Relation Between Glycated Hemoglobin Level and Hearing Loss in Type 2 Diabetic Patients by Mayada ElSherif, Aya Fathey El Sayed Mahfouz, Noha Mohamed Gaber Amin, Hesham Saad Kozou

“…Background: Glycemic control and the efficacy of therapy in diabetic patients with type 2 diabetes during the previous 2-3 months are usually evaluated by measuring the glycated hemoglobin (HbA1c). …”
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Prosaposin – A plausible biomarker in head and neck squamous cell carcinoma by Avradeep Datta, Rajandeep Kaur, Anshika Chauhan, Geeta Singh Boora, Himanshu Garg, Debajyoti Chatterjee, Jaimanti Bakshi, Sushmita Ghoshal, Arnab Pal

“…Materials and methods: Serum PSAP levels were estimated in biopsy-proven HNSCC cases (n = 98) before and after completion of therapy and compared with age and sex-matched healthy volunteers (n = 44). …”
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Contemporary Management of Patent Foramen Ovale: A Multinational Survey on Cardiologists’ Perspective by Maciej Dębski, Amr Abdelrahman, Halia Alshehri, Marloe Prince, Andrew Wiper, Shajil Chalil, Dariusz Dudek, Christopher J. White, David Hildick-Smith, David H. Roberts

“…A similar pattern was noted in the lack of routine screening for thrombophilia and the use of the long-term single antiplatelet therapy. Conclusions. The study shows a vast spectrum of opinions on the optimal approach to PFO closure with significant differences between the US, UK, and Gulf countries. …”
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Economic Burden of HIV in a Commercially Insured Population in the United States by Cindy Y. Chen, Prina Donga, Alicia K. Campbell, Babafemi Taiwo

“…**Background:** With advances in antiretroviral therapy (ART), people with HIV infection are living longer. …”
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TB prevention activities in the WHO European Region by A. Matteelli, Z. Mkrtchyan, T. Masini, A. Hovhannesyan, G. Kuchukhidze, S. Ahmedov, P. Kerndt, L. Rossi, A. Yedilbayev, D. Falzon, A. Dadu

“…CONCLUSION: The survey identified several important areas that the PASS initiative will focus on to accelerate efforts towards reaching the targets set at the 2027 UN High-Level Meeting on TB for preventive therapy in the European Region. This will require a massive scale-up of efforts and larger investments, as well as coordinated approaches and interventions across the ‘cascade’ of prevention, from the identification of target populations to the completion of treatment.…”
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Application of IgG-Derived Natural Treg Epitopes (IgG Tregitopes) to Antigen-Specific Tolerance Induction in a Murine Model of Type 1 Diabetes by Leslie P. Cousens, Yan Su, Elizabeth McClaine, Xin Li, Frances Terry, Robert Smith, Jinhee Lee, William Martin, David W. Scott, Anne S. De Groot

“…Implementation of these defined regulatory T cell epitopes for therapy of T1D and other autoimmune diseases may lead to a paradigm shift in disease management.…”
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pir-hsa-216911 inhibit pyroptosis in hepatocellular carcinoma by suppressing TLR4 initiated GSDMD activation by Zhouxiang Liao, Lichao Yang, Xiaojing Cheng, Xuejing Huang, Qi Zhang, Daoqiang Wen, Zhenyu Song, Yasi Li, Sha Wen, Yongfeng Li, Meizhen Ou, Zhangnan Huang, Tianqi Liu, Min He

“…These findings have significant implications for HCC molecular subtyping and as a potential target for cancer therapy.…”
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Enhancing gene transfer to renal tubules and podocytes by context-dependent selection of AAV capsids by Taisuke Furusho, Ranjan Das, Hideyuki Hakui, Anusha Sairavi, Kei Adachi, Mia S. Galbraith-Liss, Pratheppa Rajagopal, Masahiro Horikawa, Shuhua Luo, Lena Li, Kentaro Yamada, Nicole Andeen, Gregory A. Dissen, Hiroyuki Nakai

“…Abstract AAV vectors show promise for gene therapy; however, kidney gene transfer remains challenging. …”
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Determinants of tuberculosis treatment failure in public health facilities of Jigjiga Town, Somali Regional State, Ethiopia: A multi-center case-control study by Nasir Tayib Nur, Yadeta Dessie, Samuel Demissie Darcho, Samrawit Berihun, Behailu Hawulte Ayele

“…In the current study, determinants of tuberculosis treatment failure were being male (AOR = 4.06, 95 % CI: 1.65, 9.75), age 30–40 years (AOR = 0.24, 95 % CI: 0.10, 0.54), receiving directly observed therapy treatment (AOR = 3.94, 95 % CI: 1.63, 9.51), adherence to tuberculosis medication (AOR = 7.56, 95 % CI: 2.70, 20.78), being treated at a hospital (AOR = 11.89, 95 % CI: 3.80, 33.79), and being HIV positive (AOR = 4.783, 95 % CI: 1.46, 15.65). …”
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Cytokines and Chemokines as Biomarkers of Community-Acquired Bacterial Infection by Michal Holub, David A. Lawrence, Nancy Andersen, Alžběta Davidová, Ondřej Beran, Vilma Marešová, Pavel Chalupa

