Plasma proteome fingerprint in kidney diseases by Kirill S. Nikolsky, Arthur T. Kopylov, Valeriya I. Nakhod, Natalia V. Potoldykova, Dmitry V. Enikeev, Tatiana V. Butkova, Liudmila I. Kulikova, Kristina A. Malsagova, Vladimir R. Rudnev, Denis V. Petrovskiy, Alexander A. Izotov, Anna L. Kaysheva

“…Expensive renal replacement therapy options, such as dialysis or kidney transplant, are required for end-stage kidney disease. …”
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Steroid use for established bronchopulmonary dysplasia: study protocol for a systematic review and meta-analysis by Roy K Philip, Joanna Seliga-Siwecka, Eduardo Villamor, Maria Pierro, Niazy Al Assaf, Sabina Strashun, Roberto Chioma, Kinga Zielińska, Krzysztof Włodarczyk

“…Steroids are used to treat established BPD in an attempt to reduce mortality, and length of stay and home oxygen therapy, both of which associated with high levels of parental stress and healthcare costs. …”
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Severe Guillain-Barré syndrome with concurrent optic neuritis in a pediatric patient: a case report by Xin Xue, Yingcun Bao, Yakun Yu, Qun Li, Mei Liu, Xiaoling Li

“…Neurophysiological studies indicated widespread demyelinating and axonal damage.Interventions and outcomesThe patient received intravenous immunoglobulin (IVIG) therapy, high-dose corticosteroids, and, given the severe progression, rituximab. …”
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The Effects of Hyperacute Serum on the Elements of the Human Subchondral Bone Marrow Niche by Melinda Simon, Bálint Major, Gabriella Vácz, Olga Kuten, István Hornyák, Adél Hinsenkamp, Dorottya Kardos, Marcell Bagó, Domonkos Cseh, Adrienn Sárközi, Denes Horvathy, Stefan Nehrer, Zsombor Lacza

“…Mesenchymal stem cells (MSCs) are widely used in laboratory experiments as well as in human cell therapy. Their culture requires animal sera like fetal calf serum (FCS) as essential supplementation; however, animal sera pose a risk for clinical applications. …”
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Effect of PCSK9 Inhibitor on Blood Lipid Levels in Patients with High and Very-High CVD Risk: A Systematic Review and Meta-Analysis by Yue Zhang, Yanrong Suo, Lin Yang, Xiaolu Zhang, Qun Yu, Miao Zeng, Wenlan Zhang, Xijuan Jiang, Yijing Wang

“…Addition of PCSK9 inhibitors to standard therapy resulted in definite improvement in blood lipid levels compared with therapies that did not include them.…”
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RELAPSES AFTER RADICAL SUBCUTANEOUS/SKIN-SPARING MASTECTOMY WITH SIMULTANEOUS RECONSTRUCTION IN BREAST CANCER by A. D. Zikiryakhodzhayev, E. A. Rasskazova, A. Yu. Tukmakov, I. M. Shirokikh

“…In 9 (1,7 ± 0,6%) of patients diagnosed with a recurrence of breast cancer, herewith in 5 cases of local and in 4 cases of regional recurrence (metastases in the infraclavicular lymph nodes).Treatment of recurrences of breast cancer was as follows: in two cases polychemotherapy courses were conducted, in 6 cases operations were performed — excision of relapse in the breast (3) and subclavian lymphadenectomy (1), remov­al of the reconstructed gland (2), in 1 case — radiation therapy.In 13% relapses of breast cancer were diagnosed at stage III of breast cancer, the lowest percentage of relapse 0.7% at stage III. …”
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Endothelial AGGF1 promotes retinal angiogenesis by coordinating TNFSF12/FN14 signalling by Ying Cheng, Man Zhang, Chenguang Li, Long Su, Lingli Fu, Shi Wu, Chaofei Xu, Bei Sun, Liming Chen

“…Overall, we elucidate the mechanism underlying pathological retinal angiogenesis involved in endothelial AGGF1-dependent events and highlight a therapy for the effective treatment of ischaemic retinopathy.…”
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Psychosocial and pharmacologic interventions for problematic methamphetamine use: Findings from a scoping review of the literature. by Mona Hersi, Kim Corace, Candyce Hamel, Leila Esmaeilisaraji, Danielle Rice, Nicole Dryburgh, Becky Skidmore, Gary Garber, Amy Porath, Melanie Willows, Paul MacPherson, Beth Sproule, Jorge Flores-Aranda, Chandlee Dickey, Brian Hutton

“…Amongst primary studies, many interventions were assessed by only single studies; contingency management was the therapy most commonly associated with evidence of potential effectiveness, while bupropion and modafinil were analogously the most common pharmacologic interventions. …”
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ESPGHAN and NASPGHAN 2024 protocol for paediatric functional constipation treatment guidelines (standard operating procedure) by Marc A Benninga, Morris Gordon, Nikhil Thapar, Osvaldo Borrelli, Vassiliki Sinopoulou, Merit Tabbers, Anil Darbari, Julie Khlevner, Anna de Geus, Marcin Banasiuk, Mary Boruta, Dawn Dore-Stites, Michelle Gould, Juliette Hawa, Kirsten Brooke Jones, Alexandra Kilgore, Hayat Mousa, Samuel Nurko

