Sympathetic Renal Innervation and Resistant Hypertension by Vito M. Campese, Elaine Ku, Jeanie Park

“…Hypertension in chronic renal disease and renovascular disease is often resistant to therapy. Understanding the pathogenic mechanisms responsible for hypertension in these conditions may lead to improved and more targeted therapeutic interventions. …”
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Contemporary Evaluation and Management of the Diabetic Foot by Bauer E. Sumpio

“…These wounds can frequently benefit from various adjuvants, such as aggressive debridement, growth factors, bioactive skin equivalents, and negative pressure wound therapy. While these, increasingly expensive, therapies have shown promising results in clinical trials, the results have yet to be translated into widespread clinical practice leaving a huge scope for further research in this field.…”
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Prospective Five-Year Follow-Up of Patients with Schizophrenia Suspected with Parkinson’s Disease by Asako Yoritaka, Tetsuo Hayashi, Keiko Fusegi, Rie Inami, Nobutaka Hattori

“…Some patients with schizophrenia and parkinsonism benefit from dopaminergic therapy. Some of these patients may also exhibit Lewy pathology.…”
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Skeletal Cryptococcosis: Case Report and Review of the Literature by Lori Wood, Lil Miedzinski

“…The new azoles may have a role in future therapy.…”
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Postdural Puncture Superior Sagittal Sinus Thrombosis in a Juvenile Case of Clinically Isolated Syndrome by Miriam Michel, Edda Haberlandt, Matthias Baumann, Andreas Entenmann, Michaela Wagner, Kevin Rostasy

“…We report the case of a CVT following lumbar puncture and intravenous glucocorticosteroid therapy in a female adolescent with a clinically isolated syndrome and risk factors for thrombosis. …”
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Strategies to Overcome Antileishmanial Drugs Unresponsiveness by Shyam Sundar, Anup Singh, Om Prakash Singh

“…In the current review, we highlight various steps which could be implemented to halt the increasing unresponsiveness of drugs such as monitoring of therapy in the form of rational dosing and duration of treatment, understanding the mechanism of action of the drugs and drug resistance, identification of markers of resistance, distribution of drugs free of cost, evolution of effective combination therapy and immunotherapy, and proper management of HIV/VL coinfection and post-kala-azar dermal leishmaniasis (PKDL). …”
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Effect of Exercise Rehabilitation Training on Humoral Factors in Patients with Chronic Heart Failure and its Effect Observation by Yi DING, Chenchen GUO, Jinglong SUN, Wanhong WANG, Wangjun HOU, He ZHUANG

“…The control group received routine drug therapy; the combination group received exercise rehabilitation training in addition of the control group treatment. …”
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Everolimus in Heart Transplantation: An Update by Stephan W. Hirt, Christoph Bara, Markus J. Barten, Tobias Deuse, Andreas O. Doesch, Ingo Kaczmarek, Uwe Schulz, Jörg Stypmann, Assad Haneya, Hans B. Lehmkuhl

“…Immediate and adequate reduction of CNI exposure is mandatory from the start of everolimus therapy.…”
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Introducing the Index of Response to Stimulation (IRES): A Novel Metric for Assessing Vagus Nerve Stimulation Outcomes in Drug-Resistant Epilepsy by Flavius-Iuliu Urian, Corneliu Toader, Razvan-Adrian Covache Busuioc, Antonio-Daniel Corlatescu, Horia Petre Costin, Gabriel Iacob, Alexadru Vlad Ciurea

“…<i>Materials and Methods</i>: This retrospective study followed 76 patients aged 20–65, assessing changes in their IRES scores after VNS therapy using the ASPIRE SR 106 device. Therapy settings were adjusted biweekly to optimize efficacy and patient tolerance. …”
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Comparison of clinical and pharmacodynamic features of proton pump inhibitors efficacy in gastroesophageal reflux disease by O. A. Storonova, A. S. Trukhmanov

