Tacrolimus for Remission Induction and Maintenance Therapy in Patients with Ulcerative Colitis: A Retrospective Evaluation Study by Ayumi Ito, Bunei Iizuka, Teppei Omori, Shinichi Nakamura, Katsutoshi Tokushige

“…In this retrospective study, we compared the efficacy of tacrolimus (TAC) or prednisolone (PSL) for maintenance therapy in patients with ulcerative colitis (UC) at remission. …”
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Phage Therapy as a Rescue Treatment for Recurrent <i>Pseudomonas aeruginosa</i> Bentall Infection by Victor Eiferman, Pierre-Adrien Vion, Alexandre Bleibtreu

Subjects: “…phage therapy…”
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Intertoe Squamous Cell Carcinoma Developed in a Patient with Rheumatoid Arthritis under Etanercept Therapy by Efstathios Rallis, Vasiliki-Kalliopi Bournia, Constantinos Verros, Alexios Iliopoulos

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Effect of play therapy and storytelling on the anxiety level of hospitalized children: a randomized controlled trial by Fatemeh Abdi, Ali Karamoozian, Mostafa Lotfilou, Fatemeh Gholami, Negin Shaterian, Alireza Abasi Niasar, Ehsan Aghapour, Mohammadamin Jandaghian-Bidgoli

Subjects: “…Play therapy…”
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Impact of Inappropriate Empiric Antimicrobial Therapy on Mortality of Septic Patients with Bacteremia: A Retrospective Study by Saoraya Lueangarun, Amorn Leelarasamee

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Beta Blocker Therapy in Heart Failure Patients with Active Cocaine Use: A Systematic Review by Baldeep K. Mann, Janpreet S. Bhandohal, Mohammad Saeed, Gerald Pekler

“…The use of beta blocker therapy appears to be safe and beneficial in heart failure patients with active cocaine use, although the evidence is not robust. …”
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Innovative Lipid Nanoparticles Co-Delivering Hydroxychloroquine and siRNA for Enhanced Rheumatoid Arthritis Therapy by Yanru Feng, Xintong Pan, Ziqian Li, Yue Li, Ya’nan Sun, Shaokun Yang, Chaoxing He, Yunjie Dang, Lu Huang, Bai Xiang

“…<b>Methods:</b> In this study, we introduce a novel lipid nanoparticle formulation co-delivering hydroxychloroquine (HCQ) and siRNA targeting TNF-α (si<i>TNF-α</i>) using microfluidic technology, marking the first use of such a combination for RA therapy. <b>Results:</b> In LPS-stimulated RAW 264.7 cells, the nanoparticles effectively reduced inflammatory markers. …”
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Duration of Antibiotic Therapy for Critically Ill Patients with Bloodstream Infections: A Retrospective Cohort Study by Thomas C Havey, Robert A Fowler, Ruxandra Pinto, Marion Elligsen, Nick Daneman

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Biomimetic polydopamine loaded with janus kinase inhibitor for synergistic vitiligo therapy via hydrogel microneedles by Chunying Li, Wenwen Wang, Junyi Shao, Sen Zhou, Xiaolin Ji, Youxia Xi, Qiuyang Xu, Yuhan Huang, Jingle Wang, Yilin Wan, Zhiming Li

“…Reducing the accumulation of CD8+ T cells by safeguarding melanocytes and keratinocytes from oxidative stress may be contemplated as a promising approach for vitiligo therapy. Results In this study, we introduce a novel therapeutic agent called PDA-JAKi, which is capable of both eliminating oxidative stress and inhibiting T cell activation. …”
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Mesenchymal stem cells and their extracellular vesicle therapy for neurological disorders: traumatic brain injury and beyond by Aref Yarahmadi, Masoumeh Dorri Giv, Reza Hosseininejad, Azin Rezaie, Narges Mohammadi, Hamed Afkhami, Hamed Afkhami, Hamed Afkhami, Arastoo Farokhi

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The Role of Targeted Focal Therapy in the Management of Low-Risk Prostate Cancer: Update on Current Challenges by Daniel W. Smith, Diliana Stoimenova, Khadijah Eid, Al Barqawi

