Impact of Pentoxifylline and Vitamin E on Ribavirin-Induced Haemolytic Anaemia in Chronic Hepatitis C Patients: An Egyptian Survey by M. Assem, M. Yousri

“…Selected 200 naïve chronic HCV patients, were randomized to receive either the standard antiviral therapy (peginterferon α-2b and RBV) plus pentoxifylline (800 mg) and high-dose vitamin E (1000 iu) daily (combined group) or received standard antiviral therapy plus placebo only (control group). …”
Get full text

Rehabilitation exercise for treatment of vestibular disorder: A case study by Avraham Feazadeh, Eli Carmeli

“…Four weeks from the start of physical therapy, the patient was free of symptoms, even when her neck was in the extended position.…”
Get full text

Recurrent Catatonia due to Episodic Obsessive-Compulsive Disorder by Soumitra Das, Sakshi Prasad, Palak Atul Fichadia, Abhigan Babu Shrestha, Ozge C. Amuk Williams, Anil Bachu

“…She was also educated about OCD through a series of therapy sessions and exposure and response prevention (ERP) principles. …”
Get full text

Acute Acalculous Cholecystitis: A Rare Presentation of Primary Epstein-Barr Virus Infection in Adults—Case Report and Review of the Literature by Zuhal Yesilbag, Asli Karadeniz, Fatih Oner Kaya

“…Only one patient underwent surgery and all other patients recovered with conservative therapy. The development of AAC should be kept in mind in patients with cholestatic hepatitis due to EBV infection to avoid unnecessary surgical therapy and overuse of antibiotics.…”
Get full text

Predictive Factors in OCT Analysis for Visual Outcome in Exudative AMD by Maria-Andreea Gamulescu, Georgios Panagakis, Carmen Theek, Horst Helbig

“…Reliable predictive factors for therapy outcome may enable treating physicians to counsel their patients more efficiently concerning probability of improvement or time point of discontinuation of a certain therapy. …”
Get full text

Splenic Abscess: An Uncommon Entity with Potentially Life-Threatening Evolution by Mei-Chun Lee, Chun-Ming Lee

“…Patients with splenic abscesses receiving antimicrobial therapy alone were in a relatively high proportion and got a good prognosis especially in patients with small and multiple abscesses.…”
Get full text

Aspirin does not confer protection against major ischemic vascular events in patients diagnosed with rheumatoid arthritis by Chao Gao, Qiqi Hou, Hongxia Cao, Cangtuo Li, Xu Peng, Quanle Han, Shouling Wu, Kangbo Li

“…The relationship between ASA therapy and major ischemic vascular events was analyzed by Cox proportional hazards regression. …”
Get full text

Interferon-gamma: A Potent Antiviral Agent Targeting Macrophages Infected with LP-BM5 Murine Leukemia Virus, the Causative Agent of 'AIDS' in Mice by Jens J Kort, Julie L Eiseman

“…Further, since a lower concentration of each agent was required for efficacy in combination therapy, toxicity associated with single agent therapy may be avoided.…”
Get full text

Vaccines and Immunotherapeutics for the Treatment of Malignant Disease by Joel F. Aldrich, Devin B. Lowe, Michael H. Shearer, Richard E. Winn, Cynthia A. Jumper, Ronald C. Kennedy

“…A number of immunotherapeutic strategies have arisen for the treatment of malignant disease, including various vaccination schemes, cytokine therapy, adoptive cellular therapy, and monoclonal antibody therapy. …”
Get full text

Prospects of MMX Mesalazine in Routine Outpatient Treatment of Ulcerative Colitis by Yu. P. Uspenskiy, S. V. Ivanov, Yu. A. Fominykh

“…The 5-ASA therapy remains the mainstay UC treatment in routine outpatient practice, with prescription rate of 80–90%. …”
Get full text

Rimegepant for the treatment of migraine by Amnon A. Berger, Ariel Winnick, Austin H. Carroll, Alexandra Welschmeyer, Nathan Li, Marc Colon, Antonella Paladini, Giovanni F. Ramírez, Jamal Hasoon, Elyse M. Cornett, Jaehong Song, Giustino Varrassi, Adam M. Kaye, Alan D. Kaye, Latha Ganti

“…Prophylactic therapy may reduce the occurrence of acute migraine attacks in selected patients, but does not completely eliminate it. …”
Get full text

