The Analysis of Correlative Factors of Visual Acuity with Intravitreal Conbercept Injection in Macular Edema Associated with Branch Retinal Vein Occlusion by Wenjuan Luo, Fengjiao Jia, Min Liu, Yunxiao Wang, Ting Zhang

“…The PLT in months 1, 3, and 6 after therapy has significant improvement of 11.14 μm, 13.03 μm, and 13.49 μm (F=64.116, P<0.01), while the ONLT has a significant decrease of 225.29 μm, 237.66 μm, and 239.11 μm, respectively (F=145.231, P<0.01). …”
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Eliminating Postoperative Nausea and Vomiting in Outpatient Surgery with Multimodal Strategies including Low Doses of Nonsedating, Off-Patent Antiemetics: Is “Zero Tolerance“ Achie... by Susan J. Skledar, Brian A. Williams, Manuel C. Vallejo, Patricia L. Dalby, Jonathan H. Waters, Ronald Glick, Michael L. Kentor

“…., now off-patent) is added. Rescue therapy consists of avoiding unnecessary repeat doses of drugs acting by the same mechanism: haloperidol 2 mg i.v. …”
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Evaluating the Accuracy, Quality, and Readability of Online Breast Cancer Information by Elsie A. Valencia, BS, Chandler S. Cortina, MD, MS, FSSO, FACS, Adrienne N. Cobb, MD, MS, Lubna N. Chaudhary, MD, MS, Tracy Kelly, MD, Amanda L. Kong, MD, MS, FSSO, FACS

“…A qualitative analysis on 50 websites was conducted; the first 10 eligible websites for the following search terms were included: “breast cancer,” “breast surgery,” “breast reconstructive surgery,” “breast chemotherapy,” and “breast radiation therapy.” Websites were required to be in English and not intended for healthcare professionals. …”
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Computational structure-based design of antiviral peptides as potential protein–protein interaction inhibitors of rabies virus phosphoprotein and human LC8 by Saman Rahmati, Fatemeh Zandi, Khadijeh Ahmadi, Ahmad Adeli, Niloofar Rastegarpanah, Massoud Amanlou, Behrouz Vaziri

“…Finally, Pep2 can be used as a potential candidate for peptide-based antiviral therapy against RABV. The identified small peptides may prevent RABV infection based on the results of the current investigation. …”
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Designing Microfluidic Devices to Sort Haematopoietic Stem Cells Based on Their Mechanical Properties by Mingming Du, Dean Kavanagh, Zhibing Zhang, Neena Kalia

“…Such devices may benefit cellular therapy.…”
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Transplacental Transfer of Primaquine and Neurobehavioral Development of Prenatally Exposed Rats by Klaus M. Becker, Lorenna Rosa, Manoella S. B. Fernandes, Rosangela R. de Carvalho, Ana Cecilia X. De-Oliveira, Davyson L. Moreira, Francisco J. R. Paumgartten

“…PQ given in pregnancy, at doses greater than those recommended for malaria therapy, may affect pup postnatal survival and emotional behavior.…”
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Co-Designing a Digital Brief Intervention to Reduce the Risk of Prescription Opioid–Related Harm Among People With Chronic Noncancer Pain: Qualitative Analysis of Patient Lived Exp... by Rachel A Elphinston, Sue Pager, Kelly Brown, Michele Sterling, Farhad Fatehi, Paul Gray, Linda Hipper, Lauren Cahill, Jason P. Connor

“…ObjectiveThis study involved the first phase of co-designing a digital brief intervention to reduce the risk of opioid-related harm by investigating the lived experience of chronic noncancer pain (CNCP) in treatment-seeking patients, with a particular focus on opioid therapy experiences. MethodsEligible patients were those aged between 18 and 70 years with CNCP at a clinically significant level of intensity (a score of ≥4 of 10). …”
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Mandibular (Gnathic) osteosarcoma: Narrative review emphasizing clinical, radiological, and histopathological correlation by Praveen K. Sharma, Iffath Misbah, J.H.Shazia Fathima, Ajay Lucas Rubben, Jeban Chella Bruce

“…Improvements in adjuvant therapies and surgical procedures have improved the results of treatment. …”
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Knockdown of Fibromodulin Inhibits Proliferation and Migration of RPE Cell via the VEGFR2-AKT Pathway by He Hu, Shanshan Li, Jianqiao Li, Chao Huang, Fang Zhou, Li Zhao, Wenzhen Yu, Xiao Qin

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Microvascular disease and heart failure with reduced and preserved ejection fraction in type 2 diabetes by Ify R. Mordi, Aaron Tee, Colin N. Palmer, Rory J. McCrimmon, Alexander S.F. Doney, Chim C. Lang

“…Patients with MiVD could benefit from screening for HF and individualized therapy with treatments that lower HF risk.…”
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Carbidopa/levodopa dose elevation and safety concerns in Parkinson's patients: a cross-sectional and cohort design by Michael S Okun, Peter Schmidt, David W Brodell, Nicole T Stanford, Charles E Jacobson