“…The goals of this paper are to discuss the problems of overdiagnosis and overtreatment since the advent of PSA screening as well as the potential for targeted focal therapy (TFT) to bridge the gap between AS and definitive therapies. …”
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Exosome-loading miR-205: a two-pronged approach to ocular neovascularization therapy by Hui-ying Zhang, Qiu-yang Zhang, Qing Liu, Si-guo Feng, Yan Ma, Feng-sheng Wang, Yue Zhu, Jin Yao, Biao Yan

“…However, some patients exhibit poor responses to current anti-VEGF therapies due to resistance and limited efficacy. Recent studies have highlighted the roles of noncoding RNAs in various biological processes, paving the way for RNA-based therapeutics. …”
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Mesenchymal Stem Cell-Based Therapy of Inflammatory Lung Diseases: Current Understanding and Future Perspectives by C. Randall Harrell, Ruxana Sadikot, Jose Pascual, Crissy Fellabaum, Marina Gazdic Jankovic, Nemanja Jovicic, Valentin Djonov, Nebojsa Arsenijevic, Vladislav Volarevic

“…In addition to the suppression of lung-infiltrated immune cells, MSCs have potential to differentiate into alveolar epithelial cells in vitro and, accordingly, represent new players in cell-based therapy of inflammatory lung disorders. In this review article, we described molecular mechanisms involved in MSC-based therapy of acute and chronic pulmonary diseases and emphasized current knowledge and future perspectives related to the therapeutic application of MSCs in patients suffering from acute respiratory distress syndrome, pneumonia, asthma, chronic obstructive pulmonary diseases, and idiopathic pulmonary fibrosis.…”
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Advancing CNS Therapeutics: Enhancing Neurological Disorders with Nanoparticle-Based Gene and Enzyme Replacement Therapies by Liu S, Li H, Xi S, Zhang Y, Sun T

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Mesenchymal Stem Cell Therapy for Cardiac Inflammation: Immunomodulatory Properties and the Influence of Toll-Like Receptors by F. van den Akker, S. C. A. de Jager, J. P. G. Sluijter

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Design of Semantic Matching Model of Folk Music in Occupational Therapy Based on Audio Emotion Analysis by Wensi Ouyang

“…Occupational Therapy International…”
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Fine Needle Ethanol Injection Therapy for Human Pancreatic Adenocarcinoma Subcutaneously Xenografted in Nude Mice by Pierre C Gagnon, Marguerite Daumas, Norbert Allieres, Paul D Vincensini, Thierry Ponchon, Etienne Hollande

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Superparamagnetic Bifunctional Bisphosphonates Nanoparticles: A Potential MRI Contrast Agent for Osteoporosis Therapy and Diagnostic by Y. Lalatonne, M. Monteil, H. Jouni, J. M. Serfaty, O. Sainte-Catherine, N. Lièvre, S. Kusmia, P. Weinmann, M. Lecouvey, L. Motte

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WNT11 Promotes immune evasion and resistance to Anti-PD-1 therapy in liver metastasis by Weiliang Jiang, Bingjie Guan, Hongcheng Sun, Yushuai Mi, Sanjun Cai, Rong Wan, Xinxiang Li, Peng Lian, Dawei Li, Senlin Zhao

“…Moreover, CAMKII inhibition increases the efficacy of anti-PD-1 therapy in mouse model of LM. Serum expression of WNT11 is identified as a potential minimally invasive biomarker in the management of colorectal cancer-LM with immunotherapy. …”
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Cerebral Phosphorus Magnetic Resonance Spectroscopy in a Patient with Giant Cell Arteritis and Endovascular Therapy by Ruth Steiger, Lisa-Maria Walchhofer, Andreas Rietzler, Katherina J. Mair, Michael Knoflach, Bernhard Glodny, Elke R. Gizewski, Astrid E. Grams

“…In this case study, we report on a patient with stenosis and wall contrast enhancement in the left internal carotid and the right vertebral artery, due to giant cell arteritis. 31P MRS revealed a decreased inorganic phosphate-to-phosphocreatine ratio (Pi/PCr) in regions with a prolonged mean transit time (MTT). After systemic therapy and angioplasty of the right vertebral artery, the stenosis and the symptoms improved and the area of prolonged MTT became smaller. …”
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