Perspectives of Midwives and Nurse Practitioners in Kentucky on Exercise Counseling During Pregnancy: A Qualitative Study by Madhawa Perera, Taniya S. Nagpal, Maire M. Blankenship, Danilo V. Tolusso, Jordyn M. Cox, Dilini Prashadika, Mark Schafer, Rachel A. Tinius

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Exploring the potential effect and mechanisms of protocatechuic acid on human hair follicle melanocytes by Li Bo, Tan Jun, Zou Bosheng, Liu Xiaojia, Yu Yiling

“…This study suggested that PCA has an inhibitory effect on the production of melanin through down-regulation of the expression of melanogenesis-related protein and the effect of anti-oxidation, which could be useful for the therapy of melanin overproduction or skin whitening.…”
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Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation. by Alexandra Schuetz, Claire Deleage, Irini Sereti, Rungsun Rerknimitr, Nittaya Phanuphak, Yuwadee Phuang-Ngern, Jacob D Estes, Netanya G Sandler, Suchada Sukhumvittaya, Mary Marovich, Surat Jongrakthaitae, Siriwat Akapirat, James L K Fletscher, Eugene Kroon, Robin Dewar, Rapee Trichavaroj, Nitiya Chomchey, Daniel C Douek, Robert J O Connell, Viseth Ngauy, Merlin L Robb, Praphan Phanuphak, Nelson L Michael, Jean-Louis Excler, Jerome H Kim, Mark S de Souza, Jintanat Ananworanich, RV254/SEARCH 010 and RV304/SEARCH 013 Study Groups

“…Chronic HIV infection is characterized by mucosal Th17 cell depletion, microbial translocation and subsequent immune-activation, which remain elevated despite antiretroviral therapy (ART) correlating with increased mortality. …”
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Prenatally Diagnosed Cardiac Tumors and Tuberous Sclerosis Complex: A Single-Center Experience by Matija Bakoš, Dora Jelinek, Ana Ćorić Ljoka, Nada Sindičić Dessardo, Dalibor Šarić, Ruža Grizelj

“…Early mTOR inhibitor therapy offers promise in mitigating TSC-related complications and improving outcomes.…”
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Improvement of Blood Plasmalogens and Clinical Symptoms in Parkinson’s Disease by Oral Administration of Ether Phospholipids: A Preliminary Report by Shiro Mawatari, Shinji Ohara, Yoshihide Taniwaki, Yoshio Tsuboi, Toru Maruyama, Takehiko Fujino

“…Nonmotor symptoms in PD include sleep problems, depression, and dementia, which are not adequately controlled with dopaminergic therapy. Here, we report the efficacy of oral administration of scallop-derived ether phospholipids to some nonmotor symptoms of PD. …”
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The mirror preference test: A reverse translational approach to study anomalous subjective experience in rats by Daria Chestnykh, Liubov S. Kalinichenko, Stephan von Hörsten, Johannes Kornhuber, Christian P. Müller

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Serum levels of tumor necrosis factor-alpha and vascular endothelial growth factor as markers of disease activity in patients with axial spondyloarthritis by Mahendran Bhuvanesh, Chilkuri Balaji, Chinnadurai Saranya, Ramamoorthy Ramesh, Trichangode Natesan Tamilselvam, Sankaralingam Rajeswari

“…Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)/Bath Ankylosing Spondylitis Functional Index (BASFI), serum TNF-α, and VEGF levels were assessed at baseline and the same parameters were assessed after 24 weeks of therapy with either etanercept or NSAIDs (20 patients in each group). …”
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Design and synthesis of antiproliferative 2-oxoindolin-3-ylidenes incorporating urea function with potential VEGFR-2 inhibitory properties by Dalia R. Aboshouk, M. Adel Youssef, Siva S. Panda, Benson M. Kariuki, Mohamed S. Bekheit, Ahmed R. Hamed, Walid Fayad, Ahmed A. F. Soliman, Adel S. Girgis

“…Abstract Targeted therapy is preferable over other therapeutics due to its limitation of drawbacks and better pharmaceutical outcomes. …”
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Efficacy of a complex plant-based preparation for poultry mycotoxicosis by E. V. Kuzminova, E. P. Dolgov, M. P. Semenenko, P. V. Miroshnichenko

“…Pharmacological effect of fibralin was demonstrated by improvement of blood morphobiochemical parameters in poultry, i.e. reduction of leukocytes by 19.3% and cholesterol by 13.6%; and an increase in the number of erythrocytes by 19.4%, hemoglobin by 8.1% and calcium by 9.5%. Antitoxin therapy had a positive effect on liver structure and functions and that fact was confirmed by a decrease in aminotransferase level in serum and normal levels of total protein. …”
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Retrospective database analysis on the demographics and resource utilization of patients with Parkinson’s disease in Quebec, Canada by Véronique Baribeau, Shawn Mohammed, Amnah Awan, Diana Parison, Jean Lachaine

