Yoruba Epistemology, Art, Language and the Universe of Meanings: A Meta-Analysis by Michael O. Afolayan

“…It is a needed shock therapy, an organic rendition of an intellectual exposition of the Yoruba art. …”
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Establishing a Surgical Procedure for Rhesus Epiretinal Scaffold Implantation with HiPSC-Derived Retinal Progenitors by Ziming Luo, Kang Li, Kaijing Li, Bikun Xian, Ying Liu, Sijing Yang, Chaochao Xu, Zhigang Fan, Shoutao Lu, Haijun Zhang, Jian Ge

“…The established surgical procedure offers a new insight into research of epiretinal cell replacement therapy in rhesus eyes. The successful delivery and long-term fixation provide a prerequisite for cell migration and integration.…”
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Multi-omics mechanical analysis of gut microbiota, carboxylic acids, and cardiac gene expression interaction triggering diabetic cardiomyopathy by Meixin Shi, Bingbing Zhao, Wenjie Cai, Hui Yuan, Xiao Liang, Zhitao Li, Xinyu Liu, Ye Jin, Xi Liu, Can Wei

“…This study provides a theoretical basis for investigating the mechanism of DCM and may provide preliminary evidence for the future use of gut microbiota therapy for DCM.…”
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Effect of Respiratory Training combined with Core Stability Training for Children with Spastic Cerebral Palsy by Binong HU, Kai ZHANG, Fang QI, Chunhua WANG, Wenyin ZHOU, Kun AI, Hong ZHANG

“…Objective:To observe the effect of respiratory training combined with core stability training on motor function, balance function and daily life ability of children with spastic cerebral palsy.Methods:A total of 74 children with spastic cerebral palsy who were treated in the deparment of child rehabilitation of Xiangya fraternity rehabilitation hospital from March to December 2019, which were divided into the control group and the observation group according to the random number table, with 37 cases in each group.In the course of treatment, two cases dropped in each group, and finally 35 cases were included in each group.The control group was given core stability training on the basis of routine rehabilitation training.The routine rehabilitation training mainly included stretching training, joint range of motion training and occupational therapy, 10 minutes each time.Core stability training mainly included bypass training, sitting up training, suspension system training and Bobath ball training, 40 minutes per time.On the basis of routine rehabilitation training in the control group, the core stability training time of the observation group reduced from 40 minutes to 20 minutes each time, and then received respiratory training, 20 minutes each time.Respiratory training mainly includes abdominal respiratory training(7 min per time), chest expanding exercise training(3 min per time), respiratory aid method training(4 min per time), and anti blocking respiratory training(6 min per time).All the above items were trained twice a day, five times a week, continuous treatment for three months.Before and after treatment for three months, D and E functional domains of gross motor function measure scale-88(GMFM-88)was used to assess the gross motor function such as standing, walking, running and jumping; the Berg balance scale(BBS)was used to assess the balance function;and the Barthel index(BI)was used to assess the daily life activity ability.Results:Before treatment, there were no significant difference in the D and E functional domains scores of GMFM-88, BBS scores and BI scores between the two groups, with no statistically significant differences(<italic>P</italic>&gt;0.05).Compared with before treatment, the D and E functional domains of scores GMFM-88, BBS scores, BI scores of the both groups after treatment for three months were significantly improved, with statistically significant differences(<italic>P</italic>&lt;0.05).Compared with the control group, the D and E functional domains of scoresGMFM-88, BBS scores, BI scores in the observation group were significantly higher than those of the control group, with statistically significant differences(<italic>P</italic>&lt;0.05).Conclusion:Respiratory training combined with core stability training can significantly improve the gross motor function, balance function and daily life ability of children with spastic cerebral palsy, which is worthy of clinical promotion.…”
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The Role of Platelet-Rich Plasma (PRP) in Enhancing IVF Success in Women With Ovarian Insufficiency: A Cohort Study by Zahra Mohammad Alipour, Farahnazsadat Ahmadi, Sina Mohajernoei, Roghaye Gharaei, Nazanin Hojjati, Elham Shirali, Firouzeh Akbari Asbagh

