Satisfied with the worst health outcomes or unsatisfied with the best: explaining the divergence between good patient-reported outcomes and low satisfaction and vice versa among kn... by Lukas Schöner, Viktoria Steinbeck, Reinhard Busse, Carlos J. Marques

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Prognosis of Elderly Japanese Patients Aged ≥80 Years Undergoing Hemodialysis by Shingo Hatakeyama, Hiromi Murasawa, Itsuto Hamano, Ayumu Kusaka, Takuma Narita, Masaaki Oikawa, Daisuke Noro, Kazuhisa Hagiwara, Hirofumi Ishimura, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Hisao Saitoh, Tomihisa Funyu, Chikara Ohyama

“…From January 1988 to July 2013, 1144 consecutive patients with end-stage renal disease required renal replacement therapy at our institution; of these, 141 were aged ≥80 years. …”
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Association of sexual performance and intimacy with satisfaction in life in head and neck cancer patients: A review by Ananya Arora, Ravindra Singh, Khushi Malik, Unnati Kestwal

“…Introduction: Head and neck (H&N) neoplasms, both in advanced stages and during their oncologic therapy, cause interferences with wild psycho-physical implications and impact on family and partner life, social, relational, and working dimensions. …”
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Argonaute2 and Argonaute4 Involved in the Pathogenesis of Kawasaki Disease via mRNA Expression Profiles by Zon-Min Lee, Hui-Chuan Chang, Shih-Feng Liu, Ying-Hsien Huang, Ho-Chang Kuo

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The effect of L-carnitine supplementation on anthropometric and malnutrition status in acute ischemic stroke patients: a triple-blinded randomized clinical trial by Samaneh Hajjarzadeh, Mehdi Zarei, Shahram Rafie, Davood Shalilahmadi, Majid Karandish

“…Conclusions Early L-carnitine supplementation effectively improves anthropometric indices and malnutrition, muscle wasting, and rapid weight loss in acute ischemic stroke patients, highlighting its potential as a supportive nutritional therapy during stroke rehabilitation. Trial registration The current clinical trial study was registered in the Iranian Registry of Clinical Trials (registration code: IRCT20221206056734N1) at 2023-02-11.…”
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Advancements in Regenerative Medicine for Articular Cartilage Repair in the Management of Osteoarthritis: A Review of Modern Treatment Methods by Jakub Dziewic, Maria Przygoda, Joanna Śnieżna, Gabriela Trestka, Kamila Stępień, Sabina Adamczyk, Urszula Zelik, Wojciech Florczak, Wiktoria Domino, Jagienka Włodyka, Karol Dzwonnik

“…In this review, modern regenerative methods used in the repair of articular cartilage, both traditional techniques and innovative cellular therapies, are described. It focuses on the most updated treatment modalities, discussing, among other methods, microfracture, osteochondral grafts, autologous chondrocyte implantation (ACI), novel approaches of matrix-assisted autologous chondrocyte transplantation (MACT) and mesenchymal stem cell (MSC) treatments, with especial regard toward the use of platelet-rich plasma (PRP) in relation to other intra-articular injections, namely hyaluronic acid and ozone therapy. …”
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Effects of low, moderate, and high-intensity aquatic exercise on joint edema in induced rat knee arthritis by Alline Mardegan Mioto, Daniel Fernando dos Reis, Thiago Alves Garcia, Guilherme Akio Tamura Ozaki, Iara Buriola Trevisan, Rodrigo Metzker Pereira Ribeiro, Robson Chacon Castoldi, José Carlos Silva Camargo Filho

“… Introduction: Arthritis has prompted interest in using physical exercise as therapy. This study assesses the effects of low-, moderate-, and high-intensity exercise on induced arthritis in male Wistar rats. …”
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Contribution of Short-Time Occlusion of the Amblyopic Eye to a Passive Dichoptic Video Treatment for Amblyopia beyond the Critical Period by Lauren Sauvan, Natacha Stolowy, Danièle Denis, Frédéric Matonti, Frédéric Chavane, Robert F. Hess, Alexandre Reynaud

“…The passive movie approach combined with interocular contrast balancing even over such a short period as 2 weeks has potential as a clinical therapy to treat amblyopia in older children and adults.…”
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A Nomogram Built on Clinical Factors and CT Attenuation Scores for Predicting Treatment Response of Acute Myeloid Leukemia Patients by Linna Liu, Wenzheng Lu, Li Xiong, Han Qi, Robert Peter Gale, Bin Yin

“…This study aims to develop a nomogram combining clinical and CT-based factors to predict treatment response and guide personalized therapy for AML patients. <b>Methods</b>: This retrospective study included 74 newly diagnosed AML patients who underwent unenhanced abdominal CT scans within one week before receiving their first induction chemotherapy. …”
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Analysis of parameters of purine metabolism in patients with diabetes mellitus type 2 by A.O. Chernyaeva, M.R. Mykytyuk, Yu.I. Karachentsev

