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16801
Complementary medicine in orthopaedic and trauma surgery: a cross-sectional survey on usage and needs
Published 2020-09-01“…Most of the patients were admitted due to bone fractures and most underwent operative therapy. Previous or current CAM usage was stated by 76% and 30% of patients, respectively. …”
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16802
Gene-editing in patient and humanized-mice primary muscle stem cells rescues dysferlin expression in dysferlin-deficient muscular dystrophy
Published 2025-01-01“…These findings are the first to show that a CRISPR-mediated therapy can ameliorate dysferlin deficiency. We suggest that gene-edited primary muscle stem cells could exhibit utility, not only in treating dysferlin deficiency syndromes, but also perhaps other forms of muscular dystrophy.…”
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16803
Identification of CβS and ODC antimony resistance markers in anthroponotic cutaneous leishmaniasis field isolates by gene expression profiling
Published 2025-02-01“…Alternative drugs or combination therapy and monitoring drug resistance to prevent the spread of resistant isolates are proper strategies to control the disease.…”
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16804
Recent progress of artificial cells in structure design, functionality and the prospects in food biotechnology
Published 2025-04-01“…These artificial cells demonstrate vast potential for advancements in various biomedical areas, including simulating cell structure and function, creating innovative biosensors, facilitating bioactives transport, enabling micro and nanoreactors, and improving the targeted therapy for chronic foodborne diseases. In the interdisciplinary field of artificial cell construction, based on their constituent components, these systems can be categorized into lipid/polymer vesicles, coacervate, colloidosome, and metal-organic framework (MOF) artificial cells. …”
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16805
Cervical cancer screening utilization among HIV-positive women in Edo State, Nigeria
Published 2024-04-01“…The mean duration of antiretroviral therapy (ART) was 6.72 ± 5.21 years. One hundred ninety-one individuals (51.6%) reported awareness of screening, while 65 (17.6%) had undergone screening. …”
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16806
Long-Term Follow-Up of Patients with 46,XY Partial Gonadal Dysgenesis Reared as Males
Published 2014-01-01“…All had spontaneous puberty; only one needed androgen therapy. Conclusions. There is good prognosis for growth and spontaneous pubertal development but not for fertility. …”
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16807
In silico methods for immunogenicity risk assessment and human homology screening for therapeutic antibodies
Published 2024-12-01“…Although this perspective discusses the in-silico immunogenicity risk assessment for monoclonal antibodies, bi-specifics, multi-specifics, and antibody-drug conjugates, the analysis of additional therapeutic modalities such as enzyme replacement proteins, blood factor proteins, CAR-T, gene therapy products, and peptide drugs is also made available on the ISPRI platform.…”
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16808
The effect of β-carotene supplementation above requirement on the production and reproduction performance of female sheep and goats - A mini review
Published 2024-05-01“…Antioxidant supplementation is proposed as a therapy for encountering resultant stress. In animals, β-carotene functions mainly as pro-vitamin A and as a scavenger of free radicals, especially against singlet-state oxygen. …”
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16809
YTHDF1 Regulates RELA m6A Modification and Activates the NF‐Kappa B Signaling Pathway to Promote the Mechanism of Gastric Cancer
Published 2025-01-01“…ABSTRACT Background Gastric cancer (GC) is an important cause of death. Molecular targeted therapy and immunotherapy are progressing rapidly. …”
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16810
Lipid-Rich Extract from Mexican Avocado Seed (Persea americana var. drymifolia) Reduces Staphylococcus aureus Internalization and Regulates Innate Immune Response in Bovine Mammary...
Published 2019-01-01“…S. aureus internalizes into nonprofessional phagocytes, which allows the evasion of the IIR and turns antimicrobial therapy unsuccessful. An alternative treatment to control this pathogen is the modulation of the innate immune response of the host. …”
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16811
Application of efgartigimod in Chinese patients with myasthenia gravis: a single-center real-world prospective study
Published 2025-01-01“…Efgartigimod could potentially serve as an alternative to long-term corticosteroids therapy.…”
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16812
Haploidentical stem cell transplantation with posttransplant cyclophosphamide in children with Wiskott–Aldrich syndrome: a case report
Published 2025-02-01“…He received immunoglobulin replacement therapy and antimicrobial prophylaxis and underwent HSCT at 4 years 3 months of age. …”
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16813
The value of FDG-PET/CT metabolic parameters and treatment metabolic response in predicting long-term survival of patients with diffuse large B-cell lymphoma
Published 2025-01-01“…All patients have been scheduled for first-line therapy, including the R-CHOP regimen (Rituximab, Cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone). …”
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16814
Characterization of Interleukin-15-Transpresenting Dendritic Cells for Clinical Use
Published 2017-01-01“…Personalized dendritic cell- (DC-) based vaccination has proven to be safe and effective as second-line therapy against various cancer types. In terms of overall survival, there is still room for improvement of DC-based therapies, including the development of more immunostimulatory DC vaccines. …”
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16815
Characterizing the pan-cancer role of exosomal miRNAs in metastasis across cancers
Published 2025-01-01“…Lastly, support vector machine model using exomiR targets gene expression classified responders and non-responders to therapy with an AUROC ranging from 0.72 to 0.96, higher than previously reported gene signatures.…”
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16816
Novel Frostbite Cooling Device for Real-time Assessment and Prevention of Chemotherapy-induced Peripheral Neuropathy
Published 2025-01-01“…These findings highlight the potential advantages of CECS in sustained cooling therapy for CIPN prevention.…”
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16817
Prevention of Cyclophosphamide-Induced Immunosuppression in Mice with the Antimicrobial Peptide Sublancin
Published 2018-01-01“…Taken together, these findings suggest that sublancin plays a crucial role in the protection against immunosuppression in cyclophosphamide-treated mice and could be a potential candidate for use in immune therapy regimens.…”
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