Trend of Use of Quinolone Antibiotics in Community-Acquired Pneumonia by Kadir Burak AKGÜN, Emel CEYLAN, Mehmet KARADAĞ, Merve AYIK TÜRK

“…Pulmonologists were more likely to prescribe quinolones in cases of unresponsiveness to previous beta-lactam therapy and complicated pneumonia than nonpulmonologists (p=0.013, p=0.044, respectively). …”
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Novel protein-based prognostic signature linked to immunotherapeutic efficiency in ovarian cancer by Shuo-Fu Chen, Liang-Yun Wang, Yi-Sian Lin, Cho-Yi Chen

“…A key obstacle is the lack of reliable biomarkers to identify patients who would benefit significantly from the therapy. While conventional clinicopathological factors have exhibited limited efficacy as prognostic indicators in ovarian cancer, multi-omics profiling presents a promising avenue for comprehending the interplay between the tumor and immune components. …”
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A novel cytoprotective organ perfusion platform for reconstructing homeostasis of DCD liver while alleviating IRI injury by Tingting Lan, Mingxing Yu, Tao Ming, Hong Wang, Juan Deng, Shuhan Cheng, Zhongyang Shen, Deling Kong

“…The development of BBGs demonstrates the feasibility of recreating physiological liquid–gas circulation in vitro, offering an alternative platform for isolated organ perfusion, especially for applications involving cell therapy.…”
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Area under the Curve-Based Dosing of Vancomycin in Critically Ill Patients Using 6-Hour Urine Creatinine Clearance Measurement by Bita Shahrami, Farhad Najmeddin, Saeideh Ghaffari, Atabak Najafi, Mohammad Reza Rouini, Mojtaba Mojtahedzadeh

“…The area under the curve- (AUC-) guided vancomycin dosing is the best strategy for individualized therapy in critical illnesses. Since AUC can be calculated directly using drug clearance (CLvan), any parameter estimating CLvan will be able to achieve the goal of 24-hour AUC (AUC24 h). …”
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Psychological aspects of patients with breast cancer depending on the presence of visible postoperative defect by A. D. Zikiryakhodzhaev, M. V. Ermoschenkova, N. A. Sirota, B. A. Fetisov

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Clinical Outcomes of “U” Route Transforaminal Percutaneous Endoscopic Lumbar Discectomy in Chronic Pain Patients with Lumbar Spinal Stenosis Combined with Disc Herniation by Binbin Wu, Xinyi Tian, Ce Shi, Chenchen Jiang, Jing Zhang, Gonghao Zhan, Danli Xie

“…Complications of dural tear, nerve root, or dysesthesia were reported in 5 patients, and all recovered after conservative therapy. The scores of pain catastrophizing were reduced after operation (p<0.001), but no significance of BDI was found between patients and healthy controls (p>0.05). …”
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Simplified Medication Adherence Questionnaire (SMAQ) for People Living With HIV in a National Hospital in Mexico: Instrument Validation Study by Luis Eduardo Del Moral Trinidad, Luz Alicia González Hernández, Jaime Federico Andrade Villanueva, Pedro Martínez-Ayala, Adriana Valle Rodríguez, Vida Veronica Ruíz Herrera, José Adán Vizcaíno Résendiz, Melva Guadalupe Herrera Godina, Sergio Dominguez-Lara

“… BackgroundAdherence to antiretroviral therapy is a critical component in achieving viral suppression in people living with HIV in addition to increasing overall quality of life. …”
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Vonoprazan-Based Regimen Is More Useful than PPI-Based One as a First-Line Helicobacter pylori Eradication: A Randomized Controlled Trial by Masafumi Maruyama, Naoki Tanaka, Daisuke Kubota, Masayuki Miyajima, Takefumi Kimura, Koujiro Tokutake, Ryujiro Imai, Toru Fujisawa, Hiromitsu Mori, Yoshiaki Matsuda, Shuichi Wada, Akira Horiuchi, Kendo Kiyosawa

“…VPZ-based regimen is more useful than that PPI-based regimen as a first-line H. pylori eradication therapy.…”
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Amoxicillin/Clavulanic Acid for the Treatment of Odontogenic Infections: A Randomised Study Comparing Efficacy and Tolerability versus Clindamycin by Archiel Launch Tancawan, Maria Noemi Pato, Khamiza Zainol Abidin, A. S. Mohd Asari, Tran Xuan Thong, Puja Kochhar, Chandra Muganurmath, Monique Twynholm, Keith Barker

“…The primary endpoint was percentage of subjects achieving clinical success (composite measure of pain, swelling, fever, and additional antimicrobial therapy required) at the end of treatment. Results. …”
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Persistent Nasal Skin Lesions in Pemphigus Patients and the Role of Methotrexate in Treatment: A Case Series Study by Mohamad Reza Kavyani, Maryam Daneshpazhooh, Sama Heidari, Navid Namakizadeh Esfahani, Sarina Ahmadian, Arghavan Azizpour, Kamran Balighi