“…Objective Sinemet, a combination drug containing carbidopa and levodopa is considered the gold standard therapy for the treatment of Parkinson's disease (PD). …”
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Root growth and arbuscular mycorrhizal fungi on woody plants for vegetative stabilization of tropical slopes by I.G. Tejakusuma, E.H. Sittadewi, T. Handayani, T. Hernaningsih, W. Wisyanto, A. Rifai

“…In both sites, neither therapy showed a meaningful change.CONCLUSION: G. arborea has the maximum phosphorus absorption (80%) and biomass weight (660 grams) with M3 dosage in Citatah and 71 percent with 330 g at the same dose in Jati Radio, which is associated with the ideal amount of arbuscular mycorrhizal fungus inoculation. …”
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Novel Antibiotic Combinations of Diverse Subclasses for Effective Suppression of Extensively Drug-Resistant Methicillin-Resistant Staphylococcus aureus (MRSA) by Shumyila Nasir, Muhammad Sufyan Vohra, Danish Gul, Umm E Swaiba, Maira Aleem, Khalid Mehmood, Saadia Andleeb

“…Antibiotic combination therapy with existing antimicrobial agents may provide an immediate treatment option. …”
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End-Of-Life Care for Persons with Advanced Chronic Obstructive Pulmonary Disease: Report of a National Interdisciplinary Consensus Meeting by DM Goodridge, DD Marciniuk, D Brooks, A van Dam, S Hutchinson, P Bailey, S Baxter, P Dorasamy, S Dumont, S Hassan, P Hernandez, A Kerigan, G Rocker, D Wilson, J Young

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Effectiveness and safety of oral vancomycin for the treatment of inflammatory bowel disease associated with primary sclerosing cholangitis: a systematic review and pooled analysis by Wassel Sannaa, Mazen Almasry, Mustafa Peedikayil, Alyssa A. Grimshaw, Mashary Attamimi, Abdulelah AlMutairdi, Badr Al-Bawardy

“…Background: Inflammatory bowel disease (IBD) occurs in up to 70%–80% of patients with primary sclerosing cholangitis (PSC). Oral vancomycin therapy (OVT) has been reported to be effective in the treatment of IBD associated with PSC (IBD-PSC). …”
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Effect of a virtual walking and exercise-based intervention on muscle strength and activation in people with incomplete spinal cord injury by Sara Mollà-Casanova, Elena Muñoz-Gómez, Noemí Moreno-Segura, Marta Inglés, Marta Aguilar-Rodríguez, Núria Sempere-Rubio, Pilar Serra-Añó

“…Abstract This study aims to assess the effect of combining virtual walking (VW) therapy with a physical exercise (PE) program compared to PE alone on lower limb strength and muscle activation in people with incomplete spinal cord injury (iSCI). 38 participants performed 3 sessions/week during 6 weeks of Experimental Intervention (EI): VW and PE; or Control intervention (CI): Placebo-VW and PE. …”
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Bias-corrected serum creatinine from UK Biobank electronic medical records generates an important data resource for kidney function trajectories by Mathias Gorski, Simon Wiegrebe, Ralph Burkhardt, Merle Behr, Helmut Küchenhoff, Klaus J. Stark, Carsten A. Böger, Iris M. Heid

“…This included 206,063 individuals with ≥ 2 assessments over up to 60.2 years (median 6.00 assessments, median time = 8.7 years), where we also obtained eMR-based information on kidney disease or renal replacement therapy. We found an annual eGFR decline of 0.11 (95%-CI = 0.10–0.12) versus 1.04 mL/min/1.73m2/year (95%-CI = 1.03–1.05) without and with bias-correction, the latter being in line with literature. …”
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The efficacy and safety of indobufen in patients with ischemic cardiovascular or cerebrovascular diseases: systematic review and meta-analysis by Xiaolu Luo, Chenglu Lai, Tielong Chen

“…Currently, indobufen is widely used in secondary cardiovascular and cerebrovascular prevention and provides some guidance for antiplatelet therapy in patients with gastrointestinal discomfort or bleeding risk. …”
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Is otologic surgery contributing to the opioid epidemic? by Valerie Dahm, Justin T. Lui, Rudolfs Liepins, Joseph M. Chen, Trung N. Le, Christoph Arnoldner, Vincent Y. W. Lin

“…Otologists gave an estimate how confident they were that their therapy and prescriptions provide sufficient pain control to their patients. …”
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Changes in Serum Cytokines May Predict Therapeutic Efficacy of Tofacitinib in Rheumatoid Arthritis by Yuxuan Li, Lin Yuan, Jie Yang, Yue Lei, Hui Zhang, Liping Xia, Hui Shen, Jing Lu

“…Tofacitinib is a novel therapy for rheumatoid arthritis (RA). The aim of this study was to measure various serum cytokines levels and to explore potential markers predictive of therapeutic efficacy of tofacitinib for RA patients. …”
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