Clinical Recommendations of the Russian Gastroenterological Association and Association of Coloproctologists of Russia on Diagnosis and Treatment of Constipation in Adults by V. T. Ivashkin, Yu. A. Shelygin, I. V. Maev, A. A. Sheptulin, D. V. Aleshin, S. I. Achkasov, E. K. Baranskaya, N. D. Kulikova, T. L. Lapina, A. I. Moskalev, M. F. Osipenko, E. A. Poluektova, V. I. Simanenkov, A. S. Trukhmanov, O. Yu. Fomenko, O. S. Shifrin

“…An effective therapy for constipation requires a correct diagnosis of its causes.…”
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Candidate antirheumatic genotherapeutic plasmid constructions have low immunogenicity by T. S. Nepomnyashchikh, T. V. Tregubchak, S. N. Yakubitskiy, O. S. Taranov, R. A. Maksyutov, S. N. Shchelkunov

“…Viral genes coding for immunomodulatory factors could be used to create new gene therapy products to treat RA and other human disease. …”
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Blood-based biomarkers in patients with non-small cell lung cancer treated with immune checkpoint blockade by Yo-Ting Tsai, Jeffrey Schlom, Renee N. Donahue

“…To date, analyses of tumor biopsies are the only parameter used to guide prognosis to ICI therapy. Tumor biopsies, however, are often difficult to obtain and tissue-based biomarkers are limited by intratumoral heterogeneity and temporal variability. …”
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Efficacy of low-dose rituximab versus immunosuppressants in refractory orbital inflammatory pseudotumors with intracranial extension by Yuyu Li, Mingming Sun, Xintong Xu, Biyue Chen, Xiyun Chen, Yuhang Wang, Quangang Xu, Huanfen Zhou, Shihui Wei

“…After methylprednisolone pulse therapy, we added 2 mg of tacrolimus per day, 1500 mg of mycophenolate mofetil per day, or 200 mg of rituximab at days 1 and 15, and then monitored those with CD19+ B cells of under 1% as adjuvant therapy.ResultsEleven patients (six males and five females) were included, with a mean age of 45.5 ± 11.8 years (age range: 21–64 years). …”
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Frequency and Prognostic Relevance of FLT3 Mutations in Saudi Acute Myeloid Leukemia Patients by Ghaleb Elyamany, Mohammad Awad, Kamal Fadalla, Mohamed Albalawi, Mohammad Al Shahrani, Abdulaziz Al Abdulaaly

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Persistent Cryptococcal Brain Infection despite Prolonged Immunorecovery in an HIV-Positive Patient by Tom Wingfield, Jo Baxter, Amit Herwadkar, Daniel du Plessis, Tom J. Blanchard, F. Javier Vilar, Anoop Varma

“…HIV-positive people starting combined antiretroviral therapy may develop immune reconstitution to latent or treated opportunistic infections. …”
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Is There a Role for Daratumumab Retreatment in Patients with Relapsed/Refractory Multiple Myeloma? by Davor Galusic, Ivan Krecak, Viktor Blaslov, Andela Krstulovic Opara, Toni Valkovic, Sandra Basic Kinda

“…Due to the cost and availability of bispecific T cell redirecting antibodies (BsAbs) and chimeric antigen receptor T cell therapy (CAR-T) in real-life settings in many countries, retreatment with daratumumab in subsequent lines of therapy might be a reasonable choice. …”
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AKI Epidemiology and Outcomes: A Retrospective Cohort Study from the Prenephrology Era by K. Asmus, S. Erfurt, O. Ritter, S. Patschan, D. Patschan

“…Four parameters were evaluated in particular: AKI incidence, in-hospital mortality, frequency of renal replacement therapy, and renal recovery during the stay at the hospital. …”
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Research progress of moxibustion in patients with chronic renal failure (艾灸在慢性肾功能衰竭患者中应用研究进展) by DENG Jianhua (邓建华), LI Mengya (李玉欣), WU Chunli (李梦雅), TIAN Chenchen (吴春丽), HU Fangfang (田晨晨)

“…This paper summarized the literature of application of moxibustion therapy for patients with chronic renal failure. Moxibustion therapy is able to slowing the progression of renal function, improve the regulation of immune function, reduce the urinary protein. …”
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iTRAQ-Based Proteomic Analysis of Visual Cycle-Associated Proteins in RPE of rd12 Mice before and after RPE65 Gene Delivery by Qinxiang Zheng, Yueping Ren, Radouil Tzekov, Shanshan Hua, Minghan Li, Jijing Pang, Jia Qu, Wensheng Li

