Effects of the Multidimensional Treatment on Pain, Disability, and Sitting Posture in Patients with Low Back Pain: A Randomized Controlled Trial by Tae-Sung In, Jin-Hwa Jung, Kyoung-Sim Jung, Hwi-Young Cho

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BONE MARROW MICROENVIRONMENT INVOLVEMENT IN T-MN: FOCUS ON MESENCHYMAL STEM CELLS by Maria Teresa Voso, Giulia Falconi, Emiliano Fabiani

“… Therapy-related myeloid neoplasms (t-MN) are a late complication of cytotoxic therapy (CT) used in the treatment of both malignant and non-malignant diseases. …”
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Sudden Vision Loss Secondary to Optic Nerve Infiltration as a Presenting Symptom of Metastatic Lung Adenocarcinoma by M. M. Shamim, M. Whaley, H. Rana, S. K. Jeffus, S. Bhatti, A. B. Sallam

“…We treated him with local radiation therapy to the left eye and systemic osimertinib (EGFR-TKI). …”
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Recent advances in the management of knee osteoarthritis: a narrative review by Viktor Shtroblia, Pavlo Petakh, Iryna Kamyshna, Iryna Halabitska, Oleksandr Kamyshnyi

“…Topical treatments, such as NSAIDs and capsaicin, offer significant pain relief with minimal systemic side effects and are suitable for initial therapy, together with nonpharmacologic interventions like exercise and, when relevant, weight loss. …”
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Lipid Peroxidation-Mediated Inflammation Promotes Cell Apoptosis through Activation of NF-κB Pathway in Rheumatoid Arthritis Synovial Cells by Geng Yin, Ying Wang, Xiao-min Cen, Min Yang, Yan Liang, Qi-bing Xie

“…However, some of the targeted therapies for inflammation reactions do not display significant clinical improvement after initiation of therapy. …”
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Optimal Molecular Methods in Detecting p190BCR-ABL Fusion Variants in Hematologic Malignancies: A Case Report and Review of the Literature by Rebecca J. Sonu, Brian A. Jonas, Denis M. Dwyre, Jeffrey P. Gregg, Hooman H. Rashidi

“…Patients with BCR-ABL1 positive hematologic malignancies and Philadelphia-like B-lymphoblastic leukemia (B-ALL) are potential candidates for targeted therapy with tyrosine kinase inhibitors (TKI). Before TKIs, patients with B-ALL had a much worse prognosis and current treatments with targeted TKI therapy have improved outcomes. …”
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Prospects of Using Microbiota Correction Methods in the Treatment of Inflammatory Bowel Disease by A. I. Akinshina, D. V. Smirnova, A. V. Zagainova, V. V. Makarov, S. M. Yudin

“…The present article examines key methods of microbiota correction (antibiotic therapy; pro-, pre- and metabiotic therapy; faecal microbiota transplantation) used in treating inflammatory bowel disease, as well as compares the clinical trial results of these methods.Key findings. …”
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Use of art as therapeutic intervention for enhancement of hand function in patients with rheumatoid arthritis: A pilot study by Sayali Khedekar, Apurv P Shimpi, Ashok Shyam, Parag Sancheti

“…Results: There was an improvement in hand functions (grip strength [P = 0.042], two-point pinch strength [P = 0.039], three-point pinch strength [P = 0.043], GAT [P = 0.043], JHFT [P = 0.043]), self-perception (AUSCAN [P = 0.043], MHQ [P = 0.043]), and quality of life (HAQ;P = 0.043) in art therapy patients which was similar to conventional therapy patients. …”
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Effect of Optimization of Glycaemic Control on Mannan-Binding Lectin in Type 1 Diabetes by Gry Høst Dørflinger, Charlotte Brink Holt, Steffen Thiel, Jakob Appel Østergaard, Troels Krarup Hansen

“…We measured MBL, fructosamine, and HbA1cat baseline and after 6 weeks in 52 type 1 diabetic patients following the change from conventional insulin therapy to insulin pump therapy. Results. After initiation of insulin pump therapy, the total daily insulin dose was significantly reduced (from 51 ± 18 IE/day to 39 ± 13 IE/day, P<0.0001). …”
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Severe Diverticulitis Associated to <i>Clostridioides difficile</i> Infection in a 91 Year Old Patient (Clinical Case) by A. A. Makushina, L.  N. Androsova, K. B. Puzakov, A. V. Okhlobystin, M. A. Tatarkina, O. S. Shifrin

“…Combined therapy of exacerbation of diverticular disease and C. difficile-associated disease made it possible to achieve a steady improvement of the condition.Conclusion. …”
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Aggressive Central Nervous System Relapse after Autologous Stem Cell Transplant in Multiple Myeloma: Case Reports and Literature Review by Rui Bergantim, Juliana Bastos, Maria José Soares, Bruno Carvalho, Pedro Soares, Cristina Marques, Jennifer Costa, José Eduardo Guimarães, Fernanda Trigo

