Harnessing nanotechnology for cancer treatment by Jiajun Zhu, Jiajun Zhu, HaeJu Lee, HaeJu Lee, Ruotong Huang, Ruotong Huang, Jianming Zhou, Jingjun Zhang, Xiaoyi Yang, Wenhan Zhou, Wangqing Jiang, Shuying Chen

“…Nanotechnology has become a groundbreaking innovation force in cancer therapy, offering innovative solutions to the limitations of conventional treatments such as chemotherapy and radiation. …”
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A Network Investigation on Idiopathic Hypogonadotropic Hypogonadism in China by Weiwei Zhao, Hongying Ye, Xiaolong Zhao, Zhaoyun Zhang, Shouyue Sun, Yiran Jiang, Min He, Cheng Xu, Renming Hu, Yiming Li

“…The results of our cross-sectional study showed the effectiveness of hormone replacement therapy for IHH and implied that gonadotropin and androgen replacement therapy may be superior to gonadotropin treatment alone.…”
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Effect of HBeAg/anti-HBe coexistence on HBeAg seroconversion in treatment-naïve chronic hepatitis B patients with peginterferon-α by Kaimin Song, Huitong Wang, Dawu Zeng, Yunyun Qian, Zhixiang Guo, Huatang Zhang, Yijuan Zheng, Yongjun Zhou, Xueping Yu, Zhijun Su

“…Background: As an uncommon serological pattern, the effect of hepatitis B e antigen/anti-hepatitis B e (HBeAg/anti-HBe) coexistence on peginterferon-α (Peg-IFN-α) therapy in patients with chronic hepatitis B (CHB) remains unknown. …”
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Efficacy of Kolofort in Combined Functional Gastroenterological Pathology: an Open Study by Yu. P. Uspenskiy, O. S. Mirzoev, Yu. A. Fominykh, A. A. Gnutov, S. V. Polyushkin

“…All patients received Kolofort 2 times a day, 2 tablets per dose for 28 days.Results. The Kolofort therapy improved the clinical symptoms according to the “7x7” questionnaire; the primary mean total score was 17.7 ± 3.6, decreased to 10.3 ± 2.5 past 14 days (p < 0.0001) and to 7.6 ± 1.5 - past 28 days of therapy (p < 0.0001). …”
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Disparities in Opioid Use Disorder Treatment Admissions in the United States by Peter J. Mallow, Michael Mercado, Michael Topmiller

“…The fully saturated regression results found that the odds of Cincinnati individuals receiving planned medication-assisted therapy were 0.497 (95% CI, 0.451–0.546; P value < 0.001). …”
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Protocol for evaluating the effects of integrating music with taekwondo training in children with autism spectrum disorder: A randomized controlled trial. by Clare C W Yu, Kam M Mok, Emma Mak, Chun T Au, Dorothy F Y Chan, Stanley Wu, Raymond C K Chung, Matthew C K Ip, Simpson W L Wong

“…In the "Taekwondo training with elements of music therapy" group, elements of music therapy will be incorporated into the Taekwondo training. …”
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Platelet Rich Plasma in the Treatment of Bisphosphonate-Related Osteonecrosis of the Jaw: Personal Experience and Review of the Literature by F. Longo, A. Guida, C. Aversa, E. Pavone, G. Di Costanzo, L. Ramaglia, F. Ionna

“…In our study, we considered 72 patients with BRONJ with nonsurgical therapy, surgical therapy, and surgical therapy with platelet rich plasma (PRP) gel to evaluate its therapeutic effect in promoting ONJ wounds healing. …”
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Renal impairment as a risk factor for chemotherapy induced neutropenia in the treatment of trifluridine/thymidine phosphorylase inhibitor plus bevacizumab by Masatsune Shibutani, Hideki Tanda, Hiroaki Kasashima, Tatsunari Fukuoka, Shinichiro Kashiwagi, Kiyoshi Maeda

“…Abstract Although the phase III SUNLIGHT trial has demonstrated the survival benefit of the addition of bevacizumab (Bmab) to trifluridine/thymidine phosphorylase inhibitor (FTD/TPI), neutropenia, which frequently occurs during FDT/TPI + Bmab therapy, is a concern for clinicians. As TPI is excreted by the kidneys, the risk of adverse events is likely to be high in patients with an impaired renal function. …”
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First-line glaucoma monotherapy medication patterns in Finland during 1995-2019 based on a population-based study. by Petri K M Purola, Seppo V P Koskinen, Hannu M T Uusitalo

“…Timolol fixed-combinations were the most common second-line glaucoma therapy with a share of 39% after 5 years of follow-up.…”
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Triggers for Palliative Care consultation and its modalities in non-malignant mechanically ventilated patients in the Intensive Care Unit: A prospective observational study by Mansi Suresh, Souvik Chaudhuri, Krithika Rao, Pratibha Todur

