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15541
Acute Liver Failure Caused by Amanita phalloides Poisoning
Published 2012-01-01“…The management of amatoxin poisoning consists of preliminary medical care, supportive measures, detoxification therapies, and orthotopic liver transplantation. The clinical efficacy of any modality of treatment is difficult to demonstrate since randomized, controlled clinical trials have not been reported. …”
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15542
Differences in In Vitro Disintegration Time among Canadian Brand and Generic Bisphosphonates
Published 2014-01-01“…The significantly faster disintegration of the generic tablets as compared to the brand bisphosphonates may have concerning safety and effectiveness implications for patients administering these therapies.…”
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15543
Adipokines regulate the development and progression of MASLD through organellar oxidative stress
Published 2025-02-01“…A comprehensive understanding of the pathogenesis of MASLD/MASH is instrumental for identifying therapies for MASH.…”
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15544
Impact of Periodontitis and Oral Dysbiosis Metabolites in the Modulation of Accelerating Ageing and Human Senescence
Published 2025-01-01“…In this regard, over the local periodontal treatment, lifestyle modifications and adjunctive therapies may offer synergistic benefits in ameliorating both oral and systemic health in ageing populations. …”
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15545
The Case for Musical Instrument Training in Cerebral Palsy for Neurorehabilitation
Published 2016-01-01“…These multiple demands during instrument playing, together with the entertaining character of music, have led to the development and investigation of music-supported therapies, especially for rehabilitation with motor disorders resulting from brain damage. …”
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15546
Interferon-based agents for current and future viral respiratory infections: A scoping literature review of human studies.
Published 2022-01-01“…Studies demonstrated mixed efficacy but generally positive safety and tolerability. Host-directed therapies, such as IFN or IFN inducers, are worthy of additional research to target viral respiratory infections lacking direct-acting antivirals.…”
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15547
Injectable iodine-containing peptide hydrogel for treatment of MRSA infection
Published 2025-05-01“…Our findings highlight the potential of this innovative hydrogel system for stable iodine application under humid and aqueous physiological conditions, offering a promising platform for future antibacterial therapies in clinical settings.…”
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15548
Ignoring Gender-Based Immunometabolic Reprograming, a Risky Business in Immune-Based Precision Medicine
Published 2025-01-01“…On the other hand, reproductive-age females also show a more potent immune response against infections and vaccines than their age-matched males—furthermore, some immune-based therapies, including immune checkpoint inhibitors (ICIs), show gender-based efficacy and adverse events. …”
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15549
Trophic Factors from Tissue Stem Cells for Renal Regeneration
Published 2015-01-01“…Stem cell therapies against renal injury have been advancing. …”
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15550
Muscle-Specific Tyrosine Kinase-Associated Myasthenia Gravis: A Neuromuscular Surprise
Published 2021-01-01“…It responds inconsistently to steroids, but plasma exchange and immunosuppressive therapies have shown promising results. We report a case of a 49-year-old female who presented with acute hypoxic respiratory failure. …”
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15551
Association between HMGB1 and COPD: A Systematic Review
Published 2015-01-01“…Current anti-inflammatory therapies are poorly effective in maintaining lung function and symptoms of COPD. …”
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15552
Inactivation of Zika Virus with Hydroxypropyl-Beta-Cyclodextrin
Published 2025-01-01“…To date, there are no available FDA-approved therapies or vaccines for the specific treatment or prevention of ZIKV infection. …”
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15553
The potential of Dayak tribal herbal leaves as an anti-breast cancer agent: In silico approach
Published 2025-01-01“…Breast cancer is one of the leading causes of mortality among women worldwide, prompting the exploration of alternative, natural therapies. This study examines the anti-breast cancer potential of traditional herbal plants used by the Dayak tribe, particularly Kleinhovia hospita Linn. …”
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15554
Guidance Cue Netrin-1 and the Regulation of Inflammation in Acute and Chronic Kidney Disease
Published 2014-01-01“…Despite improved understanding, there are no effective therapies available to treat AKI. A large body of evidence strongly suggests that ischemia reperfusion injury is an inflammatory disease mediated by both adaptive and innate immune systems. …”
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15555
Systems immunology integrates the complex endotypes of recessive dystrophic epidermolysis bullosa
Published 2025-01-01“…By characterising the phenotype-endotype association in RDEB adults, our study lays the groundwork for translational interventions that could by lessening inflammation, alleviate the everlasting suffering of RDEB patients, while awaiting curative genetic therapies.…”
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15556
Biochemistry of Bacterial Biofilm: Insights into Antibiotic Resistance Mechanisms and Therapeutic Intervention
Published 2025-01-01“…The exploration of combination therapies, involving antimicrobial agents, biofilm-disrupting enzymes, and immunomodulators, is emphasized to enhance the efficacy of existing treatments and overcome biofilm resilience.…”
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15557
Design of a Reconfigurable Robotic System for Flexoextension Fitted to Hand Fingers Size
Published 2016-01-01“…Due to the growing demand for assistance in rehabilitation therapies for hand movements, a robotic system is proposed to mobilize the hand fingers in flexion and extension exercises. …”
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15558
Liposomal Antioxidants for Protection against Oxidant-Induced Damage
Published 2011-01-01“…Antioxidants have yet to be rendered into reliable and safe therapies because of their poor solubility, inability to cross membrane barriers, extensive first-pass metabolism, and rapid clearance from cells. …”
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15559
Applications of Amniotic Membrane and Fluid in Stem Cell Biology and Regenerative Medicine
Published 2012-01-01“…Much progress has been made since the discovery of AM and AF cells with stem cell characteristics nearly a decade ago, but there remain a number of problematic issues stemming from the inherent heterogeneity of these cells as well as inconsistencies in isolation and culturing methods which must be addressed to advance the field towards the development of cell-based therapies. Here, we provide an overview of the recent progress and future perspectives in the use of AM- and AF-derived cells for therapeutic applications.…”
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15560
A Series of 35 Cutaneous Infections Caused by Mycobacterium marinum in Han Chinese Population
Published 2023-01-01“…The aim of this study was to evaluate the differences in time to treatment among patients with different types of skin lesions and who were treated with single or multidrug therapies. In addition, the clinical characteristics of M. marinum infection were explored and the mechanism of the host immune responses was investigated. …”
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