“…The findings suggest that with longer follow-up and larger sample sizes, PRP could be validated as a promising adjunctive therapy for women with ovarian insufficiency undergoing IVF. …”
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Efficacy and safety of FOLFIRI/aflibercept in second‐line treatment of metastatic colorectal cancer in a real‐world population: Prognostic and predictive markers by Ana Fernández Montes, Nieves Martínez Lago, Marta Covela Rúa, Juan de la Cámara Gómez, Paula González Villaroel, José Carlos Méndez Méndez, Mónica Jorge Fernández, Mercedes Salgado Fernández, Margarita Reboredo López, Guillermo Quintero Aldana, María Luz Pellón Augusto, Begoña Graña Suárez, Jesús García Gómez

“…Results Patients had good general status (PS 0‐1 96.2%), tumours were mostly RAS‐mutant (75.6%), synchronous (71.8%), and left‐sided (71.8%). Prior therapy included bevacizumab (47.4%) and anti‐EGFR agents (12.8%). …”
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Utilization of cardiopulmonary bypass at radical nephrectomy for renal cell carcinoma with tumour thrombus by Chalairat Suk‐Ouichai, Mitchell M. Huang, Clayton Neill, Christopher K. Mehta, Ashley E. Ross, Shilajit D. Kundu, Kent T. Perry Jr, Duc T. Pham, Hiten D. Patel

“…Eleven patients (15.3%) had undergone neoadjuvant therapy, and 81% had clear‐cell RCC. CPB was utilized in eight (11.1%) cases. …”
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Nomograms Predicting Survival, Recurrence and Beneficiary Identification of Adjuvant Chemotherapy in Treatment-naïve Patients with Rectal Cancer who Underwent Upfront Curative Rese... by Yukihide Kanemitsu, MD, Tomofumi Uotani, MD, Shunsuke Tsukamoto, PhD, Hideki Ueno, PhD, Megumi Ishiguro, PhD, Soichiro Ishihara, PhD, Koji Komori, PhD, Kenichi Sugihara, PhD, Study Group for Nomogram of the Japanese Society for Cancer of the Colon and Rectum

“…Although multidisciplinary treatment is standard for locally advanced RC, understanding surgical efficacy is important for determining indications for perioperative adjuvant therapy. Methods:. RC patients who underwent upfront surgery at the Japanese Society for Cancer of the Colon and Rectum institutions were analyzed. …”
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Ketamine effects on resting state functional brain connectivity in major depressive disorder patients: a hypothesis-driven analysis based on a network model of depression by Kasper Recourt, Joop Van Gerven, Joop Van Gerven, Nadieh Drenth, Jeroen van der Grond, Kantaro Nishigori, Nic J. Van Der Wee, Gabriël E. Jacobs, Gabriël E. Jacobs

“…Ketamine’s antidepressant effects and its impact on functional networks in non-resistant forms of major depressive disorder are expected to provide valuable insight into ketamine’s mechanism of action related to depression.MethodsThis study employs an existing network model of major depressive disorder to investigate the effects of ketamine on resting state connectivity in a therapy-non-resistant major depressive disorder population. …”
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Momordica Charantia Polysaccharides Attenuates MPP+-Induced Injury in Parkinson’s Disease Mice and Cell Models by Regulating TLR4/MyD88/NF-κB Pathway by Dengjun Guo, Jie Zhou, Meng Zhang, Reyisha Taximaimaiti, Xiaoping Wang, Hai Wang

“…This study found that the application of MCPs therapy can play anti-inflammatory, antioxidative stress, and antiapoptotic effects in PD by regulating the activation of the TLR4/MyD88/NF-κB pathway.…”
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Socio-Demographic and Lifestyle Factors Influencing Adherence to AntiHypertensive Treatment in a Rural Area of Ludhiana, India by Sangeeta Girdhar, ,Mahesh Satija, Daljit Kaur, .Anurag Chaudhary

“…Non-adherence to drug therapy among anti-hypertensives is a matter worth concern. …”
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Assessment of the quality of life in metastatic colorectal cancer patients with KRAS gene mutant: a case-control study by Fahmideh Bagrezaei, Bahram Pourghassem Gargari, Reza Eghdam Zamiri, Abdolrasoul Safaiyan, Mohammad Alizadeh

