Antiangiogenic therapy with recombinant human endostatin may improve blood perfusion of cervical node with necrosis in nasopharyngeal carcinoma patients: a preliminary study by using contrast-enhanced ultrasound by Zhendong Yang, Huimin Xiao, Xigui Li, Zhuxin Wei, Min Kang, Rensheng Wang, Jianyuan Huang

Subjects: “…antiangiogenic therapy…”
Get full text

Dynamics of Somatic and Comorbid Mental Disorders (Distress, Anxiety, Somatisation and Depression) in Patients with Irritable Bowel Syndrome during Therapy with Alimemazine: Results of an Non-Interventional Observational Programme (“Terra”) by V. T. Ivashkin, O. Z. Okhlobystina, M. V. Mayevskaya, O. S. Shifrin, Z. A. Mamieva, Yu. E. Azimova

“…This study is aimed at investigating the efficacy and safety of alimemazine (Teraligen®) therapy in patients with irritable bowel syndrome (IBS) associated with comorbid mental disorders (distress, anxiety, somatisation and depression).Materials and methods. …”
Get full text

Comparative evaluation of high-flow nasal cannula (HFNC) and conventional oxygen therapy (COT) in infants after non-cardiac surgery: Study protocol of a randomized controlled trial. by Diwei Zhang, Tianqing Gong, Qinghua Huang, Qianqian Zhang, Kai Liu, Jia Li, Hai Yu, Yu Cui

“…If favorable evidence is obtained, HFNC could be adopted as first-line oxygen therapy for infants following non-cardiac surgery.…”
Get full text

Radiation-Induced Peripheral Malignant Nerve Sheath Tumor Arising from Vestibular Schwannoma after Linac-Based Stereotactic Radiation Therapy: A Case Report and Review of Literatures by Putipun Puataweepong, Taweesak Janwityanujit, Noppadol Larbcharoensub, Mantana Dhanachai

“…Regarding the uncertainty of carcinogenesis risk, we should still practice radiation therapy with caution, especially in the young patient with tumor predisposition syndrome. …”
Get full text

Influence of Anti-TNF and Disease Modifying Antirheumatic Drugs Therapy on Pulmonary Forced Vital Capacity Associated to Ankylosing Spondylitis: A 2-Year Follow-Up Observational Study by Alberto Daniel Rocha-Muñoz, Aniel Jessica Leticia Brambila-Tapia, María Guadalupe Zavala-Cerna, José Clemente Vásquez-Jiménez, Liliana Faviola De la Cerda-Trujillo, Mónica Vázquez-Del Mercado, Norma Alejandra Rodriguez-Jimenez, Valeria Díaz-Rizo, Viviana Díaz-González, Ernesto German Cardona-Muñoz, Ingrid Patricia Dávalos-Rodríguez, Mario Salazar-Paramo, Jorge Ivan Gamez-Nava, Arnulfo Hernan Nava-Zavala, Laura Gonzalez-Lopez

Get full text

The Rate of Prescribing Gastrointestinal Prophylaxis with Either a Proton Pump Inhibitor Or an H2-Receptor Antagonist in Nova Scotia Seniors Starting Nonsteroidal Anti-Inflammatory Drug Therapy by Bogdan Superceanu, Sander Veldhuyzen van Zanten, Chris Skedgel, Michael Shepherd, Ingrid Sketris

“…For patients at increased risk of NSAID-related GI complications, prophylaxis with either a nonselective NSAID plus gastroprotective agent (GPA) or, alternatively, therapy with a cyclooxygenase-2 selective inhibitor with or without a GPA such as a proton pump inhibitor (PPI), is recommended.…”
Get full text

A Real World Report on Intravenous High-Dose and Non-High-Dose Proton-Pump Inhibitors Therapy in Patients with Endoscopically Treated High-Risk Peptic Ulcer Bleeding by Lung-Sheng Lu, Sheng-Chieh Lin, Chung-Mou Kuo, Wei-Chen Tai, Po-Lin Tseng, Kuo-Chin Chang, Chung-Huang Kuo, Seng-Kee Chuah

“…The optimal dose of intravenous proton-pump inhibitor (PPI) therapy for the prevention of peptic ulcer (PU) rebleeding remains controversial. …”
Get full text

Efficacy and safety of dexamethasone or triamcinolone in combination with anti-vascular endothelial growth factor therapy for diabetic macular edema: A systematic review and meta-analysis with trial sequential analysis. by Bo Zhou, Hua Liu, Feng Xiong

“…Clinicians should weigh the pros and cons comprehensively when implementing combined therapy.…”
Get full text

RECIST 1.1 versus mRECIST for assessment of tumour response to molecular targeted therapies and disease outcomes in patients with hepatocellular carcinoma: a systematic review and meta-analysis by Yao Yang, Yuping Bai, Hongli Yu, Qiang Zhu, Xiaoyu Xie, Yuemin Feng

