Delayed PCI 12 Hours after the Onset of Symptoms Is Associated with Improved Outcomes for Patients with ST-Segment Elevation Myocardial Infarction: A Real-World Study by Wen-Juan Xiu, Hai-Tao Yang, Ying-Ying Zheng, Yi-Tong Ma, Xiang Xie

“…The purpose of this study was to compare delayed PCI and medication therapy beyond the recommended time window of 12 h after the onset of symptoms on the outcomes of STEMI patients. …”
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Specific types of male infertility are correlated with T cell exhaustion or senescence signatures by Giada Amodio, Giorgia Giacomini, Luca Boeri, Massimiliano Raffo, Simone Cilio, Edoardo Pozzi, Federico Belladelli, Fausto Negri, Anna Maria Ferrara, Alessia d’Arma, Francesca Romana Santoni de Sio, Luca Pagliardini, Enrico Papaleo, Eugenio Ventimiglia, Massimo Alfano, Francesco Montorsi, Andrea Salonia, Silvia Gregori

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Prognosis and cardiotoxicity associated to adjuvant trastuzumab for breast cancer: real world study in a public health system by Ana Elisa Ribeiro da Silva Cabello, César Cabello, Susana Oliveira Botelho Ramalho, Otávio Rizzi Coelho, Otávio Rizzi Coelho-Filho, Helymar da Costa Machado, Délio Marques Conde, Luiz Carlos Zeferino

“…Methods: This was a retrospective cohort study that included 255 HER2-positive breast cancer patients who received adjuvant trastuzumab therapy. The inclusion criteria were a diagnosis of HER2-positive breast cancer and adjuvant trastuzumab therapy; disease stage I-III; <70 years; and a baseline echocardiogram showing a left ventricular ejection fraction (LVEF) ≥ 55%. …”
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Helicobacter pylori infection diagnostics and choice of eradication treatment: results of inquiry of doctors from different regions of Russian Federation by N. N. Dekhnich, R. S. Kozlov, O. A. Sablin, Ye. A. Prischepova

“…At the choice of second line antihelicobacter therapy mode components 34.8% of doctors complied to RGA guidelines. …”
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Descriptive retrospective cross-sectional study of rehabilitation care for poststroke users in Québec during the COVID-19 pandemic by Palak Vakil, Perrine Ferré, Johanne Higgins, Louis-David Beaulieu, Marie-Helene Milot, Marie-Hélène Boudrias

“…Demographic characteristics were collected, as well as indicators routinely collected in acute care and rehabilitation such as length of stay (LOS), the Functional Independence Measure and a number of physical/occupational therapy (PT/OT) sessions. Non-parametric statistical tests were used to compare variables among the three groups.Results COV+ users were older than COV− and pre-COV ones (p&lt;0.01) and were more disabled on admission to a rehabilitation centre (p&lt;0.01). …”
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Propranolol for Treatment of Infantile Hemangioma: Efficacy and Effect on Pediatric Growth and Development by Rachel A. Giese, Merit Turner, Mario Cleves, J. Reed Gardner, Gresham T. Richter

“…Monthly heights and weights of children undergoing propranolol therapy for IH were prospectively collected and tabulated. …”
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Extracellular vesicles in sputum of children with cystic fibrosis pulmonary exacerbations by Elad Ben-Meir, Lina Antounians, Shafinaz Eisha, Felix Ratjen, Augusto Zani, Hartmut Grasemann

“…Improvement in lung function (percent predicted forced expiratory volume in 1 s (ppFEV1)) with PEx therapy correlated with NE EV content (r=0.657, p=0.001). …”
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Deprescribing and Optimal Selection of Proton Pump Inhibitors (Contributions of the 26th United Russian Gastroenterology Week) by V. T. Ivashkin, I. V. Maev, A. S. Trukhmanov, A. A. Sheptulin, V. I. Simanenkov, T. L. Lapina, I. B. Khlynov, N. N. Dekhnich, O. D. Lopina, O. P. Alekseeva, N. V. Korochanskaya, M. F. Osipenko, P. V. Pavlov, S. S. Pirogov, G. N. Tarasova, Yu. P. Uspenskiy, D. N. Andreev, D. E. Rumyantseva

“…The choice of PPI may condition an optimal therapy for acid-related diseases.Conclusion. PPIs prevail in therapies for acid-related diseases and NSAID-induced upper GIT lesions. …”
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The role of polymorphic variants of arginase genes (<i>ARG1, ARG2</i>) involved in beta-2-agonist metabolism in the development and course of asthma by O. N. Savelieva, A. S. Karunas, Yu. Yu. Fedorova, R. R. Murzina, A. N. Savelieva, R. F. Gatiyatullin, E. I. Etkina, E. K. Khusnutdinova

“…The sensitivity to asthma therapy largely depends on the interaction of genetic and epigenetic factors, which account for about 50–60 % of variability of therapeutic response. …”
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A meta-analysis of risk factors for cardiovascular adverse events with anthracycline based chemotherapy in lymphoma patients by Bo Dai, Jingjing Xu, Baiyan Wang

“…Anthracyclines, hypertension, radiation therapy, diabetes, smoking, age, gender, hyperlipidemia, and obesity were meta-analyzed using a fixed or random effects model. …”
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Risk Factors of Upper Limb Lymphedema after Breast Cancer Surgery in Women by Jinghui HUANG, Feng HUANG, Pei ZHU, Shuainan SHEN, Kefan CAO, Cheng LIU, Fanfu FANG, Bai LI

