Effect of Oral PUVAsol on the Quality of Life in Indian Patients Having Chronic Plaque Psoriasis by Pratik Gahalaut, Nitin Mishra, Puneet S. Soodan, Madhur K. Rastogi

“…PUVAsol has been successfully used for treating psoriasis instead of standard PUVA therapy in developing countries. However, data for PUVAsol therapy and its effect on QoL in psoriatic patients is meagre. …”
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Current landscape and future prospects of interleukin-2 receptor (IL-2R) agonists in cancer immunotherapy by Kengo Tanigawa, William L. Redmond

“…This review will explore IL-2 biology, the clinical application of HD IL-2 therapy, and the development of novel IL-2 R agonists for cancer immunotherapy.…”
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A prospective hospital-based study on C-reactive protein as a response predictor of antidepressant treatment in drug naïve patients with major depressive disorder by Didakamiwan Khonglah, Arghya Pal, Nitu Mallik, Debes Ray, Malay Ghosal, Rudraprasad Acharya

“…Aims: This study was conducted to determine the relationship between the level of CRP to remission rates after antidepressant therapy. Methods: Fifty patients of first episode MDD with no past history of antidepressant exposure and other medical comorbidity were recruited after obtaining consent for Escitalopram therapy. …”
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Congenital Hypothyroidism: An Unusual Combination of Biochemical Abnormalities by Ruchi Mantri, S. B. Bavdekar, Sushma U. Save

“…Following institution of oral thyroxin therapy, the serum bilirubin levels ameliorated (2.9 mg/dl) considerably by 15 days of therapy and the serum levels of AST (40 IU/dl) and ALT (20 IU/dl) got normalized. …”
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Efficacy of Nivolumab in a Patient with Metastatic Renal Cell Carcinoma and End-Stage Renal Disease on Dialysis: Case Report and Literature Review by Jawaher Ansari, Muhammad Ali, Ashraf Farrag, Arwa M. Ali, Abdulaziz Alhamad

“…In addition, there is uncertainty regarding drug dosing/pharmacokinetics, lack of safety and efficacy data, and potential for increased toxicity when using targeted therapy or immunotherapy for the management of patients with mRCC on dialysis. …”
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Mesenchymal Stem Cells in Restoration of Fertility at Experimental Pelvic Inflammatory Disease by Nataliia Volkova, Mariia Yukhta, Anatoliy Goltsev

“…The number of apoptotic oocytes after stimulation of superovulation in the control group was significantly higher (85.3 ± 5.2%) than that in the animals with therapy (5.7 ± 0.8%). Relative number of fertilized eggs in the group with cMSC therapy was higher by 40% compare to that in the control. …”
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Molecular landscape of lung cancer: insights into therapeutic targets and clinical outcomes by Saloni Mangal, Abhijit Debnath, Rupa Mazumder, Avijit Mazumder, Rajesh Kumar Singh, Jahanvi Sanchitra, S.K. Asif Jan, Pratibha Pandey, Bimlesh Kumar, Anil Kumar Singh

“…Heterogeneity of the disease, resistance to chemotherapy, and side effects such as nausea and vomiting, fatigue, anemia, neuropathy, hair loss, and skin and nail changes are associated with conventional therapeutics such as chemotherapy, radiation therapy, and targeted therapy. Thus, the treatment of the disease urgently requires the discovery of novel therapeutic approaches. …”
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Corrigendum to “Explicitly encoding the cyclic nature of breathing signal allows for accurate breathing motion prediction in radiotherapy with minimal training data” [Phys. Imaging... by Andreas Renner, Ingo Gulyas, Martin Buschmann, Gerd Heilemann, Barbara Knäusl, Martin Heilmann, Joachim Widder, Dietmar Georg, Petra Trnková

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Group A Streptococci-Associated Necrotizing Fasciitis following Cat Bite in an Immunocompromised Patient by Sudheer Nambiar, Asha Karippot, Joe Devasahayam, Tony Oliver

“…Accurate diagnosis and appropriate treatment must include early surgical intervention and antibiotic therapy. Mortality rate is very high and could be even higher in an immunocompromised host. …”
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Mesenchymal Stem Cells as New Therapeutic Agents for the Treatment of Primary Biliary Cholangitis by Aleksandar Arsenijevic, C. Randall Harrell, Crissy Fellabaum, Vladislav Volarevic

