Palmoplantar plaque psoriasis responsive to upadacitinib: A report of two cases by Bohmyi Choi, Heidi Oi-Yee Li, Steven J Glassman

“…Palmoplantar plaque psoriasis is more resistant to therapy compared to other phenotypes of psoriasis. …”
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Achieving myoblast engraftment into intact skeletal muscle via extracellular matrix by Kitora Dohi, Yasuko Manabe, Nobuharu L. Fujii, Yasuro Furuichi

“…Cell therapy of skeletal muscles is a promising approach for the prevention of muscular diseases and age-related muscle atrophy. …”
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Recurrence of LV Thrombus in a Patient with Severe Ischaemic Cardiomyopathy Anticoagulated with Apixaban by Azhar Farooqui, Tin Lwin, Daniel Costa, Simon Hetherington, Raj Mattu

“…Although successful thrombus resolution has been reported with direct oral anticoagulants’ (DOACs’) recurrence/progression while resuming Apixaban therapy is yet to be reported. Case Presentation. …”
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Legionella-Associated Lung Abscess: Critical Pathogen or Minor Isolate? by Gordon CK Dow, Anthony W Chow

“…The patient later died with multisystem failure despite adequate antimicrobial therapy. Prior cases of legionella-associated lung abscess have occurred predominantly in corticosteroid-treated patients. …”
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Efficacy and Cost Benefit of Inhaled Corticosteroids in Patients Considered to Have Mild Asthma in Primary Care Practice by Paul O'Byrne, Lauren Cuddy, D Wayne Taylor, Stephen Birch, Joanne Morris, Jerry Syrotuik

“…OBJECTIVE: Inhaled corticosteroids are infrequently used as asthma therapy in patients considered to have mild asthma in primary care practice. …”
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Editorial: Infections in the intensive care unit, volume II by Lihui Wang, Bin Lin, Bin Lin, Zhongheng Zhang, Zhongheng Zhang, Yuetian Yu, Yuetian Yu

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Peritoneal Dialysis Drop-out: Causes and Prevention Strategies by Kunal Chaudhary

“…Peritoneal dialysis (PD) as a renal replacement therapy (RRT) has become wide spread since its inception more than twenty-five years back. …”
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Late onset cerebellar ataxia syndrome after non-paraneoplastic Lambert-Eaton myasthenic syndrome: a case study by David P. Randall, Matthew C. Randall

“…The patient required months of intensive and continued immunomodulating therapy.…”
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Esophageal Involvement in Wegener’s Granulomatosis: A Case Report and Review of the Literature by Glen A Fallows, Sean F Hamilton, Douglas S Taylor, S Bharati Reddy

“…These reports illustrate the need to consider odynophagia as a reflection of disease activity as opposed to complications of immunosuppressive therapy.…”
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Mechanism of hsa_circ_0069443 promoting early pregnancy loss through ALKBH5/FN1 axis in trophoblast cells by Bai-xue Li, Mei-yao Wu, Zhi-hui Wang, Dong-mei Zhou, Jian-qi Li, Bing-feng Lu, Xiao-ling Lin, Yang Zhao, Xiu-jie Sheng

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Tumor microenvironment-responsive engineered hybrid nanomedicine for photodynamic-immunotherapy via multi-pronged amplification of reactive oxygen species by Jinglin Zou, Cong Jiang, Qiangsheng Hu, Xinlin Jia, Shuqi Wang, Shiyue Wan, Yuanqing Mao, Dapeng Zhang, Peng Zhang, Bin Dai, Yongsheng Li

“…Abstract Reactive oxygen species (ROS) is promising in cancer therapy by accelerating tumor cell death, whose therapeutic efficacy, however, is greatly limited by the hypoxia in the tumor microenvironment (TME) and the antioxidant defense. …”
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The prognostic role of vasculoendothelial growth factor A in patients with ST-segment elevation acute myocardial infarction during 6-months follow-up period by N.P. Kopytsya, I.M. Кutya, I.V. Rodionova, Ya.V. Hilova

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A multicenter, cross‐sectional analysis to assess the safety and usage pattern of brivaracetam in the management of partial‐onset seizure with BAEs—BREEZE study: A post‐hoc analysi... by Arvind Sharma, Krishnaprasad Korukonda, Amit Haldar, Usha Kant Misra, R. V. Anand, Yakshdeep Dave, Girish Kulkarni