“…The level of RALBP-1 was still below the normal level after gene therapy in rd12 mice, which may explain the delayed dark adaption in LCA patients undergoing similar therapy.…”
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Potential of albumin dialysis at terminal liver failure in patients with chronic liver diseases by O. E. Nikiforova, Ye. N. Bessonova, O. M. Lesnyak, O. A. Stroganova

“…The first (main group) included 25 patients, that received albumin dialysis in addition to traditional drug therapy. The second group (comparison group) included 40 patients who received only traditional pharmaceutical therapy. …”
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The Effect of Propolis Irrigation as an Adjunctive to Scaling and Root Surface Debridement on Periodontal Health Status, Glycemic Control and Biochemical Markers in Subjects with... by Hozan Wrya Azeez

“… Background: Periodontitis is the inflammation of supporting tooth structures; it is one of the six complications of diabetes, Propolis a local delivery agent can be used as an adjunct to non-surgical periodontal therapy. Aim: To assess the effect of Propolis as adjunctive to scaling and root surface debridement for the treatment of periodontitis patients with type 2 diabetes. …”
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Yersinia Infection with Clostridium Difficile Colitis by M.J. Fishman, M.A. Noble, H.J. Freeman

“…All patients seen during a two year period with diarrhea within four weeks of antibiotic therapy, a positive tool culture for C difficile and a positive stool cytotoxin assay specific for C difficile were investigated. …”
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A 19-year-old Patient with Recurrent Pruritus and Jaundice by K. S. Nezhdanov, E. N. Shirokova, Yu. O. Shulpekova, A. S. Ostrovskaya, M. S. Zharkova, V. T. Ivashkin

“…Past medical history was significant for recurrent aforementioned symptoms since 3 years old, that relapsed every 1–2 years and were usually ameliorated with conservative therapy. During recent years, frequency of relapses and recovery period increased, at the same time effectiveness of medical therapy decreased. …”
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Integrative mindfulness-based infant parenting program: theoretical foundations and a novel intervention protocol by Or Burstein, Zipi Teshale Zevin, Ronny Geva, Ronny Geva

“…To adapt mindful parenting practice for implementation in pediatric care settings and the specific needs and challenges of parenting infants, the current study introduces a novel theoretical framework, combining mindfulness with elements from calming cycle theory, dialectical behavior therapy (DBT), trauma-informed care, emotion-focused therapy, schema therapy, and Vygotsky’s learning theory. …”
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Multimodal Surgical and Medical Treatment for Extensive Rhinocerebral Mucormycosis in an Elderly Diabetic Patient: A Case Report and Literature Review by Paola Di Carlo, Roberto Pirrello, Giuliana Guadagnino, Pierina Richiusa, Antonio Lo Casto, Caterina Sarno, Francesco Moschella, Daniela Cabibi

“…Mono- or combination therapy with liposomal amphotericin B (L-AmB) and posaconazole (PSO) and withheld debridement is discussed. …”
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Effect of Continuous Positive Airway Pressure on Airway Inflammation and Oxidative Stress in Patients with Obstructive Sleep Apnea by Promsrisuk Tichanon, Khrisanapant Wilaiwan, Santamit Sopida, Pasurivong Orapin, Boonsawat Watchara, Intarapoka Banjamas

“…We determined the effectiveness of continuous positive airway pressure (CPAP) therapy in reducing fractional exhaled nitric oxide (FeNO) and malondialdehyde (MDA) levels in OSA patients. …”
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Rheopheresis in treatment of idiopathic sensorineural sudden hearing loss by Milan Kostal, Jakub Drsata, Milan Bláha, Miriam Lánská, Viktor Chrobok

“…Little is known about the efficacy of second-line therapies. Rheopheresis seems to be an effective therapeutic possibility. …”
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Faktor-faktor yang Mempengaruhi Kontraktur Sendi Lutut pada Penanganan Fraktur Femur Secara Operatif dan Non Operatif di RS. M. Djamil Padang by Yandri E Yandri E, Manjas M Manjas M, Rahmadian R Rahmadian R, Erkadius Erkadius

“…From this research we found the stiffness of the knee joint in operative therapy by 5 cases (13.2%) and non-operative therapy found 15 cases. (39.5%).…”
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Влияние курсового приема L-орнитин- L-аспартата на фиброз и стеатоз печени у больных ассоциированной с нарушениями метаболизма жировой болезнью печени (неалкогольной жировой болезн... by Е. V. Garanina

“…An impact study of the LOLA course therapy on inflammation, steatosis and liver fibrosis biomarkers in MAFLD.Materials and methods. …”
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