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16861
Performance of Ultrasound in the Clinical Evaluation of Gout and Hyperuricemia
Published 2021-01-01“…Early urate-lowering therapy (ULT) should be considered in patients with gout, DCS, or tophi.…”
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16862
Accepting your Body after Cancer (ABC), a group-based online intervention for women treated for breast cancer: study protocol for a feasibility randomised controlled trial
Published 2025-01-01“…ABC participants will also take part in a weekly seven-session, group-based cognitive behavioural therapy intervention, delivered online by a psychologist and cancer support specialist. …”
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16863
The Transcription Factor SOX18 Inhibitor Small Molecule 4 Is a Potential Treatment of Cancer‐Induced Lymphatic Metastasis and Lymphangiosarcoma
Published 2025-01-01“…Further in vitro studies are warranted to investigate the mechanisms and conduct dose–response analyses to evaluate Sm4's potential as a targeted therapy for lymphangiosarcoma and cancer‐induced lymphangiogenesis in the future.…”
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16864
Transient Third-Degree Atrioventricular Block in a Dog with Addisonian Crisis
Published 2025-01-01“…Treatment for hyperkalemia was initiated immediately after admission, followed by dexamethasone sodium phosphate administration, which led to an improvement in the patient’s general condition, and the normalization of the ECG readings, after 24 h of therapy. Afterward, prednisolone (0.5 mg/kg/24 h p.o.) and desoxycorticosterone pivalate (2.2 mg/kg s.c.) were administered. …”
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16865
Comprehensive single-cell pan-cancer atlas unveils IFI30+ macrophages as key modulators of intra-tumoral immune dynamics
Published 2025-01-01“…BackgroundThe convergence of macrophage-targeted strategies with immune checkpoint blockade therapies defines a pivotal avenue in contemporary tumor therapy. …”
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16866
Identification of a Novel lincRNA-p21-miR-181b-PTEN Signaling Cascade in Liver Fibrosis
Published 2016-01-01“…In conclusion, our results disclose a novel lincRNA-p21-miR-181b-PTEN signaling cascade in liver fibrosis and suggest lincRNA-p21 as a promising molecular target for antifibrosis therapy.…”
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16867
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16868
Removable prosthesis with precision attachments for the lower jaw in lateral edentation
Published 2024-06-01“…Hence, in these scenarios the options to use the implant therapy are limited. Case report. 50-year-old female patient was referred to clinic for a full mandibula rehabilitation. …”
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16869
Mandible reconstruction after head and neck management for oral cancer: A case report and literature review
Published 2024-06-01“…The patient developed malocclusion and halitosis which was treated as late radiation tissue injury with prescribed hyperbaric oxygen therapy (HBOT). Although the procedure related to cancer was successful the mandible reduction and fixation were not enough. …”
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16870
Inhalable nanovesicles loaded with a STING agonist enhance CAR-T cell activity against solid tumors in the lung
Published 2025-01-01“…In both orthotopic lung cancer and lung metastasis model, combined therapy with CAR-T cells and aPD-L1 NVs@cGAMP potently inhibits tumor growth and prevents recurrence. …”
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16871
Small-molecule-induced ERBB4 activation to treat heart failure
Published 2025-01-01“…The neuregulin-1/ERBB4 pathway offers cardioprotective benefits, but using recombinant neuregulin-1 as therapy has limitations due to the need for intravenous delivery and lack of receptor specificity. …”
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16872
Review of Current First-Line Pharmacotherapy Strategies for Thyroid Eye Disease
Published 2025-01-01“…This paper focuses on the efficacy, protocols, and safety profiles of selenium supplementation and glucocorticoid therapy, emphasizing its central role in TED management. …”
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16873
Use of Multiple Doses of Intravenous Infusion of Umbilical Cord-Mesenchymal Stem Cells for the Treatment of Adult Patients with Severe COVID-19-Related Acute Respiratory Distress S...
Published 2023-01-01“…A single dose of IVF-UC-MSCs therapy for severe COVID-19 patients was shown to alleviate the initial ARDS severity, but have 50%–67% case-fatality rates. …”
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16874
Role of percutaneous testis biopsy in management of patients with azoospermia
Published 2020-09-01“…Was built a logistic regression model to analyze factors influencing the result, TESA / PESA, which included as independent variables the following parameters: patient age, duration of involuntary infertility, the level of sex hormones (testosterone, estradiol, luteinizing hormone, follicle-stimulating hormone, prolactin, progesterone, inhibin B), the total volume of testes, presence of varicocele, the presence of chemotherapy or radiation therapy, a history of alcohol abuse, Smoking, regular violation of the thermal mode, surgery in the inguinal and scrotal region. …”
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16875
Downregulation of VRK1 Inhibits Progression of Lung Squamous Cell Carcinoma through DNA Damage
Published 2023-01-01“…The downregulation of VRK1 significantly affected the proliferation, apoptosis, migration, and cell cycle progression of LUSC cells via DDR, suggesting that VRK1 is a suitable target for potential LUSC therapy.…”
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16876
An in-vivo herb-drug interaction study of IME-9 and glimepiride in nicotinamide-STZ-induced diabetic rats
Published 2025-05-01“…Notably, the combination treatment (GP+IME-9) significantly decreased FBGL, TC and TG levels compared to individual therapy groups, suggesting synergistic pharmacodynamic effects. …”
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16877
The role of Kegel exercises in reducing involuntary loss of urine in Overactive Bladder and Mixed Urinary Inconti-nence
Published 2025-01-01“…The participants were monitored for six months: In the first three months received only pharmacological therapy, solifenacin succinate 10 mg per day, and after this period the same group associated to the pharmacological treatment daily Kegel exercises. …”
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16878
Comparisons of Differentiation Potential in Human Mesenchymal Stem Cells from Wharton’s Jelly, Bone Marrow, and Pancreatic Tissues
Published 2015-01-01“…We compared the differential ability and the curative effect of IPCs from three types of human tissue to determine the ideal source of cell therapy for diabetes. Methods. We induced MSCs from Wharton’s jelly (WJ), bone marrow (BM), and surgically resected pancreatic tissue to differentiate into IPCs. …”
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16879
Progress towards 90-90-90 and 95-95-95 strategy implementations and HIV positivity trends in the City of Johannesburg
Published 2023-12-01“…There were significant steady increases in the number of people who knew their HIV status (slope = 0.044, p<0.001) and initiating on antiretroviral therapy (ART) (slope = 0.001, p<0.001), and significant decreases for overall HIV positivity rate (slope = –0.016, p<0.001), adolescent positivity rate (slope = –0.0087, p<0.001) and antenatal care HIV positivity rate (slope = –0.013, p<0.001). …”
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16880
Extraocular Surgical Approach for Placement of Subretinal Implants in Blind Patients: Lessons from Cochlear-Implants
Published 2015-01-01“…In hereditary retinal diseases photoreceptors progressively degenerate, often causing blindness without therapy being available. Newly developed subretinal implants can substitute functions of photoreceptors. …”
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