“…APACHE II score ≥25 even after seven days of invasive mechanical ventilation and aggressive medical therapy in ICU, Charlson comorbidity index (CCI) score ≥5 and ≥2 hospitalizations in the preceding two years are triggers of PC consultation. …”
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Is Hydroxyurea Treatment Changing the Life of Children with Sickle Cell Disease? by Mohammed Ali Al Sabbah, Mahmoud Radaideh, Shafeeka Mohammed Saleh, Sura Ahmed Al-Doory, Amal Mahmoud Abdalqader, Fatima Farid Mir, Aya Mohammed

“…In the United Arab Emirates, our study is the first to assess the effects of hydroxyurea therapy in pediatric SCD patients. Methods: We conducted a retrospective cross-sectional study on 100 patients aged 2–13 years who were diagnosed with SCD, under regular outpatient follow-up with pediatric hematology clinic and receiving hydroxyurea therapy for at least 2 years. …”
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Mortality Related Risk Factors in High-Risk Pulmonary Embolism in the ICU by Begüm Ergan, Recai Ergün, Taner Çalışkan, Kutlay Aydın, Murat Emre Tokur, Yusuf Savran, Uğur Koca, Bilgin Cömert, Necati Gökmen

“…The treatment of choice for group 1 was thrombolytic therapy in 29 (70.7%) and anticoagulation in 12 (29.3%) patients. …”
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Clinical Characteristics and Risk Factors for Multidrug-Resistant Enterobacter cloacae Complex Bacteremia in a Chinese Tertiary Hospital: A Decade Review (2013&ndash;2022) by Han M, Hua M, Xie H, Li J, Wang Y, Shen H, Cao X

“…MDR ECC accounted for 30.9% (58/188). Previous antibiotic therapy was an independent risk factor for MDR ECC (OR = 3.193, P < 0.020), while appropriate antibiotic therapy significantly reduced the risk (OR = 0.279, P < 0.001). …”
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Surgical Treatment Patterns, Healthcare Resource Utilization, and Economic Burden in Patients with Tenosynovial Giant Cell Tumor Who Underwent Joint Surgery in the United States by Feng Lin, Winghan J. Kwong, Sherry Shi, Irina Pivneva, Eric Q. Wu, John A. Abraham

“…Opioids and nonsteroidal anti-inflammatory drugs (NSAIDs), and physical therapy, occupational therapy, and rehabilitation services, were commonly used during baseline (45%, 40%, and 30%, respectively). …”
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Analgesia Evaluation of 2 NSAID Drugs as Adjuvant in Management of Chronic Temporomandibular Disorders by Fernando Kurita Varoli, Murillo Sucena Pita, Sandra Sato, João Paulo Mardegan Issa, Cássio do Nascimento, Vinícius Pedrazzi

“…Statistical analysis has shown that, after 10 days of treatment, all therapies were effective for pain relief. NSAID therapy promoted analgesia on the third day, while placebo only promoted analgesia in the eighth day. …”
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Effects of Exercise Training Combined with Increased Physical Activity to Prevent Chronic Pain in Community-Dwelling Older Adults: A Preliminary Randomized Controlled Trial by Tatsuya Hirase, Hideki Kataoka, Shigeru Inokuchi, Jiro Nakano, Junya Sakamoto, Minoru Okita

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Central Giant Cell Tumour-A Case Series by Balaji V M, Pankaja Gupta, Nini George, Smile Singla, Swathy Sridhar

“…Conservative treatment modalities such as interferon alpha therapy calcitonin therapy and intralesional corticosteroid injections can significantly reduce postoperative morbidity however it is important to follow up on these cases for an extended period in order to study the effects and potential recurrence of these cases. …”
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A Gastroenterologist’s Perspective of The Medical Management of Patients with Crohn’s Disease and Ulcerative Colitis by ABR Thomson

“…Medical therapy in patients with inflammatory bowel disease (IBD) has specific objectives that need to be remembered when considering any form of intervention. …”
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Cholestasis in Crohn's Disease: A Diagnostic Challenge by Nir Hilzenrat, Esther Lamoureux, Averell Sherker, Albert Cohen

“…The second episode, at the time of an exacerbation of his colitis, was characterized by moderate portal inflammation on liver biopsy and resolved quickly while he was on corticosteroid therapy. The most recent episode, occurring when the bowel disease was quiescent, was due to granulomatous hepatitis and resolved clinically with no specific therapy. …”
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How Many Diseases Are Colorectal Cancer? by A. Greystoke, S. A. Mullamitha

“…The development of personalised therapy and mechanism-targeted agents in oncology mandates the identification of the patient populations most likely to benefit from therapy. …”
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