Mechanistic insights into 125I seed implantation therapy for Cholangiocarcinoma: focus on ROS-Mediated apoptosis and the role of GPX2 by Jun Luo, Zheng Yao, Weiren Liang, Danjun Song, Hui Zeng, Yi Jiang, Zhehan Bao, Jiaping Zheng, Yinan Ding

“…Conclusion 125I seed implantation therapy exerts therapeutic effects on CCA by inducing ROS-mediated apoptosis. …”
Get full text

Impact of patient compliance with inhaler therapy on chronic obstructive pulmonary disease severity: a rural tertiary care perspective by Nandakishore K. S., Preethiraj Ballal, Anirudha Katipalla, Shruthi Rai P., Supreetha T., Dixith T., Sanjay Srinivas, Shree Dhanusha, Pramod Pujar, Sushmitha Sudeesh, Vignesh T. M.

Get full text

Risk of Subclinical Hypothyroidism in Breast Cancer Patients Treated With CT-Guided Radiation Therapy: A Prospective Observational Study by Amdisen L, Brink C, Lorenzen EL, Roenlev JD, Ewertz M, Cronin-Fenton D

“…Lau Amdisen,1 Carsten Brink,2,3 Ebbe Laugaard Lorenzen,2,3 Jeanette Dupont Roenlev,4 Marianne Ewertz,2 Deirdre Cronin-Fenton1 1Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark; 2Department of Clinical Research, University of Southern Denmark, Odense, Denmark; 3Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Odense, Denmark; 4Department of Oncology, Odense University Hospital, Odense, DenmarkCorrespondence: Lau Amdisen, Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Olof Palmes Allé 43-45, Aarhus N, 8200, Denmark, Tel +45 8716 8229, Email amdisen@clin.au.dkPurpose: The thyroid gland is an organ at risk in breast cancer survivors who receive radiation therapy to the supraclavicular lymph nodes. We investigated the effect of radiation dose to the thyroid gland on the incidence of hypothyroidism in early-stage breast cancer patients treated with CT-guided radiation therapy.Patients and Methods: We recruited women aged ≤ 75 years diagnosed with breast cancer from March 2016 through August 2017 at Odense University Hospital, Denmark. …”
Get full text

Oligoclonality of TRBC1 and TRBC2 in T cell lymphomas as mechanism of primary resistance to TRBC-directed CAR T cell therapies by Benjamin Thiele, Paul Schmidt-Barbo, Christoph Schultheiss, Edith Willscher, Thomas Weber, Mascha Binder

Get full text

Serum fatty acid-binding protein 3 levels differentiate active from inactive myositis and correlate with response to therapy by Latika Gupta, Sanjukta Majumder, Amita Aggarwal, Ramnath Misra, Able Lawrence

Get full text

Effect of Community-Based Occupational Therapy on Health-Related Quality of Life and Engagement in Meaningful Activities of Women with Breast Cancer by Daiva Petruseviciene, Deive Surmaitiene, Daiva Baltaduoniene, Egle Lendraitiene

“…Occupational Therapy International…”
Get full text

Comparisons of transcranial alternating current stimulation and repetitive transcranial magnetic stimulation treatment therapy for insomnia: a pilot study by Yifei Zhu, Kai Yuan, Yongjian Guo, Jiayi Liu, Xumeng Zhao, Xiaoyang Liu, Lirong Yue, Xiaona Sheng, Dahua Yu, Ziqiang Shao

Get full text

The Impact of Antiretroviral Therapy on Liver Function Among Pregnant Women Living with HIV in Co-Existence with and Without Pre-Eclampsia by Kay-Lee E. Strauss, Wendy N. Phoswa, Kabelo Mokgalaboni

Subjects: “…antiretroviral therapy…”
Get full text

Effects of Nonsurgical Periodontal Therapy on Clinical Response, Microbiological Profile, and Glycemic Control in Malaysian Subjects with Type 1 Diabetes by Samira Mukhtar Buzinin, Aied Mohammed Alabsi, Alexander Tong Boon Tan, Vui King Vincent-Chong, Dasan Swaminathan

“…Periodontal parameters and plaque samples for microbiological evaluation were done at baseline, 2 and 3 months after nonsurgical periodontal therapy. Blood samples were taken from only the test group and evaluated for HbA1c at baseline and 3 months after periodontal therapy. …”
Get full text

Predictors of biochemical and structural response to medical therapy in patients with active acromegaly following surgery: a real-world perspective by Maryam Rafieemanesh, Manizhe Ataee Kachuee, Ali Zare Mehrjardi, Alireza Khajavi, Mohammad Ghorbani, Mohammad Reza Mohajeri-Tehrani, Nahid Hashemi-Madani, Mohammad E. Khamseh

“…We aimed to explore the potential role of select clinical, biochemical, and radiological factors in predicting biochemical and structural responses to medical therapy in a real-world setting. Methods This retrospective cohort study included 58 patients with active acromegaly following surgery treated with Octreotide long-acting release (LAR) (± Cabergoline). …”
Get full text

Antimalarial Combination Therapies Increase Gastric Ulcers Through an Imbalance of Basic Antioxidative‑Oxidative Enzymes in Male Wistar Rats. by Kalange, Muhamudu, Nansunga, Miriam, Keneth Iceland, Kasozi, Kasolo, Josephine, Namulema, Jackline, Kasande Atusiimirwe, Jovile, Tiyo Ayikobua, Emanuel, Ssempijja, Fred, Munanura, Edson Ireeta, Matama, Kevin, Semuyaba, Ibrahim, Zirintunda, Gerald Gerald, Okpanachi, Alfred Omachonu

“…Results: Antimalarial combination therapies were associated with a high gastric ulcer index than a single antimalarial agent, Artesunate. …”
Get full text

Evaluation of EGFR-TKIs and ICIs treatment stratification in non-small cell lung cancer using an encrypted multidimensional radiomics approach by Xingping Zhang, Xingting Qiu, Yue Zhang, Qingwen Lai, Yanchun Zhang, Guijuan Zhang

Subjects: Get full text

Switching to Dolutegravir/lamivudine or Bictegravir/Emtricitabine/Tenofovir alafenamide. A comparative real-world study by Hernando Knobel, Esperanza Cañas-Ruano, Ana Guelar, Pablo Knobel, Judit Villar-García, Alicia González-Mena, Ceclia Canepa, Itziar Arrieta-Aldea, Augustin Marcos, Agustí Abalat-Torrres, Roberto Güerri-Fernández

Subjects: “…switching antiretroviral therapy…”
Get full text

A systematic review of outcomes reported in studies to optimise the medication use of patients at hospital discharge by Joke Wuyts, Veerle Foulon, Samuel Sebastian Allemann, Fabienne Boeni

Subjects: Get full text

Case report: Unraveling a unique case of male occult breast cancer with axillary intricacies and a comprehensive literature dive by Xintong Xie, Xiangyi Kong, Xiangyi Kong, Hongnan Jiang, Jidong Gao, Jidong Gao

Subjects: Get full text

Risk factors and treatment approaches to seasonal affective disorder: a review by V. Jurgaitytė, N. Khawaja, J. Dijokas, P. Rimkevičiūtė

Subjects: Get full text