Polyclonal Recipient nTregs Are Superior to Donor or Third-Party Tregs in the Induction of Transplantation Tolerance by Nina Pilat, Christoph Klaus, Karin Hock, Ulrike Baranyi, Lukas Unger, Benedikt Mahr, Andreas M. Farkas, Fritz Wrba, Thomas Wekerle

“…We have previously reported successful induction of chimerism and tolerance using cell therapy with recipient T regulatory cells (Tregs) to avoid cytotoxic recipient treatment. …”
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Plasmapheresis for extracorporeal membrane oxygenation (ECMO)-induced hemolysis in infants by Budhu Gail, Morris-Whyte Kaydeen, Constantinescu Alexandru R.

“…Characterized by elevated plasma-free hemoglobin (PFH), intravascular hemolysis is associated with cytotoxic effects leading to renal replacement therapy (RRT), longer ECMO runs, and mortality. Therapeutic plasma exchange (TPE) in tandem with ECMO was described as a therapy for various pathologic conditions, but there are no Extracorporeal Life Support Organization (ELSO) guidelines for the treatment of ECMO-induced hemolysis. …”
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Does Gender Influence Physiological Tolerance in Resuscitators When Using Personal Protection Equipment against Biological Hazards? by Francisco Martín-Rodríguez, José Luis Martín Conty, Verónica Casado Vicente, Pedro Arnillas Gómez, Alicia Mohedano-Moriano, Miguel Ángel Castro Villamor

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Transcatheter Arterial Chemoembolization Based on Hepatic Hemodynamics for Hepatocellular Carcinoma by Satoru Murata, Takahiko Mine, Tatsuo Ueda, Ken Nakazawa, Shiro Onozawa, Daisuke Yasui, Shin-ichiro Kumita

“…Patients with intermediate-stage HCC benefit from transcatheter arterial chemoembolization (TACE), and those diagnosed at an advanced stage receive sorafenib, a multikinase inhibitor, or conservative therapy. Most patients receive palliative or conservative therapy only, and approximately 50% of patients with HCC are candidates for systemic therapy. …”
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Mesenchymal Stem Cells May Alleviate the Intervertebral Disc Degeneration by Reducing the Oxidative Stress in Nucleus Pulposus Cells by Yongzhao Zhao, Qian Xiang, Yunzhong Cheng, Jialiang Lin, Shuai Jiang, Weishi Li

“…Background. Stem cell therapy is a promising therapeutic modality for intervertebral disc degeneration (IDD). …”
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Evaluating the effectiveness of adjuvant radiotherapy in addition to surgery versus surgery alone at improving oncologic outcomes for early stage buccal carcinoma: a systematic rev... by Corliss Ann Elizabeth Best, Alexandra Elizabeth Quimby, Brittany Ann Barbara Best, Dean Fergusson, Hussain Alsaffar

“…Abstract Objective To systematically review the evidence to evaluate oncologic outcomes for patients with early stage buccal squamous cell carcinoma treated with surgery versus surgery and adjuvant radiation therapy. Data sources Ovid MedLine, EMBASE, Google Scholar, PubMed. …”
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Cardiac Effects of Thyrotropin Oversuppression with Levothyroxine in Young Women with Differentiated Thyroid Cancer by Kyung-Soon Hong, Jung-Woo Son, Ohk Hyun Ryu, Moon-Gi Choi, Ji Yeon Hong, Seong Jin Lee

“…This study shows that TSH suppression therapy in women with DTC may be safe with respect to cardiac functions and structures despite intermittent oversuppression of TSH during long-term suppressive therapy. …”
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Priming Adipose-Derived Mesenchymal Stem Cells with Hyaluronan Alters Growth Kinetics and Increases Attachment to Articular Cartilage by Peter Succar, Michael Medynskyj, Edmond J. Breen, Tony Batterham, Mark P. Molloy, Benjamin R. Herbert

“…Biological therapeutics such as adipose-derived mesenchymal stem cell (MSC) therapy are gaining acceptance for knee-osteoarthritis (OA) treatment. …”
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Impact of the Siewert Classification on the Outcome of Patients Treated by Preoperative Chemoradiotherapy for a Nonmetastatic Adenocarcinoma of the Oesophagogastric Junction by Laurence Moureau-Zabotto, Eric Teissier, Didier Cowen, David Azria, Steve Ellis, Michel Resbeut

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Tocilizumab, an Exploratory Treatment for Severe COVID-19 Patients by Yong Wang, Yongfeng Chen, Xiangdong Zhou