“…There is a significant range of therapies available to healthcare professionals for this condition, with many novel or recently studied. …”
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Influence of strength and power training on the rate of force development, peak force and functional mobility in elderly people with Parkinson's disease: a randomized controlled tr... by Késia Maísa do Amaral Felipe, Késia Maísa do Amaral Felipe, Patrícia de Aguiar Yamada, Tamires Meneghetti, Flávia Roberta Faganello-Navega, Flávia Roberta Faganello-Navega

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Meta-Analysis of Randomized Trials: Efficacy and Safety of Colchicine for Secondary Prevention of Cardiovascular Disease by Elie Akl, Nazanin Sahami, Christopher Labos, Jacques Genest, Ali Zgheib, Nicolo Piazza, Sanjit Jolly

“…Conclusions. Colchicine therapy may reduce the risk of future cardiovascular events in patients with established CAD; however, there remains a concern about non-CV mortality. …”
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Intracellular iron accumulation throughout the progression of sepsis influences the phenotype and function of activated macrophages in renal tissue damage by Mira Hanna, Ahmed M. A. Akabawy, Mohamed Mansour Khalifa, Mohamed Mansour Khalifa, Marawan Abd Elbaset, Reda Abdelnasser Imam, Hanan Seddiek

“…Finally, early introduced therapy to target free iron during sepsis is a proposed novel solution for protecting the renal tissue from acute injury due to macrophage activation that may end up with chronic kidney injury, if not mortality.…”
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Evaluation of the effect of Irritrol as final irrigant against Staphylococcus epidermidis: an in Vitro Study. by Hezha Saadi Hassan, Diyar Khalid Bakr

“…Staphylococcus epidermidis is one of the most isolated or detected species from oral infections, including marginal periodontitis, infected root canals, peri‐radicular, peri‐implantitis, and also detected in cases of failed endodontic therapy. In order to prevent endodontic treatment, failure irrigation is mandatory for the effective removal of smear, pulp tissue, smear layer,and microorganisms. …”
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Real-World Treatment Patterns, Outcomes, and Healthcare Resource Utilization in Relapsed or Refractory Multiple Myeloma: Evidence from a Medical Record Review in France by Huamao Mark Lin, Keith L. Davis, James A. Kaye, Katarina Luptakova, Saurabh P. Nagar, Mohamad Mohty

“…These findings may inform economic evaluations of RRMM therapies.…”
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The Use and Impact of Virtual Reality Programs Supported by Aromatherapy for Older Adults: A Scoping Review by Lillian Hung, Joey Wong, Karen Lok Yi Wong, Rynnie Cin Ee Son, Mary Van, W. Ben Mortenson, Angelica Lim, Jennifer Boger, Christine Wallsworth, Yong Zhao

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A Liquid Chromatography with Tandem Mass Spectrometry-Based Proteomic Analysis of Primary Cultured Cells and Subcultured Cells Using Mouse Adipose-Derived Mesenchymal Stem Cells by Yoshiki Nakashima, Saifun Nahar, Chika Miyagi-Shiohira, Takao Kinjo, Naoya Kobayashi, Issei Saitoh, Masami Watanabe, Jiro Fujita, Hirofumi Noguchi

“…Adipose-derived mesenchymal stem cells (MSC-ATs) are representative cell sources for cell therapy. However, how cell stress resulting from passage influences the MSC-AT protein expression has been unclear. …”
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Intracranial germ cell tumors: advancement in genomic diagnostics and the need for novel therapeutics by Kee Kiat Yeo, Kee Kiat Yeo, Joanna Gell, Joanna Gell, Joanna Gell, Girish Dhall, Girish Dhall, Ching Lau, Ching Lau, Ching Lau

“…Development of targeted therapeutics against KIT has led to the prospect of targeted therapy in germinoma. Other treatment modalities being considered for clinical development include immunotherapy and the use of immune checkpoint inhibitors, especially in NGGCT. …”
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Fecal Microbiota Transplantation: A New Therapeutic Attempt from the Gut to the Brain by Hao-Ming Xu, Hong-Li Huang, You-Lian Zhou, Hai-Lan Zhao, Jing Xu, Di-Wen Shou, Yan-Di Liu, Yong-Jian Zhou, Yu-Qiang Nie

“…Fecal microbiota transplantation (FMT) is a biological therapy that entails transferring the gut microbiota from healthy individuals to patients in order to reconstruct the intestinal microflora in the latter. …”
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Matched Unrelated Donor Hematopoietic Cell Transplantation: Increased Usage and Improvements in Clinical Outcomes in Canada by Matthew D. Seftel, Grace Musto, David Allan, Oliver Bucher, Kevin Hay, Ivan Pasic, Tony Truong, Kristjan Paulson

“…We investigated temporal trends in MUD compared to MRD HCT from 2000 to 2019 using data reported to the Cell Therapy and Transplant Canada (CTTC) Registry. Of 7571 first allogeneic HCTs between 2000 and 2019, the proportion of MUD HCTs rose from 35.1% to 56.3% in the early (2000–2009) and later (2010–2019) eras, respectively. …”
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Immunohistochemical Coexpression of Epithelial Cell Adhesion Molecule and Alpha-Fetoprotein in Hepatocellular Carcinoma by Leonardo do Prado Lima, Carla Jorge Machado, João Bernardo Sancio Rocha Rodrigues, Leonardo de Souza Vasconcellos, Eduardo Paulino Junior, Paula Vieira Teixeira Vidigal, Vivian Resende

“…A considerable number of patients with EpCAM+ HCC would benefit from a specific target therapy.…”
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