“…Many patients with epilepsy who are not able to tolerate the other ASM including levetiracetam (LEV) primarily due to behavioral side effects improves tolerability post switch to BRV, additionally results are consistent either BRV being used as an adjuvant therapy or as monotherapy therapy.…”
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Revealing the Neuroimaging Mechanism of Acupuncture for Poststroke Aphasia: A Systematic Review by Boxuan Li, Shizhe Deng, Bomo Sang, Weiming Zhu, Bifang Zhuo, Menglong Zhang, Chenyang Qin, Yuanhao Lyu, Yuzheng Du, Zhihong Meng

“…Neuroimaging technology provides a visualized way to explore cerebral neural activity, which helps reveal the therapeutic effect of acupuncture therapy. In this systematic review, we aim to reveal and summarize the neuroimaging mechanism of acupuncture therapy on poststroke aphasia to provide the foundation for further study. …”
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First-in-human phase 1 study of the arginase inhibitor INCB001158 alone or combined with pembrolizumab in patients with advanced or metastatic solid tumours by Michael Smith, Aung Naing, Todd Bauer, Kyriakos P Papadopoulos, Osama Rahma, Elena Garralda, Glenn J Hanna, Michael J Pishvaian, Xuejun Chen, Sven Gogov, Omar Saavedra, Howard Kallender, LuLu Cheng, Emil Kuriakose

“…The most common INCB001158-related AEs were fatigue (n=10/107 (9.3%)) and nausea (n=10/107 (9.3%)) with monotherapy and diarrhoea (n=24/147 (16.3%)) and fatigue (n=22/147 (15.0%)) with combination therapy. The highest response rate was seen in the anti–PD-1/PD-L1–naive combination therapy group with head/neck squamous cell carcinoma (overall response rate, 19.2%; 4/26 partial responses, 1/26 complete response). …”
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Quantitative accuracy of preclinical in ovo PET/MRI: influence of attenuation and quantification methods by Theresa Balber, Katarína Benčurová, Manuela Mayrhofer, Joachim Friske, Martin Haas, Claudia Kuntner, Thomas H. Helbich, Marcus Hacker, Markus Mitterhauser, Ivo Rausch

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Self-reported health, persistent symptoms, and daily activities 2 years after hospitalization for COVID-19 by Roda Alhasan, Lena Rafsten, Lena Rafsten, Alexandra C. Larsson, Alexandra C. Larsson, Katharina S. Sunnerhagen, Katharina S. Sunnerhagen, Katharina S. Sunnerhagen, Hanna C. Persson, Hanna C. Persson

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Impact of adjunctive tolvaptan on sympathetic activity in acute heart failure with preserved ejection fraction by Shunsuke Tamaki, Takahisa Yamada, Takashi Morita, Yoshio Furukawa, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Masahiro Seo, Makoto Abe, Jun Nakamura, Kyoko Yamamoto, Kiyomi Kayama, Masatsugu Kawahira, Kazuya Tanabe, Kunpei Ueda, Takanari Kimura, Daisuke Sakamoto, Yuto Tamura, Takeshi Fujita, Masatake Fukunami

“…We aimed to evaluate the effect of adjunctive tolvaptan therapy on CSNA in ADHF patients with preserved left ventricular ejection fraction (LVEF). …”
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The diagnostic value and efficacy evaluation of lung ultrasound score in neonatal respiratory distress syndrome: a prospective observational study by Jian Dong, Yuhong Deng, Jin Tong, Tingting Du, Wenguang Liu, Yan Guo

“…Surfactant replacement therapy was administered to patients who were diagnosed with neonatal respiratory distress syndrome and met the criteria for medication. …”
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Clinical Significance of Screening Electrocardiograms for the Administration of Propranolol for Problematic Infantile Hemangiomas by James D. Phillips, Tyler Merrill, J. Reed Gardner, R. Thomas Collins, Jenika Sanchez, Adam B. Johnson, Brian K. Eble, Larry D. Hartzell, Jay M. Kincannon, Gresham T. Richter

“…Screening ECGs prior to propranolol therapy are abnormal in nearly 14% of patients with PIH but are unlikely to preclude therapy. …”
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