Rapid diagnostic testing combined with an immediate infectious disease consultation increases the rate of septic intensive care unit patients on targeted antibiotic therapy by Evelyn Kramme, Nadja Käding, Nadja Käding, Tobias Graf, Karolin Schmoll, Heidi Linnen, Katharina Nagel, Esther Grote-Levi, Susanne Hauswaldt, Dennis Nurjadi, Dennis Nurjadi, Jan Rupp, Jan Rupp, Jan Rupp

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Mechanistic insights into 5-aminolevulinic acid photodynamic therapy for acne vulgaris: targeting lipogenesis via the OLR1-Wnt/β-catenin pathway by Jia Yan, Linglin Zhang, Qingyu Zeng, Yitao Qian, Ke Li, Xiaojing Liu, Yun Wu, Yu Yan, Haiyan Zhang, Szeman Cheung, Jia Liu, Ronald Sroka, Xiuli Wang, Lei Shi

“…While 5-aminolevulinic acid photodynamic therapy (ALA-PDT) is clinically effective in treating moderate to severe acne, the molecular mechanisms underlying its therapeutic effects remain largely unexplored. …”
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Virtual reality support during systemic cancer therapy to improve anxiety/depressive symptoms and reduce toxicity in patients with gastrointestinal cancers—OncoVR by S. Kasper, S. Liszio, K. Schorrmann, M. Gerigk, S. Jovic, O. Basu, K. Kostbade, B. Goraus, A. Elsakka, B. Puladi, J. Kleesiek, M. Schuler, G. Luijten, J. Egger

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Addressing the limitations of the regulatory landscape in South Africa regarding advanced cell and gene therapies and related sectors involving human cells, tissues and organs by I M Viljoen, M S Pepper

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MAZ-mediated tumor progression and immune evasion in hormone receptor-positive breast cancer: Targeting tumor microenvironment and PCLAF+ subtype-specific therapy by Gaofeng Ni, Yuwei Sun, Hongling Jia, Zhikai Xiahou, Yumeng Li, Fu Zhao, Hongyan Zang

“…Despite advancements in endocrine therapies, patients with advanced HR+BC often faced poor outcomes due to the development of resistance to treatment. …”
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Healthcare Resource Utilization and Costs Among Commercially Insured Patients With Advanced or Recurrent Endometrial Cancer Initiating First-Line Therapy in the United States by Monica Kobayashi, Jamie Garside, Joehl Nguyen

“…Treatment characteristics, HCRU, and costs were assessed from the first claim in the patient record for 1L therapy for advanced or recurrent EC (index) until initiation of a new anti-cancer therapy, disenrollment from the database, or the end of data availability. …”
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Stable Gastric Pentadecapeptide BPC 157 as Therapy After Surgical Detachment of the Quadriceps Muscle from Its Attachments for Muscle-to-Bone Reattachment in Rats by Danijel Matek, Irena Matek, Eva Staresinic, Mladen Japjec, Ivan Bojanic, Alenka Boban Blagaic, Lidija Beketic Oreskovic, Ivana Oreskovic, Tihomil Ziger, Tomislav Novinscak, Ivan Krezic, Sanja Strbe, Martin Drinkovic, Filip Brkic, Jelena Popic, Anita Skrtic, Sven Seiwerth, Mario Staresinic, Predrag Sikiric, Ivica Brizic

“…Background: This is a novel rat study using native peptide therapy, focused on reversing quadriceps muscle-to-bone detachment to reattachment and stable gastric pentadecapeptide BPC 157 per-oral therapy for shared muscle healing and function restoration. …”
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N-terminal pro-B-type natriuretic peptide as a predictive marker of the outcomes of fibrinolytic therapy in acute ST-elevation myocardial infarction by Amit Kumar, Shweta Tanwar, Rajesh Chetiwal

“…Materials and Methods: In this prospective study, we enrolled individuals with acute STEMI who underwent fibrinolytic therapy. Plasma N-terminal-proBNP (NT-proBNP) levels were assessed upon admission. …”
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Supervised vs. Self-Managed Exercise Therapy for Improving Shoulder Function After Traumatic Dislocation and Sprain: A Systematic Review and Meta-Analysis by Daniel Koska, Robert Zetzsche, Tobias A. Mayer, Christian Maiwald

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Safety and efficacy of anti-CD30 CAR-T cell therapy in relapsed/refractory classic Hodgkin lymphoma: a systematic review and meta-analysis by Fanqiao Meng, Maoyuan Xiang, Yu Liu, Dongfeng Zeng