“….), the tumor data (pathological type, stage, postoperative hormone receptor, the Her-2, number of lymph node dissection, number of positive lymph nodes, etc.) and the treatment data (surgery way, axillary lymph node processing way, whether to accept radiation therapy, whether to accept postoperative chemotherapy, chemotherapy program, chemotherapy cycles, whether to accept endocrine therapy, endocrine medication and medication time, etc.), establishing the clinical data bases of BCRL. …”
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Cisplatin and lipopolysaccharide co-administration for renal injury model in mice by Sae-Byeok Hwang, Soon-Suk Kang, Yeonmi Lee, Eunju Kang

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Case Report: Combined Autoimmune Pancreatitis, Ulcerative Colitis and Sclerosing Cholangitis in 28-y.o. Patient by A. R. Khurmatullina, A. V. Okhlobystin, L. N. Androsova, R. T. Rzayev, A. S. Tertychnyy, A. P. Kiryukhin, O. Z. Okhlobystina, M. S. Zharkova, O. S. Shifrin, V. T. Ivashkin

“…The patient was recommended to receive biologic therapy for UC remission induction.Conclusion. Differential diagnostics of combined autoimmune lesions of the liver, the pancreas and colon may be complicated and carried out ex juvantibus according to response to immunosuppressive therapy.…”
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Rekomendasi Pemberian Layanan Terapi Trombolisis (rt-PA) Untuk Pasien Stroke Iskemik Akut: Pendekatan Pengambilan Keputusan Multi Kriteria by Jidin Abdullah, Dikky Indrawan, Popong Nurhayati

“…The multi-criteria combination and alternative strategies are assessed using AHP to determine the criteria that have the greatest influence on thrombolysis therapy recommendations, and the alternative strategy priority that can improve thrombolysis therapy services. …”
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Effect of Yijinjing Training on Balance Function and Plantar Pressure of Stroke Patients by LUO Kailiang, JIN Xueming, MA Shujie, XUE Xin, LIU Xinhao, MA Xinran, HU Jun

“…The control group received routine rehabilitation therapy, including exercise therapy, occupational therapy, electrotherapy and acupuncture therapy, once a day, five days a week, continuous treatment for four weeks. …”
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Psychometric Testing of the CHAMPS Questionnaire in French Canadians with COPD by Susanne Mak, Jean Bourbeau, Nancy E. Mayo, Sharon Wood-Dauphinee, Judith E. Soicher

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Integration of a specialist pharmacist-led multidisciplinary team in primary care: preventing strokes in people with atrial fibrillation across North East London by Riyaz Patel, Sotiris Antoniou, Shabana Ali, Mital Patel, Matt Kearney, Jagjot Kaur Chahal, John Robson, Paul Wright, Afzal Sohaib, Richard Clements, Angela Theodoulou

“…The second priority was patients on dual antithrombotic therapy to determine if antiplatelet therapy could be stopped to minimise bleeding risk.At baseline (March 2020), nationally available data (extracted from CVDPREVENT) showed that 81% of patients with AF at high ischaemic risk across the three selected boroughs were anticoagulated. …”
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Sustained Intraocular Pressure Rise after the Treat and Extend Regimen at 3 Years: Aflibercept versus Ranibizumab by Alper Bilgic, Laurent Kodjikian, Jay Chhablani, Anand Sudhalkar, Megha Trivedi, Viraj Vasavada, Vaishali Vasavada, Shail Vasavada, Samaresh Srivastava, Deepak Bhojwani, Aditya Sudhalkar

“…Follow-ups and use of appropriate therapy can be determined correspondingly.…”
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Effects of dapagliflozin on heart rate variability, cardiac function, and short-term prognosis in early-onset post-myocardial infarction heart failure by Le Zhou, Mingyuan Niu, Wei Chen, Qian Hu, Yi Chen, Xiaohong Geng, Jiani Gu

“…ObjectiveTo investigate the effects of dapagliflozin, in addition to standard therapy, on heart rate variability (HRV), soluble growth stimulation expressed gene 2 protein (sST2), N-terminal pro B-type natriuretic peptide (NT-proBNP), and echocardiographic parameters in patients with early-onset post-myocardial infarction heart failure (HF).MethodsA total of 98 patients with early-onset post-myocardial infarction HF were enrolled and randomly divided into a control group (n = 48, receiving standard therapy) and an observation group (n = 50, receiving standard therapy plus dapagliflozin 10 mg daily). …”
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Hepatitis B care cascade among people with HIV/HBV coinfection in the North American AIDS Cohort Collaboration on Research and Design, 2012-2016. by Jessica Kim, Craig W Newcomb, Dean Carbonari, Jessie Torgersen, Keri N Althoff, Mari M Kitahata, Marina B Klein, Richard D Moore, K Rajender Reddy, Michael J Silverberg, Angel M Mayor, Michael A Horberg, Edward R Cachay, Joseph K Lim, M John Gill, Kara Chew, Timothy R Sterling, Mark Hull, Eric C Seaberg, Gregory D Kirk, Sally B Coburn, Raynell Lang, Kathleen A McGinnis, Kelly A Gebo, Sonia Napravnik, H Nina Kim, Vincent Lo Re, North American AIDS Cohort Collaboration on Research and Design of IeDEA

“…Among 3,953 persons with laboratory-confirmed HBV (median age, 50 years; 6.5% female; 43.8% were Black; 7.1% were Hispanic), 3,592 (90.9%; 95% confidence interval, 90.0-91.8%) were prescribed tenofovir-based antiretroviral therapy or entecavir along with their antiretroviral therapy regimen, 2,281 (57.7%; 95% confidence interval, 56.2-59.2%) had HBV DNA measured while on therapy, and 1,624 (41.1%; 95% confidence interval, 39.5-42.6) achieved an undetectable HBV DNA during HBV treatment. …”
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