“…Furthermore, elevated levels of IL-1Ra, IL-6, and TNF-α decreased within 3 days of antibiotic therapy to levels observed in control subjects. The results show IL-1Ra as a potential useful biomarker of community-acquired bacterial infection.…”
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Curative Effect of AD-MSCs against Cisplatin-Induced Hepatotoxicity in Rats is Potentiated by Azilsartan: Targeting Oxidative Stress, MAPK, and Apoptosis Signaling Pathways by Amany Abdlrehim Bekhit, Olivia N. Beshay, Michael A. Fawzy, Sara Mohamed Naguib Abdel-Hafez, Gaber El-Saber Batiha, Farid S. Ataya, Moustafa Fathy

“…Moreover, treatment with combination therapy (AZIL.L or H + AD-MSCs) considerably mitigated all previously mentioned alterations superior to AZIL or AD-MSCs alone, which might be attributed to the AZIL-enhanced homing ability of AD-MSCs into the injured liver tissue. …”
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Difficult choledocholithiasis – result of overdue surgical treatment of gallstone disease by S. G. Shapovalyants, T. B. Ardasenov, A. G. Pankov, S. A. Budzinsky, V. S. Veselova

“…Part of patients (84) received conservative therapy for biliary colic and complications of GSD, abandoning of operative treatment resulted in, first, development of severe complication – choledocholithiasis, second, development of unfavorable anatomical conditions for its noninvasive resolution.Conclusion. …”
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N-Cadherin Upregulation Promotes the Neurogenic Differentiation of Menstrual Blood-Derived Endometrial Stem Cells by Yanli Liu, Fen Yang, Shengying Liang, Qing Liu, Sulei Fu, Zhenyu Wang, Ciqing Yang, Juntang Lin

“…Peripheral nerve injuries are typically caused by either trauma or medical disorders, and recently, stem cell-based therapies have provided a promising treatment approach. …”
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Combination of potassium oxonate with anti-PD-1 for the treatment of colorectal cancer by Yuanyuan Wang, Chenxi Hu, Tianpeng Du, Jiawen Li, Kaiyuan Hui, Xiaodong Jiang

“…IntroductionIdentification of effective therapies for colorectal cancer (CRC) remains an urgent medical need, especially for the microsatellite stable (MSS) phenotype. …”
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Efektivitas Ifdil perceptual light technique untuk mengurangi social anxiety siswa obesitas by Iqbal Arrahman, Ifdil Ifdil, Yeni Karneli, Rima Pratiwi Fadli, Annisaislami Khairati

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A Case Report of Aicardi-Goutières Syndrome Type 7 Caused by IFIH1 Gene Mutation and a Literature Review by ZHAO Min, SHU Zhou, HAN Tongxin, FU Yanhua, GAO Tianji, MAO Huawei

“…The first brain MRI showed no lesions.Rehabilitation therapy in the past several years has shown no improvement.Recent brain CT revealed multiple intracranial calcifications. …”
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How integrated knowledge translation worked to reduce federal policy barriers to the implementation of medication abortion in Canada: a realist evaluation by Sarah Munro, Kate Wahl, Sheila Dunn, Courtney Devane, Linda C. Li, Wendy V. Norman

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Multimodal treatments and the risk of breast cancer-related lymphedema: insights from a nationally representative cohort in South Korea by Sung Hoon Jeong, Seong Min Chun, Miji Kim, Ye Seol Lee, Jisun Kim, Ja-Ho Leigh, Yoon-Hee Choi

“…Abstract Background As the roles of chemotherapy (Chemo) and radiation therapy (Radio) in the definitive treatment of breast cancer have expanded, a broader understanding of the factors associated with breast cancer-related lymphedema (BCRL) has become increasingly essential. …”
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The efficacy of acupuncture in relieving postoperative pain in patients with low simple anal fistula: Protocol of a prospective, randomised, controlled trial. by Min Yang, De Zheng, Xingtao Jin, Huili Tang, Weiwei Cao, Qianqian Ye, Yin Qu, Zubing Mei

“…Ultimately, the findings of this trial have the potential to offer valuable insights into the utility of acupuncture as an adjunctive therapy for postoperative pain management among anal fistula patients, thereby informing future clinical practice and research directions.…”
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Technologically-Treated Polyclonal Affinity-Purified Antibodies to the Tumor Necrosis Factor-α, Brain Specific S-100 Protein and Histamine in Treatment of Functional Dyspepsia: Res... by Yu. O. Shulpekova, I. V. Maev, V. B. Grinevich, I. B. Khlynov, Yu. G. Shvarts, V. T. Ivashkin

“…None of the patients in Kolofort® group had progression of FD symptoms or required additional therapy. There were 29 adverse events (AEs) recorded in 25 patients including 16 cases in 13 (8.6 %) patients in Kolofort® group and 13 AEs in 12 (7.6 %) patients in placebo group.Conclusion: the clinical trial demonstrates the positive effect of Kolofort® in FD with a favorable safety profile.…”
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