“…Abstract Background Relapsed/refractory classic Hodgkin lymphoma (R/R cHL) remains challenging to treat, and anti-CD30 chimeric antigen receptor T (CAR-T) cell therapy may be effective. This meta-analysis investigates the efficacy and safety of anti-CD30 CAR-T cell therapy for treating R/R cHL. …”
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Case Report: Combination of focal vibration therapy and botulinum toxin injections to treat equinus gait in a child with unilateral spastic cerebral palsy by Christophe Boulay, Christophe Boulay, Christophe Boulay, Jacques-Olivier Coq, Morgan Sangeux, Morgan Sangeux, Guillaume Authier, Guillaume Authier, Alexis Ulian, Alexis Ulian, Maud Pradines, Maud Pradines, Marjolaine Baude, Marjolaine Baude, Béatrice Desnous, Jean-Luc Jouve, Jean-Luc Jouve, Bernard Parratte, Emilie Peltier, Sébastien Pesenti, Jean-Michel Gracies, Jean-Michel Gracies

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Estimating the Cost-Effectiveness of Tumor Treating Fields (TTFields) Therapy with an Immune Checkpoint Inhibitor or Docetaxel in Metastatic Non-Small Cell Lung Cancer by Furnback W, Wu E, Koh CYC, Nino de Rivera Guzman JF, Kruhl C, Kotecha R, Wang BC

“…Tumor Treating Fields (TTFields) therapy extended survival in patients with metastatic non-small cell lung cancer (NSCLC) on or after platinum-based therapy. …”
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Which combination of medical expulsive therapy is more effective for treatment of distal ureteral stone in adults?... by Maryam Taheri, Nasrin Borumandnia, Hamidreza Abdi, Amir H Kashi, Setareh Nourani, Sogand Sheikholeslami, Yasamin Maleki Gilvaei, Pardis Ziaeefar, Abbas Basiri

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Short‐ and Long‐Term Efficacy of Hyperbaric Oxygen Therapy in Irradiated Breast Cancer Patients With Long‐Standing Lymphedema: A Prospective Case Series by Imjai Chitapanarux, Siriarrayapa Chachvarat, Patumrat Sripan, Thienchai Pattarasakulchai, Nuttaya Pattamapaspong, Thanat Kanthawang, Montana Buntragulpoontawee

“…This prospective case series aimed to document the short‐ and long‐term efficacy of this therapy, focusing on the arm volume and functional assessment in breast cancer patients with a history of long‐standing lymphedema for more than 2 years. …”
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Systematic review and bayesian network meta-analysis: comparative efficacy and safety of six commonly used biologic therapies for moderate-to-severe Crohn’s disease by Haohang Su, Haohang Su, Shengwei Xiao, Zhiqing Liang, Zhiqing Liang, Tianrong Xun, Jinfang Zhang, Jinfang Zhang, Xixiao Yang, Xixiao Yang

“…For TNF antagonist-experienced patients, Ustekinumab and Risankizumab may be preferred biologic agents for induction therapy. Risankizumab potentially has the lowest safety risk worth exploring in induction therapy. …”
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High peripheral T cell diversity is associated with lower risk of toxicity and superior response to dual immune checkpoint inhibitor therapy in patients with metastatic NSCLC by Alexandre Reuben, Mehmet Altan, Latasha Little, Jianjun Zhang, Ajay Sheshadri, Hai T Tran, Mara B Antonoff, Stephen G Swisher, John V Heymach, Saumil Gandhi, Natalie Vokes, Ziyi Li, Ruoxing Li, Runzhe Chen, Joshua Baguley, Jefferson Sinson, Greg Lizee

“…Journal for ImmunoTherapy of Cancer…”
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A Granulocyte-Specific Protein S100A12 as a Potential Prognostic Factor Affecting Aggressiveness of Therapy in Patients with Juvenile Idiopathic Arthritis by Krzysztof Orczyk, Elzbieta Smolewska

“…S100A12 may become an important factor influencing decisions on aggressiveness of JIA therapy. Further elaboration on the clinical algorithm is necessary for that protein to be included in everyday practice.…”
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Predictive value of monocyte-to-high-density lipoprotein-cholesterol ratio (MHR) for poor prognosis after intravenous thrombolytic therapy for acute ischaemic stroke by Yinglei Li, Lingyun Xi, Litao Li

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Anemia among HIV-Infected Patients Initiating Antiretroviral Therapy in South Africa: Improvement in Hemoglobin regardless of Degree of Immunosuppression and the Initiating ART Regimen by Simbarashe Takuva, Mhairi Maskew, Alana T. Brennan, Ian Sanne, A. Patrick MacPhail, Mathew P. Fox

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Gas Expansion Three Days after Pars Plana Vitrectomy with Sulfur Hexafluoride 20% Tamponade following Carbon Monoxide Toxicity and Oxygen Therapy by Mojtaba Abrishami, Mehrdad Motamed Shariati, Ali Bolouki, Ghodsieh Zamani

“…To report an unusual case of gas expansion following oxygen therapy in a patient with sulfur hexafluoride (SF6) 20% tamponade after pars plana vitrectomy. …”
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