Omeprazole: Inhibiting the Final Common Pathway to Acid Secretion - The Acid Pump by A.B.R. Thomson

“…More patients are free from symptoms earlier on omeprazole therapy than with the H2 receptor antagonists. Omeprazole is also effective in healing and symptom relief even where prolonged H2 receptor antagonist therapy has been unsuccessful. …”
Get full text

Impact of maternal and offspring smoking and breastfeeding on oesophageal cancer in adult offspring by Yixue Wang, Hongru Sun, Gen Li, Jingxue Xu, Siyu Wang, Shijie Zhang, Tianle Zhou, Tianshu Han, Changhao Sun, Jianqun Ma, Xiaoyuan Wang, Hang Yin

Get full text

Immune Toxicity with Checkpoint Inhibition for Metastatic Melanoma: Case Series and Clinical Management by Anna J. Lomax, Jennifer Lim, Robert Cheng, Arianne Sweeting, Patricia Lowe, Neil McGill, Nicholas Shackel, Elizabeth L. Chua, Catriona McNeil

“…We retrospectively evaluated the incidence, kinetics, and management of irAE in 41 patients receiving anti-PD-1 antibody therapy (pembrolizumab) for advanced melanoma. 63% received prior anti-CTLA-4 antibody therapy (ipilimumab). …”
Get full text

Early Driving Pressure Changes Predict Outcomes during Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome by Harry Magunia, Helene A. Haeberle, Philipp Henn, Martin Mehrländer, Peer O. Vlatten, Valbona Mirakaj, Peter Rosenberger, Michael Koeppen

“…Extracorporeal membrane oxygenation (ECMO) serves as a rescue therapy when systemic hypoxia persists despite conventional care for severe acute respiratory distress syndrome (ARDS). …”
Get full text

Tacrolimus and mycophenolate mofetil in corticosteroid-resistant hepatitis secondary to tislelizumab: a case report by Chang Jiang, Shanxian Guo

“…Besides, when tumor progression and IRH recurrence occur simultaneously, providing effective immunosuppressive therapy and reasonably arranging systemic anti-tumor therapy may bring clinical benefits to patients.…”
Get full text

Trimethoprim/sulfamethoxazole-induced acute renal failure: A case report by Gabriella Nucera, Valentina Raffaelli, Lisa Caliari, Giulia Cantoni, Pietro Marino

“…Subsequently, we started a new antibiotic therapy with trimethoprim/sulfamethoxazole (TMP/SMX) adjusted to renal functioning. …”
Get full text

Long-Term Effects of Activity Status in the Elderly on Cardiorespiratory Capacity, Blood Pressure, Blood Lipids, and Body Composition: A Five-Year Follow-Up Study by Eli Carmeli, Pini Orbach, David T. Lowenthal, Joav Merrick, Raymond Coleman

Get full text

Evaluation of the longitudinal deformation of left ventricle and its changes in myocardial infarction and coronary heart disease with obstructive coronary artery lesions by N.V. Tytarenko, M.P. Kopytsya, I.V. Rodionova, A.V. Kobets

“…In patients with myocardial infarction without ST-segment elevation, GLS measurement may assist in the selection of patients who need urgent reperfusion therapy. In coronary heart disease, GLS can complement the conventional assessment of wall movement; replace the need for additional non-invasive testing for some patients with suboptimal stress tests. …”
Get full text

The Persian Version of the "Participation Measure-3 Domains, 4 Dimensions": Translation, Cultural Adaptation, Face and Content Validity by Diba Sharifi, Laleh Lajevardi, Ghorban Taghizadeh, Akram Azad

“…Background and Objectives: Investigating the impact of occupational therapy interventions on the participation levels of adults with stroke is crucial due to its significant influence on their satisfaction and quality of life (QOL). …”
Get full text

Management of patients with dry eye syndrome with systemic autoimmune and infectious diseases by G.M. Chernakova, E.A. Kleshcheva

“…The common pathogenetic processes of development of DES in patients with systemic infectious and non-infectious diseases allows to consider the reduction of oxidative stress as the main direction of the drug therapy. Undoubtedly, systemic therapy of the underlying disease is mandatory, however,&nbsp;<br> it is the ophthalmologist’s responsibility to identify symptoms of tear production decrease against the background of these diseases, to establish the severity of DES and to prescribe therapy that improves the quality of life of patients.…”
Get full text

