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  1. 16801

    Complementary medicine in orthopaedic and trauma surgery: a cross-sectional survey on usage and needs by Anica Kilper, Alexander Müller, Roman Huber, Niklas Reimers, Ludwig Schütz, Ann-Kathrin Lederer

    Published 2020-09-01
    “…Most of the patients were admitted due to bone fractures and most underwent operative therapy. Previous or current CAM usage was stated by 76% and 30% of patients, respectively. …”
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    Article
  2. 16802

    Gene-editing in patient and humanized-mice primary muscle stem cells rescues dysferlin expression in dysferlin-deficient muscular dystrophy by Helena Escobar, Silvia Di Francescantonio, Julia Smirnova, Robin Graf, Stefanie Müthel, Andreas Marg, Alexej Zhogov, Supriya Krishna, Eric Metzler, Mina Petkova, Oliver Daumke, Ralf Kühn, Simone Spuler

    Published 2025-01-01
    “…These findings are the first to show that a CRISPR-mediated therapy can ameliorate dysferlin deficiency. We suggest that gene-edited primary muscle stem cells could exhibit utility, not only in treating dysferlin deficiency syndromes, but also perhaps other forms of muscular dystrophy.…”
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    Article
  3. 16803

    Identification of CβS and ODC antimony resistance markers in anthroponotic cutaneous leishmaniasis field isolates by gene expression profiling by Farzaneh Zarrinkar, Iraj Sharifi, Razieh Tavakoli Oliaee, Ali Afgar, Elaheh Molaakbari, Mehdi Bamorovat, Zahra Babaei, Ebrahim Eskandari, Ehsan Salarkia, Marzieh Asadi

    Published 2025-02-01
    “…Alternative drugs or combination therapy and monitoring drug resistance to prevent the spread of resistant isolates are proper strategies to control the disease.…”
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    Article
  4. 16804

    Recent progress of artificial cells in structure design, functionality and the prospects in food biotechnology by Li Li, Xiaolin Yao, Guoliang Li, Qianqian Guo, Juan Yue, Wenguang Liu, Yapeng Fang, Adam Midgley, Mouming Zhao, Katsuyoshi Nishinari

    Published 2025-04-01
    “…These artificial cells demonstrate vast potential for advancements in various biomedical areas, including simulating cell structure and function, creating innovative biosensors, facilitating bioactives transport, enabling micro and nanoreactors, and improving the targeted therapy for chronic foodborne diseases. In the interdisciplinary field of artificial cell construction, based on their constituent components, these systems can be categorized into lipid/polymer vesicles, coacervate, colloidosome, and metal-organic framework (MOF) artificial cells. …”
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    Article
  5. 16805

    Cervical cancer screening utilization among HIV-positive women in Edo State, Nigeria by Ngozi R. Osunde, Mercy N. Anayo, Ona Patience, Favour E. Omoregie

    Published 2024-04-01
    “…The mean duration of antiretroviral therapy (ART) was 6.72 ± 5.21 years. One hundred ninety-one individuals (51.6%) reported awareness of screening, while 65 (17.6%) had undergone screening. …”
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  6. 16806

    Long-Term Follow-Up of Patients with 46,XY Partial Gonadal Dysgenesis Reared as Males by Juliana Gabriel Ribeiro de Andrade, Antonia Paula Marques-de-Faria, Helena Campos Fabbri, Maricilda Palandi de Mello, Gil Guerra-Júnior, Andréa Trevas Maciel-Guerra

    Published 2014-01-01
    “…All had spontaneous puberty; only one needed androgen therapy. Conclusions. There is good prognosis for growth and spontaneous pubertal development but not for fertility. …”
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    Article
  7. 16807

    In silico methods for immunogenicity risk assessment and human homology screening for therapeutic antibodies by Aimee E. Mattei, Andres H. Gutierrez, Soorya Seshadri, Jacob Tivin, Matt Ardito, Amy S. Rosenberg, William D. Martin, Anne S. De Groot

    Published 2024-12-01
    “…Although this perspective discusses the in-silico immunogenicity risk assessment for monoclonal antibodies, bi-specifics, multi-specifics, and antibody-drug conjugates, the analysis of additional therapeutic modalities such as enzyme replacement proteins, blood factor proteins, CAR-T, gene therapy products, and peptide drugs is also made available on the ISPRI platform.…”
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    Article
  8. 16808

