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16961
Electrical Stimulation of the Ear, Head, Cranial Nerve, or Cortex for the Treatment of Tinnitus: A Scoping Review
Published 2016-01-01“…It is often associated with hearing loss and is thought to result from abnormal neural activity at some point or points in the auditory pathway, which is incorrectly interpreted by the brain as an actual sound. Neurostimulation therapies therefore, which interfere on some level with that abnormal activity, are a logical approach to treatment. …”
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16962
Structural insights into antibody-based immunotherapy for hepatocellular carcinoma
Published 2025-01-01“…A crucial aspect of advancing these therapies lies in understanding the structural interactions between antibodies and their targets. …”
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16963
Stem Cell Applications in Tendon Disorders: A Clinical Perspective
Published 2012-01-01“…Tendinopathy is treated by exercises, injection therapies, shock wave treatments or surgical tendon debridement. …”
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Mesenchymal Stem Cells as Therapeutics Agents: Quality and Environmental Regulatory Aspects
Published 2016-01-01“…Mesenchymal stem cells (MSCs) are one of the main stem cells that have been used for advanced therapies and regenerative medicine. To carry out the translational clinical application of MSCs, their manufacturing and administration in human must be controlled; therefore they should be considered as medicine: stem cell-based medicinal products (SCMPs). …”
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Immune Checkpoint Modulators: An Emerging Antiglioma Armamentarium
Published 2016-01-01“…Immune checkpoints have come to the forefront of cancer therapies as a powerful and promising strategy to stimulate antitumor T cell activity. …”
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16969
Galectins as New Prognostic Markers and Potential Therapeutic Targets for Advanced Prostate Cancers
Published 2013-01-01“…A better understanding of multimolecular interactions involved in tumor dissemination is required to identify new effective therapies for advanced prostate cancer (PCa). Several groups investigated protein-glycan interactions as critical factors for crosstalk between prostate tumors and their microenvironment. …”
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USP35 promotes the growth of ER positive breast cancer by inhibiting ferroptosis via BRD4-SLC7A11 axis
Published 2025-01-01“…Abstract Anti-estrogen endocrine therapies greatly improve survival of estrogen receptor positive (ER + ) breast cancer. …”
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16972
Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature
Published 2024-01-01“…Immunotherapy is preferred to other cancer therapies, offering precise targeting of malignant cells while simultaneously strengthening the immune system’s complex responses. …”
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Intra-Arterial Chemotherapy with Doxorubicin and Cisplatin Is Effective for Advanced Hepatocellular Cell Carcinoma
Published 2014-01-01“…Advanced hepatocellular carcinoma (HCC) remains a fatal disease even in the era of targeted therapies. Intra-arterial chemotherapy (IACT) can provide therapeutic benefits for patients with locally advanced HCC who are not eligible for local therapies or are refractory to targeted therapies. …”
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16975
Fidaxomicin: A Novel Agent for the Treatment of Clostridium difficile Infection
Published 2015-01-01“…BACKGROUND: Due to the limitations of existing treatment options for Clostridium difficile infection (CDI), new therapies are needed.…”
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16976
From Global Insights to National Impact: Advancing Cardio-Oncology in Iraq
Published 2024-12-01“… Cancer remains a leading cause of mortality and morbidity worldwide. Advances in cancer therapies—including immunotherapies (e.g., checkpoint inhibitors, gene-targeted therapies), antibody-based cancer toxins, chemotherapy, radiotherapy, and surgery—have significantly improved survival rates 1,2. …”
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16977
Stem Cells for Cartilage Repair: Preclinical Studies and Insights in Translational Animal Models and Outcome Measures
Published 2018-01-01“…Due to the restricted intrinsic capacity of resident chondrocytes to regenerate the lost cartilage postinjury, stem cell-based therapies have been proposed as a novel therapeutic approach for cartilage repair. …”
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16978
Dynamic Network-Based Relevance Score Reveals Essential Proteins and Functional Modules in Directed Differentiation
Published 2015-01-01“…The induction of stem cells toward a desired differentiation direction is required for the advancement of stem cell-based therapies. Despite successful demonstrations of the control of differentiation direction, the effective use of stem cell-based therapies suffers from a lack of systematic knowledge regarding the mechanisms underlying directed differentiation. …”
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16979
Clinical Development of Biological Response Modifiers
Published 1994-01-01“…OBJECTIVE: To present perspectives on selected issues that frequently arise during the clinical development of biological response modifier (BRM) therapies.…”
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Integration of Therapeutic Components in the Rehabilitation of Patients with Parkinson’s Disease
Published 2020-06-01“…This systematic review analyzed as problem, the integration of physical therapies and therapeutic components during physical rehabilitation process. …”
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