Effect of Oral PUVAsol on the Quality of Life in Indian Patients Having Chronic Plaque Psoriasis by Pratik Gahalaut, Nitin Mishra, Puneet S. Soodan, Madhur K. Rastogi

“…PUVAsol has been successfully used for treating psoriasis instead of standard PUVA therapy in developing countries. However, data for PUVAsol therapy and its effect on QoL in psoriatic patients is meagre. …”
Get full text

A prospective hospital-based study on C-reactive protein as a response predictor of antidepressant treatment in drug naïve patients with major depressive disorder by Didakamiwan Khonglah, Arghya Pal, Nitu Mallik, Debes Ray, Malay Ghosal, Rudraprasad Acharya

“…Aims: This study was conducted to determine the relationship between the level of CRP to remission rates after antidepressant therapy. Methods: Fifty patients of first episode MDD with no past history of antidepressant exposure and other medical comorbidity were recruited after obtaining consent for Escitalopram therapy. …”
Get full text

Congenital Hypothyroidism: An Unusual Combination of Biochemical Abnormalities by Ruchi Mantri, S. B. Bavdekar, Sushma U. Save

“…Following institution of oral thyroxin therapy, the serum bilirubin levels ameliorated (2.9 mg/dl) considerably by 15 days of therapy and the serum levels of AST (40 IU/dl) and ALT (20 IU/dl) got normalized. …”
Get full text

Efficacy of Nivolumab in a Patient with Metastatic Renal Cell Carcinoma and End-Stage Renal Disease on Dialysis: Case Report and Literature Review by Jawaher Ansari, Muhammad Ali, Ashraf Farrag, Arwa M. Ali, Abdulaziz Alhamad

“…In addition, there is uncertainty regarding drug dosing/pharmacokinetics, lack of safety and efficacy data, and potential for increased toxicity when using targeted therapy or immunotherapy for the management of patients with mRCC on dialysis. …”
Get full text

Mesenchymal Stem Cells in Restoration of Fertility at Experimental Pelvic Inflammatory Disease by Nataliia Volkova, Mariia Yukhta, Anatoliy Goltsev

“…The number of apoptotic oocytes after stimulation of superovulation in the control group was significantly higher (85.3 ± 5.2%) than that in the animals with therapy (5.7 ± 0.8%). Relative number of fertilized eggs in the group with cMSC therapy was higher by 40% compare to that in the control. …”
Get full text

Molecular landscape of lung cancer: insights into therapeutic targets and clinical outcomes by Saloni Mangal, Abhijit Debnath, Rupa Mazumder, Avijit Mazumder, Rajesh Kumar Singh, Jahanvi Sanchitra, S.K. Asif Jan, Pratibha Pandey, Bimlesh Kumar, Anil Kumar Singh

“…Heterogeneity of the disease, resistance to chemotherapy, and side effects such as nausea and vomiting, fatigue, anemia, neuropathy, hair loss, and skin and nail changes are associated with conventional therapeutics such as chemotherapy, radiation therapy, and targeted therapy. Thus, the treatment of the disease urgently requires the discovery of novel therapeutic approaches. …”
Get full text

Corrigendum to “Explicitly encoding the cyclic nature of breathing signal allows for accurate breathing motion prediction in radiotherapy with minimal training data” [Phys. Imaging... by Andreas Renner, Ingo Gulyas, Martin Buschmann, Gerd Heilemann, Barbara Knäusl, Martin Heilmann, Joachim Widder, Dietmar Georg, Petra Trnková

Get full text

Group A Streptococci-Associated Necrotizing Fasciitis following Cat Bite in an Immunocompromised Patient by Sudheer Nambiar, Asha Karippot, Joe Devasahayam, Tony Oliver

“…Accurate diagnosis and appropriate treatment must include early surgical intervention and antibiotic therapy. Mortality rate is very high and could be even higher in an immunocompromised host. …”
Get full text

Mesenchymal Stem Cells as New Therapeutic Agents for the Treatment of Primary Biliary Cholangitis by Aleksandar Arsenijevic, C. Randall Harrell, Crissy Fellabaum, Vladislav Volarevic

“…Accordingly, the alternative approaches, such as mesenchymal stem cell (MSC) transplantation, have been suggested as an effective alternative therapy for these patients. Due to their immunomodulatory characteristics, MSCs are considered as promising therapeutic agents for the therapy of autoimmune liver diseases, including PBC. …”
Get full text