    The effect of β-carotene supplementation above requirement on the production and reproduction performance of female sheep and goats - A mini review by Osman Ahmed, Abubeker Hassen, Khoboso Lehloenya

    Published 2024-05-01
    “…Antioxidant supplementation is proposed as a therapy for encountering resultant stress. In animals, β-carotene functions mainly as pro-vitamin A and as a scavenger of free radicals, especially against singlet-state oxygen. …”
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    Article
  9. 16809

    YTHDF1 Regulates RELA m6A Modification and Activates the NF‐Kappa B Signaling Pathway to Promote the Mechanism of Gastric Cancer by Yangyuan Huang, Shihao Liang, Liping Li, Qingyu Zeng, Bin Li

    Published 2025-01-01
    “…ABSTRACT Background Gastric cancer (GC) is an important cause of death. Molecular targeted therapy and immunotherapy are progressing rapidly. …”
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    Article
  10. 16810

    Lipid-Rich Extract from Mexican Avocado Seed (Persea americana var. drymifolia) Reduces Staphylococcus aureus Internalization and Regulates Innate Immune Response in Bovine Mammary... by Marisol Báez-Magaña, Alejandra Ochoa-Zarzosa, Nayeli Alva-Murillo, Rafael Salgado-Garciglia, Joel Edmundo López-Meza

    Published 2019-01-01
    “…S. aureus internalizes into nonprofessional phagocytes, which allows the evasion of the IIR and turns antimicrobial therapy unsuccessful. An alternative treatment to control this pathogen is the modulation of the innate immune response of the host. …”
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    Article
  11. 16811

    Application of efgartigimod in Chinese patients with myasthenia gravis: a single-center real-world prospective study by Geke Zhu, Han Zhou, Wanying Wang, Yongbo Ma, Xiangtao Nie, Wenjing Qi, Lei Hao, Xiuming Guo

    Published 2025-01-01
    “…Efgartigimod could potentially serve as an alternative to long-term corticosteroids therapy.…”
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  12. 16812
  13. 16813

    The value of FDG-PET/CT metabolic parameters and treatment metabolic response in predicting long-term survival of patients with diffuse large B-cell lymphoma by Abbas Yousefikoma, Mohamad Mehdi Karimy Taha

    Published 2025-01-01
    “…All patients have been scheduled for first-line therapy, including the R-CHOP regimen (Rituximab, Cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone). …”
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  14. 16814

    Characterization of Interleukin-15-Transpresenting Dendritic Cells for Clinical Use by J. M. J. Van den Bergh, E. L. J. M. Smits, M. Versteven, H. De Reu, Z. N. Berneman, V. F. I. Van Tendeloo, E. Lion

    Published 2017-01-01
    “…Personalized dendritic cell- (DC-) based vaccination has proven to be safe and effective as second-line therapy against various cancer types. In terms of overall survival, there is still room for improvement of DC-based therapies, including the development of more immunostimulatory DC vaccines. …”
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  15. 16815

    Characterizing the pan-cancer role of exosomal miRNAs in metastasis across cancers by Piyush Agrawal, Gulden Olgun, Arashdeep Singh, Vishaka Gopalan, Sridhar Hannenhalli

    Published 2025-01-01
    “…Lastly, support vector machine model using exomiR targets gene expression classified responders and non-responders to therapy with an AUROC ranging from 0.72 to 0.96, higher than previously reported gene signatures.…”
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  16. 16816
  17. 16817

    Prevention of Cyclophosphamide-Induced Immunosuppression in Mice with the Antimicrobial Peptide Sublancin by Shuai Wang, Shuo Huang, Qianhong Ye, Xiangfang Zeng, Haitao Yu, Desheng Qi, Shiyan Qiao

    Published 2018-01-01
    “…Taken together, these findings suggest that sublancin plays a crucial role in the protection against immunosuppression in cyclophosphamide-treated mice and could be a potential candidate for use in immune therapy regimens.…”
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    Article
  18. 16818
  19. 16819
  20. 16820