“…Functional state of stomach mucosa and efficacy of antisecretory therapy was estimated by 24-hour pH or рН-impedance measurement. …”
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Clinical efficacy of cytoreductive radical prostatectomy in the treatment of oligometastatic hormone-sensitive prostate cancer by Feng Qi, Yihang Xu, Zicheng Xu, Qing Zou

“…The proportions of patients with Tx stage (P = 0.027) and Nx stage (P = 0.027) in the no local therapy group were significantly higher than that in the cytoreductive group. …”
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Modified CD15/CD16-CLL1 inhibitory CAR-T cells for mitigating granulocytopenia toxicities in the treatment of acute myeloid leukemia by Rui Zhang, Yifan Zhao, Xiao Chai, Yingshuai Wang, Mohan Zhao, Shujing Guo, Yu Zhang, Mingfeng Zhao

“…CLL1 Chimeric antigen receptor T-cell (CAR-T) therapy, as a promising immunotherapeutic approach, has demonstrated its potential to enhance the prognosis of patients diagnosed with acute myeloid leukemia (AML). …”
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Polyphenols synergistic drugs to ameliorate non-alcoholic fatty liver disease via signal pathway and gut microbiota: A review by Hongcai Li, Jingjing Liang, Mengzhen Han, Zhenpeng Gao

“…Background: Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease with an increasing incidence worldwide. Single drug therapy may have toxic side effects and disrupt gut microbiota balance. …”
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Evaluation of Five Ready-to-Use Bases for the Topical Administration of Propranolol Hydrochloride to Treat Infantile Hemangioma by Chiara Lacassia, Annalisa Cutrignelli, Flavia Maria la Forgia, Sergio Fontana, Antonio Lopalco, Nunzio Denora, Angela Assunta Lopedota

“…This therapy is not necessarily applicable to all patients. …”
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Incidence and risk factors of Vancomycin-induced thrombocytopenia: a six-year real-world study by Yuanchao Zhu, Lishuang Huang, Jingjing Zhang, Liang Liang, Pengfei Jin

“…Multivariate analysis indicated that risk factors for VIT were qSOFA score ≥ 2, underlying renal diseases, duration of vancomycin therapy ≥ 8 days, PLT ≤ 150 × 109/L, and BUN ≥ 12 mmol/L. …”
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Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency by V. S. Scherbakha, O. Z. Okhlobystina, A. V. Korolev, O. S. Shifrin, A. V. Stepanov, A. S. Tertychny, A. V. Okhlobystin, V. T. Ivashkin

“…Nonetheless good therapeutic response was achieved at combined anti-cytokine therapy with immunosuppressive drugs and adequate nutritional support. …”
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Immunotherapy as a neoadjuvant preoperative treatment for locally advanced pulmonary sarcomatoid carcinoma: a case report of clinical efficacy by Hanhan Li, Hanhan Li, Ruilian Chen, Wei Guo, Shang Xiang, Shang Xiang, Jiayang Huang, Jiayang Huang, Hanrui Chen

“…After undergoing eight cycles of neoadjuvant therapy, the opportunity for surgery arose. Postoperative pathology confirmed that the neoadjuvant chemotherapy in this regimen achieved pathological complete remission (pCR). …”
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Does welfare technology contribute to security, activity, participation and independence within municipal elder care? A qualitative study protocol by Ingrid Hellström, Johannes Österholm, Åsa Larsson Ranada, Katarina Baudin, Vedrana B Baric

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Azathioprine Hypersensitivity Syndrome during Treatment of Severe Interstitial Lung Disease with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis by Eri Nakano, Tomohiko Asakawa, Mea Asou, Eri Nohara, Tomoyuki Seki, Makoto Araki

“…Prednisolone plus azathioprine was administered as maintenance therapy. Three exacerbations of the inflammatory response occurred during the subsequent 3 months. …”
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Assessing the possibility of using portable and stationary non-mydriatic fundus cameras for diabetic retinopathy screening assisted by an artificial intelligence-based software pla... by A.O. Nevska, O.A. Pohosian, K.O. Goncharuk, O.O. Chernenko, I.V. Hymanyk, A.R. Korol

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