Eye Movement Impairment Recovery in a Gaucher Patient Treated with Miglustat by Agostino Accardo, Stefano Pensiero, Giovanni Ciana, Fulvio Parentin, Bruno Bembi

“…In Gaucher Disease (GD) the enzyme (imiglucerase) replacement therapy (ERT) is not able to stop the progression of the neurological involvement, while the substrate reduction therapy (SRT), performed by N-Butyldeoxynojirimycin (miglustat), is an alternative that should be evaluated. …”
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Treatment response rate and life prognosis at autoimmune liver diseases by K. V. Ivashkin, Ye. N. Shirokova, V. T. Ivashkin

“…Appropriate and long-term (for 12–24 months) therapy of autoimmune diseases in most cases allows to achieve sustained response and in several folds surpasses efficacy of short courses (6–12 months).…”
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Mesenchymal Stromal Cells and Tissue-Specific Progenitor Cells: Their Role in Tissue Homeostasis by Aleksandra Klimczak, Urszula Kozlowska

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Anti-Yo Mediated Paraneoplastic Cerebellar Degeneration Associated with Pseudobulbar Affect in a Patient with Breast Cancer by Allison N. Martin, Patrick M. Dillon, David E. Jones, David R. Brenin, David A. Lapides

“…She was given IVIG for paraneoplastic syndrome, antidepressants, and dextromethorphan-quinidine (Nuedexta), the first FDA-approved therapy for PBA. With multimodality therapy, she demonstrated significant improvement in neurologic and mood symptoms associated with PCD and PBA.…”
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Gab Adapter Proteins as Therapeutic Targets for Hematologic Disease by Sheetal Verma, Tamisha Vaughan, Kevin D. Bunting

“…The multifunctionality of Gab adapters might suggest that they would be too difficult to consider as candidates for “targeted” therapy. However, the one drug/one target approach is giving way to the concept of one drug/multiple target approach since few cancers are addicted to a single signaling molecule for survival and combination drug therapies can be problematic. …”
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Occurrence of Psoriatic Arthritis during Interferon Beta 1a Treatment for Multiple Sclerosis by Éric Toussirot, Matthieu Béreau, Marie Bossert, Imad Malkoun, Anne Lohse

“…Interferon beta (IFN-β) is the first line therapy of relapsing-remitting multiple sclerosis. …”
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The Pain System in Oesophageal Disorders: Mechanisms, Clinical Characteristics, and Treatment by Christian Lottrup, Søren Schou Olesen, Asbjørn Mohr Drewes

“…In gastro-oesophageal reflux diseases, proton pump inhibitors are the primary treatment option, surgery being reserved for patients with severe disease resistant to drug therapy. Functional oesophageal disorders are treated with analgesics, antidepressants, and psychological therapy. …”
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Konsep Stres Akademik Siswa by Mufadhal Barseli, Ifdil Ifdil, Nikmarijal Nikmarijal

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Phospholipase D, a Novel Therapeutic Target Contributes to the Pathogenesis of Neurodegenerative and Neuroimmune Diseases by Weiwei Zhang, Feiqi Zhu, Jie Zhu, Kangding Liu

“…Notably, recent advances in the development of tools for studying PLD therapy envisaged novel therapeutic interventions. …”
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Gene regulation and signaling transduction in mediating the self-renewal, differentiation, and apoptosis of spermatogonial stem cells by Cai-Mei He, Dong Zhang, Zuping He

“…This review could provide novel insights into the genetic regulation of normal and abnormal spermatogenesis and offer molecular targets to develop new approaches for gene therapy of male infertility.…”
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Lymphocyte-Predominant Hodgkin’s Disease in Children: A Case Study and Review of the Literature by James R. Stier, Robert J. Vasquez

“…Recent evidence supports the efficacy of targeted anti-CD20 therapy in NLPHL, though prospective data is limited. …”
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Ranitidine bismuth citrate: A review by N Chiba, RH Hunt, ABR Thomson

“…To avoid complications of H pylori infection, such as the development of recurrent duodenal and gastric ulcers, effective therapies are required for eradication of the infection. …”
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Inhalation Techniques Used in Patients with Respiratory Failure Treated with Noninvasive Mechanical Ventilation by Patrycja Rzepka-Wrona, Szymon Skoczynski, Dawid Wrona, Adam Barczyk

“…The administration of aerosolized medication is a basic therapy for patients with numerous respiratory tract diseases, including obstructive airway diseases (OADs), cystic fibrosis (CF), and infectious airway diseases. …”
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Overcoming immune evasion with innovative multi-target approaches for glioblastoma by Hai Su, Yin Peng, Yilong Wu, Xiaoli Zeng, Xiaoli Zeng, Xiaoli Zeng

“…Tumor immune evasion, facilitated by a multifactorial network, poses a significant challenge to effective therapy, as evidenced by the limited clinical benefits of monotherapies, highlighting the adaptive nature of immune evasion. …”
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Lithium-induced nephrogenic diabetes insipidus following improved medication compliance: a case report by Eugene Annor, Ishita Bhattacharya, Mary Bass, Emily M. Horvath

“…Abstract Background Nephrogenic diabetes insipidus is a rare, often underrecognized complication of long-term lithium therapy. Lithium-induced nephrogenic diabetes insipidus results from chronic renal exposure, leading to significant polyuria, dehydration, and hypernatremia. …”
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Biochemical Bone Turnover Markers and Osteoporosis in Older Men: Where Are We? by Pawel Szulc

“…In men receiving antiresorptive therapy for prostate cancer, zoledronate, denosumab and toremifene decrease significantly levels of bone resorption and bone formation markers. …”
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Addison’s Disease Presenting as Acute Renal Failure and Hyperkalemic Paralysis: A Rare Presentation by Kundan Jana, Kalyana Janga, Sheldon Greenberg, Amit Gulati

“…It is especially important to be vigilant of adrenal insufficiency in such patients as the hyperkalemia is resistant to standard therapy of insulin dextrose and can precipitate fatal arrhythmia if treatment is delayed.…”
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Pseudomembranous Colitis: An Update by Harpreet S Brar, Christina M Surawicz

“…Most cases are associated with antibiotic therapy that alters the fecal flora, allowing overgrowth of C difficile with production of its toxins. …”
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Konsep Adiksi Game Online dan Dampaknya terhadap Masalah Mental Emosional Remaja serta Peran Bimbingan dan Konseling by Emria Fitri, Lira Erwinda, Ifdil Ifdil

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Inefficacy or Paradoxical Effect? Uveitis in Ankylosing Spondylitis Treated with Etanercept by Bernd Raffeiner, Francesca Ometto, Livio Bernardi, Costantino Botsios, Leonardo Punzi

“…The frequency of these events is slightly higher during therapy with etanercept. The available TNFα blockers show different pharmacokinetics and pharmacodynamics yielding different biological effects. …”
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