Prevalence of adherence and its impact on quality of life in oral anticoagulant users in Egypt: A cross-sectional study from two Egyptian university hospitals by Mohamed Terra, Amro Badr, Mohamed Baklola, Ibrahim Hegazy, Muhammed Elmanzlawey, Islam Elrakhawy, Ahmed Muhammed

“…Abstract Background Oral anticoagulant therapy (OAT) is critical for managing thromboembolic disorders, but adherence challenges significantly impact its effectiveness and patients’ quality of life (QoL). …”
Get full text

Multidrug Resistant Enteric Bacteria from Cancer Patients Admitted in Douala Laquintinie Hospital, Littoral Region of Cameroon by Michael F. Kengne, Ornella D. Tsobeng, Ballue S. T. Dadjo, Victor Kuete, Armelle T. Mbaveng

“…The increase in the number of Gram-negative infections among cancer patients, as shown in the present study, highlights the need for broad-spectrum therapy and effective planning of control programs to reduce bacterial diseases among cancer patients.…”
Get full text

Effect of low salicylate diet on clinical and inflammatory markers in patients with aspirin exacerbated respiratory disease – a randomized crossover trial by Leigh J. Sowerby, Krupal B. Patel, Crystal Schmerk, Brian W. Rotenberg, Taciano Rocha, Doron D. Sommer

“…In addition to the therapeutic routines and surgical options available, a low dietary intake of food salicylate has been suggested as adjunctive therapy for this condition. This study aimed to assess the influence of a short-term low salicylate diet on inflammatory markers in patients with AERD and whether that would result in symptomatic improvement. …”
Get full text

INTERRELATION OF PRIONS WITH NON-CODING RNAS by R. N. Mustafin, E. K. Khusnutdinova

“…Research in this direction can be the basis for targeted anti-microRNA therapy of prion diseases.…”
Get full text

Pre-existing atrial fibrillation and risk of arterial thromboembolism and death following pneumonia: a population-based cohort study by Reimar Wernich Thomsen, Christian Fynbo Christiansen, Bodil Steen Rasmussen, Lars Hvilsted Rasmussen, Jacob Gamst

“…Objectives To examine the effect of pre-existing atrial fibrillation (AF) and associated therapy on the risk of arterial thromboembolism (ATE) and death following pneumonia.Design, setting and participants Population-based cohort study (1997–2012) of 88 315 patients with first-time hospitalisation with pneumonia in Northern Denmark.Results Of the included patients (median age 73.4 years), 8880 (10.1%) had pre-existing AF. …”
Get full text

NMR metabolic profiling of the liver following administrationof alcohol andthemushroom Ganoderma lucidum in rats by M. S. Krestina, O. B. Shevelev, I. V. Koptyug, L. A. Gerlinskaya, S. E. Peltek, A. E. Akulov

“…Consequently, 1H NMR spectro­scopy can serve as a promising approach to detecting alcohol-related liver pathologies and assessing the efficiency of the therapy used.…”
Get full text

Combination chemotherapy with sintilimab for treatment of a male patient with primary pulmonary choriocarcinoma: a case report and literature review by Xiaojing Liang, Guoqing Xu, Jisong Zhang, Li Xu, Liangliang Dong, Xiaoyue Wang, Weidong Han, Enguo Chen

“…Therefore, ICIs may be a promising therapy option for patients with PPC.…”
Get full text

Acute Kidney Injury in Pediatric Treated with Vancomycin and Piperacillin-Tazobactam in Tertiary Care Hospital by Mohammed Al Nuhait, Laila C. Abu Esba, Khalid Al Harbi, Meshary Al Meshary, Rami T. Bustami

“…Vancomycin and piperacillin-tazobactam (PTZ) are commonly used as empirical therapy for patients with health care associated infections. …”
Get full text

Efficacy and safety of antifibrotic drugs for interstitial lung diseases other than IPF: A systematic review, meta-analysis and trial sequential analysis. by Mei Yang, Yuying Tan, Ting Yang, Dan Xu, Mei Chen, Lei Chen

“…<h4>Background</h4>The therapeutic role of antifibrotic therapy has been well-established in idiopathic pulmonary fibrosis (IPF). …”
Get full text

Effect and safety of ethanolamine oleate in sclerotherapy in patients with difficult-to-resect venous malformations: A multicenter, single-arm study. by Mine Ozaki, Tadashi Nomura, Keigo Osuga, Masakazu Kurita, Ayato Hayashi, Shunsuke Yuzuriha, Noriko Aramaki-Hattori, Makoto Hikosaka, Taiki Nozaki, Michio Ozeki, Junko Ochi, Shimpei Akiyama, Yasumasa Kakei, Keiko Miyakoda, Naoko Kashiwagi, Takahiro Yasuda, Yuki Iwashina, Tsuyoshi Kaneko, Kiyoko Kamibeppu, Takafumi Soejima, Kiyonori Harii