“…All subjects received oral hypoglycemic therapy. The researchers determined anthropometric indicators, indicators of carbohydrate metabolism, concentration of creatinine, uric acid, parameters of the blood lipid spectrum, purine bases, activity of xanthine oxidase and hypoxanthine-guanine-phosphoribosyltransferase in the blood. …”
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Achilles Tendon Rupture In Recreational Athletes - Hobby-Ending Incident or Easily Treatable Injury? Current Insight Into Risk Factors, Treatment Options and Recovery Strategies by Jakub Kędzia, Joanna Duda, Kinga Racisz, Paweł Racisz, Alicja Obcowska, Aleksandra Walendzik, Łukasz Sencerek

“…Conclusion: Optimal outcomes for ATR treatment are achieved through operative intervention, particularly minimally invasive surgery, paired with early rehabilitation. Physical therapy, blood-flow restriction training, and stretching can aid return to sport. …”
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A Mitochondria‐Related Signature in Diffuse Large B‐Cell Lymphoma: Prognosis, Immune and Therapeutic Features by Zhen‐Zhong Zhou, Jia‐Chen Lu, Song‐Bin Guo, Xiao‐Peng Tian, Hai‐Long Li, Hui Zhou, Wei‐Juan Huang

“…Gene pathway level, microenvironment, expression of targeted therapy‐associated genes, response to immunotherapy, drug sensitivity, and somatic mutation status were compared between clusters. …”
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A national study of clinical discussions about cannabis use among Veteran patients prescribed opioids by Tauheed Zaman, Dawn M. Bravata, Amy Byers, Erin Krebs, Samuel Leonard, Charles Austin, Friedhelm Sandbrink, Deborah S. Hasin, Salomeh Keyhani

“…Abstract Background The Veterans Health Administration tracks urine drug tests (UDTs) among patients on long-term opioid therapy (LTOT) and recommends discussing the health effects of cannabis use. …”
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Square-Stepping HIIT Combined With 'Phyllanthus amarus' Supplementation Alleviates Fasting Blood Glucose and Oxidative Stress in Overweight and Obese Individuals by Surachat Buddhisa, Nattaphol Prakobkaew, Piyapong Prasertsri, Sudarat Boonpitak, Puttipong Poncumhak, Orachorn Boonla

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Treatment of Proximal Humeral Fractures in Older Patients During COVID-19 Pandemic in Germany by Sußiek J, Koeppe J, Fischhuber K, Iking J, Marschall U, Raschke MJ, Katthagen JC, Stolberg-Stolberg J

“…During the lockdown periods, the total incidence fell, while the outpatient incidence partially increased during the pandemic-period. Regarding the therapy allocation, there were no relevant persisting changes. …”
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Investigation of calonysterone and 20-hydroxyecdysone effects in high-fat, high-sugar diet-induced obesity rat model by Alaa AM. Osman, Dávid Laczkó, Máté Vágvölgyi, Adrienn Seres-Bokor, Anita Sztojkov-Ivanov, Kata Kira Kemény, Attila Hunyadi, Eszter Ducza

“…Overweight constitutes a significant health and social issue in developed nations globally. Conventional therapies such as lifestyle modification (nutrition and physical activity) have limited weight reduction. …”
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Prognostic Factors on the Graft-versus-Host Disease-Free and Relapse-Free Survival after Adult Allogeneic Hematopoietic Stem Cell Transplantation by Yao-Chung Liu, Sheng-Hsuan Chien, Nai-Wen Fan, Ming-Hung Hu, Jyh-Pyng Gau, Chia-Jen Liu, Yuan-Bin Yu, Liang-Tsai Hsiao, Tzeon-Jye Chiou, Cheng-Hwai Tzeng, Po-Min Chen, Jin-Hwang Liu

“…A novel composite endpoint of GVHD-free/relapse-free survival (GRFS) in which events include grades 3-4 acute GVHD, chronic GVHD requiring systemic therapy, relapse, or death is censored to completely characterize the survival without mortality or ongoing morbidity. …”
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Cross-cultural adaptation and validation of a Norwegian version of the Goodman Satisfaction Score (GSS-NO) for patients with total hip and knee arthroplasty by Ingvild Buset Bergvad, Anders Kottorp, Arild Aamodt, Anners Lerdal, Søren T Skou, Maren Falch Lindberg

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Therapeutic target genes and regulatory networks of gallic acid in cervical cancer by Zhixi You, Ye Lei, Yongkang Yang, Zhihui Zhou, Xu Chao, Keyi Ju, Songyi Wang, Yuanyuan Li, Yuanyuan Li

“…The upstream 13 miRNAs, 4 lncRNA, and 42 circRNAs were detected and used to construct a lncRNA/circRNA-miRNA-mRNA-pathway regulatory network.ConclusionThis study identified candidate genes and the regulatory networks underlying the therapeutic effects of GA on CC using GA data mining methods, thus establishing a theoretical basis for targeted therapy of CC.…”
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The effect of bacterial overgrowth syndrome and bacterial translocation on the course of liver cirrhosis by M. S. Zharkova, M. V. Mayevskaya, V. T. Ivashkin

“…Ascitis, resistant to diuretic therapy was more frequent in patients with bacterial translocation (66,7%) in comparison to patients without it (14,3%) [OR 4,667; 95%CI: 0,717–30,353; р=0,036]. …”
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