Differentiation therapy targeting the stalled epigenetic developmental programs in pediatric high-grade gliomas by Wang Xiang, Xiaolin Zhang, Minhai Dong, Lijun Wan, Bin Zhang, Feng Wan

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Natural products targeting AMPK signaling pathway therapy, diabetes mellitus and its complications by Min Li, Lu Ding, Lu Ding, Liyan Cao, Zepeng Zhang, Xueyan Li, Zirui Li, Qinjing Xia, Kai Yin, Siyu Song, Zihan Wang, Haijian Du, Daqing Zhao, Xiangyan Li, Zeyu Wang, Zeyu Wang

“…This review article explores the advances in research on natural products that target the AMPK signaling pathway, aiming to inform the development of innovative antidiabetic therapies.…”
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An integrated cellular and sub-cellular model of cancer chemotherapy and therapies that target cell survival by Alexis B. Cook, Daniel R. Ziazadeh, Jianfeng Lu, Trachette L. Jackson

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Patients’ Educational Program Could Improve Azathioprine Adherence in Crohn’s Disease Maintenance Therapy by Lei Wang, Rong Fan, Chen Zhang, Liwen Hong, Tianyu Zhang, Zhengting Wang, Jie Zhong

“…To determine the risk factors of nonadherence to azathioprine (AZA) maintenance therapy for Crohn’s disease (CD) and to evaluate the influence of patients’ educational program on adherence to AZA maintenance therapy. …”
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Electroconvulsive Therapy in a Renal Transplantation Patient: A Rare Combination of Disease and Treatment by Giovanni Malaty, Kerilyn Godbe, Mehdi Elmouchtari, Gurjot Malhi, Justin White, Azziza Bankole, Tracey Criss

“…The safety and efficacy of electroconvulsive therapy (ECT) for the treatment of psychiatric disorders have been demonstrated in a wide variety of patients, including postoperative patients and those who are pregnant. …”
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Does the Level of Confidence Exhibited by Dental Students Predict the Outcome of Complete Denture Therapy? by Indika P. Thilakumara, Kaumudi U. Prathibhani, Sumudu G. K. Rasnayaka, Sachith P. Abeysundara, Rasika M. Jayasinghe

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Bringing MDMA-assisted therapy for PTSD to traditional healthcare systems: tending to set and setting by Dimitri Perivoliotis, Dimitri Perivoliotis, Kayla Knopp, Kayla Knopp, Shannon Remick, Allie Kaigle, Allie Kaigle, Christopher S. Stauffer, Christopher S. Stauffer, Chandra Khalifian, Chandra Khalifian, Tamara R. Wachsman, Bettye E. Chargin, Andrew W. Bismark, Andrew W. Bismark, Al Alam, Al Alam, Leslie Morland, Leslie Morland, Leslie Morland

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Modulation of gut microbiota in targeted cancer therapy: insights on the EGFR/VEGF/KRAS pathways by Li Gong, Shixue Yang, Junli Huang, Yongsheng Li

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ClpB chaperone as a promising target for antimicrobial therapy: A narrative review by Sachini J. Udari, Sayoka Shamodhi, Rumesh M. Nelumdeniya, Udayana Ranatunga, Nimesha N. Senadeera, Chathuranga B. Ranaweera

“…Given its absence in human cells and its essential role in bacterial survival under stress, ClpB is a promising target for antimicrobial therapy. Targeting Hsp100 family proteins could lead to the development of novel antifungal and antiprotozoal treatments. …”
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Narcolepsy treatment: from exorcism and bloodletting to modern therapy with histamine receptor inverse agonists by E. Sakalauskaitė-Juodeikienė, R. Masaitienė

“…In this article, we also review future perspectives for narcolepsy treatment including novel versions of sodium oxybate, the noradrenaline reuptake inhibitor reboxetine, the combination of modafinil and the astroglial connexins inhibitor flecainide, selective hypocretin-2 receptor agonists, and immune-based therapies. …”
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Combination treatment with photodynamic therapy and antibiotic in refractory cutaneous nocardiosis: A case report by Xiaohan Liu, Yang Tan, Qionghui Cheng, Liang Wang, Jinyi Chen, Hong Liu, Wen Ding, Xia Lei

Subjects: “…Photodynamic Therapy…”
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Disability and quality of life in patients with treatment-resistant schizophrenia on long- term clozapine therapy by Dhandapani Nandakumar, Ragul Ganesh, Koushik S. Deb, Raka Jain, Mamta Sood

“…Objectives: To assess disability and quality of life (QOL) in treatment resistant schizophrenia (TRS) on long term clozapine therapy and assess their correlation with positive, negative and cognitive symptoms. …”
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Efficacy of medical thoracoscopy combined with fibrinolytic therapy in the treatment of complicated parapneumonic effusions and empyema by Feng-Fu Zhan, Mao-Hong Huang, Yan-Ping Du, Yan Chen, Han-Han Chen, Yi-Li Lin, Yi-Yuan Chen, Ling Cai, Xiao-Bin Zhang

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Failure of Ketoprofen and Interferon Combination Therapy to Improve Interferon-Resistant Chronic Hepatitis C by Frank H Anderson, Lecheng Zeng, Eric M Yoshida, Natalie R Rock

“…No patient normalized serum aminotransferases after combination therapy. There were no significant differences in mean serum ALT and AST levels before and after ketoprofen intervention. …”
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Thyroid Dysfunction following Radiotherapy and Combined Therapy in Non-Thyroid Head and Neck Cancers by Rais Ahmad Bhat, Om Prakash, Shabab Lalit Angurana

“…The purpose of this study was to evaluate thyroid function following radiotherapy and combined therapy in non-thyroid head and neck cancers. MATERIALS AND METHODS:  It was a prospective study of 51 patients with head and neck cancers for duration of one year. …”
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Ensuring patient access to gene therapies for rare diseases: Navigating reimbursement and coverage challenges by Diane Berry, Carolyn Hickey, Lisa Kahlman, James Long, Christina Markus, Caitlin K. McCombs

“…Molecular Therapy: Methods & Clinical Development…”
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Pharmacological and Pharmacodynamic Implications of Nonsteroidal Anti-Inflammatory Drug Therapy in Elderly Arthritic Patients by W Watson Buchanan

“…There is growing evidence chat elderly patients may be more likely to develop adverse drug reactions to nonsteroidal anti-inflammatory drug/analgesic therapy. This may be due to the physiological changes which accompany ageing as well as multiple drug therapies commonly used in the elderly. …”
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Human Urine-Derived Stem Cells: Potential for Cell-Based Therapy of Cartilage Defects by Long Chen, Lang Li, Fei Xing, Jing Peng, Kun Peng, Yuanzheng Wang, Zhou Xiang

“…Stem cell therapy is considered an optimistic approach to replace current treatments for cartilage defects. …”
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H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy by Monika Podhorecka, Andrzej Skladanowski, Przemyslaw Bozko

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Successful Therapy of Refractory Erythema Nodosum Associated with Crohn's Disease Using Potassium Iodide by John K Marshall, E Jan Irvine

“…While the mechanism of action of this agent is poorly understood, it appears to be an effective and nontoxic therapy for Crohn's-related erythema nodosum and warrants further evaluation in a placebo controlled trial.…”
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