“…There is no standard therapy for this extramedullary relapse, and a tailored and multiple therapy should be promptly started—intrathecal therapy, radiotherapy, and systemic therapy, including an immunomodulator.…”
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Early Poststroke Rehabilitation Using a Robotic Tilt-Table Stepper and Functional Electrical Stimulation by Alexey N. Kuznetsov, Natalia V. Rybalko, Vadim D. Daminov, Andreas R. Luft

“…Hemiparetic ischemic stroke survivors (age years, days after stroke) were assigned to 30 days of ROBO-FES (), ROBO (), or control () in addition to conventional physical therapy. Impedance cardiography and transcranial doppler sonography were performed before, during, and after training. …”
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Treatment of Extensive Plaque Psoriasis and Psoriatic Arthropathy using Methotrexate in a Patient with High Serum Alkaline Phosphatase by Suad HH, Muna Mohammed El Amin, Gad Allah Modawe, Osman Elbasheer

“…Recommendations: Methotrexate is recommended for the treatment of severe morbid forms of psoriasis. The biologic therapy for severe forms of psoriasis is now available and can be a good alternative for the treatment of severe forms of psoriasis in good centers and for patients who can afford and in patients with absolute contraindications to methotrexate therapy.…”
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Granulocyte-Monocyte Apheresis in Steroid-Dependent, Azathioprine-Intolerant/Resistant Moderate Ulcerative Colitis: A Prospective Multicenter Study by Gianni Imperiali, Arnaldo Amato, Maria Maddalena Terpin, Ivo Beverina, Aurora Bortoli, Massimo Devani, Chiara Viganò, Study Group on IBD (GSMII)

“…Apheresis might represent an alternative to biologic therapy or surgery in this specific subgroup of patients. …”
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Evaluation of the Inferior Vena Cava Diameter in Dehydrated Children Using Bedside Ultrasonography by Esra Akyüz Özkan, Mahmut Kılıç, Fatih Çalışkan, Ahmet Baydın

“…In this article, we aimed to evaluate IVC diameter with bedside US before and after the fluid therapy in dehydrated children. Methods. A total of 124 dehydrated patients were enrolled, aged 8 months to 17 years. …”
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A stumbling block in pancreatic cancer treatment: drug resistance signaling networks by Jinming Liu, Biao Zhang, Bingqian Huang, Kexin Zhang, Fujia Guo, Zhizhou Wang, Dong Shang, Dong Shang

“…However, PC is a “cold tumor” with a unique immunosuppressive tumor microenvironment (poor effector T cell infiltration, low antigen specificity), and targeting a single gene or pathway is basically ineffective in clinical practice. Targeted matrix therapy, targeted metabolic therapy, targeted mutant gene therapy, immunosuppressive therapy, cancer vaccines, and other emerging therapies have shown great therapeutic potential, but results have been disappointing. …”
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Improving Clinical, Cognitive, and Psychosocial Dysfunctions in Patients with Schizophrenia: A Neurofeedback Randomized Control Trial by Renata Markiewicz, Agnieszka Markiewicz-Gospodarek, Beata Dobrowolska, Bartosz Łoza

“…The aim of this study was to use neurofeedback (NF) training as the add-on therapy in patients with schizophrenia to improve their clinical, cognitive, and psychosocial condition. …”
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Clinical Practice Guidelines of Traditional Chinese Medicine Rehabilitation for Cardiopulmonary by Working Group of Clinical Practice Guidelines of Traditional Chinese Medicine Rehabilitation for Cardiopulmonary, Xihua LIU, Xiaoxu LI, Hongyan BI, Xianliang WANG, Xin ZHENG, Yuru YANG, Shijie HAO

“…The cardiopulmonary function training mainly includes the following aspects: pulmonary ventilation and lung capacity improvement training, airway clearance technology, respiratory muscle training, exercise training, acupuncture therapy, massage therapy, Taiji jar therapy, auricular therapy, guiding technique of TCM. …”
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Central Nervous System-related Conditions and Associated Healthcare Resource Use Among Japanese nmCRPC Patients Based on Retrospective Claims Data by Dianne A. Ledesma, Jonathan L. Chua, Susan S.H. Tang, Xiu W. Lim

“…**Background:** Japanese patients with prostate cancer are typically treated with primary androgen deprivation therapy (ADT), most commonly administered as a combination of a luteinizing hormone-releasing hormone (LHRH) agonist and an antiandrogen (AA). …”
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Canadian real-world study of access and clinical results using dupilumab for chronic rhinosinusitis with polyps by Shaun J. Kilty, Andrea Lasso

“…Abstract Background Dupilumab is the first monoclonal antibody therapy to be approved in Canada for the treatment of Chronic Rhinosinusitis with Nasal Polyps (CRSwNP). …”
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