Showing 18,561 - 18,580 results of 20,793 for search '"Therapy"', query time: 0.28s Refine Results
  1. 18561

    Inhibition of METTL14 overcomes CDK4/6 inhibitor resistance driven by METTL14-m6A-E2F1-axis in ERα-positive breast cancer by Chenlin Liu, Dong Fan, Jiahui Sun, Guodong Li, Ruoxin Du, Xiaoshuang Zuo, Kuo Zhang, Wangqian Zhang, Shuning Wang, Xiaojv Li, Mingrui Du, Donghui Wang, Qiang Hao, Yingqi Zhang, Meng Li, Cun Zhang, Yuan Gao

    Published 2025-01-01
    “…Treatment with folate-conjugated liposomes targeting breast cancer cells that contained both a CDK4/6i and WKYMVM revealed the synergistic effect of METTL14 inhibition with CDK4/6i therapy in a CDK4/6i-resistant PDX model. Together, our findings reveal the mechanism of CDK4/6i resistance and provide a strategy for overcoming CDK4/6i resistance via METTL14 inhibition. …”
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  2. 18562
  3. 18563
  4. 18564

    Effect of feedforward control combined with tracking method on reducing the incidence of blockage of intravenous indwelling needle in perioperative patients (前馈控制追踪法在降低围手术期患者静脉留置针堵... by ZHANG Jianfang (张建芳), SHI Lihua (施丽华), LIN Yiqing (林依青), FENG Qi (冯绮), CHEN Qiyu (陈麒羽), LI Liqin (李立勤)

    Published 2023-03-01
    “…Totally 852 patients who received intravenous infusion therapy were recruited and divided into two groups according to the odd-even number of admission: 424 patients with odd number in the control group and 428 patients with even number in the observation group. …”
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  5. 18565
  6. 18566

    Effect of Shangke Zhitong Ointment Kinesio Tape on Ankle Sprain by WANG Qiang, LIU Zhiyang, JU Shaohua, LI Xiaodong, HUANG Jichao, XIANG Ning

    Published 2023-04-01
    “…In addition, the control group received kinesio tape therapy; the combined group received kinesio tape and Shangke Zhitong ointment; the Shangke kinesio tape group received Shangke Zhitong ointment kinesio tape. …”
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  7. 18567

    Correlation of HER2 expression and clinicopathological characteristics in patients with urothelial carcinoma in China by WANG Shanshan, YE Dingwei, YANG Li, CHENG Fan, YANG Tiejun, ZHANG Xiaoping, YU Zhixian, ZHANG Qingyun, YANG Yong

    Published 2024-11-01
    “…This study underscores the critical importance of accurately assessing HER2 expression in UC patient to guide personalized therapies.…”
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  8. 18568
  9. 18569

    A Randomized Study to Compare the Effects of Once-Weekly Dulaglutide Injection and Once-Daily Glimepiride on Glucose Fluctuation of Type 2 Diabetes Mellitus Patients: A 26-Week Fol... by Huiqin Li, Xiaohua Xu, Jie Wang, Xiaocen Kong, Maoyuan Chen, Ting Jing, Zhiying Zhang, Guoping Yin, Xiaomei Liu, Yun Hu, Lei Ye, Xiaofei Su, Jianhua Ma

    Published 2019-01-01
    “…The Mean Blood Glucose (MBG) of the two groups declined significantly after therapy (P<0.05). However, the Standard Deviation of Blood Glucose (SDBG) decreased significantly only in the dulaglutide group (from 2.57±0.74 mmol/L to 1.98±0.74 mmol/L, P<0.05). …”
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  10. 18570
  11. 18571

    Safety and tolerability of the M2 muscarinic acetylcholine receptor modulator BAY 2413555 in heart failure with reduced ejection fraction in the REMOTE-HF study by Marat Fudim, Muhammad Shahzeb Khan, Dominik Linz, JoAnn Lindenfeld, Calum MacRae, Nina Kimmeskamp-Kirschbaum, Michaela Meyer, Thomas Mondritzki, Hanna Tinel, Wilfried Dinh, Robert J. Mentz

    Published 2024-12-01
    “…Patients were required to have an implanted cardiac defibrillator (ICD) or cardiac resynchronization therapy (CRT) device because of the potential for bradycardia or AV conduction delay, which may be induced by BAY 2413555. …”
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  12. 18572

    Ganoboninketal C from Ganoderma boninense improves the efficacy of CDDP-based chemotherapy through inhibiting translesion DNA synthesis by Xiaolu Ma, Fei Yang, Ke Ma, Hongyan Shen, Junjie Han, Kai Wang, Yeran Yang, Jiawei Zhu, Ruiyuan An, Qilin Wang, Tie-Shan Tang, Bo Zhou, Hongwei Liu, Caixia Guo

    Published 2024-09-01
    “…Interestingly, 26-3 can also sensitize tumor cells to Gefitinib therapy. Mechanistically, through RNA-seq analysis, we found that 26-3 could abrogate the CDDP-induced upregulation of Polη and PIDD (p53-induced protein with a death domain), 2 known factors promoting TLS pathway. …”
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  13. 18573

    Understanding the long‐term impact of the COVID‐19 pandemic on non‐muscle‐invasive bladder cancer outcomes: 12‐Month follow‐up data from the international, prospective COVIDSurg Ca... by Cameron E. Alexander, Arjun Nathan, Alexander Light, Chuanyu Gao, Vinson Chan, Sinan Khadhouri, Kevin Gallagher, Kevin G. Byrnes, Michael Walters, Terry Hughes, Rita Perry, Kelvin Okoth, Laura Magill, Thomas Pinkney, Joseph B. John, John S. McGrath, Alexandra Colquhoun, Yuhao Zhang, James Blackmur, Eric Etchill, Stanley Tang, Damián García Escudero, Grant D. Stewart, Veeru Kasivisvanathan, COVIDSurg Collaborative