“…In the present study, we will discuss and evaluate the treatment response of TCZ therapy in patients with COVID-19. The clinical characteristics, treatment, laboratory parameters of IL-6, C-reactive protein (CRP), lymphocyte counts before and after TCZ therapy, and clinical outcomes in the 13 patients with COVID-19 were retrospectively evaluated according to the related medical records. …”
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Pregnancy and COVID-19: Comparing ICU Outcomes for Pregnant and Nonpregnant Women by Małgorzata Lipińska-Gediga, Waldemar Goździk, Jakub Śmiechowicz, Barbara Adamik

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Relationships between structural changes, marker of apoptosis and metabolic parameters in the retina of rats with diabetes and myopia by I.M. Mikheytseva, А. Ahmed, S.G. Kolomiichuk, O. V. Artemov

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Coproducing healthcare service improvement for people with common mental health disorders including psychotic experiences: a study protocol of a multiperspective qualitative study by Alexandros Georgiadis, Robbie Duschinsky, Jesus Perez, Peter B Jones, Debra Russo, Clare Knight, Emma Soneson, Mary Dixon-Woods

“…Our sample will include (1) approximately 15 service users who will be receiving therapy or will have completed therapy at the time of recruitment, (2) approximately 15 service users who initiated treatment but withdrew, (3) approximately 15 therapists each with at least 4-month experience in a step-3 IAPT setting and (4) three IAPT managers. …”
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Hepatocytic Differentiation Potential of Human Fetal Liver Mesenchymal Stem Cells: In Vitro and In Vivo Evaluation by Hoda El-Kehdy, Guillaume Pourcher, Wenwei Zhang, Zahia Hamidouche, Sylvie Goulinet-Mainot, Etienne Sokal, Pierre Charbord, Mustapha Najimi, Anne Dubart-Kupperschmitt

“…Standardization of their isolation, expansion, and differentiation may also support their use for liver cell-based therapy development.…”
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The impact of gender-affirming interventions on eating disorder diagnosis risk among transgender and gender-diverse individuals by Matthew Loria, Tomasz Tabernacki, Elad Fraiman, Jaime Perez, Jessica Abou Zeki, Julia Palozzi, Carly Goldblatt, Shubham Gupta, Kirtishri Mishra, Megan McNamara, Swagata Banik

“…Conclusions After undergoing gender-affirming medical therapy, the risk of eating disorder diagnosis increases for transfeminine individuals and decreases for transmasculine individuals. …”
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Hepatitis C Virus Clearance after Discontinuation of Pegylated Interferon Alpha-2a Monotherapy in a Child by Takeshi Endo, Koichi Ito, Tokio Sugiura, Kenji Goto

“…In conclusion, though antiviral therapy resulted in failure or incomplete therapy, a reduced viral load resulted in viral clearance in the present patient. …”
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Effect of Liraglutide on Serum TSH Levels in Patients with NAFLD and its Underlying Mechanisms by JiaoJiao Ye, Jing Xu, WenJie Wen, Bin Huang

“…After the therapy, the NAFLD and NASH groups showed significantly decreased TSH levels after liraglutide therapy compared with the corresponding baseline data. …”
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Phase 1 Trial of Autologous Bone Marrow Stem Cell Transplantation in Patients with Spinal Cord Injury by Zurab Kakabadze, Nickolas Kipshidze, Konstantine Mardaleishvili, Gocha Chutkerashvili, Irakli Chelishvili, Albrecht Harders, George Loladze, Gocha Shatirishvili, Nodar Kipshidze, David Chakhunashvili, Konstantine Chutkerashvili

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Conservative Surgical Management of Stage I Bisphosphonate-Related Osteonecrosis of the Jaw by Paolo Vescovi, Elisabetta Merigo, Marco Meleti, Maddalena Manfredi, Carlo Fornaini, Samir Nammour, Giovanni Mergoni, Amin Sarraj, Jose V. Bagan

“…Surgical interventions were performed, under local analgesia, in patients unresponsive for a period of six months to noninvasive treatments such as cycles of local or systemic antibacterial therapy combined or not to low level laser therapy, ozone therapy, or Hyperbaric Oxygen Therapy. …”
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The Efficacy and Safety of Dexamethasone Intravitreal Implant for Diabetic Macular Edema and Macular Edema Secondary to Retinal Vein Occlusion: A Meta-Analysis of Randomized Contro... by Li Xiaodong, Xie Xuejun

“…The incidence of high IOP (OR = 13.77, 95% CI: 4.96 to 38.18, P<0.00001) was significantly higher with DEX than with anti-VEGF therapy. Conclusions. In patients with DME and RVO-ME, DEX was more efficacious but slightly less safe than anti-VEGF therapy.…”
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