underscoring the importance of collaboration among healthcare providers, scientists, and technologists to maximize their potential. …”
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Muscle-Specific Tyrosine Kinase-Associated Myasthenia Gravis: A Neuromuscular Surprise by Hassam Ali, Rahul Pamarthy, Nayab Ahsan, null WashmaAwan, Shiza Sarfraz

“…It responds inconsistently to steroids, but plasma exchange and immunosuppressive therapies have shown promising results. We report a case of a 49-year-old female who presented with acute hypoxic respiratory failure. …”
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Pan-inhibition of super-enhancer-driven oncogenic transcription by next-generation synthetic ecteinascidins yields potent anti-cancer activity by Max Cigrang, Julian Obid, Maguelone Nogaret, Léane Seno, Tao Ye, Guillaume Davidson, Philippe Catez, Pietro Berico, Clara Capelli, Clara Marechal, Amélie Zachayus, Clémence Elly, Marie Jose Guillen Navarro, Marta Martinez Diez, Gema Santamaria Nunez, Tsai-Kun Li, Emmanuel Compe, Pablo Avilés, Irwin Davidson, Jean-Marc Egly, Carmen Cuevas, Frédéric Coin

“…Consequently, these compounds exhibit cytotoxic activity across distinct subpopulations of metastatic melanoma cells and inhibit tumor proliferation, including those resistant to current therapies. These findings extend to other cancers, like small cell lung cancer, recently approved for ecteinascidin-based treatment. …”
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Association between HMGB1 and COPD: A Systematic Review by Sebastiano Gangemi, Marco Casciaro, Giovanni Trapani, Sebastiano Quartuccio, Michele Navarra, Giovanni Pioggia, Egidio Imbalzano

“…Current anti-inflammatory therapies are poorly effective in maintaining lung function and symptoms of COPD. …”
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Inactivation of Zika Virus with Hydroxypropyl-Beta-Cyclodextrin by Cory R. Hewitt, Nicholas J. Wixon, Arthur Gallegos, You Zhou, Victor C. Huber, M. Scott Killian

“…To date, there are no available FDA-approved therapies or vaccines for the specific treatment or prevention of ZIKV infection. …”
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The potential of Dayak tribal herbal leaves as an anti-breast cancer agent: In silico approach by Kellik Setiawan Volta, Affan Ali Murtadlo Ahmad, Nur Muhammad Ansori Arif, Dhea Kharisma Viol, Dayu Rahma Turista Dora

“…Breast cancer is one of the leading causes of mortality among women worldwide, prompting the exploration of alternative, natural therapies. This study examines the anti-breast cancer potential of traditional herbal plants used by the Dayak tribe, particularly Kleinhovia hospita Linn. …”
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Guidance Cue Netrin-1 and the Regulation of Inflammation in Acute and Chronic Kidney Disease by Punithavathi Ranganathan, Riyaz Mohamed, Calpurnia Jayakumar, Ganesan Ramesh

“…Despite improved understanding, there are no effective therapies available to treat AKI. A large body of evidence strongly suggests that ischemia reperfusion injury is an inflammatory disease mediated by both adaptive and innate immune systems. …”
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Systems immunology integrates the complex endotypes of recessive dystrophic epidermolysis bullosa by Nell Hirt, Enzo Manchon, Qian Chen, Clara Delaroque, Aurelien Corneau, Patrice Hemon, Safaa Saker-Delye, Pauline Bataille, Jean-David Bouaziz, Emmanuelle Bourrat, Alain Hovnanian, Helene Le Buanec, Fawzi Aoudjit, Hicham El Costa, Nabila Jabrane-Ferrat, Reem Al-Daccak

“…By characterising the phenotype-endotype association in RDEB adults, our study lays the groundwork for translational interventions that could by lessening inflammation, alleviate the everlasting suffering of RDEB patients, while awaiting curative genetic therapies.…”
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Biochemistry of Bacterial Biofilm: Insights into Antibiotic Resistance Mechanisms and Therapeutic Intervention by Kashish Azeem, Sadaf Fatima, Asghar Ali, Ayesha Ubaid, Fohad Mabood Husain, Mohammad Abid

“…The exploration of combination therapies, involving antimicrobial agents, biofilm-disrupting enzymes, and immunomodulators, is emphasized to enhance the efficacy of existing treatments and overcome biofilm resilience.…”
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Design of a Reconfigurable Robotic System for Flexoextension Fitted to Hand Fingers Size by J. Felipe Aguilar-Pereyra, Eduardo Castillo-Castaneda

“…Due to the growing demand for assistance in rehabilitation therapies for hand movements, a robotic system is proposed to mobilize the hand fingers in flexion and extension exercises. …”
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Applications of Amniotic Membrane and Fluid in Stem Cell Biology and Regenerative Medicine by Kerry Rennie, Andrée Gruslin, Markus Hengstschläger, Duanqing Pei, Jinglei Cai, Toshio Nikaido, Mahmud Bani-Yaghoub

“…Much progress has been made since the discovery of AM and AF cells with stem cell characteristics nearly a decade ago, but there remain a number of problematic issues stemming from the inherent heterogeneity of these cells as well as inconsistencies in isolation and culturing methods which must be addressed to advance the field towards the development of cell-based therapies. Here, we provide an overview of the recent progress and future perspectives in the use of AM- and AF-derived cells for therapeutic applications.…”
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A Series of 35 Cutaneous Infections Caused by Mycobacterium marinum in Han Chinese Population by Wenjie Chen, Fangfang Bao, Qing Pan, Tingting Liu, Xiaotong Xue, Hong Liu, Furen Zhang

“…The aim of this study was to evaluate the differences in time to treatment among patients with different types of skin lesions and who were treated with single or multidrug therapies. In addition, the clinical characteristics of M. marinum infection were explored and the mechanism of the host immune responses was investigated. …”
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Targeting gut microbiota in osteoporosis: impact of the microbial-based functional food ingredients by Pauline Duffuler, Khushwant S. Bhullar, Jianping Wu

“…Despite promising initial results, microbial-based therapies are still under investigation. Moreover, additional animal studies and clinical trials are needed to understand the interactions between gut microbiota and bone metabolism before further applications.…”
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Study on Association of Pentraxin 3 and Diabetic Nephropathy in a Rat Model by Xuehai Chen, Jiao Luo, Minmin Wu, Zhuo Pan, Yue Xie, Hongwei Wang, Bicheng Chen, Hong Zhu

“…Compared with other therapies for diabetic patients, islet transplantation can effectively prevent and reverse diabetes-induced microvascular disease, such as diabetic retinopathy and nephropathy. …”
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Reenvisioning Traditional to Regenerative Therapeutic Advances in Managing Nonalcoholic Fatty Liver Disease in Diabetes Mellitus by Lung-Wen Tsai, Yi-Hsiang Lu, Rajni Dubey, Jeng-Fong Chiou

“…This might be attributable to their differentiation potential towards hepatic and pancreatic lineage. These cellular therapies could be further complemented by platelet-derived biomaterials, TCM formulations, or any specific drug. …”
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The Perspective of Therapeutic Antibody Marketing in Iran: Trend and Estimation by 2025 by Monireh Golpour, Pouya Vatanpour, Mina Amini, Majid Saeedi, Nasim Hafezi, Alireza Rafiei

“…Given the increasing technology of the production of MTAs and their use in targeted therapies worldwide, their consumption market in Iran is expected to grow significantly.…”
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