“…Which one is better to evaluate efficacy after molecular targeted therapies in hepatocellular carcinoma (HCC) patients is still controversial. …”
Get full text

Myeloid Neoplasms with t(5;12) and ETV6-ACSL6 Gene Fusion, Potential Mimickers of Myeloid Neoplasm with PDGFRB Rearrangement: Case Report with Imatinib Therapy and Review of the Literature by Javier De Luca-Johnson, Jose I. Ruades Ninfea, Lauren Pearson, Joanna Conant, Ronald Bryant, Neil A. Zakai, Mary E. Tang

“…Our patient was found to be nonresponsive to imatinib therapy.…”
Get full text

Effect of mechanical debridement with and without adjunct antimicrobial photodynamic therapy for the treatment of peri-implant disease in obese patients: A systematic review and meta-analysis of randomized controlled trials by Sultan Albeshri, Raed AlRowis

Subjects: “…Antimicrobial photodynamic therapy…”
Get full text

Comparisons of open surgical repair, thoracic endovascular aortic repair, and optimal medical therapy for acute and subacute type B aortic dissection: a systematic review and meta-analysis by Jianping Liu, Xiaohong Chen, Juan Xia, Long Tang, Yongheng Zhang, Lin Cao, Yong Zheng

Subjects: Get full text

Comparative efficacy of clopidogrel-aspirin combination therapy versus aspirin monotherapy in preventing recurrent events in transient ischemic attack and minor stroke: a systematic review and meta-analysis by Ahmad Mujtaba Bhutto, Rana Ali Raza, Mohammad Bilal Abbasi, Iman Jauhar, Naeemullah Arbani, Muhammad Mubashir, Abdul Raheem, Taha Basit Ameen, Syed Muhammad Sinaan Ali

Subjects: Get full text

Hydroxychloroquine Therapy Led to the Diagnosis of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in an Elderly Patient with COVID-19 Involvement: A Case Report and Review of the Literature by Razieh Taghizadeh-Sarvestani, Hamid Reihani, Ali Ghanei-Shahmirzadi, Alireza Keshtkar, Parsa Yazdanpanahi

Get full text

Effects of Clinicopathological Characteristics on the Survival of Patients Treated with PD-1/PD-L1 Inhibitor Monotherapy or Combination Therapy for Advanced Cancer: A Systemic Review and Meta-Analysis by Yuhan Wei, Yongfu Li, Qi Du, Xinyi Peng, Jiangtao Jin, Hong Guo, Yongyan Li, Qin Li

“…EGFR status for monotherapy and sex and smoking status for combination therapy were important predictors of survival benefits.…”
Get full text

Density functional theory and molecular dynamics simulation-based bioprospection of Agathosma betulina essential oil metabolites against protein tyrosine phosphatase 1B for interventive antidiabetic therapy by Oluwaseye Adedirin, Rukayat A. Abdulsalam, Khadeejah O. Nasir-Naeem, Ayenitaju A. Oke, Akolade O. Jubril, Saheed Sabiu

Get full text

Is C-reactive protein sufficient to guide antimicrobial therapy for lower respiratory tract infections among children?... by Chris A Rees, Prashant Mahajan, Quique Bassat

Get full text

Complete PSA Remission without Adjuvant Therapy after Secondary Lymph Node Surgery in Selected Patients with Biochemical Relapse after Radical Prostatectomy and Pelvic Lymph Node Dissection by Alexander Winter, Jens Uphoff, Rolf-Peter Henke, Friedhelm Wawroschek

“…Materials and Methods. 11 patients with PSA relapse (mean 3.02 ng/mL, range 0.5–9.55 ng/mL) after radical prostatectomy without adjuvant therapy were included. Suspicious LN (1–3) detected on choline PET/CT and nearby LN were openly dissected (09/04–02/11). …”
Get full text

Acupuncture Combined with Traditional Chinese Medicine and Drug Therapy for the Treatment of Cerebral Infarction (Phlegm-Blood Stasis Syndrome) and Carotid Atherosclerotic Plaque: A Preliminary Randomized Controlled Study by Wentong Wang, Zhuli Liu, Yongxiong Wu

“…Here, we performed a randomized controlled study to investigate the effectiveness of acupuncture combined with drug therapy (TCM and Western) to treat cerebral infarction (phlegm-blood stasis syndrome) and CAP. …”
Get full text

The impact of neuroscience education therapy, behavioral economics, and digital navigators on patient migraine treatment adherence to a mobile health application: a prospective pilot randomized controlled trial by Mia T. Minen, Erin K. Waire, John Torous, Jessica Fishman, Richard B. Lipton, Scott W. Powers

“…Abstract Mobile health (mHealth) tools can be used to deliver nonpharmacologic therapies to patients with migraine. However, mHealth studies often report poor treatment adherence. …”
Get full text