Showing 17,241 - 17,260 results of 20,793 for search '"Therapy"', query time: 0.14s Refine Results
  1. 17241

    Complex approach to the prevention and treatment of progressive myopia in school children by Tarutta E.P, Iomdina E.N, Tarasova N.A., Markosyan G.A., Maksimova M.V.

    Published 2018-07-01
    “…<br> <br> Moscow Research Institute of Eye Diseases named after Helmholtz<br> <br> Effective prevention of progressive myopia as a multifactorial ophthalmopathology requires a comprehensive approach, including various methods of targeted optical correction, functional stress and drug therapy. The review presents local and systemic drug support, improving the performance of the ciliary muscle and hemodynamics of the myopic eye, which have antioxidant and vasoconstrictor effects. …”
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  2. 17242

    Beyond Hormone Receptors: liquid biopsy tools to unveil new clinical meanings and empower therapeutic decision-making in Luminal-like metastatic breast cancer by Brenno Pastò, Riccardo Vida, Arianna Dri, Lorenzo Foffano, Serena Della Rossa, Lorenzo Gerratana, Fabio Puglisi

    Published 2025-02-01
    “…Luminal-like tumors primarily benefit from a first line treatment strategy combining endocrine therapy and cyclin-dependent kinase 4/6 inhibitors. …”
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  3. 17243

    TERT de novo mutation-associated dyskeratosis congenita and porto-sinusoidal vascular disease: a case report by Ge Yu, Guijie Xin, Xu Liu, Wanyu Li, Chen Shao, Runping Gao

    Published 2025-01-01
    “…After 6 months, he has moderate iron deficiency anemia and has started receiving polysaccharide iron complex therapy. Conclusion When discovering reticular rash and unknown portal hypertension, it is necessary to perform whole exome sequencing and chromosome length testing to clarify the possibility of dyskeratosis congenita/telomere biology disorder with porto-sinusoidal vascular disease.…”
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  4. 17244

    Acupuncture for patients with type 2 diabetes mellitus with dry eye: protocol for a systematic review and meta-analysis by Ting Li, Xin Xu, Juan Wei, Qingbo Wei, Zhouyu Xie, Xiangyu Bian, Yunchuan Wu

    Published 2022-06-01
    “…Acupuncture is a widely used alternative therapy. Indeed, randomised trials have found that acupuncture confers a definite therapeutic effect on patients with T2DM with dry eye. …”
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  5. 17245
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  7. 17247

    Current conceptions and promising tools to prevent cataractogenesis by M.A. Kovalevskaya, Yu.V. Vladimirova, L.A. Filina, V.L. Kokorev

    Published 2021-03-01
    “…&nbsp;Burdenko Voronezh State Medical University, Voronezh, Russian Federation</b> </p> <p> <i>This paper highlights current pharmacotherapeutic modalities for various metabolic disorders which result in cataract. This therapy is preferable for the prevention and treatment of lens opacities due to less financial costs and ease of use. …”
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  8. 17248

    Protocol of a randomised trial of teriparatide followed by zoledronic acid to reduce fracture risk in adults with osteogenesis imperfecta by Jennifer Walsh, Catriona Keerie, Stuart H Ralston, Christopher J Weir, Muhammad K Javaid, WAYNE LAM, Bente L Langdahl, Jannie D Hald, Patricia Osborne

    Published 2023-11-01
    “…The Treatment of Osteogenesis Imperfecta with Parathyroid Hormone and Zoledronic Acid trial will determine if therapy with teriparatide (TPTD) followed by zoledronic acid (ZA) can reduce the risk of clinical fractures in OI.Methods and analysis Individuals aged ≥18 years with a clinical diagnosis of OI are eligible to take part. …”
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  9. 17249

    Effectiveness of mental health interventions for older adults in South Asia: A scoping review. by Hoimonty Mazumder, Farah Faizah, Easter Protiva Gain, Irfath Sharmin Eva, Kaniz Ferdouse Mou, Nobonita Saha, Farzana Rahman, Jyoti Das, A M Khairul Islam, Fazilatun Nesa, M Mahbub Hossain

    Published 2023-01-01
    “…Across studies, mental health interventions can be broadly categorized into the following types- 1) traditional Yoga, Tai chi, or other meditative movements; 2) behavioral, occupational, or learning-based interventions; 3) tech-based interventions; 4) music therapy; and 5) new healthcare model. The evidence was predominantly based on India (n = 16), whereas three articles were identified from Pakistan. …”
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  10. 17250

    Metronidazole-Induced Pancreatitis: Is There Underrecognition? A Case Report and Systematic Review of the Literature by Ibrahim Youssef, Naba Saeed, Mohammad El Abdallah, Kara Huevelhorst, Kais Zakharia