“…Out of the 8 pemphigus vulgaris (PV) patients who underwent RTX treatment, a total of 18 treatment sessions were carried out. Following RTX therapy, significant improvements in the nasal lesions were observed after 11 (61.1%) sessions, with 8 patients (44.4%) achieving complete resolution within 6 months. …”
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Association of dopamine receptor D2 -141C insertion/deletion and dopamine beta-hydroxylase 19 bp insertion/deletion polymorphisms with schizophrenia: A case-control study in the ea... by Boukhenaf Yasmina, Sariyah Ayachi Ouarda, Achou Rayene, Iness Bernou Amina, Zohra Madoui Fatima, Sifi Karima, Larbi Rezgoun Mohamed

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Intraoperative Hyperspectral Imaging Predicts Early Allograft Dysfunction and Overall Survival in Liver Transplantation by Andri Lederer, MD, Antonia Alina Geisler, MD, Robert Sucher, MD, Daniel Seehofer, MD, Hans-Michael Hau, MD, Uwe Scheuermann, PD, Sebastian Rademacher, MD

“…LT is a well-established therapy for acute and chronic liver diseases, with excellent outcomes. …”
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Biological Characteristics of Fluorescent Superparamagnetic Iron Oxide Labeled Human Dental Pulp Stem Cells by Liang Ma, Ming-wei Li, Yu Bai, Hui-hui Guo, Sheng-chao Wang, Qing Yu

“…These data demonstrate that MIRB is a promising candidate for hDPSCs tracking in hDPSCs based dental pulp regeneration therapy.…”
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Synchronous clonally related anaplastic large cell lymphoma and malignant histiocytosis by Mirvate Harb, Tom Abrassart, Laurent Dewispeleare, Pierre Sidon, Natacha Dirckx, Anne-laure Trepant, Julie Castiaux, Pierre Heimann, Jean-Francois Emile, Hussein Farhat

“…Considering the rarity of such occurrences, the use of histiocytosis targeted therapy alongside conventional lymphoma treatment warrants consideration in such a context.…”
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Baseline FIB‐4 May Be a Risk Factor of Recurrence After SBRT in Patients With HBV‐Related Small HCC by Zhan Zeng, Yifan Han, Wengang Li, Hongyu Chen, Ning Lin, Yanyan Yu, Xiaoyuan Xu

“…ABSTRACT Aims Exploring fibrosis index‐4 (FIB‐4)'s predictive value for HBV‐related hepatocellular carcinoma (HCC) in assessing recurrence following stereotactic body radiation therapy (SBRT) in patients with HBV‐related HCC. Methods HBV‐related HCC patients who underwent SBRT were retrospectively enrolled from March 2012 to March 2020. …”
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Predictors of plasma HDL-C concentrations in the Coronary Artery Risk Development in Young Adults (CARDIA) study by James M. Shikany, John R. Bassler, Jared P. Reis, Pamela J. Schreiner, David T. Redden, John T. Wilkins, Cora E. Lewis

“…Several factors were positively associated with HDL-C longitudinally in both women and men: age, self-identified Black race, alcohol intake, physical activity, and energy intake, along with sex-specific associations with current oral contraceptive use, current hormone therapy, and post-menopausal status (women only), and homeostasis model assessment-estimated insulin resistance (HOMA-IR) (men only). …”
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Maraviroc/cisplatin combination inhibits gastric cancer tumoroid growth and improves mice survival by Bárbara Mora-Lagos, María Elena Reyes, Lorena Lobos-Gonzalez, Matías del Campo, Kurt Buchegger, Louise Zanella, Ismael Riquelme, Carmen Gloria Ili, Priscilla Brebi

“…Conclusions This finding suggests that MVC/CDDP combination could be a potential complementary therapy for GC.…”
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Role of Tailored Timing and Frequency Prompts on the Efficacy of an Internet-Delivered Stress Recovery Intervention for Health Care Workers: Randomized Controlled Trial by Auguste Nomeikaite, Odeta Gelezelyte, Maria Böttche, Gerhard Andersson, Evaldas Kazlauskas

“… BackgroundPrompts offer a promising strategy to promote client engagement in internet-delivered cognitive behavioral therapy (ICBT). However, if the prompts do not meet the needs of clients, they can potentially be more obtrusive rather than helpful. …”
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A Research Synthesis of Therapeutic Interventions for Whiplash-Associated Disorder (WAD): Part 5 – Surgical and Injection-Based Interventions for Chronic WAD by Robert W Teasell, J Andrew McClure, David Walton, Jason Pretty, Katherine Salter, Matthew Meyer, Keith Sequeira, Barry Death

“…A systematic review was conducted to evaluate the strength of evidence associated with various WAD therapies. Multiple databases (including Web of Science, EMBASE and PubMed) were searched to identify all studies published from January 1980 through March 2009 that evaluated the effectiveness of any well-defined treatment for acute (less than two weeks), subacute (two to 12 weeks) or chronic (more than 12 weeks) WAD. …”
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Highlights of the Fourth Canadian Symposium on Hepatitis C: Moving towards a National Action Plan by Selena M. Sagan, Benoit Dupont, Jason Grebely, Mel Krajden, Sonya A. MacParland, Jennifer F. Raven, Sahar Saeed, Jordan J. Feld, D. Lorne Tyrrell, Joyce A. Wilson

“…In 2015, the release of well-tolerated, short course treatments (~12 weeks) able to cure the majority of treated HCV patients revolutionized HCV therapy. However, treatment is extremely costly and puts a significant burden on the Canadian healthcare system. …”
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