“…This study underscores the need for enhanced therapeutic strategies, particularly for patients inadequately controlled with standard therapies.…”
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Retrospective Study Looking at Cinacalcet in the Management of Hyperparathyroidism after Kidney Transplantation by Habib Mawad, Hugues Bouchard, Duy Tran, Denis Ouimet, Jean-Philippe Lafrance, Robert Zoël Bell, Sarah Bezzaoucha, Anne Boucher, Suzon Collette, Vincent Pichette, Lynne Senécal, Michel Vallée

“…Cinacalcet was stopped within the first month in 12 of these patients of which 7 had to restart therapy. The main reason for restarting cinacalcet was hypercalcemia. …”
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Hemorrhagic syndrome at liver cirrhosis by I. A. Kurkina, O. S. Volkova, M. V. Mayevskaya, V. T. Ivashkin

“…Strategy in treatment of hemorrhagic complications in LC is directed on prevention of pending bleedings and well-timed onset of medical actions in the case of its development. Basic principles of therapy are: application of erythrocytes, plasma, platelets concentrate, recombinant factor VIIa, concentrates of prothrombin complex, desmopressin, antifibrinolytic drugs, thrombo-and erythropoietin, antibiotics. …”
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Computational biology assisted exploration of phytochemicals derived natural inhibitors to block BZLF1 gene activation of Epstein–Bar virus in host by Muhammad Naveed, Muzamal Hussain, Tariq Aziz, Nimra Hanif, Nazia Kanwal, Arooj Arshad, Ayaz Ali Khan, Abdulrahman Alshammari, Metab Alharbi

“…Despite the lack of a vaccination, antiviral medications offer some therapy alternatives. The EBV BZLF1 gene significantly impacts viral replication and infection severity. …”
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Effect of epicanthoplasty on the descent of the eyebrow by Yong-Il Shin, Kyoung-Jin Kang, Jae-Ran Hong, Montri Khammoonta, Phoebe Kar Wai Lam, Sang-Yoon Lee

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Meta-Analysis of Atrial Fibrillation Ablation in Patients with Systolic Heart Failure by Mohammed Ruzieh, Andrew J. Foy, Nader M. Aboujamous, Morgan K. Moroi, Gerald V. Naccarelli, Mehrdad Ghahramani, Shaffi Kanjwal, Joseph E. Marine, Khalil Kanjwal

“…To determine if catheter ablation for AF is superior to medical therapy alone in patients with coexisting HF, we conducted this systematic review and meta-analysis. …”
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Determine the Level of IL-17 in People Recovering from Viral Infections of the Respiratory System by Zahraa Khalid Al-Kheroo, Khalid N. Al-Kheroo, Mahmood Abd Al Jabbar Al-Tobje

“…Objective: Numerous illnesses, such as bacterial and viral infections, affect the respiratory system. Since no known therapy for viruses directly influences health, viral infections are typically more deadly than bacterial ones. …”
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Normalization of Cystic Fibrosis Immune System Reverses Intestinal Neutrophilic Inflammation and Significantly Improves the Survival of Cystic Fibrosis MiceSummary by Callie E. Scull, Yawen Hu, Scott Jennings, Guoshun Wang

“…Thus, normalization of the CF immune system may offer a novel therapy to treat CF intestinal disease.…”
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Next generation sequencing uncovers multiple miRNAs associated molecular targets in gallbladder cancer patients by Rahul Saxena, Baskar Chakrapani, M. P. Sarath Krishnan, Amit Gupta, Sweety Gupta, Jayanta Das, Subash C. Gupta, Anissa A. Mirza, Shalinee Rao, Bela Goyal

“…Our research emphasizes the importance of precision medicine, targeting pathways using sense and anti-sense miRNAs as potential therapies in GBC.…”
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Spinal Reflex Recovery after Dorsal Rhizotomy and Repair with Platelet-Rich Plasma (PRP) Gel Combined with Bioengineered Human Embryonic Stem Cells (hESCs) by Mateus Vidigal de Castro, Moníze Valéria Ramos da Silva, Gabriela Bortolança Chiarotto, Maria Helena Andrade Santana, Ângela Cristina Malheiros Luzo, Sergiy Kyrylenko, Alexandre Leite Rodrigues de Oliveira

“…Here, aiming to enhance previous results, cell therapy with bioengineered human embryonic stem cells (hESCs) to overexpress fibroblast growth factor 2 (FGF2) was combined with PRP. …”
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Osteopontin at the Crossroads of Inflammation and Tumor Progression by Luigi Mario Castello, Davide Raineri, Livia Salmi, Nausicaa Clemente, Rosanna Vaschetto, Marco Quaglia, Massimiliano Garzaro, Sergio Gentilli, Paolo Navalesi, Vincenzo Cantaluppi, Umberto Dianzani, Anna Aspesi, Annalisa Chiocchetti

“…Thus, it represents one of the most attracting targets for cancer therapy. Within the tumor mass, OPN is secreted in various forms either by the tumor itself or by stroma cells, and it can exert either pro- or antitumorigenic effects according to the cell type and tumor microenvironment. …”
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