Use of Hemadsorption in a Case of Pediatric Toxic Shock Syndrome by Andrea Berkes, Edit Szikszay, János Kappelmayer, Adrienne Kerényi, Tamás Szabó, László Ujhelyi, Krisztina Bari, György Balla, József Balla

“…As previous attempts of immune modulation therapy were unsuccessful, renal replacement therapy was supplemented by the cytokine absorber CytoSorb. …”
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High Dose Ilaprazole/Amoxicillin as First-Line Regimen for Helicobacter pylori Infection in Korea by WonGun Kwack, YunJeong Lim, ChiYeon Lim, David Y. Graham

“…The eradication rate of Helicobacter pylori (H. pylori) following standard triple therapy has declined over the past few decades. This study has determined whether high dose dual therapy (PPI and amoxicillin) is adequate for eradicating H. pylori in Korea. …”
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Predictors of infliximab efficacy in patients with severe attack of ulcerative colitis by A. O. Golovenko, I. L. Khalif, O. V. Golovenko, V. V. Veselov

“…Aim of investigation. Biological therapy by monoclonal antibodies against tumor necrosis factor (infliximab) allows to avoid colectomy at steroid-resistant severe attack of ulcerative colitis. …”
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Trends in prescribing sodium‐glucose cotransporter 2 inhibitors for individuals with type 2 diabetes with and without cardiovascular‐renal disease in South Korea, 2015–2021 by Kyoung Hwa Ha, Soyoung Shin, EunJi Na, Dae Jung Kim

“…However, the proportion of individuals receiving monotherapy or dual combination therapy decreased by 9.2 percentage points, whereas the proportion prescribed triple or more combination therapy increased. …”
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Biologic Agents in Crohn’s Patients Reduce CD4+ T Cells Activation and Are Inversely Related to Treg Cells by Eliane Aparecida Rosseto-Welter, Leticia D’argenio-Garcia, Filipa Blasco Tavares Pereira Lopes, Ana Eduarda Zulim Carvalho, Fernando Flaquer, Vanessa Severo-Lemos, Claudia Concer Viero Nora, Flavio Steinwurz, Lucas Pires Garcia Oliveria, Thiago Aloia, Luiz Vicente Rizzo, Cristóvão Luis Pitangueira Mangueira, Karina Inacio Carvalho

“…There are two main treatments for Chron’s disease: biological therapy and nonbiological therapy. Biological agent therapy (e.g., anti-TNF) is the most frequently prescribed treatment; however, it is not universally accessible. …”
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Safety and Efficacy of Anticoagulation in Patients with Cirrhosis: A Meta-Analysis by Huan Chen, Jiaming Lei, Sicheng Liang, Gang Luo, Mingming Deng, Muhan Lü

“…We performed a meta-analysis to evaluate the safety and efficacy of anticoagulant therapy and prophylactic anticoagulant therapy in cirrhosis patients with (/without) portal vein thrombosis. …”
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The Diagnosis and Treatment of Infantile Nystagmus Syndrome (INS) by Sangeeta Khanna, Louis F. Dell'Osso

“…Determination of the direct effects of peripheral and central INS therapies can only be made by pre- and post-therapy comparisons of the nystagmus characteristics, specifically of the quality of the foveation periods within each cycle. …”
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Rectal Application of Ozone to Patients with Diabetes Mellitus by Omar Morejón Barroso, Imandra María García Menéndez, Leticia Varela Castro, Ernesto Julio Bernal Valladares

“…<br /><strong>Conclusions:</strong> rectal ozone therapy can be used as a complementary therapy to the conventional treatment of patients with diabetes mellitus, since it improves glycemia parameters.…”
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The Role of Clopidogrel in 2020: A Reappraisal by Giuseppe Patti, Giuseppe Micieli, Claudio Cimminiello, Leonardo Bolognese

“…This review discusses the available evidence concerning antiplatelet therapy in patients with CVD, with a focus on the role of clopidogrel. …”
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Recurrent Massive Hydrothorax in a Patient with Decompensated Liver Cirrhosis by K. S. Zemlyanukhina, I. N. Tikhonov, M. S. Zharkova, O. Yu. Kiseleva, R. Т. Rzayev, V. T. Ivashkin

