Anxiety, depression, and insomnia among medical and non-medical students in Jordan: a cross-sectional study by Jehad Feras AlSamhori, Diala Ra’Ed Kamal Kakish, Abdel Rahman Feras AlSamhori, Ahmad Feras AlSamhori, Noor Rajeh Abu Hantash, Afnan Firas Abu Swelem, Mamoun Hamed Ali Abu-Suaileek, Hazar Mohammed Arabiat, Mohammad Anwer Altwaiqat, Radwan Banimustafa, Abdallah Barjas Qaswal, Abdulqadir J. Nashwan

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In Vivo Evaluation of the Ameliorating Effects of Small-Volume Resuscitation with Four Different Fluids on Endotoxemia-Induced Kidney Injury by Yan-ling Wang, Jing-hui Chen, Qiong-fang Zhu, Gao-feng Yu, Chen-fang Luo, Gang-jian Luo, Shang-rong Li, Zi-qing Hei

“…Fluid resuscitation is the main therapy. However, heart failure is usually lethal for those patients receiving large volumes of fluids. …”
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EGFR-Mutated Lung Adenocarcinoma With Li–Fraumeni Syndrome: The Imperative for Germline Testing in Patients With a Family History, a Case Report by Hiroyuki Fujii, MD, Yusuke Okuma, MD, PhD, Makoto Hirata, MD, PhD, Yuki Shinno, MD, PhD, Tatsuya Yoshida, MD, PhD, Yasushi Goto, MD, PhD, Hidehito Horinouchi, MD, PhD, Noboru Yamamoto, MD, PhD, Yuichiro Ohe, MD, PhD

“…However, CGP provides opportunities for molecular-targeted therapy, but it also unveils incidental germline findings, posing challenges and opportunities in patient care.We present the case of a 32-year-old female patient, diagnosed with stage IVB lung adenocarcinoma harboring an EGFR p.L746_A750del, who was also subsequently diagnosed with Li–Fraumeni syndrome (LFS) through CGP testing. …”
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Association between phase angle and daily creatinine excretion changes in critically ill patients: an approach to muscle mass by Patricio Vargas-Errázuriz, Patricio Vargas-Errázuriz, Natalia Dreyse, Natalia Dreyse, Natalia Dreyse, René López, René López, Marcelo Cano-Cappellacci, Jerónimo Graf, Julia Guerrero, Julia Guerrero

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Management of volume load for patients undergoing hemodialysis via WeChat and home monitoring in China: a protocol for a cluster-randomized trial by Xiaocui Wang, Bonan Yan, Shipeng Zhang, Yuanke Zhou, Qinxiu Zhang, Xueying Li

“…Abstract Background Volume overload is a major mortality risk in hemodialysis (HD) patients. Drug therapy and conventional dialysis limitations underscore the importance of managing volume load through effective lifestyle interventions. …”
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Sex Disparity in Characteristics, Management, and In-Hospital Outcomes of Patients with ST-Segment Elevated Myocardial Infarction: Insights from Henan STEMI Registry by Shan Wang, You Zhang, Qianqian Cheng, Datun Qi, Xianpei Wang, Zhongyu Zhu, Muwei Li, Junhui Zhang, Dayi Hu, Chuanyu Gao, On behalf of Henan STEMI registry study group

“…Eligible women were less likely to receive reperfusion therapy (56.1% vs. 62.4%, P<0.001); the onset to first medical contact (FMC) (255 vs. 190 minutes, P<0.001), onset to fibrinolysis (218 vs. 185 minutes, P<0.001), and onset to percutaneous coronary intervention (PCI) (307 vs. 243 minutes, P<0.001) were significantly delayed in women. …”
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Integrated traditional Chinese and western medicine nursing of a patient undergoing toe amputation for diabetic foot ulcers (1例糖尿病足截趾术后患者的中西医结合护理体会)... by TONG Fenfei (仝粉飞), ZHI Hui (智慧), LIU Jinjing (刘津京), ZHENG Wen (郑雯)

“…Based on the Traditional Chinese Medicine syndrome differentiation, Traditional Chinese Medicine ointment rubbing, Tuina on meridian and acupoints, five-element music therapy were carried out to relieve pain, eliminate lower limb swelling, promote wound healing, reduce the incidence of local infection and complications, improve peripheral circulation and neurotrophic status, improve patients' self-care ability and quality of life. . …”
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Rational strategies for designing next-generation oncolytic viruses based on transcriptome analysis of tumor cells infected with oncolytic herpes simplex virus-1 by Naeme Javid, Shahriyar Abdoli, Majid Shahbazi, Majid Shahbazi

“…IntroductionOncolytic herpes simplex viruses (oHSVs) are a type of biotherapeutic utilized in cancer therapy due to their ability to selectively infect and destroy tumor cells without harming healthy cells. …”
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Ketogenic diet treatment for super-refractory status epilepticus in the intensive care unit: feasibility, safety and effectiveness by Yishu Ren, Mengyao Zhang, Xinxiao Fu, Yan Zhang, Fang Liu, Chenglin Wu, Haiyan Shi, Fei Tian, Gang Liu, Yicong Lin, Yingying Su, Weibi Chen