“…Prompt initiation of haptoglobin therapy led to full recovery within a month for these patients.…”
Get full text

Potentiation of Doxorubicin Cytotoxicity Utilizing Clarithromycin Loaded-PEGylated Liposomes by Islam Alfreahat MS, Hamdi Nsairat PhD, Ibrahim Deeb Aldeeb PhD, Ali Al-Samydai PhD, Walhan Alshaer PhD

Get full text

Lupus activity in lupus nephritis patients with end-stage renal disease treated with hemodialysis by Caroline Samy Morad, Shams ElDoha Galal Zaiema, Eman Ahmed Hafez, Mohammed Maher Mohammed Mohammed Mansour, Amr Elsayed Mohammed Abd-Allah Khalil, Shaymaa Gamal Arafa Hassan

“…Abstract Background Lupus nephritis is one of the major causes of ESRD, which may necessitate renal replacement therapy, especially hemodialysis. Evaluating post-HD lupus flares in LN patients is pivotal in improving their outcomes. …”
Get full text

Hyperoxia Reversibly Alters Oxygen Consumption and Metabolism by Patrick Lauscher, Sabine Lauscher, Harry Kertscho, Oliver Habler, Jens Meier

Get full text

A compound heterozygous ADAMTS13 mutation causes congenital thrombotic thrombocytopenic purpura: a case report by Yezi Huang, Lixia Zhou, Yuan Song, Wanting Zou, Aiping Tang, Si Tao, Duozhuang Tang

“…Initially diagnosed with ITP, he was treated with immunosuppressive therapy, including glucocorticoids and intravenous immunoglobulin, which provided temporary relief but failed to prevent recurrent thrombocytopenia. …”
Get full text

Prevalence, Antimicrobial Susceptibility Pattern, and Associated Factors of Urinary Tract Infections among Pregnant and Nonpregnant Women at Public Health Facilities, Harar, Easter... by Degu Abate, Dadi Marami, Shiferaw Letta

“…Regular assessment of urinary tract infections and antimicrobial resistance are recommended to provide effective therapy and thereby prevent urinary tract complications.…”
Get full text

Biofilm as a supracellular organization of pathogenic bacteria by B.P. Kuzminov, K.D. Mazhak

“…The search, synthesis, and development of drugs based on modified autoinducers of various natures can lead to a breakthrough in the field of antibacterial therapy of infectious diseases, as well as surgical purulent postoperative complications. …”
Get full text

Analysis of factors affecting the clinical management of infection in culture-negative patients following percutaneous endoscopic decompression: a retrospective study by Changpeng Qu, Haixin Wei, Hao Zhang, Zheng Lian, Hui Lu, Shuo Han

“…This study retrospectively analyzed the medical records of culture-negative patients following percutaneous endoscopic surgery to identify risk factors influencing antimicrobial therapy and provide insights for clinical management.MethodsData were retrospectively collected from patients who underwent lumbar percutaneous endoscopic decompression at the Affiliated Hospital of Qingdao University between January 2014 and June 2023. …”
Get full text

Proportion of HIV exposed infants aged 0-6 months that missed nevirapine prophylaxis in Mulago National Referral Hospital, Uganda: a cross-sectional study by Nasambu Hellen, Rujumba Joseph, Mupere Ezekiel, Semitala Fred, Senyonga Ronald, Musoke Philippa

“…While about 95% of HIV positive pregnant and lactating mothers use Antiretroviral therapy in Uganda, a smaller percentage of HIV exposed infants (HEI) receive nevirapine (NVP) prophylaxis. …”
Get full text

Modeling of Shoulder–Elbow Movement with Exponential Parameter Identification During Walking Gaits for Healthy Subjects and Patients with Parkinson’s Disease by Luca Pietrosanti, Giovanni Saggio, Martina Patera, Antonio Suppa, Franco Giannini, Cristiano Maria Verrelli

“…Results: Experiments show that the reconstruction of shoulder and elbow time profiles can be definitely achieved through the proposed procedure with the estimated stiffness parameters turning out to constitute objective and quantitative indices of muscle stiffness (as a pivotal symptom of the pathology), which are able to track changes due to the therapy. Conclusions: The same dynamic model is actually able to capture the main features of the upper limb movement of both (healthy and pathological) walking subjects, with its parameters, in turn, characterizing the nature and progress of the pathology.…”
Get full text

Changes in tear cytokine and lactoferrin levels in postmenopausal women with primary acquired nasolacrimal duct obstruction complicated with obstructed meibomian gland dysfunction by Haili Jin, Xianjie Chen, Feng Ji, Yin Liu, Yonghong Sheng, Guoping Wang, Linfeng Han, Xiaohu Wang, He Ding, Jing Liu, Qingqing Fu

“…Conclusion The level of pro-inflammatory factors in the tears of patients with PANDO complicated with OMGD was significantly increased, which is likely to cause further damage to ocular surface. Anti-inflammatory therapy may help protect ocular surface in postmenopausal women with PANDO.…”
Get full text