“…The patient received effective antiviral therapy with drugs using an interferon-free regimen. …”
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Biomarkers in metastatic castration-resistant prostate cancer for efficiency of immune checkpoint inhibitors by Zixi Wu, Junbiao Zhang, Le Li, Zhihua Wang, Chunguang Yang

“…In cases where traditional first-line treatments prove ineffective, the potential of immune checkpoint blockade (ICB) therapy emerges as a promising approach for managing mCRPC. …”
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A rare neurosurgical emergency: case report of spontaneous lumbar subdural empyema by Svetozar Stanković, Milan Lepić, Ivan Bogićević, Jadranka Stanković, Goran Pavlicević

“…Initial broad-spectrum antibiotic therapy was followed by targeted therapy (vancomycin and levofloxacin) for three weeks, and then oral cephalosporins for four weeks. …”
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Tumour Debulking for Esophageal Cancer - Thermal Modalities by David Fleischer

“…Esophageal cancer usually is discovered at a late stage and curative therapy seldom is possible. The prognosis is poor and most therapy is palliative. …”
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Therapeutic applications of artemisinin in ophthalmic diseases by Hao Sun, Ping Zhao, Lianghui Zhao, Zhizhong Zhao, Haoyu Chen, Cong Ren, Bin Guo

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Loop33 × 123 CAR-T targeting CD33 and CD123 against immune escape in acute myeloid leukemia by Haotian Ma, Zhifeng Yan, Runxia Gu, Yingxi Xu, Shaowei Qiu, Haiyan Xing, Kejing Tang, Zheng Tian, Qing Rao, Min Wang, Jianxiang Wang

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Refractory myasthenia gravis treated with autologous hematopoietic stem cell transplantation by Benjamin Beland, Jan Storek, Liam Quartermain, Christopher Hahn, C. Elizabeth Pringle, Pierre R. Bourque, Michael Kennah, Natasha Kekre, Christopher Bredeson, David Allan, Kareem Jamani, Christopher White, Harold Atkins

“…All patients had severe MG refractory to multiple therapies. Stem cells were mobilized with cyclophosphamide and granulocyte colony‐stimulating factor. …”
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Comparison of pathophysiology in subclinical hyperthyroidism with different etiologies by Hanna Deguchi-Horiuchi, Mitsuru Ito, Sawako Takahashi, Kazuyoshi Kousaka, Mako Hisakado, Shuji Fukata, Takumi Kudo, Eijun Nishihara, Mitsushige Nishikawa, Akira Miyauchi, Takashi Akamizu

“…The effects of endogenous SHyper and TSH suppression therapy on target organ function are different. Although the serum thyroid hormone profile is similar to that of the thyrotoxic state, athyreotic patients receiving TSH suppression therapy with mildly suppressed serum TSH levels are not thyrotoxic.…”
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Advancing precision medicine: the transformative role of artificial intelligence in immunogenomics, radiomics, and pathomics for biomarker discovery and immunotherapy optimization by Luchen Chang, Jiamei Liu, Jialin Zhu, Shuyue Guo, Yao Wang, Zhiwei Zhou, Xi Wei

“…In radiomics, AI can analyze high-dimensional features from computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography/computed tomography (PET/CT) images to discover imaging biomarkers associated with tumor heterogeneity, treatment response, and disease progression, thereby enabling non-invasive, real-time assessments for personalized therapy. Pathomics leverages AI for deep analysis of digital pathology images, and can uncover subtle changes in tissue microenvironments, cellular characteristics, and morphological features, and offer unique insights into immunotherapy response prediction and biomarker discovery. …”
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The Christmas Season as a Risk Factor for Chronic Obstructive Pulmonary Disease Exacerbations by Neil W Johnston, Andrew McIvor, Kim Lambert Reg N, Justina M Greene, Pat Hussac, Maria Gerhardsson de Verdier, Tim Higenbottam, Jonathan Lewis, Paul Newbold, Athula Herath, Martin Jenkins

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Genetically Engineered Islets and Alternative Sources of Insulin-Producing Cells for Treating Autoimmune Diabetes: Quo Vadis? by Feng-Cheng Chou, Shing-Hwa Huang, Huey-Kang Sytwu

“…Islet transplantation is a promising therapy for patients with type 1 diabetes that can provide moment-to-moment metabolic control of glucose and allow them to achieve insulin independence. …”
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