“…No patient died due to KD, and neurofunctions continued to improve under KD therapy.ConclusionThe KD may be feasible and effective for the treatment of SRSE in the ICU. …”
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Nootkatone Derivative Nootkatone-(E)-2-iodobenzoyl hydrazone Promotes Megakaryocytic Differentiation in Erythroleukemia by Targeting JAK2 and Enhancing JAK2/STAT3 and PKCδ/MAPK Cro... by Yang Pan, Feng Xiao, Chaolan Pan, Hui Song, Peng Zhao, Meijun Chen, Liejun Huang, Jue Yang, Xiaojiang Hao

“…In conclusion, N2 shows great promise as a differentiation therapy for erythroleukemia, offering a novel approach by targeting JAK2-mediated signaling pathways to induce megakaryocytic differentiation.…”
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Immunogenic properties of nickel-doped maghemite nanoparticles and the implication for cancer immunotherapy by Lenka Rajsiglova, Michal Babic, Katerina Krausova, Pavol Lukac, Katerina Kalkusova, Pavla Taborska, Ludek Sojka, Jirina Bartunkova, Dmitry Stakheev, Luca Vannucci, Daniel Smrz

“…Nanoparticles are commonly used in diagnostics and therapy. They are also increasingly being implemented in cancer immunotherapy because of their ability to deliver drugs and modulate the immune system. …”
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Time to recovery of COVID-19 patients and its predictors: a retrospective cohort study in HUCSH, Sidama, Ethiopia by Ali B. Anteneh, Zeytu Gashaw Asfaw

“…Methods Study at Hawassa University Comprehensive Speciality Hospital COVID-19 quarantine and therapy facility in Ethiopia (Sep 24, 2020 - Nov 26, 2021) with 804 patients. …”
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Acute Stroke in northern Portugal: outcomes and characteristics of patients in a Medical-Surgical Emergency Department by Sandra Domingues, Tiago Barros, João Correia, Arlindo Cruz, Nuno Araújo, Liliana Silva

“…Age >70 years (OR 1.8, 95% CI: 1.3-2.5) and arrival within 3 hours (OR 2.3, 95% CI: 1.7-3.1) predicted reperfusion therapy. Female patients surpassed males in 2023 (51.01% vs 48.99%). …”
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Comprehensive analysis of ESCRT transcriptome-associated signatures and identification of the regulatory role of LMO7-AS1 in osteosarcoma by Shibing Zhao, Dasheng Tian, Fei Huang, Lei Wang, Jinhao Cheng, Zhitao He, Qitian Shen, Shuai Liang, Deliang Gong, Jun Liu, Chengfeng Yi, Chun Zhang, Erbao Bian, Juehua Jing, Tao Wang

“…The endosomal sorting complex required for transport (ESCRT) is important for the development and progression of cancer and may be a significant target for cancer therapy. First, we built a prognostic signature using 7 ESCRT-related genes (ERGs) to predict OS patient prognosis. …”
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Pulmonary Artery Intimal Sarcoma Diagnosed Preoperatively by Endovascular Biopsy and Treated via Right Pneumonectomy and Pulmonary Arterioplasty by Daiki Kato, Shohei Mori, Eriko Harada, Rintaro Shigemori, Takamasa Shibazaki, Hideki Matsudaira, Jun Hirano, Hirokazu Ashida, Hiroko Kimura, Michio Yoshitake, Takashi Kunihara, Takashi Ohtsuka

“…Pulmonary artery thromboembolism was suspected, and anticoagulation therapy was administered. However, the defect in the pulmonary artery did not improve. …”
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In vitro and in silico Anti-diabetes mechanism of phytochemicals from Curculigo pilosa and its pharmacokinetic profiling via α-amylase inhibition by Damilola A. Omoboyowa, Temitope C. Aribigbola, Simbo T. Akinsulure, Damilola S. Bodun, Ezekiel A. Olugbogi, Ebenezer A. Oni

“…Curculigo pilosa is traditionally used as herbal medication as anti-diabetes therapy but its mechanism of action is yet to be explored. …”
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Medication Belief and Adherence among Patients with Epilepsy by Yirga Legesse Niriayo, Abraham Mamo, Kidu Gidey, Gebre Teklemariam Demoz

“…Medication adherence and belief are crucial to achieving the desired goal of therapy in epileptic patients. However, there is a lack of study regarding medication adherence and belief in our setting. …”
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Intravenous Administration of Bone Marrow-Derived Mesenchymal Stem Cells Induces a Switch from Classical to Atypical Symptoms in Experimental Autoimmune Encephalomyelitis by Mónica Kurte, Javiera Bravo-Alegría, Alexander Torres, Vania Carrasco, Cristina Ibáñez, Ana María Vega-Letter, Catalina Fernández-O’Ryan, Carlos E. Irarrázabal, Fernando E. Figueroa, Rodrigo A. Fuentealba, Claudia Riedel, Flavio Carrión

“…Potent immunosuppressive and regenerative properties of mesenchymal stem cells (MSCs) position them as a novel therapy for autoimmune diseases. This research examines the therapeutic effect of MSCs administration at different disease stages in experimental autoimmune encephalomyelitis (EAE). …”
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Estimating hip impact velocity and acceleration from video-captured falls using a pose estimation algorithm by Reese Michaels, Tiago V. Barreira, Stephen N. Robinovitch, Jacob J. Sosnoff, Yaejin Moon

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Efficiency and safety of HAIC combined with lenvatinib and tislelizumab for advanced hepatocellular carcinoma with high tumor burden: a multicenter propensity score matching analys... by Zhonghua Zhao, Xiongying Jiang, Shiping Wen, Yanzhang Hao

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