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18041
Course of COVID-19 in Patients with Inflammatory Bowel Disease: Regional Experience
Published 2023-02-01“…In our cohort, there were fewer patients receiving biological therapy, but more patients on 5-aminosalicylic acid (5-ASA) and systemic corticosteroids. …”
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18042
Medical treatment for dry eye in patients with keratoconus after corneal cross-linking
Published 2020-06-01“…Postoperative tear substitutes and reparative therapy result in the significant improvement of tear film stability.…”
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18043
Forty years of HIV infection and AIDS in Taiwan: Reflection on the past and looking toward the future
Published 2025-02-01“…With the introduction of combination antiretroviral therapy (ART) in Taiwan in 1997, the incidences of HIV-related opportunistic illnesses and mortality have significantly declined. …”
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18044
Protection of Fecal Microbiota Transplantation in a Mouse Model of Multiple Sclerosis
Published 2020-01-01“…Taken together, our data suggest that FMT, as a GM-based therapy, has the potential to be an effective treatment for MS.…”
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18045
Assessing the validity and reliability of the Indonesian version of Patient-Reported Outcomes Measurement Information System (PROMIS) Global Health Scale v1.2
Published 2025-01-01“…PROMIS Global Health Scale v1.2 was subjected to translation and cultural adaptation using the Functional Assessment of Chronic Illness Therapy (FACIT) method. Content validity was tested by five experts using the Scale-Content Validity Index (S-CVI), and structural validity was evaluated through Confirmatory Factor Analysis (CFA). …”
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18046
Geriatric nutritional risk index as a predictor of 30-day and 365-day mortality in patients with acute myocardial infarction: a retrospective cohort study using the MIMIC-IV databa...
Published 2025-02-01“…A landmark analysis at 20 days after admission further demonstrated the impact of GNRI on mortality during different phases of recovery.ConclusionThis study highlights the prognostic value of GNRI in predicting short-term and long-term mortality in AMI patients, emphasizing the significance of nutritional status and inflammatory indicators in the therapy and risk assessment of these individuals.…”
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18047
Analysis of mRNA Pentatricopeptide Repeat Domain 1 as a prospective oncogene in clear cell renal cell carcinoma that accelerates tumor cells proliferation and invasion via the Akt/...
Published 2025-01-01“…Our findings indicated that PTCD1 had the potential to become a new target for predicting prognosis and targeted therapy.…”
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18048
Factors affecting quality of life in women post mastectomy for breast cancer in Baheya Foundation (Egypt): ‘A retrospective cohort study’
Published 2025-02-01“…In contrast, women who received hormonal therapy had higher role functioning (17.64, p < 0.010), with less complaints of diarrhoea (-10.38, p < 0.010), nausea (-8.668, p < 0.010) and pain (-8.265, p < 0.050). …”
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18049
Assessment of Effect of Magnesium Intake on Blood Pressure Control in Hypertensives: A Case-control Study with a Nested Intervention of Flax Seeds Administration to Increase Magnes...
Published 2024-08-01“…Flaxseeds can be used in hypertensive patients as an adjuvant to drug therapy to improve BP control. Clinical significance: Hypertensive patients can be advised to consume flax seeds regularly to maintain healthy magnesium levels and control hypertension.…”
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18050
Transarterial Chemoembolization Plus Radiofrequency Ablation and Iodine-125 Seed Implantation for Hepatocellular Carcinoma in High-Risk Locations: A Propensity Score-Matched Analys...
Published 2025-01-01“…The aim of this study was to compare the clinical outcomes of TACE-RFA plus iodine-125 (125I) seed implantation (TACE-RFA-125I) therapy with those of TACE-RFA for unresectable HCC (≤ 5 cm) in high-risk locations.Methods: From January 2010 to June 2023, the clinical data of 126 patients with unresectable HCC (≤ 5 cm) in high-risk locations who received TACE-RFA-125I or TACE-RFA treatment were retrospectively analyzed. …”
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18051
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18052
Interferon gamma‐mediated prevention of tumor progression in a mouse model of multiple myeloma
Published 2024-12-01“…Abstract Malignant plasma cells in multiple myeloma patients reside in the bone marrow and continuously interact with local immune cells. Progression and therapy response are influenced by this immune environment, highlighting the need for a detailed understanding of endogenous immune responses to malignant plasma cells. …”
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18053
Pharmacological Vitamin C-induced high H2O2 generation mediates apoptotic cell death by caspase 3/7 activation in breast cancer tumor spheroids
Published 2025-01-01“…Unlike traditional in vitro studies, this work provides novel insights into the response of two BC tumor subtypes to Vit-C, demonstrating its potential as a targeted common therapy for BC.…”
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18054
Impact of Timing the Combination of Radiotherapy and PD-1 Inhibitors on Outcomes in Patients with Hepatocellular Carcinoma
Published 2025-01-01“…This study aimed to evaluate and compare the efficacy and treatment-related adverse events (TRAEs) of synchronously administered radiotherapy and programmed cell death protein (PD)-1 inhibitors and sequential administration in patients with HCC.Patients and Methods: We retrospectively enrolled 67 patients with HCC who were undergoing liver radiotherapy and PD-1 inhibitor therapy at two medical centers between July 2017 and April 2023. …”
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18055
Simultaneous Quantification of Pioglitazone and Omarigliptin in Rat Plasma by UHPLC-MS/MS and Its Application to Pharmacokinetic Study after Coadministration of the Two Drugs
Published 2021-01-01“…Combination therapy is a common approach for clinical treatment of type 2 diabetes mellitus, especially for patients with poor monotherapy. …”
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18056
Inhibitory potential of probiotic spore formers grown as mono- and mix-cultures under conditions of different nutrient availability
Published 2024-12-01“…In many clinical cases, the use of probiotic microorganisms is a safer alternative to antibiotic therapy. Spore-forming probiotics, due to their high resistance to damaging environmental factors, stand out among other beneficial microorganisms and, therefore, deserve special attention. …”
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18057
Evaluating the quality of care for heart failure hospitalizations in inflammatory arthritis – A population-based cohort study
Published 2025-03-01“…Guideline-directed medical therapy (GDMT) adherence was evaluated within 90 days and classified as perfect, moderate, or poor. …”
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18058
The combination of kidney function variables with cell cycle arrest biomarkers identifies distinct subphenotypes of sepsis-associated acute kidney injury: a post-hoc analysis (the...
Published 2024-12-01“…We then compared the subphenotypes with regard to a composite outcome of in-hospital death or the initiation of renal replacement therapy (RRT).Results We included 184 patients presenting SA-AKI within 6 h of the initiation of catecholamines. …”
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18059
Surgical Resection with Neoadjuvant Chemotherapy for Locoregionally Recurrent Appendiceal Cancer Invading the External Iliac Vessels
Published 2018-01-01“…Recent advancements in multimodal therapy can provide oncologic benefits for patients with recurrent colorectal cancer. …”
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18060