“…Accordingly, the alternative approaches, such as mesenchymal stem cell (MSC) transplantation, have been suggested as an effective alternative therapy for these patients. Due to their immunomodulatory characteristics, MSCs are considered as promising therapeutic agents for the therapy of autoimmune liver diseases, including PBC. …”
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Renal Tubular Acidosis an Adverse Effect of PD-1 Inhibitor Immunotherapy by Sandy El Bitar, Chanudi Weerasinghe, Elie El-Charabaty, Marcel Odaimi

“…Immune checkpoint blockade therapy is gaining popularity among oncologists for treatment of solid and hematologic malignancies. …”
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The Tao of Hematopoietic Stem Cells: Toward a Unified Theory of Tissue Regeneration by Kevin D. Bunting, Robert G. Hawley

“…Therefore, HSCs are extremely important targets for gene therapy applications aimed toward the treatment of inherited and acquired blood disorders. …”
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Lymph Drainage of Posttraumatic Edema of Lower Limbs by Ana Carolina Pereira de Godoy, Rodrigo Ocampos Troitino, Maria de Fátima Guerreiro Godoy, José Maria Pereira de Godoy

“…The present study was aimed at evaluating the use of mechanical and manual lymphatic therapy as a treatment for lymphedema resulting from orthopedic surgery that became painful after an episode of erysipelas. …”
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Does Motor Training of the Nonparetic Side Influences Balance and Function in Chronic Stroke? A Pilot RCT by Shanta Pandian, Kamal Narayan Arya, Dharmendra Kumar

“…The objective of the present study was to examine the effect of a motor therapy program primarily involving the nonparetic side on balance and function in chronic stroke. …”
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Autoimmune Gastrointestinal Paralysis: Failure of Conventional Treatment without Immunomodulation by Craig Weinkauf, Sean McPhillips, Robert Krouse, Ira Levine

“…Based on evidence discussed herein, we suggest initiating autoimmune-directed therapy before or simultaneous with cancer-directed therapy.…”
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Laser Photobiomodulation for a Complex Patient with Severe Hydroxyurea-Induced Oral Ulcerations by Marco Cabras, Adriana Cafaro, Alessio Gambino, Roberto Broccoletti, Ercole Romagnoli, Davide Marina, Paolo G. Arduino

“…Conventional therapeutic options aim at reducing vascular and thrombotic risk; low-dose aspirin and phlebotomy are first-line recommendations, for patients at low risk of thrombotic events, whereas cytoreductive therapy, usually hydroxyurea (HU) or interferon alpha, is recommended for high-risk patients. …”
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Dynamic Tracking of Lung Deformation during Breathing by Using Particle Method by Subas Chhatkuli, Seiichi Koshizuka, Mitsuru Uesaka

“…To reduce the side effects and to improve the efficiency of radiation therapy in lung cancer, a pinpoint radiation therapy system is under development. …”
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Calcific Uremic Arteriolopathy in Peritoneal Dialysis Populations by Nicholas New, Janaki Mohandas, George T. John, Sharad Ratanjee, Helen Healy, Leo Francis, Dwarakanathan Ranganathan

“…Current, multimodality treatment involves local wound care, well-controlled calcium, phosphate and parathyroid hormone levels and combination therapy with sodium thiosulfate and hyperbaric oxygen therapy. …”
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Troublesome Tinnitus in Children: Epidemiology, Audiological Profile, and Preliminary Results of Treatment by G. Bartnik, A. Stepien, D. Raj-Koziak, A. Fabijanska, I. Niedzialek, H. Skarzynski

“…In this group 44.1% of the patients demonstrated normal hearing. The success of the therapy after 6 months was estimated on 81.4% of significant improvement. …”
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Rat Sarcoma Virus Family Genes in Acute Myeloid Leukemia: Pathogenetic and Clinical Implications by Shaimaa Khattab, Adriatik Berisha, Natalia Baran, Pier Paolo Piccaluga

“…A deeper comprehension of the disease’s biology and the use of new, targeted therapy approaches could potentially increase cure rates. …”
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