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Lysozyme-based spray for treatment of radiotherapy-induced oral mucositis by Zdenka Gojković, Jelena Rožić, Nataša Gašpar, Aziz Šukalo, Meliha Mehić, Amna Tanović Avdić, Una Glamočlija

“…The efficacy and safety of therapy were evaluated on the baseline and three follow-up visits (7, 14, and 21 days after the baseline visit). …”
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A scoping review on the obstacles faced by beta thalassemia major patients in Pakistan- Matter of policy investment by Ali Hussain Ansari, Saqib Hussain Ansari, Mubarak Jabeen Salman, Muhammad Usman Hussain Ansari, Rawshan Jabeen

“…To address these issues, essential recommendations include the following: the implementation of a standardized protocol for β-TM care, the enhancement of access to quality care, the provision of iron chelation therapy, and safeguarding safe blood transfusion practices. …”
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Celecoxib Improves Host Defense through Prostaglandin Inhibition during Histoplasma capsulatum Infection by Priscilla Aparecida Tartari Pereira, Bruno Caetano Trindade, Adriana Secatto, Roberto Nicolete, Camila Peres-Buzalaf, Simone Gusmão Ramos, Ruxana Sadikot, Claudia da Silva Bitencourt, Lúcia Helena Faccioli

“…Thus, the inhibition of prostaglandins could be a valuable immunomodulatory strategy and antifungal therapy for histoplasmosis treatment.…”
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Human Fat-Derived Mesenchymal Stem Cells Xenogenically Implanted in a Rat Model Show Enhanced New Bone Formation in Maxillary Alveolar Tooth Defects by Andrew Wofford, Austin Bow, Steven Newby, Seth Brooks, Rachel Rodriguez, Tom Masi, Stacy Stephenson, Jack Gotcher, David E. Anderson, Josh Campbell, Madhu Dhar

“…Due to restorative concerns, bone regenerative therapies have garnered much attention in the field of human oral/maxillofacial surgery. …”
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Diagnostic Management and Surgical Treatment of Isolated Tricuspid Regurgitation by Arthur Cicupira Rodrigues de Assis, Gustavo Andre Boeing Boros, Lea Maria Macruz Ferreira Demarchi, Thiago Luis Scudeler, Paulo Cury Rezende

“…Because of persistent symptoms, even after optimization of medical therapy, the patient was submitted to tricuspid valve replacement surgery. …”
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Drug-Drug Interactions Between HIV Antivirals and Concomitant Drugs in HIV Patients: What We Know and What We Need to Know by Emanuela De Bellis, Danilo Donnarumma, Adele Zarrella, Salvatore Maria Mazzeo, Annarita Pagano, Valentina Manzo, Ines Mazza, Francesco Sabbatino, Graziamaria Corbi, Pasquale Pagliano, Amelia Filippelli, Valeria Conti

“…Highly active antiretroviral therapy has led to a significant increase in the life expectancy of people living with HIV. …”
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HGF-Modified Dental Pulp Stem Cells Mitigate the Inflammatory and Fibrotic Responses in Paraquat-Induced Acute Respiratory Distress Syndrome by Panpan Geng, Yuning Zhang, Huan Zhang, Xiwen Dong, Yuefeng Yang, XiaoNa Zhu, Chu-Tse Wu, Hua Wang

“…Paraquat (PQ) poisoning can cause acute lung injury and progress to pulmonary fibrosis and eventually death without effective therapy. Mesenchymal stem cells (MSCs) and hepatocyte growth factor (HGF) have been shown to partially reverse this damage. …”
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Identification of SETD4 as an Onco‐Immunological Biomarker Encompassing the Tumor Microenvironment, Prognoses, and Therapeutic Responses in Various Human Cancers by Yuyun Zhong, Ruiqi Wang, Zijie Huang, Zhaoting Hu, Bin Peng, Bin Chen, Liyue Sun

“…Conclusions This study demonstrates that SETD4 is an immune‐oncogenic molecule in multiple cancers, with the potential to be a diagnosis, prognosis, and targeted therapy marker.…”
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