    Published 2024-11-01
    “…As a consequence of the COVID‐19 pandemic, 10.9% of patients had site‐declared delay to TURBT/bladder biopsy; 7.4% did not undergo intravesical therapy or had early discontinuation of this; 9.2% did not undergo early repeat resection for high‐risk disease; and 18.3% had a delay to cystoscopic follow‐up surveillance. …”
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  14. 18574

    c-MET-positive circulating tumor cells and cell-free DNA as independent prognostic factors in hormone receptor-positive/HER2-negative metastatic breast cancer by Jieun Park, Eun Sol Chang, Ji-Yeon Kim, Chaithanya Chelakkot, Minjung Sung, Ji-Young Song, Kyungsoo Jung, Ji Hye Lee, Jun Young Choi, Na Young Kim, Hyegyeong Lee, Mi-Ran Kang, Mi Jeong Kwon, Young Kee Shin, Yeon Hee Park, Yoon-La Choi

    Published 2024-01-01
    “…Abstract Background Endocrine therapy resistance in hormone receptor-positive/HER2-negative (HR+/HER2−) breast cancer (BC) is a significant clinical challenge that poses several unmet needs in the management of the disease. …”
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  15. 18575

    Evolution of burnout syndrome in Spanish healthcare professionals during and after the COVID-19 pandemic: psychosocial variables involved by Fernanda Gil-Almagro, Fernanda Gil-Almagro, Fernanda Gil-Almagro, F. Javier Carmona-Monge, Fernando J. García-Hedrera, Cecilia Peñacoba-Puente

    Published 2025-02-01
    “…., optimism and hopelessness), therapies more focused on the meaning of existence, such as Acceptance and Commitment Therapy, could be useful.…”
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  16. 18576

    Safety and efficacy of catheter ablation in atrial fibrillation patients with heart failure with preserved ejection fraction by Songbing Long, Yuanjun Sun, ShiYu Dai, Xianjie Xiao, Zhongzhen Wang, Wei Sun, Lianjun Gao, Yunlong Xia, Xiaomeng Yin

    Published 2025-01-01
    “…Methods Three groups of AF patients were included in the study: 187 patients with HFPEF for their first CA (AFPHF-CA), 187 patients with HFPEF who were undergoing medical therapy (AFPHF-Med), and 196 patients without HFPEF for their first CA (AF-CA). …”
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  17. 18577

    Radiotherapy(R) Integration(I) Strategy for Small(S)-Cell Lung Cancer in Extensive(E) Stage (RISE) with up to 10 metastases- a study protocol of a randomized phase II trial by Łukasz Kuncman, Jacek Fijuth, Damian Tworek, Ewa Sierko, Paweł Cisek, Michał Masłowski, Maja Lisik-Habib, Magdalena Orzechowska, Katarzyna Galwas-Kliber, Adam Antczak, Izabela Chmielewska, Barbara Ziółkowska, Marta Kurczewska-Michalak, Wojciech Kuźnicki, Nina Jędrzejczak, Kinga Ranoszek, Mateusz Bilski

    Published 2025-01-01
    “…There is a lack of data on incorporating RT as chest consolidation and metastasis-directed therapy for ED-SCLC. The RISE (Radiotherapy for Extensive-Stage Small-Cell Lung Cancer) study aims to evaluate the effectiveness of different RT strategies for residual lesions for patients with ED-SCLC who receive chemo-immunotherapy. …”
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  18. 18578

    Non-thermal atmospheric pressure plasma-irradiated cysteine protects cardiac ischemia/reperfusion injury by preserving supersulfides by Akiyuki Nishimura, Tomohiro Tanaka, Kakeru Shimoda, Tomoaki Ida, Shota Sasaki, Keitaro Umezawa, Hiromi Imamura, Yasuteru Urano, Fumito Ichinose, Toshiro Kaneko, Takaaki Akaike, Motohiro Nishida

    Published 2025-02-01
    “…Non-thermal atmospheric pressure plasma irradiation therapy is attracted attention as it exerts beneficial effects by producing various reactive molecular species. …”
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  19. 18579

    Effect of salmon calcitonin on bone mineral density of patients with osteoporotic vertebral compression fractures (鲑降钙素对骨质疏松椎体压缩性骨折患者骨密度的影响)... by CAO Min (曹敏), CHEN Siling (陈思伶), LI Na (李娜), JI Tian (纪甜), YANG Yan (杨燕), YANG Liyun (杨丽云), JIAN Huiqing (蹇会清)

    Published 2023-05-01
    “…The control group received routine antiosteoporosis therapy(Teriparatide and Chinese medicine capsules for osteoporosis), and the study group was given salmon calcitonin combined with Chinese medicine capsules for osteoporosis. …”
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  20. 18580

    Insufficient Evidence to Recommend Shu Mian Capsule in Managing Depression With or Without Comorbid Insomnia: A Systematic Review With Meta-Analysis and Trial Sequential Analysis by Zhao FY, Xu P, Kennedy GA, Jin X, Wang YM, Zhang WJ, Yue LP, Ho YS, Fu QQ, Conduit R

    Published 2025-01-01
    “…Further rigorous trials are warranted to confirm SMC’s short-term efficacy and explore its medium- to long-term effects as either an alternative or complementary therapy. Current evidence precludes recommendations for the administration of SMC in depression.Keywords: Chinese patent medicine, commercial Chinese polyherbal preparation, Chinese medicine, herbal medicine, depressive disorder, major depressive disorder, sleep quality…”
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