Estimating the Impact of Aging on Visual Function Using Useful Field of View (UFOV) with a Focus on the Population of Gangwon-do in Korea by Sang-Bin Na, Seong-Youl Choi, Da-Bin Jeon, Soo-Jin Moon, Jin-Keun Kim

Get full text

The Antinociceptive Effect of Light-Emitting Diode Irradiation on Incised Wounds Is Correlated with Changes in Cyclooxygenase 2 Activity, Prostaglandin E2, and Proinflammatory Cyto... by Yuan-Yi Chia, Chien-Cheng Liu, Guan-Ming Feng, Chia-Chih Alex Tseng, Kuo-Chuan Hung, Chih-Chieh Chen, Ping-Heng Tan

“…Behavioral tests and analysis of skin tissue were performed after LED therapy. Results. LED therapy attenuated the decrease in thermal withdrawal latency in all the irradiated groups and the decrease in the mechanical withdrawal threshold in the L-I group only. …”
Get full text

Use of Sildenafil in Pulmonary Arterial Hypertension: Findings from a U.S. Healthcare Claims Database by Ariel Berger, John Edelsberg, Simon Teal, Marko A. Mychaskiw, Gerry Oster

“…Post-index use of sildenafil was then examined in terms of the numbers of pharmacy claims and therapy-days, the medication possession ratio (MPR), and the incidence of therapy switching. …”
Get full text

Influence of alexithymia severity in the healthy population on the susceptibility to false interoceptive feedback by Hitomi Ikarashi, Hitomi Ikarashi, Naofumi Otsuru, Naofumi Otsuru, Sena Takahashi, Kazuaki Nagasaka, Kazuaki Nagasaka, Masayuki Hara, Hideaki Onishi, Hideaki Onishi

Get full text

Effects of Neural Load on Hamstring Stretching upon Flexibility, Maximum Isometric Strength, and Tibial Nerve Pressure Pain Threshold in Healthy Subjects: A Randomized Clinical Tri... by Carlos Fernández-del Rivero, Pablo García-Gil, Juan Mínguez-Cruz, Daniel Pecos-Martín, Samuel Fernández-Carnero, Alexander Achalandabaso-Ochoa, Daniel Rodríguez-Almagro

Get full text

Impact of Treatment on Rate of Biphasic Reaction in Children with Anaphylaxis by William Bonadio, Connor Welsh, Brad Pradarelli, Yunfai Ng

“…All BPR episodes occurred within the 0–4 hour interval after initiating therapy, whereas no patient manifested a BPR requiring an additional dose of IM EPI during the 4–48 hours after initiating therapy (P = <0.001, 95% CI 0–1.3%). …”
Get full text

Crosstalk between Macrophages and Mesenchymal Stem Cells Regulated by Biomaterials and Its Role in Bone Regeneration by Fan Gong, Thomas Groth, Chenlin Tu, Mingyan Zhao, Xinqia Huang, Jiaqi Chu

Get full text

Adult Intra-Thoracic Kidney: A Case Report of Bochdalek Hernia by Valeria Fiaschetti, Luca Velari, Eleonora Gaspari, Roberta Mastrangeli, Giovanni Simonetti

Get full text

Surveillance of HCC Patients after Liver RFA: Role of MRI with Hepatospecific Contrast versus Three-Phase CT Scan—Experience of High Volume Oncologic Institute by Vincenza Granata, Mario Petrillo, Roberta Fusco, Sergio Venanzio Setola, Elisabetta de Lutio di Castelguidone, Orlando Catalano, Mauro Piccirillo, Vittorio Albino, Francesco Izzo, Antonella Petrillo

Get full text

A comparative analysis in monitoring 24-hour urinary copper in wilson disease: sampling on or off treatment? by Isabelle Mohr, Patrick Lamade, Christophe Weber, Viola Leidner, Sebastian Köhrer, Alexander Olkus, Matthias Lang, Andrea Langel, Patrischia Dankert, Melanie Greibich, Silke Wolf, Holger Zimmer, Patrick Michl, Aurélia Poujois, Karl Heinz Weiss, Uta Merle

“…Methods Eighty-four patients with a confirmed diagnosis of WD treated with chelators (50% of patients with D-Penicillamine and 50% with trientine) and with pairwise 24-h-UCE values on-therapy and off-therapy were included in the analysis. …”
Get full text