    Published 2019-01-01
    “…Symptoms usually start within 2-7 days of starting the medication and usually resolve 2-5 days after discontinuation of therapy and pancreatitis treatment. The most common causative dose was 1-1.5 g/day. …”
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  11. 17251

    Feasibility of home-based transcranial direct current stimulation combined with personalized word retrieval for improving naming in primary progressive aphasia by Allan George, Eric McConathey, Amy Vogel-Eyny, Elizabeth Galletta, Giuseppina Pilloni, Leigh Charvet

    Published 2025-02-01
    “…Background/ObjectivesPrimary progressive aphasia (PPA) is managed with speech-language therapy (SLT) to slow language decline. Pairing transcranial direct current stimulation (tDCS) with SLT can enhance its effects. …”
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  12. 17252

    Effectiveness of dupilumab treatment against refractory eosinophilic chronic rhinosinusitis by Daiki Nakashima, MD, Tsuguhisa Nakayama, MD, PhD, Shunsuke Minagawa, MD, PhD, Tetsuya Adachi, MD, PhD, Chieko Mitsuyama, MD, Yoko Shida, MD, Tsuneya Nakajima, MD, PhD, Shin-ichi Haruna, MD, PhD, Yoshinori Matsuwaki, MD, PhD

    Published 2025-05-01
    “…Nasal polyps had disappeared in 91 patients (85.9%) at 12 months, and there was improvement in all end points; 104 patients (97.2%) were able to eliminate systemic corticosteroid therapy. In the multivariate analysis, male sex was significantly associated with patients who did not show an improvement to 0 in the NPS and computed tomography score (odds ratios: 7.58 and 2.45; P = .01 and P = .04, respectively). …”
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  13. 17253
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  16. 17256

    Comparison of Inhibitor and Substrate Selectivity between Rodent and Human Vascular Adhesion Protein-1 by Ryo Kubota, Michael J. Reid, Kuo Lee Lieu, Mark Orme, Christine Diamond, Niklas Tulberg, Susan H. Henry

    Published 2020-01-01
    “…Inhibition of VAP-1 oxidative deamination has become an attractive target for anti-inflammatory therapy with demonstrated efficacy in rodent models of inflammation. …”
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  17. 17257

    Discrete vulnerability to pharmacological CDK2 inhibition is governed by heterogeneity of the cancer cell cycle by Vishnu Kumarasamy, Jianxin Wang, Michelle Roti, Yin Wan, Adam P. Dommer, Hanna Rosenheck, Sivasankar Putta, Alec Trub, John Bisi, Jay Strum, Patrick Roberts, Seth M. Rubin, Costakis Frangou, Karen McLean, Agnieszka K. Witkiewicz, Erik S. Knudsen

    Published 2025-02-01
    “…Abstract Cyclin dependent kinase 2 (CDK2) regulates cell cycle and is an emerging target for cancer therapy. There are relatively small numbers of tumor models that exhibit strong dependence on CDK2 and undergo G1 cell cycle arrest following CDK2 inhibition. …”
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  18. 17258

    Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors by Alessandro Papale, Ilaria Maria Morella, Marzia Tina Indrigo, Rick Eugene Bernardi, Livia Marrone, Francesca Marchisella, Andrea Brancale, Rainer Spanagel, Riccardo Brambilla, Stefania Fasano

    Published 2016-08-01
    “…Furthermore, a screening of small therapeutics currently in clinical trials for cancer therapy revealed PD325901 as a brain-penetrating drug that blocks ERK signalling in the nanomolar range. …”
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  19. 17259

    Metabolic Syndrome in People Living with Human Immunodeficiency Virus: An Assessment of the Prevalence and the Agreement between Diagnostic Criteria by Kim Anh Nguyen, Nasheeta Peer, Anniza de Villiers, Barbara Mukasa, Tandi E. Matsha, Edward J. Mills, Andre Pascal Kengne

    Published 2017-01-01
    “…Median values were 38 years (age), 5 years (diagnosed HIV duration), and 392 cells/mm3 (CD4 count), and 93% of the participants were on antiretroviral therapy (ART). MetS prevalence was 28.2% (95%CI: 25–31.4), 26.5% (23.3–29.6), and 24.1% (21–27.1) by the JIS, IDF, and ATPIII 2005 criteria, respectively. …”
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  20. 17260

    Study on SHP2 Conformational Transition and Structural Characterization of Its High-Potency Allosteric Inhibitors by Molecular Dynamics Simulations Combined with Machine Learning by Baerlike Wujieti, Mingtian Hao, Erxia Liu, Luqi Zhou, Huanchao Wang, Yu Zhang, Wei Cui, Bozhen Chen

    Published 2024-12-01
    “…Aberrant activation and mutations of SHP2 are associated with tumor growth and immune suppression, thus making it a potential target for cancer therapy. Initially, researchers sought to develop inhibitors targeting SHP2’s catalytic site (protein tyrosine phosphatase domain, PTP). …”
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